Regulatory effects of introduction of an exogenous FGF2 gene on other growth factor genes in a healing tendon

Wound Repair and Regeneration

Volumn 22, Issue 1, 2014, Pages 111-118

  Tang, Jin Bo ^a,b,c   Chen, Chuan Hao ^b   Zhou, You Lang ^b   McKeever, Clarie ^c   Liu, Paul Y ^c  

^a NANTONG UNIVERSITY   (China)

^b Medical Research Center for Tissue Repair and Reconstruction of Jiangsu   (China)

^c BROWN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CONNECTIVE TISSUE GROWTH FACTOR; FIBROBLAST GROWTH FACTOR 2; PARVOVIRUS VECTOR; PLATELET DERIVED GROWTH FACTOR B; SOMATOMEDIN; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CHICKEN; CONTROLLED STUDY; DOWN REGULATION; FLEXOR TENDON; GENE EXPRESSION; GENE TRANSFER; GENE VECTOR; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; TENDON INJURY; TOE; UPREGULATION; VIRAL GENE THERAPY; WOUND HEALING;

ANIMALS; AVIAN PROTEINS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CHICKENS; CONNECTIVE TISSUE GROWTH FACTOR; DEPENDOVIRUS; DOWN-REGULATION; FIBROBLAST GROWTH FACTOR 2; GENE TRANSFER TECHNIQUES; GENETIC THERAPY; GENETIC VECTORS; INSULIN-LIKE GROWTH FACTOR I; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTO-ONCOGENE PROTEINS C-SIS; REAL-TIME POLYMERASE CHAIN REACTION; TENDON INJURIES; TOES; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION; VASCULAR ENDOTHELIAL GROWTH FACTOR A; WOUND HEALING;

EID: 84891787847     PISSN: 10671927     EISSN: 1524475X     Source Type: Journal    
DOI: 10.1111/wrr.12129     Document Type: Article

References (40)

