메뉴 건너뛰기




Volumn 42, Issue 1, 2014, Pages 315-327

Human telomeres that carry an integrated copy of human herpesvirus 6 are often short and unstable, facilitating release of the viral genome from the chromosome

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; CELLULAR DISTRIBUTION; CHROMOSOME; CONTROLLED STUDY; GENE DISRUPTION; GENE SEQUENCE; GENETIC ASSOCIATION; GENOMIC INSTABILITY; GERM LINE; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 6; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; SOMATIC CELL; TELOMERE; VIRUS DNA CELL DNA INTERACTION; VIRUS GENOME; VIRUS REACTIVATION; VIRUS RELEASE; CHROMOSOME 12Q; CHROMOSOME 17P; CHROMOSOME XP; CHROMOSOME YP; INTEGRATED COPY OF HUMAN HERPESVIRUS 6; LYMPHOBLASTOID CELL LINE; MALE; SPERM; VIRUS CARRIER; VIRUS LATENCY;

EID: 84891790566     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkt840     Document Type: Article
Times cited : (67)

References (49)
  • 2
    • 0024362809 scopus 로고
    • Human telomeres contain at least 3 types of G-rich repeat distributed non-randomly
    • Allshire, R.C., Dempster, M. and Hastie, N.D. (1989) Human telomeres contain at least 3 types of G-rich repeat distributed non-randomly. Nucleic Acids Res., 17, 4611-4627.
    • (1989) Nucleic Acids Res , vol.17 , pp. 4611-4627
    • Allshire, R.C.1    Dempster, M.2    Hastie, N.D.3
  • 3
    • 0028880546 scopus 로고
    • Mechanisms underlying telomere repeat turnover, revealed by hypervariable variant repeat distribution patterns in the human Xp/Yp telomere
    • Baird, D.M., Jeffreys, A.J. and Royle, N.J. (1995) Mechanisms underlying telomere repeat turnover, revealed by hypervariable variant repeat distribution patterns in the human Xp/Yp telomere. EMBO J., 14, 5433-5443.
    • (1995) EMBO J. , vol.14 , pp. 5433-5443
    • Baird, D.M.1    Jeffreys, A.J.2    Royle, N.J.3
  • 4
    • 0033924643 scopus 로고    scopus 로고
    • High levels of sequence polymorphism and linkage disequilibrium at the telomere of 12q: Implications for telomere biology and human evolution
    • Baird, D.M., Coleman, J., Rosser, Z.H. and Royle, N.J. (2000) High levels of sequence polymorphism and linkage disequilibrium at the telomere of 12q: Implications for telomere biology and human evolution. Am. J. Hum. Genet., 66, 235-250.
    • (2000) Am. J. Hum. Genet , vol.66 , pp. 235-250
    • Baird, D.M.1    Coleman, J.2    Rosser, Z.H.3    Royle, N.J.4
  • 5
    • 0031000884 scopus 로고    scopus 로고
    • Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening
    • Makarov, V.L., Hirose, Y. and Langmore, J.P. (1997) Long G tails at both ends of human chromosomes suggest a C strand degradation mechanism for telomere shortening. Cell, 88, 657-666.
    • (1997) Cell , vol.88 , pp. 657-666
    • Makarov, V.L.1    Hirose, Y.2    Langmore, J.P.3
  • 6
    • 46249125488 scopus 로고    scopus 로고
    • How shelterin protects mammalian telomeres
    • Palm, W. and de Lange, T. (2008) How shelterin protects mammalian telomeres. Annu. Rev. Genet., 42, 301-334.
    • (2008) Annu. Rev. Genet , vol.42 , pp. 301-334
    • Palm, W.1    De Lange, T.2
  • 8
    • 84860456242 scopus 로고    scopus 로고
    • Removal of shelterin reveals the telomere end-protection problem
    • Sfeir, A. and de Lange, T. (2012) Removal of shelterin reveals the telomere end-protection problem. Science, 336, 593-597.
    • (2012) Science , vol.336 , pp. 593-597
    • Sfeir, A.1    De Lange, T.2
  • 10
    • 84555178942 scopus 로고    scopus 로고
    • Five dysfunctional telomeres predict onset of senescence in human cells
    • Kaul, Z., Cesare, A.J., Huschtscha, L.I., Neumann, A.A. and Reddel, R.R. (2012) Five dysfunctional telomeres predict onset of senescence in human cells. EMBO Rep., 13, 52-59.
