Chemical modification and site-directed mutagenesis of methionine residues in recombinant human granulocyte colony-stimulating factor. Effect on stability and biological activity

Archives of Biochemistry and Biophysics

Volumn 362, Issue 1, 1999, Pages 1-11

  Lu, Hsieng S ^a   Fausset, Patricia R ^a   Narhi, Linda O ^a   Horan, Thomas ^a   Shinagawa, Kyoko ^b   Shimamoto, Grant ^a   Boone, Thomas C ^a  

^a AMGEN INC   (United States)

^b KIRIN BREWERY CO LTD   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

COLONY STIMULATING FACTOR RECEPTOR; HYDROGEN PEROXIDE; LEUCINE; METHIONINE; RECOMBINANT GRANULOCYTE COLONY STIMULATING FACTOR; TERT BUTYL HYDROPEROXIDE;

ARTICLE; CHEMICAL MODIFICATION; CONFORMATION; HUMAN; MOLECULAR SIZE; MOLECULAR STABILITY; OXIDATION; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS;

EID: 0033080174     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1006/abbi.1998.1022     Document Type: Article

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