Pumpkin (Cucurbita sp.) seeds as nutraceutic: A review on status quo and scopes

Mediterranean Journal of Nutrition and Metabolism

Volumn 6, Issue 3, 2013, Pages 183-189

  Patel, Seema ^a  

^a SAN DIEGO STATE UNIVERSITY   (United States)

Author keywords

Functional food; Phytosterol; Polyunsaturated fatty acid; Prostate health; Pumpkin seed

Indexed keywords

NUTRACEUTICAL; VEGETABLE OIL;

ANTIOXIDANT ACTIVITY; BIOCHEMICAL COMPOSITION; DIABETES MELLITUS; DIET SUPPLEMENTATION; DIETARY INTAKE; FOOD ALLERGY; FUNCTIONAL FOOD; HEADACHE; HEART PROTECTION; HOT FLUSH; HUMAN; HYPERLIPIDEMIA; HYPERTENSION; NONHUMAN; NUTRIENT CONTENT; PAIN; PATIENT SAFETY; PHYTOBEZOAR; PHYTOCHEMISTRY; PLANT SEED; PRIORITY JOURNAL; PROSTATE HYPERTROPHY; REVIEW; SQUASH; STOMACH PAIN; TAENIASIS; THERAPY EFFECT;

CUCURBITA;

EID: 84891855284     PISSN: 1973798X     EISSN: 19737998     Source Type: Journal    
DOI: 10.1007/s12349-013-0131-5     Document Type: Review

References (37)