    • (2012) EMBO Rep , vol.13 , pp. 52-59
    • Kaul, Z.1    Cesare, A.J.2    Huschtscha, L.I.3    Neumann, A.A.4    Reddel, R.R.5
  • 11
    • 77956574174 scopus 로고    scopus 로고
    • Review, part 1: Human herpesvirus-6-basic biology, diagnostic testing, and antiviral efficacy
    • Flamand, L., Komaroff, A.L., Arbuckle, J.H., Medveczky, P.G. and Ablashi, D.V. (2010) Review, part 1: Human herpesvirus-6-basic biology, diagnostic testing, and antiviral efficacy. J. Med. Virol., 82, 1560-1568.
    • (2010) J. Med. Virol , vol.82 , pp. 1560-1568
    • Flamand, L.1    Komaroff, A.L.2    Arbuckle, J.H.3    Medveczky, P.G.4    Ablashi, D.V.5
  • 12
    • 77956562800 scopus 로고    scopus 로고
    • Review part 2: Human herpesvirus-6 in central nervous system diseases
    • Yao, K., Crawford, J.R., Komaroff, A.L., Ablashi, D.V. and Jacobson, S. (2010) Review part 2: Human herpesvirus-6 in central nervous system diseases. J. Med. Virol., 82, 1669-1678.
    • (2010) J. Med. Virol , vol.82 , pp. 1669-1678
    • Yao, K.1    Crawford, J.R.2    Komaroff, A.L.3    Ablashi, D.V.4    Jacobson, S.5
  • 16
    • 0032872855 scopus 로고    scopus 로고
    • Human herpesvirus 6B genome sequence: Coding content and comparison with human herpesvirus 6A
    • Dominguez, G., Dambaugh, T.R., Stamey, F.R., Dewhurst, S., Inoue, N. and Pellett, P.E. (1999) Human herpesvirus 6B genome sequence: Coding content and comparison with human herpesvirus 6A. J. Virol., 73, 8040-8052.
    • (1999) J. Virol , vol.73 , pp. 8040-8052
    • Dominguez, G.1    Dambaugh, T.R.2    Stamey, F.R.3    Dewhurst, S.4    Inoue, N.5    Pellett, P.E.6
  • 18
    • 0031964229 scopus 로고    scopus 로고
    • Functional identification and analysis of cis-Acting sequences which mediate genome cleavage and packaging in human herpesvirus 6
    • Deng, H. and Dewhurst, S. (1998) Functional identification and analysis of cis-Acting sequences which mediate genome cleavage and packaging in human herpesvirus 6. J. Virol., 72, 320-329.
    • (1998) J. Virol , vol.72 , pp. 320-329
    • Deng, H.1    Dewhurst, S.2
  • 19
    • 0028832045 scopus 로고
    • Characterization of human telomeric repeat sequences from human herpesvirus 6 and relationship to replication
    • Pt 2
    • Gompels, U.A. and Macaulay, H.A. (1995) Characterization of human telomeric repeat sequences from human herpesvirus 6 and relationship to replication. J. Gen. Virol., 76(Pt 2), 451-458.
    • (1995) J. Gen. Virol , vol.76 , pp. 451-458
    • Gompels, U.A.1    Macaulay, H.A.2
  • 21
    • 0032947168 scopus 로고    scopus 로고
    • Fine mapping of an apparently targeted latent human herpesvirus type 6 integration site in chromosome band 17p13.3
    • Morris, C., Luppi, M., McDonald, M., Barozzi, P. and Torelli, G. (1999) Fine mapping of an apparently targeted latent human herpesvirus type 6 integration site in chromosome band 17p13.3. J. Med. Virol., 58, 69-75.
    • (1999) J. Med. Virol , vol.58 , pp. 69-75
    • Morris, C.1    Luppi, M.2    McDonald, M.3    Barozzi, P.4    Torelli, G.5
  • 22
    • 0033199113 scopus 로고    scopus 로고
    • Inheritance of chromosomally integrated human herpesvirus 6 DNA
    • Daibata, M., Taguchi, T., Nemoto, Y., Taguchi, H. and Miyoshi, I. (1999) Inheritance of chromosomally integrated human herpesvirus 6 DNA. Blood, 94, 1545-1549.