1. James R, Kesturu G, Balian G, Chhabra AB,. Tendon: biology, biomechanics, repair, growth factors, and evolving treatment options. J Hand Surg Am 2008; 33: 102-112.
2. Wu YF, Zhou YL, Mao WF, Avanessian B, Liu PY, Tang JB,. Cellular apoptosis and proliferation in the middle and late intrasynovial tendon healing periods. J Hand Surg Am 2012; 37: 209-216.
3. Branford OA, Lee DA, Bader DL, Grobbelaar AO,. The mechanics of flexor tendon adhesions. J Hand Surg Eur 2012; 37: 555-563.
4. Elliot D, Barbieri CH, Evans RB, Mass D, Tang JB,. IFSSH Flexor Tendon Committee Report 2007. J Hand Surg Eur 2007; 32: 346-356.
5. Tang JB,. Outcomes and evaluation of flexor tendon repair. Hand Clin 2013; 29: 251-259.
6. Tang JB,. Clinical outcomes associated with flexor tendon repair. Hand Clin 2005; 21: 199-210.
7. Lou J, Tu Y, Burns M, Silva MJ, Manske P,. BMP-12 gene transfer augmentation of lacerated tendon repair. J Orthop Res 2001; 19: 1199-1202.
8. Zhu B, Cao Y, Xin KQ, Wang XT, Summerhayes IC, Liu PY, et al. Tissue reactions of adenoviral, adeno-associated viral, and liposome-plasmid vectors in tendons and comparison with early-stage healing responses of injured flexor tendons. J Hand Surg Am 2006; 31: 1652-1660.
9. Wang XT, Liu PY, Xin KQ, Tang JB,. Tendon healing in vitro: bFGF gene transfer to tenocytes by adeno-associated viral vectors promotes expression of collagen genes. J Hand Surg Am 2005; 30: 1255-1261.
10. Wang XT, Liu PY, Tang JB, Mizukami H, Xin KQ, Ozawa K, et al. Tendon healing in vitro: adeno-associated virus-2 effectively transduces intrasynovial tenocytes with persistent expression of the transgene, but other serotypes do not. Plast Reconstr Surg 2007; 119: 227-234.
11. Hamada Y, Katoh S, Hibino N, Kosaka H, Hamada D, Yasui N,. Effects of monofilament nylon coated with basic fibroblast growth factor on endogenous intrasynovial flexor tendon healing. J Hand Surg Am 2006; 31: 530-540.
12. Thomopoulos S, Kim HM, Das R, Silva MJ, Sakiyama-Elbert S, Amiel D, et al. The effects of exogenous basic fibroblast growth factor on intrasynovial flexor tendon healing in a canine model. J Bone Joint Surg Am 2010; 92: 2285-2293.
13. Thomopoulos S, Das R, Sakiyama-Elbert S, Silva MJ, Charlton N, et al. bFGF and PDGF-BB for tendon repair: controlled release and biologic activity by tendon fibroblasts in vitro. Ann Biomed Eng 2010; 38: 225-234.
14. Majewski M, Betz O, Ochsner PE, Liu F, Porter RM, Evans CH,. Ex vivo adenoviral transfer of bone morphogenetic protein 12 (BMP-12) cDNA improves Achilles tendon healing in a rat model. Gene Ther 2008; 15: 1139-1146.
15. Gulotta LV, Kovacevic D, Packer JD, Ehteshami JR, Rodeo SA,. Adenoviral-mediated gene transfer of human bone morphogenetic protein-13 does not improve rotator cuff healing in a rat model. Am J Sports Med 2011; 39: 180-187.
16. Oshiro W, Lou J, Xing X, Tu Y, Manske PR,. Flexor tendon healing in the rat: a histologic and gene expression study. J Hand Surg Am 2003; 28: 814-823.
17. Chen CH, Cao Y, Wu YF, Bais AJ, Gao JS, Tang JB,. Tendon healing in vivo: gene expression and production of multiple growth factors in early tendon healing period. J Hand Surg Am 2008; 33: 1834-1842.
18. Thomopoulos S, Kim HM, Silva MJ, Ntouvali E, Manning CN, Potter R, et al. Effect of bone morphogenetic protein 2 on tendon-to-bone healing in a canine flexor tendon model. J Orthop Res 2012; 30: 1702-1709.
19. Wu YF, Zhou YL, Tang JB,. Relative contribution of tissue oedema and the presence of an A2 pulley to resistance to flexor tendon movement: an in vitro and in vivo study. J Hand Surg Eur 2012; 37: 310-315.
20. Peterson WW, Manske PR, Kain CC, Lesker PA,. Effect of flexor sheath integrity on tendon gliding: a biomechanical and histologic study. J Orthop Res 1986; 4: 458-465.
21. Fu SC, Hung LK, Lee YW, Mok TY, Chan KM,. Tendon adhesion measured by a video-assisted gliding test in a chicken model. J Hand Surg Eur 2011; 36: 40-47.
22. Fujihara Y, Koyama H, Nishiyama N, Eguchi T, Takato T,. Gene transfer of bFGF to recipient bed improves survival of ischemic skin flap. Br J Plast Surg 2005; 58: 511-517.
23. Liu PY, Tong W, Liu K, Han SH, Wang XT, Badiavas E, et al. Liposome-mediated transfer of vascular endothelial growth factor cDNA augments survival of random-pattern skin flaps in the rat. Wound Repair Regen 2004; 12: 80-85.
24. Conese M, Ascenzioni F, Boyd AC, Coutelle C, De Fino I, De Smedt S, et al. Gene and cell therapy for cystic fibrosis: from bench to bedside. J Cyst Fibros 2011; 10 (Suppl. 2): S114-128.
25. Gauglitz GG, Jeschke MG,. Combined gene and stem cell therapy for cutaneous wound healing. Mol Pharm 2011; 8: 1471-1479.
26. Brent AE, Braun T, Tabin CJ,. Genetic analysis of interactions between the somitic muscle, cartilage and tendon cell lineages during mouse development. Development 2005; 132: 515-528.
27. Brent AE, Schweitzer R, Tabin CJ,. A somitic compartment of tendon progenitors. Cell 2003; 113: 235-248.
28. Ide J, Kikukawa K, Hirose J, Iyama K, Sakamoto H, Fujimoto T, et al. The effect of a local application of fibroblast growth factor-2 on tendon-to-bone remodeling in rats with acute injury and repair of the supraspinatus tendon. J Shoulder Elbow Surg 2009; 18: 391-398.
29. Durgam SS, Stewart AA, Pondenis HC, Yates AC, Evans RB, Stewart MC,. Responses of equine tendon- and bone marrow-derived cells to monolayer expansion with fibroblast growth factor-2 and sequential culture with pulverized tendon and insulin-like growth factor-I. Am J Vet Res 2012; 73: 162-170.
30. Brent AE, Tabin CJ,. FGF acts directly on the somitic tendon progenitors through the Ets transcription factors Pea3 and Erm to regulate scleraxis expression. Development 2004; 131: 3885-3896.
31. Dy CJ, Daluiski A, Do HT, Hernandez-Soria A, Marx R, Lyman S,. The epidemiology of reoperation after flexor tendon repair. J Hand Surg Am 2012; 37: 919-924.
32. Starnes T, Saunders RJ, Means KR Jr,. Clinical outcomes of zone II flexor tendon repair depending on mechanism of injury. J Hand Surg Am 2012; 37: 2532-2540.
33. Sandow MJ, McMahon M,. Active mobilisation following single cross grasp four-strand flexor tenorrhaphy (Adelaide repair). J Hand Surg Eur. 2011; 36: 467-475.
34. Wu YF, Cao Y, Zhou YL, Tang JB,. Biomechanical comparisons of four-strand tendon repairs with double-stranded sutures: effects of different locks and suture geometry. J Hand Surg Eur 2011; 36: 34-39.
35. Le SV, Chiu S, Meineke RC, Williams P, Wongworawat MD,. Number of suture throws and its impact on the biomechanical properties of the four-strand cruciate locked flexor tendon repair with FiberWire. J Hand Surg Eur. 2012; 37: 826-831.
36. Moriya T, Larson MC, Zhao C, An KN, Amadio PC,. The effect of core suture flexor tendon repair techniques on gliding resistance during static cycle motion and load to failure: a human cadaver study. J Hand Surg Eur 2012; 37: 316-322.
37. Wang XT, Avanessian B, Ma Q, Durfee H, Tang YQ, Liu PY,. Enhancement of flap survival and changes in angiogenic gene expression after AAV2-mediated VEGF gene transfer to rat ischemic flaps. Wound Repair Regen 2011; 19: 498-504.
38. Thomopoulos S, Das R, Sakiyama-Elbert S, Silva MJ, Charlton N, Gelberman RH,. bFGF and PDGF-BB for tendon repair: controlled release and biologic activity by tendon fibroblasts in vitro. Ann Biomed Eng 2010; 38: 225-234.
39. Chen CH, Zhou YL, Wu YF, Cao Y, Gao JS, Tang JB,. Effectiveness of microRNA in down-regulation of TGF-beta gene expression in digital flexor tendons of chickens: in vitro and in vivo study. J Hand Surg Am 2009; 34: 1777-1784.
40. Thomopoulos S, Harwood FL, Silva MJ, Amiel D, Gelberman RH,. Effect of several growth factors on canine flexor tendon fibroblast proliferation and collagen synthesis in vitro. J Hand Surg Am 2005; 30: 441-447.