Functional identification and analysis of cis-acting sequences which mediate genome cleavage and packaging in human herpesvirus 6

Journal of Virology

Volumn 72, Issue 1, 1998, Pages 320-329

  Deng, Hongyu ^a   Dewhurst, Stephen ^a  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PLASMID DNA; VIRUS VECTOR;

ARTICLE; DNA CONTENT; DNA REPLICATION; HERPES VIRUS; HUMAN; HUMAN CELL; HUMAN HERPESVIRUS 6; NONHUMAN; PLASMID; PRIORITY JOURNAL; VIRUS GENOME; VIRUS PARTICLE; VIRUS REPLICATION;

EID: 0031964229     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/jvi.72.1.320-329.1998     Document Type: Article

References (36)

1. Bataille, D., and A. L. Epstein. 1997. Equimolar generation of the four possible arrangements of adjacent L components in herpes simplex virus type 1 replicative intermediates. J. Virol. 71:7736-7743.
2. Benyesh-Melnick, M., F. Probstmeyer, R. McCombs, J. P. Brunschwig, and V. Vonka. 1966. Correlation between infectivity and physical virus particles in human cytomegalovirus. J. Bacteriol. 92:1555-1561.
3. Bulboaca, G. H., H. Deng, S. Dewhurst, and M. P. Calos. Telomeric sequences from human herpesvirus 6 do not mediate nuclear retention of episomal DNA in human cells. Submitted for publication.
4. Chou, J., and B. Roizman. 1985. Isomerization of herpes simplex virus 1 genome: identification of the cis-acting and recombination sites within the domain of the a sequence. Cell 41:803-811.
5. Cone, R. W., R. C. Hackman, M. L. Huang, R. A. Bowden, J. D. Meyers, M. Metcalf, J. Zeh, R. Ashley, and L. Corey. 1993. Human herpesvirus 6 in lung tissue from patients with pneumonitis after bone marrow transplantation. N. Engl. J. Med. 329:156-161.
6. Deiss, L. P., J. Chou, and N. Frenkel. 1986. Functional domains within the a sequence involved in the cleavage-packaging of herpes simplex virus DNA. J. Virol. 59:605-618.
7. Delecluse, H. J., and W. Hammerschmidt. 1993. Status of Marek's disease virus in established lymphoma cell lines: herpesvirus integration is common. J. Virol. 67:82-92.
8. Delecluse, H. J., S. Schuller, and W. Hammerschmidt. 1993. Latent Marek's disease virus can be activated from its chromosomally integrated state in herpesvirus-transformed lymphoma cells. EMBO J. 12:3277-3286.
9. Dewhurst, S., S. C. Dollard, P. E. Pellett, and T. R. Dambaugh. 1993. Identification of a lytic-phase origin of DNA replication in human herpesvirus 6B strain Z29. J. Virol. 67:7680-7683.
10. Drobyski, W. R., W. M. Dunne, E. M. Burd, K. K. Knox, R. C. Ash, M. M. Horowitz, N. Flomenberg, and D. R. Carrigan. 1993. Human herpesvirus-6 (HHV-6) infection in allogeneic bone marrow transplant recipients: evidence of a marrow-suppressive role for HHV-6 in vivo. J. Infect. Dis. 167: 735-739.
11. Frenkel, N., H. Locker, and D. A. Vlazny. 1980. Studies of defective herpes simplex viruses. Ann. N. Y. Acad. Sci. 354:347-370.
12. Gompels, U. A., J. Nicholas, G. Lawrence, M. Jones, B. J. Thomson, M. E. Martin, S. Efstathiou, M. Craxton, and H. A. Macaulay. 1995. The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution. Virology 209:29-51.
13. Hiasa, H., K. Tanaka, H. Sakai, K. Yoshida, Y. Honda, T. Komano, and G. N. Godson. 1989. Distinct functional contributions of three potential secondary structures in the phage G4 origin of complementary DNA strand synthesis. Gene 84:17-22.
14. Hirt, B. 1967. Selective extraction of polyoma DNA from infected mouse cell cultures J. Mol. Biol. 26:365-369.
15. Kishi, M., H. Harada, M. Takahashi, A. Tanaka, M. Hayashi, M. Nonoyama, S. F. Josephs, A. Buchbinder, F. Schachter, D. V. Ablashi, F. Wong-Staal, S. Z. Salahuddin, and R. C. Gallo. 1988. A repeat sequence, GGGTTA, is shared by DNA of human herpesvirus 6 and Marek's disease virus. J. Virol. 62:4824-4827.
16. Kreuzer, K. N., M. Saunders, L. J. Weislo, and H. W. Kreuzer. 1995. Recombination-dependent DNA replication stimulated by double-strand breaks in bacteriophage T4. J. Bacteriol. 177:6844-6853.
