Unique identification of supramolecular structures in amyloid fibrils by solid-state NMR spectroscopy

Angewandte Chemie - International Edition

Volumn 48, Issue 12, 2009, Pages 2118-2121

  Nielsen, Jakob T ^a   Bjerring, Morten ^a   Jeppesen, Martin D ^a   Pedersen, Ronnie O ^a   Pedersen, Jan M ^a   Hein, Kim L ^a   Vosegaard, Thomas ^a   Skrydstrup, Troels ^a   Otzen, Daniel E ^a   Nielsen, Niels C ^a  

^a AARHUS UNIVERSITY   (Denmark)

Author keywords

Amyloid fibrils; NMR spectroscopy; Peptides; Supramolecular chemistry

Indexed keywords

AMYLOID FIBRILS; AMYLOIDOGENIC FRAGMENTS; FIBRIL STRUCTURES; HUMAN ISLETS; NMR SPECTROSCOPY; RANGE CONSTRAINTS; RESONANCE ASSIGNMENTS; SOLID-STATE NMR; SOLID-STATE NMR SPECTROSCOPIES; SUPRAMOLECULAR ORGANIZATIONS; SUPRAMOLECULAR STRUCTURES;

AMINES; GLYCOPROTEINS; MACROMOLECULES; NUCLEAR MAGNETIC RESONANCE; PEPTIDES; SELF ASSEMBLED MONOLAYERS; SOLID STATE PHYSICS; SUPRAMOLECULAR CHEMISTRY;

NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

AMYLIN; AMYLOID;

ARTICLE; CHEMISTRY; HUMAN; METHODOLOGY; NUCLEAR MAGNETIC RESONANCE; PROTEIN TERTIARY STRUCTURE; ULTRASTRUCTURE;

AMYLOID; HUMANS; ISLET AMYLOID POLYPEPTIDE; NUCLEAR MAGNETIC RESONANCE, BIOMOLECULAR; PROTEIN STRUCTURE, TERTIARY;

EID: 61949381334     PISSN: 14337851     EISSN: None     Source Type: Journal    
DOI: 10.1002/anie.200804198     Document Type: Article

References (13)

1. A. T. Petkova, R. D. Leapman, Z. H. Guo, W. M. Yau, M. P. Mattson, R. Tycko, Science 2005, 307, 262-265.
2. K. Iwata, T. Fujiwara, Y. Matsuki, H. Akutsu, S. Takahashi, H. Naiki, Y. Goto, Proc. Natl. Acad. Sci. USA 2006, 103, 18119-18124.
3. C. P. Jaroniec, C. E. MacPhee, V. S. Bajaj, M. T. McMahon, C. M. Dobson, R. G. Griffin, Proc. Natl. Acad. Sci. USA 2004, 101, 711-716.
4. C. Wasmer, A. Lange, H. Van Melckebeke, A. B. Siemer, R. Riek, B. H. Meier, Science 2008, 319, 1523-1526.
5. A. J. Geddes, K. D. Parker, E. D. T. Atkins, E. Beighton, J. Mol. Biol. 1968, 32, 343.
6. G. J. S. Cooper, A. C. Willis, A. Clark, R. C. Turner, R. B. Sim, K. B. M. Reid, Proc. Natl. Acad. Sci. USA 1987, 84, 8626-8632.
7. P. Westermark, C. Wernstedt, E. Wilander, D. W. Hayden, T. D. O'Brien, K. H. Johnson, Proc. Natl. Acad. Sci. USA 1987, 84, 3881-3885.
8. M. R. Sawaya, S. Sambashivan, R. Nelson, M. I. Ivanova, S. A. Sievers, M. I. Apostol, M. J. Thompson, M. Balbirnie, J. J. W. Wiltzius, H. T. McFarlane, A. O. Madsen, C. Riekel, D. Eisenberg, Nature 2007, 447, 453-457.
9. D. S. Wishart, B. D. Sykes, J. Biomol. NMR 1994, 4, 171-180.
10. K. Takegoshi, J. Mizokami, T. Terao, Chem. Phys. Lett. 2001, 344, 631-637.
11. M. Nilges, S. I. O'Donoghue, Prog. Nucl. Magn. Reson. Spectrosc. 1998, 32, 107-139.
12. S. Luca, Y. M. Yau, R. Leapman, R. Tycko, Biochemistry 2007, 46, 13505-13522.
13. J. Madine, E. Jack, P. G. Stockley, S. E. Radford, L. C. Serpell, D. A. Middleton, J. Am. Chem. Soc. 2008, 130, 14990-15001.