    • (1999) Blood , vol.94 , pp. 1545-1549
    • Daibata, M.1    Taguchi, T.2    Nemoto, Y.3    Taguchi, H.4    Miyoshi, I.5
  • 23
    • 2542439750 scopus 로고    scopus 로고
    • Human herpesvirus 6 (HHV-6) is transmitted from parent to child in an integrated form and characterization of cases with chromosomally integrated HHV-6 DNA
    • Tanaka-Taya, K., Sashihara, J., Kurahashi, H., Amo, K., Miyagawa, H., Kondo, K., Okada, S. and Yamanishi, K. (2004) Human herpesvirus 6 (HHV-6) is transmitted from parent to child in an integrated form and characterization of cases with chromosomally integrated HHV-6 DNA. J. Med. Virol., 73, 465-473.
    • (2004) J. Med. Virol , vol.73 , pp. 465-473
    • Tanaka-Taya, K.1    Sashihara, J.2    Kurahashi, H.3    Amo, K.4    Miyagawa, H.5    Kondo, K.6    Okada, S.7    Yamanishi, K.8
  • 24
    • 54749144657 scopus 로고    scopus 로고
    • Human herpesvirus 6 integrates within telomeric regions as evidenced by five different chromosomal sites
    • Nacheva, E.P., Ward, K.N., Brazma, D., Virgili, A., Howard, J., Leong, H.N. and Clark, D.A. (2008) Human herpesvirus 6 integrates within telomeric regions as evidenced by five different chromosomal sites. J. Med. Virol., 80, 1952-1958.
    • (2008) J. Med. Virol , vol.80 , pp. 1952-1958
    • Nacheva, E.P.1    Ward, K.N.2    Brazma, D.3    Virgili, A.4    Howard, J.5    Leong, H.N.6    Clark, D.A.7
  • 29
    • 0025280026 scopus 로고
    • Centre d'etude du polymorphisme humain (CEPH): Collaborative genetic mapping of the human genome
    • Dausset, J., Cann, H., Cohen, D., Lathrop, M., Lalouel, J.M. and White, R. (1990) Centre d'etude du polymorphisme humain (CEPH): Collaborative genetic mapping of the human genome. Genomics, 6, 575-577.
    • (1990) Genomics , vol.6 , pp. 575-577
    • Dausset, J.1    Cann, H.2    Cohen, D.3    Lathrop, M.4    Lalouel, J.M.5    White, R.6
  • 32
    • 0036649022 scopus 로고    scopus 로고
    • Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot
    • Jeffreys, A.J. and Neumann, R. (2002) Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot. Nat. Genet., 31, 267-271.
    • (2002) Nat. Genet , vol.31 , pp. 267-271
    • Jeffreys, A.J.1    Neumann, R.2
  • 33
    • 0037313185 scopus 로고    scopus 로고
    • Extensive allelic variation and ultrashort telomeres in senescent human cells
    • Baird, D.M., Rowson, J., Wynford-Thomas, D. and Kipling, D. (2003) Extensive allelic variation and ultrashort telomeres in senescent human cells. Nat. Genet., 33, 203-207.
    • (2003) Nat. Genet , vol.33 , pp. 203-207
    • Baird, D.M.1    Rowson, J.2    Wynford-Thomas, D.3    Kipling, D.4
  • 34
    • 42549121200 scopus 로고    scopus 로고
    • Evidence for alternative lengthening of telomeres in liposarcomas in the absence of ALT-Associated PML bodies
    • Jeyapalan, J.N., Mendez-Bermudez, A., Zaffaroni, N., Dubrova, Y.E. and Royle, N.J. (2008) Evidence for alternative lengthening of telomeres in liposarcomas in the absence of ALT-Associated PML bodies. Int. J. Cancer, 122, 2414-2421.
    • (2008) Int. J. Cancer , vol.122 , pp. 2414-2421
    • Jeyapalan, J.N.1    Mendez-Bermudez, A.2    Zaffaroni, N.3    Dubrova, Y.E.4    Royle, N.J.5
  • 35
    • 79960755430 scopus 로고    scopus 로고
    • Deficiency in DNA mismatch repair increases the rate of telomere shortening in normal human cells
    • Mendez-Bermudez, A. and Royle, N.J. (2011) Deficiency in DNA mismatch repair increases the rate of telomere shortening in normal human cells. Hum. Mutat., 32, 939-946.
