Spontaneous aggregation of the insulin-derived steric zipper peptide VEALYL results in different aggregation forms with common features

Journal of Molecular Biology

Volumn 426, Issue 2, 2014, Pages 362-376

  Matthes, Dirk ^a   Daebel, Venita ^a   Meyenberg, Karsten ^b   Riedel, Dietmar ^a   Heim, Gudrun ^a   Diederichsen, Ulf ^b   Lange, Adam ^a   De Groot, Bert L ^a  

^a MAX PLANCK INSTITUTE FOR BIOPHYSICAL CHEMISTRY   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

Author keywords

amyloid; chemical shift; molecular dynamics; polymorphism; solid state NMR

Indexed keywords

AMYLOID; CARBON 13; HEXAPEPTIDE; INSULIN; PEPTIDE; STERIC ZIPPER PEPTIDE; UNCLASSIFIED DRUG; VALINE;

ARTICLE; BETA SHEET; MOLECULAR DYNAMICS; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN CONFORMATION; PROTEIN STABILITY; PROTEIN STRUCTURE; SOLID STATE;

AMINO ACID MOTIFS; AMYLOID; INSULIN; MAGNETIC RESONANCE SPECTROSCOPY; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MOLECULAR DYNAMICS SIMULATION; PEPTIDES; PROTEIN CONFORMATION; PROTEIN DENATURATION; PROTEIN MULTIMERIZATION;

EID: 84891834552     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2013.10.020     Document Type: Article

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