PSTPIP2 dysregulation contributes to aberrant terminal differentiation in GATA-1-deficient megakaryocytes by activating LYN

Cell Death and Disease

Volumn 5, Issue 1, 2014, Pages

  Liu, L ^a   Wen, Q ^b   Gong, R ^c   Gilles, L ^b   Stankiewicz, M J ^b   Li, W ^a,a   Guo, M ^a   Li, L ^d   Sun, X ^d   Crispino, J D ^b   Huang, Z ^a  

^a WUHAN UNIVERSITY   (China)

^b NORTHWESTERN UNIVERSITY   (United States)

^c Hubei Entry Exit Inspection and Quarantine Bureau   (China)

^d NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

GATA 1; LYN; Megakaryopoiesis; PSTPIP2; TPO signaling

Indexed keywords

C SRC TERMINAL KINASE; DNA; FIBRINOGEN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PEST FAMILY PHOSPHATASE; PHOSPHATASE; PROTEIN KINASE LYN; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR GATA 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN K 562; CONTROLLED STUDY; DNA CONTENT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; GENE; GENE INTERACTION; GENE OVEREXPRESSION; GENE SILENCING; INTRACELLULAR SIGNALING; MEGAKARYOCYTE; MEGAKARYOPOIESIS; MOUSE; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROLINE SERINE THREONINE PHOSPHATASE INTERACTING GENE 2; UPREGULATION;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; CELL DIFFERENTIATION; CELLS, CULTURED; CYTOSKELETAL PROTEINS; DOWN-REGULATION; GATA1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION; HUMANS; K562 CELLS; MEGAKARYOCYTES; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES;

EID: 84891791450     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2013.512     Document Type: Article

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