A direct-infusion-and HPLC-ESI-orbitrap-MS approach for the characterization of intact pegylated proteins

Analytical Chemistry

Volumn 86, Issue 1, 2014, Pages 826-834

  Forstenlehner, Ines C ^a   Holzmann, Johann ^a,b   Scheffler, Kai ^a,c   Wieder, Wolfgang ^b   Toll, Hansjörg ^a,b   Huber, Christian G ^a  

^a UNIVERSITY OF SALZBURG   (Austria)

^b NOVARTIS PHARMA AG   (Switzerland)

^c THERMO FISHER SCIENTIFIC   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CHROMATOGRAPHIC PEAKS; CHROMATOGRAPHIC SEPARATIONS; DECONVOLUTED MASS SPECTRA; ELECTROSPRAY IONIZATIONMASS SPECTROMETRIES (ESI-MS); GRANULOCYTE-COLONY STIMULATING FACTOR; METHIONINE OXIDATION; METHOD DEVELOPMENT; PEGYLATED PROTEINS;

AMINO ACIDS; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; ELECTROSPRAY IONIZATION; MASS SPECTROMETERS; MASS SPECTROMETRY; OXIDATION; POLYETHYLENE GLYCOLS; RECOMBINANT PROTEINS; TRIETHANOLAMINE;

HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;

COLONY STIMULATING FACTOR; MACROGOL DERIVATIVE;

ARTICLE; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; MASS SPECTROMETRY; METHODOLOGY;

CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COLONY-STIMULATING FACTORS; HUMANS; MASS SPECTROMETRY; POLYETHYLENE GLYCOLS; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 84891810603     PISSN: 00032700     EISSN: 15206882     Source Type: Journal    
DOI: 10.1021/ac403390y     Document Type: Article

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