    • (2011) Hum. Mutat , vol.32 , pp. 939-946
    • Mendez-Bermudez, A.1    Royle, N.J.2
  • 36
    • 33144456602 scopus 로고    scopus 로고
    • Structural stability and chromosomespecific telomere length is governed by cis-Acting determinants in humans
    • Britt-Compton, B., Rowson, J., Locke, M., Mackenzie, I., Kipling, D. and Baird, D.M. (2006) Structural stability and chromosomespecific telomere length is governed by cis-Acting determinants in humans. Hum. Mol. Genet., 15, 725-733.
    • (2006) Hum. Mol. Genet , vol.15 , pp. 725-733
    • Britt-Compton, B.1    Rowson, J.2    Locke, M.3    Mackenzie, I.4    Kipling, D.5    Baird, D.M.6
  • 38
    • 71149093724 scopus 로고    scopus 로고
    • How telomeres solve the end-protection problem
    • de Lange, T. (2009) How telomeres solve the end-protection problem. Science, 326, 948-952.
    • (2009) Science , vol.326 , pp. 948-952
    • De Lange, T.1
  • 41
    • 7044232011 scopus 로고    scopus 로고
    • Homologous recombination generates T-loop-sized deletions at human telomeres
    • Wang, R.C., Smogorzewska, A. and de Lange, T. (2004) Homologous recombination generates T-loop-sized deletions at human telomeres. Cell, 119, 355-368.
    • (2004) Cell , vol.119 , pp. 355-368
    • Wang, R.C.1    Smogorzewska, A.2    De Lange, T.3
  • 42
    • 65449187067 scopus 로고    scopus 로고
    • Control of telomere length by a trimming mechanism that involves generation of t-circles
    • Pickett, H.A., Cesare, A.J., Johnston, R.L., Neumann, A.A. and Reddel, R.R. (2009) Control of telomere length by a trimming mechanism that involves generation of t-circles. EMBO J., 28, 799-809.
    • (2009) EMBO J. , vol.28 , pp. 799-809
    • Pickett, H.A.1    Cesare, A.J.2    Johnston, R.L.3    Neumann, A.A.4    Reddel, R.R.5
  • 43
    • 81255209208 scopus 로고    scopus 로고
    • Normal mammalian cells negatively regulate telomere length by telomere trimming
    • Pickett, H.A., Henson, J.D., Au, A.Y., Neumann, A.A. and Reddel, R.R. (2011) Normal mammalian cells negatively regulate telomere length by telomere trimming. Hum. Mol. Genet., 20, 4684-4692.
    • (2011) Hum. Mol. Genet , vol.20 , pp. 4684-4692
    • Pickett, H.A.1    Henson, J.D.2    Au, A.Y.3    Neumann, A.A.4    Reddel, R.R.5
  • 44
    • 79952726582 scopus 로고    scopus 로고
    • Herpesvirus telomeric repeats facilitate genomic integration into host telomeres and mobilization of viral DNA during reactivation
    • Kaufer, B.B., Jarosinski, K.W. and Osterrieder, N. (2011) Herpesvirus telomeric repeats facilitate genomic integration into host telomeres and mobilization of viral DNA during reactivation. J. Exp. Med., 208, 605-615.
    • (2011) J. Exp. Med , vol.208 , pp. 605-615
    • Kaufer, B.B.1    Jarosinski, K.W.2    Osterrieder, N.3
  • 45
    • 52949098309 scopus 로고    scopus 로고
    • Human telomere structure and biology
    • Riethman, H. (2008) Human telomere structure and biology. Annu. Rev. Genomics Hum. Genet., 9, 1-19.
    • (2008) Annu. Rev. Genomics Hum. Genet , vol.9 , pp. 1-19
    • Riethman, H.1
  • 48
    • 0029778954 scopus 로고    scopus 로고
    • A novel mechanism for telomere size control in Saccharomyces cerevisiae
    • Li, B.B. and Lustig, A.J. (1996) A novel mechanism for telomere size control in Saccharomyces cerevisiae. Genes Dev., 10, 1310-1326.
    • (1996) Genes Dev , vol.10 , pp. 1310-1326
    • Li, B.B.1    Lustig, A.J.2
  • 49
    • 0242354121 scopus 로고    scopus 로고
    • Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion
    • Lustig, A.J. (2003) Clues to catastrophic telomere loss in mammals from yeast telomere rapid deletion. Nat. Rev. Genet., 4, 916-923.
    • (2003) Nat. Rev. Genet , vol.4 , pp. 916-923
    • Lustig, A.J.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.