Melanoma differentiation-associated gene 5 in zebrafish provoking higher interferon-promoter activity through signalling enhancing of its shorter splicing variant

Immunology

Volumn 141, Issue 2, 2014, Pages 192-202

  Zou, Peng Fei ^a,b,c   Chang, Ming Xian ^a   Xue, Na Na ^a   Liu, Xue Qin ^d   Li, Jun Hua ^a   Fu, Jian Ping ^a   Chen, Shan Nan ^a   Nie, Pin ^a,c  

^a INSTITUTE OF HYDROBIOLOGY   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c JIMEI UNIVERSITY   (China)

^d HUAZHONG AGRICULTURAL UNIVERSITY   (China)

Author keywords

Melanoma differentiation associated gene 5; Mitochondrial antiviral signalling protein; Splicing variant; Type I interferon; Zebrafish

Indexed keywords

INTERFERON; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5A PROTEIN; MELANOMA DIFFERENTIATION ASSOCIATED GENE 5B PROTEIN; MITOCHONDRIAL ANTIVIRAL SIGNALLING PROTEIN; MITOCHONDRIAL PROTEIN; RETINOIC ACID INDUCIBLE PROTEIN I; RNA; UNCLASSIFIED DRUG;

ALTERNATIVE RNA SPLICING; ANIMAL CELL; ARTICLE; CELL LINE; CONTROLLED STUDY; EDWARDSIELLA TARDA; EMBRYO; GENETIC TRANSCRIPTION; GRAM NEGATIVE BACTERIUM; HUMAN; HUMAN CELL; INFECTION PREVENTION; INTERFERON INDUCTION; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN INTERACTION; RNA VIRUS; SPRING VIRAEMIA OF CARP VIRUS; SPRING VIREMIA OF CARP; UPREGULATION; ZEBRA FISH;

MELANOMA DIFFERENTIATION-ASSOCIATED GENE 5; MITOCHONDRIAL ANTIVIRAL SIGNALLING PROTEIN; SPLICING VARIANT; TYPE I INTERFERON; ZEBRAFISH;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; AMINO ACID SEQUENCE; ANIMALS; CELL LINE; DEAD-BOX RNA HELICASES; HEK293 CELLS; HUMANS; INTERFERON TYPE I; MOLECULAR SEQUENCE DATA; PROMOTER REGIONS, GENETIC; SIGNAL TRANSDUCTION; VIRUS DISEASES; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84891894371     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/imm.12179     Document Type: Article

References (42)