17. Longtine, M. S., S. Enomoto, S. L. Finstad, and J. Berman. 1992. Yeast telomere repeat sequence (TRS) improves circular plasmid segregation, and TRS plasmid segregation involves the RAP1 gene product. Mol. Cell. Biol. 12:1997-2009.
18. Martinez, R., R. T. Sarisky, P. C. Weber, and S. K. Weller. 1996. Herpes simplex virus type 1 alkaline nuclease is required for efficient processing of viral DNA replication intermediates. J. Virol. 70:2075-2085.
19. McCullers, J. A., F. D. Lakeman, and R. J. Whitley. 1995. Human herpesvirus 6 is associated with focal encephalitis. Clin. Infect. Dis. 21:571-576.
20. Ogura, T., J. Tanaka, S. Kamiya, H. Sato, H. Ogura, and M. Hatano. 1986. Human cytomegalovirus persistent infection in a human central nervous system cell line: production of a variant virus with different growth characteristics. J. Gen. Virol. 67:2605-2616.
21. Pfuller, R., and W. Hammerschmidt. 1996. Plasmid-like replicative intermediates of the Epstein-Barr virus lytic origin of DNA replication. J. Virol. 70:3423-3431.
22. Portes-Sentis, S., A. Sergeant, and H. Gruffat. 1997. A particular DNA structure is required for the function of a cis-actmg component of the Epstein-Barr virus OriLyt origin of replication. Nucleic Acids Res. 25:1347-1354.
23. Sarisky, R. T., and P. C. Weber. 1994. Role of anisomorphic DNA conformations in the negative regulation of a herpes simplex virus type 1 promoter. Virology 204:569-579.
24. Secchiero, P., J. Nicholas, H. Deng, T. Xiaopeng, N. van Loon, V. R. Ruvolo, Z. N. Berneman, M. S. Reitz, Jr., and S. Dewhurst. 1995. Identification of human telomeric repeat motifs at the genome termini of human herpesvirus 7: structural analysis and heterogeneity. J. Virol. 69:8041-8045.
25. Severini, A., D. G. Scraba, and D. L. Tyrrell. 1996. Branched structures in the intracellular DNA of herpes simplex virus type 1. J. Virol. 70:3169-3175.
26. Shiraki, K., T. Mukai, T. Okuno, K. Yamanishi, and M. Takahashi. 1991. Physicochemical characterization of human herpesvirus 6 infectivity. J. Gen. Virol. 72:169-172.
27. Spaete, R. R., and N. Frenkel. 1982. The herpes simplex virus amplicon: a ew eucaryotic defective-virus cloning-amplifying vector. Cell 30:295-304.
28. Takeshita, S., K. Tezuka, M. Takahashi, H. Honkawa, A. Matsuo, T. Matsuishi, and T. Hashimoto-Gotoh. 1988. Tandem gene amplification in vitro for rapid and efficient expression in animal cells. Gene 71:9-18.
29. Thomson, B. J., S. Dewhurst, and D. Gray. 1994. Structure and heterogeneity of the a sequences of human herpesvirus 6 strain variants U1102 and Z29 and identification of human telomeric repeat sequences at the genomic termini. J. Virol. 68:3007-3014.
30. Torelli, G., P. Barozzi, R. Marasca, P. Cocconcelli, E. Merelli, L. Ceccherini-Nelli, S. Ferrari, and M. Luppi. 1995. Targeted integration of human herpesvirus 6 in the p arm of chromosome 17 of human peripheral blood mononuclear cells in vivo. J. Med. Virol. 46:178-188.
31. Umene, K. 1993. Herpes simplex virus type 1 variant a sequence generated by recombination and breakage of the a sequence in defined regions, including the one involved in recombination. J. Virol. 67:5685-5691.
32. Vlazny, D. A., A. Kwong, and N. Frenkel. 1982. Site-specific cleavage/packaging of herpes simplex virus DNA and the selective maturation of nucleocapsids contaming full-length viral DNA. Proc. Natl. Acad. Sci. USA 79: 1423-1427.
33. Wohlrab, F., S. Chatterjee, and R. D. Wells. 1991. The herpes simplex virus 1 segment inversion site is specifically cleaved by a virus-induced nuclear endonuclease. Proc. Natl. Acad. Sci. USA 88:6432-6436.
34. Wohlrab, F., M. J. McLean, and R. D. Wells. 1987. The segment inversion site of herpes simplex virus type 1 adopts a novel DNA structure. J. Biol. Chem. 262:6407-6416.
35. Yamanishi, K., T. Okuno, K. Shiraki, M. Takahashi, T. Kondo, Y. Asano, and T. Kurata. 1988. Identification of human herpesvirus-6 as a causal agent for exanthem subitum. Lancet i:1065-1067.
36. Zimmermann, J., and W. Hammerschmidt. 1995. Structure and role of the terminal repeats of Epstein-Barr virus in processing and packaging of virion DNA. J. Virol. 69:3147-3155.