1. Stevenson DG, Eller FJ, Wang L, Jane JL, Wang T, Inglett GE (2007) Oil and tocopherol content and composition of pumpkin seed in 12 cultivars. J Agric Food Chem 55:4005-4013 (Pubitemid 46867409)
2. Ryan E, Galvin K, O'Connor TP, Maguire AR, O'Brien NM (2007) Phytosterol, squalene, tocopherol content and fatty acid profile of selected seeds, grains, and legumes. Plant Foods Hum Nutr 62:85-91 (Pubitemid 47397533)
3. Veronezi CM, Jorge N (2012) Bioactive compounds in lipid fractions of pumpkin (Cucurbita sp.) seeds for use in food. J Food Sci 77:653-657
4. Kim MY, Kim EJ, Kim YN, Choi C, Lee BH (2012) Comparison of the chemical compositions and nutritive values of various pumpkin (Cucurbitaceae) species and parts. Nutr Res Pract 6:21-27
5. Chung KH, Shin KO, Hwang HJ, Choi KS (2013) Chemical composition of nuts and seeds sold in Korea. Nutr Res Pract 7:82-88
6. Andjelkovic M, Van Camp J, Trawka A, Verhe R (2010) Phenolic compounds and some quality parameters of pumpkin seed oil. Eur J Lipid Sci Technol 112:208-217
7. Ardabili AG, Farhoosh R, Khodaparast MHH (2010) Frying stability of canola oil in presence of pumpkin seed and olive oils. Eur J Lipid Sci Technol 112:871-877
8. 4-induced liver injury in low-protein fed rats. Phytother Res 20:935-940 (Pubitemid 44763776)
9. El-Boghdady NA (2011) Protective effect of ellagic acid and pumpkin seed oil against methotrexate-induced small intestine damage in rats. Ind J Biochem Biophys 48:380-387
10. Naghii MR, Mofid M (2007) Impact of daily consumption of iron fortified ready-to-eat cereal and pumpkin seed kernels (Cucurbita pepo) on serum iron in adult women. BioFactors 30:19-26
11. Norfezah MN, Hardacre A, Brennan CS (2011) Comparison of waste pumpkin material and its potential use in extruded snack foods. Food Sci Technol Int 17:367-373
12. Radocaj O, Dimic E, Vujasinovic V (2012) Development of a hull-less pumpkin (Cucurbita pepo L.) seed oil press-cake spread. J Food Sci 77:1011-1017
13. Ward D, Ainsworth P (1998) The development of a nutritious low cost weaning food for Kenya infants. Afr J Health Sci 5:89-95 (Pubitemid 128164417)
14. El-Soukkary FA (2001) Evaluation of pumpkin seed products for bread fortification. Plant Foods Hum Nutr 56:365-384 (Pubitemid 32956306)
15. Procida G, Stancher B, Cateni F, Zacchigna M (2012) Chemical composition and functional characterisation of commercial pumpkin seed oil. J Sci Food Agric (PMID 22936573)
16. Butinar B, Bucar-Miklavcic M, Valencic V, Raspor P (2010) Stereospecific analysis of triacylglycerols as a useful means to evaluate genuineness of pumpkin seed oils: lesson from virgin olive oil analyses. J Agric Food Chem 58:5227-5234
17. Vujasinovic V, Radocaj O, Dimic E (2012) Optimization of hull-less pumpkin seed roasting conditions using response surface methodology. J Food Sci 77:532-538
18. Bowman T, Barringer S (2012) Analysis of factors affecting volatile compound formation in roasted pumpkin seeds with selected ion flow tube-mass spectrometry (SIFT-MS) and sensory analysis. J Food Sci 77:51-60
19. Makni M, Fetoui H, Gargouri NK, el Garoui M, Jaber H, Makni J, Boudawara T, Zeghal N (2008) Hypolipidemic and hepatoprotective effects of flax and pumpkin seed mixture rich in omega-3 and omega-6 fatty acids in hypercholesterolemic rats. Food Chem Toxicol 46:3714-3720
20. Gossell-Williams M, Lyttle K, Clarke T, Gardner M, Simon O (2008) Supplementation with pumpkin seed oil improves plasma lipid profile and cardiovascular outcomes of female non-ovariectomized and ovariectomized Sprague-Dawley rats. Phytother Res 22:873-877
21. Barakat LA, Mahmoud RH (2011) The antiatherogenic, renal protective and immunomodulatory effects of purslane, pumpkin and flax seeds on hypercholesterolemic rats. North Am J Med Sci 3:411-417
22. El-Mosallamy AE, Sleem AA, Abdel-Salam OM, Shaffie N, Kenawy SA (2012) Antihypertensive and cardioprotective effects of pumpkin seed oil. J Med Food 15:180-189
23. Makni M, Sefi M, Fetoui H, El Garoui M, Garouri NK, Boudawara T, Zeghal N (2010) Flax and pumpkin seeds mixture ameliorates diabetic nephropathy in rats. Food Chem Toxicol 48:2407-2412
24. Makni M, Fetoui H, Gargouri NK, El Garoui M, Zeghal N (2011) Antidiabetic effect of flax and pumpkin seed mixture powder: effect on hyperlipidemia and antioxidant status in alloxan diabetic rats. J Diabetes Complicat 25:339-345
25. Teugwa CM, Boudjeko T, Tchinda BT, Majiato PC, Zofou D (2013) Anti-hyperglycaemic globulins from selected Cucurbitaceae seeds used as antidiabetic medicinal plants in Africa. BMC Complement Altern Med 13:63
26. Gossell-Williams M, Davis A, O'Connor N (2006) Inhibition of testosterone-induced hyperplasia of the prostate of Sprague-Dawley rats by pumpkin seed oil. J Med Food 9:284-286 (Pubitemid 44036122)
27. Hong H, Kim CS, Maeng S (2009) Effects of pumpkin seed and saw palmetto oil in Korean men with symptomatic benign prostatic hyperplasia. Nutr Res Pract 3:323-327
28. Jiang J, Eliaz I, Sliva D (2011) Suppression of growth and invasive behavior of human prostate cancer cells by ProstaCaid™: mechanism of activity. Int J Oncol 38:1675-1682
29. Zaineddin AK, Buck K, Vrieling A, Heinz J, Flesch-Janys D, Linseisen J, Chang-Claude J (2012) The association between dietary lignans, phytoestrogen-rich foods, and fiber intake and postmenopausal breast cancer risk: a German case-control study. Nutr Cancer 64:652-665
30. Gossell-Williams M, Hyde C, Hunter T, Simms-Stewart D, Fletcher H, McGrowder D, Walters CA (2011) Improvement in HDL cholesterol in postmenopausal women supplemented with pumpkin seed oil: pilot study. Climacteric 14:558-564
31. Li T, Ito A, Chen X, Long C, Okamoto M, Raoul F, Giraudoux P, Yanagida T, Nakao M, Sako Y, Xiao N, Craig PS (2012) Usefulness of pumpkin seeds combined with areca nut extract in community-based treatment of human taeniasis in northwest Sichuan Province, China. Acta Trop 124:152-157
32. Mirza MS, Al-Wahibi K, Baloch S, Al-Qadhi H (2009) Rectal bezoars due to pumpkin seeds. Trop Dr 39:54-55
33. Manne JR, Rangu VM, Motapothula UM, Hall MC (2012) A crunching colon: rectal bezoar caused by pumpkin seed consumption. Clin Med Res 10:75-77
34. Rodriguez-Jimenez B, Dominguez-Ortega J, Ledesma A, Gonzalez-Garcia JM, Kindelan-Recarte C (2010) Food allergy to pumpkin seed. Allergologia et Immunopathologia (Madr) 38:50-51
35. Saucedo-Hernandez Y, Lerma-Garcia MJ, Herrero-Martinez JM, Ramis-Ramos G, Jorge-Rodriguez E, Simi-Alfonso EF (2011) Classification of pumpkin seed oils according to their species and genetic variety by attenuated total reflection Fourier-transform infrared spectroscopy. J Agric Food Chem 59:4125-4129
36. Willis C, Little CL, Sagoo S, de Pinna E, Threlfall J (2009) Assessment of the microbiological safety of edible dried seeds from retail premises in the United Kingdom with a focus on Salmonella spp. Food Microbiol 26:847-852
37. Kalogeropoulos N, Chiou A, Ioannou MS, Karathanos VT (2013) Nutritional evaluation and health promoting activities of nuts and seeds cultivated in Greece. Int J Food Sci Nutr (PMID 23641668)