1. Meylan E, Tschopp J, Karin M. Intracellular pattern recognition receptors in the host response. Nature 2006; 442:39-44.
2. Mogensen TH. Pathogen recognition and inflammatory signaling in innate immune defenses. Clin Microbiol Rev 2009; 22:240-73.
3. Kawai T, Akira S. The roles of TLRs, RLRs and NLRs in pathogen recognition. Int Immunol 2009; 21:317-37.
4. Zou J, Chang M, Nie P, Secombes CJ. Origin and evolution of the RIG-I like RNA helicase gene family. BMC Evol Biol 2009; 9:85.
5. Yoneyama M, Kikuchi M, Matsumoto K et al. Shared and unique functions of the DExD/H-box helicases RIG-I, MDA5, and LGP2 in antiviral innate immunity. J Immunol 2005; 175:2851-8.
6. Saito T, Hirai R, Loo YM et al. Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2. Proc Natl Acad Sci USA 2007; 104:582-7.
7. Kawai T, Takahashi K, Sato S et al. IPS-1, an adaptor triggering RIG-I-and Mda5-mediated type I interferon induction. Nat Immunol 2005; 6:981-8.
8. Johnson CL, Gale M Jr. CARD games between virus and host get a new player. Trends Immunol 2006; 27:1-4.
9. Xu LG, Wang YY, Han KJ, Li LY, Zhai Z, Shu HB. VISA is an adapter protein required for virus-triggered IFN-β signaling. Mol Cell 2005; 19:727-40.
10. Yoneyama M, Kikuchi M, Natsukawa T et al. The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat Immunol 2004; 5:730-7.
11. Kang D, Gopalkrishnan RV, Wu Q, Jankowsky E, Pyle AM, Fisher PB. mda-5: an interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties. Proc Natl Acad Sci USA 2002; 99:637-42.
12. Kato H, Takeuchi O, Sato S et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006; 441:101-5.
13. Hornung V, Ellegast J, Kim S et al. 5′-Triphosphate RNA is the ligand for RIG-I. Science 2006; 314:994-7.
14. Kato H, Takeuchi O, Mikamo-Satoh E et al. Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid-inducible gene-I and melanoma differentiation-associated gene 5. J Exp Med 2008; 205:1601-10.
15. Wilkins C, Gale M Jr. Recognition of viruses by cytoplasmic sensors. Curr Opin Immunol 2010; 22:41-7.
16. Ikegame S, Takeda M, Ohno S, Nakatsu Y, Nakanishi Y, Yanagi Y. Both RIG-I and MDA5 RNA helicases contribute to the induction of α/β interferon in measles virus-infected human cells. J Virol 2010; 84:372-9.
17. Gitlin L, Benoit L, Song C, Cella M, Gilfillan S, Holtzman MJ, Colonna M. Melanoma differentiation-associated gene 5 (MDA5) is involved in the innate immune response to Paramyxoviridae infection in vivo. PLoS Pathog 2010; 6:e1000734.
18. Abdullah Z, Schlee M, Roth S et al. RIG-I detects infection with live Listeria by sensing secreted bacterial nucleic acids. EMBO J 2012; 31:4153-64.
19. Chang MX, Collet B, Nie P, Lester K, Campbell S, Secombes CJ, Zou J. Expression and functional characterization of the RIG-I-like receptors MDA5 and LGP2 in rainbow trout (Oncorhynchus mykiss). J Virol 2011; 85:8403-12.
20. Driever W, Rangini Z. Characterization of a cell line derived from zebrafish (Brachydanio rerio) embryos. In Vitro Cell Dev Biol Animal 1993; 29:749-54.
21. He S, Salas-Vidal E, Rueb S, Krens SF, Meijer AH, Snaar-Jagalska BE, Spaink HP. Genetic and transcriptome characterization of model zebrafish cell lines. Zebrafish 2006; 3:441-53.
22. Pressley ME, Phelan PE, Witten PE, Mellon MT, Kim CH. Pathogenesis and inflammatory response to Edwardsiella tarda infection in the zebrafish. Dev Comp Immunol 2005; 29:501-13.
23. Lopez-Munoz A, Roca FJ, Meseguer J, Mulero V. New insights into the evolution of IFNs: zebrafish group II IFNs induce a rapid and transient expression of IFN-dependent genes and display powerful antiviral activities. J Immunol 2009; 182:3440-9.
24. Marchler-Bauer A, Lu S, Anderson JB et al. CDD: a conserved domain database for the functional annotation of proteins. Nucleic Acids Res 2011; 39:D225-9.
25. Pfaffl MW. A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 2001; 29:2002-7.
26. Chang MX, Nie P, Wei LL. Short and long peptidoglycan recognition proteins (PGRPs) in zebrafish, with findings of multiple PGRP homologs in teleost fish. Mol Immunol 2007; 44:3005-23.
27. Sun F, Zhang YB, Liu TK, Shi J, Wang B, Gui JF. Fish MITA serves as a mediator for distinct fish IFN gene activation dependent on IRF3 or IRF7. J Immunol 2011; 187:2531-9.
28. Loo YM, Fornek J, Crochet N et al. Distinct RIG-I and MDA5 signaling by RNA viruses in innate immunity. J Virol 2008; 82:335-45.
29. Gitlin L, Barchet W, Gilfillan S, Cella M, Beutler B, Flavell RA, Diamond MS, Colonna M. Essential role of MDA-5 in type I IFN responses to polyriboinosinic: polyribocytidylic acid and encephalomyocarditis picornavirus. Proc Natl Acad Sci USA 2006; 103:8459-64.
30. Fredericksen BL, Gale M Jr. West Nile virus evades activation of interferon regulatory factor 3 through RIG-I-dependent and -independent pathways without antagonizing host defense signaling. J Virol 2006; 80:2913-23.
31. Luthra P, Sun DY, Silverman RH, He BA. Activation of IFN-β expression by a viral mRNA through RNase L and MDA5. Proc Natl Acad Sci USA 2011; 108:2118-23.
32. Pichlmair A, Schulz O, Tan CP et al. Activation of MDA5 requires higher-order RNA structures generated during virus infection. J Virol 2009; 83:10761-9.
33. Takeuchi O, Akira S. MDA5/RIG-I and virus recognition. Curr Opin Immunol 2008; 20:17-22.
34. Lenz LL, Mohammadi S, Geissler A, Portnoy DA. SecA2-dependent secretion of autolytic enzymes promotes Listeria monocytogenes pathogenesis. Proc Natl Acad Sci USA 2003; 100:12432-7.
35. Zheng J, Leung KY. Dissection of a type VI secretion system in Edwardsiella tarda. Mol Microbiol 2007; 66:1192-206.
36. Tan YP, Zheng J, Tung SL, Rosenshine I, Leung KY. Role of type III secretion in Edwardsiella tarda virulence. Microbiology 2005; 151:2301-13.
37. Loo YM, Gale M Jr. Immune signaling by RIG-I-like receptors. Immunity 2011; 34:680-92.
38. Biacchesi S, LeBerre M, Lamoureux A, Louise Y, Lauret E, Boudinot P, Bremont M. Mitochondrial antiviral signaling protein plays a major role in induction of the fish innate immune response against RNA and DNA viruses. J Virol 2009; 83:7815-27.
39. Kondrashov FA, Koonin EV. Evolution of alternative splicing: deletions, insertions and origin of functional parts of proteins from intron sequences. Trends Genet 2003; 19:115-9.
40. Leung E, Hong J, Fraser A, Krissansen GW. Splicing of NOD2 (CARD15) RNA transcripts. Mol Immunol 2007; 44:284-94.
41. Rosenstiel P, Huse K, Till A et al. A short isoform of NOD2/CARD15, NOD2-S, is an endogenous inhibitor of NOD2/receptor-interacting protein kinase 2-induced signaling pathways. Proc Natl Acad Sci USA 2006; 103:3280-5.
42. Lad SP, Yang G, Scott DA, Chao TH, Correia Jda S, de la Torre JC, Li E. Identification of MAVS splicing variants that interfere with RIGI/MAVS pathway signaling. Mol Immunol 2008; 45:2277-87.