Structural characterization of protein-polymer conjugates. I. Assessing heterogeneity of a small PEGylated protein and mapping conjugation sites using ion exchange chromatography and top-down tandem mass spectrometry

International Journal of Mass Spectrometry

Volumn 312, Issue , 2012, Pages 135-143

  Abzalimov, Rinat R ^a   Frimpong, Agya ^a   Kaltashov, Igor A ^a  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

Author keywords

Covalent modification; Ion exchange chromatography; Ion fragmentation, top down; Mass spectrometry; PEGylated protein; Therapeutic protein

Indexed keywords

EID: 84857056949     PISSN: 13873806     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijms.2011.06.004     Document Type: Article

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