The effect of a local application of fibroblast growth factor-2 on tendon-to-bone remodeling in rats with acute injury and repair of the supraspinatus tendon

Journal of Shoulder and Elbow Surgery

Volumn 18, Issue 3, 2009, Pages 391-398

  Ide, Junji ^a,b   Kikukawa, Kenshi ^b   Hirose, Jun ^a,b   Iyama, Ken ichi ^b   Sakamoto, Hidetoshi ^a   Fujimoto, Toru ^b   Mizuta, Hiroshi ^a,b  

^a KUMAMOTO UNIVERSITY   (Japan)

^b KUMAMOTO UNIVERSITY HOSPITAL   (Japan)

Author keywords

fibrin sealant; fibroblast growth factor 2 (FGF 2); histological analysis; Rotator cuff repair; supraspinatus tendon; tendon to bone remodeling

Indexed keywords

FIBRIN GLUE; FIBROBLAST GROWTH FACTOR 2;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMECHANICS; BONE REMODELING; BONE STRENGTH; CONTROLLED STUDY; HISTOLOGY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SHOULDER; SUPRASPINATUS TENDON INJURY; TENDON INJURY; TENDON RECONSTRUCTION; TENDON TO BONE REMODELING;

ACUTE DISEASE; ADMINISTRATION, TOPICAL; ANIMALS; BIOMECHANICS; BIOPSY, NEEDLE; BONE REMODELING; DISEASE MODELS, ANIMAL; FIBROBLAST GROWTH FACTOR 2; FOLLOW-UP STUDIES; IMMUNOHISTOCHEMISTRY; MALE; MUSCLE, SKELETAL; ORTHOPEDIC PROCEDURES; PROBABILITY; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; ROTATOR CUFF; SENSITIVITY AND SPECIFICITY; TENDON INJURIES; TENSILE STRENGTH;

EID: 64849114551     PISSN: 10582746     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jse.2009.01.013     Document Type: Article

References (28)

1. Boileau P., Brassart N., Watkinson D.J., Carles M., Hatzidakis A.M., and Krishnan S.G. Arthroscopic repair of full-thickness tears of the supraspinatus: Does the tendon really heal?. J Bone Joint Surg Am 87 (2005) 1229-1240
2. Canalis E., Centrella M., and McCarthy T. Effects of basic fibroblast growth factor on bone formation in vitro. J Clin Invest 81 (1988) 1572-1577
3. Carpenter J.E., Thomopoulos S., Flanagan C.L., DeBano C.M., and Soslowsky L.J. Rotator cuff defect healing: A biomechanical and histologic analysis in an animal model. J Shoulder Elbow Surg 7 (1998) 599-605
4. Chan K.C., Burkhart S.S., Thiagarajan P., and Goh J.C. Optimization of stacked halfhitch knots for arthroscopic surgery. Arthroscopy 17 (2001) 752-759
5. Galatz L.M., Ball C.M., Teefey S.A., Middleton W.D., and Yamaguchi K. The outcome and repair integrity of completely arthroscopically repaired large and massive rotator cuff tears. J Bone Joint Surg Am 86 (2004) 219-224
6. Gerber C., Schneeberger A.G., Beck M., and Schlegel U. Mechanical strength of repairs of the rotator cuff. J Bone Joint Surg Br 76 (1994) 371-380
7. Gerber C., Schneeberger A.G., Perren S.M., and Nyffeler R.W. Experimental rotator cuff repair. A preliminary study. J Bone Joint Surg Am 81 (1999) 1281-1290
8. Gerber C., Fuchs B., and Hodler J. The results of repair of massive tears of the rotator cuff. J Bone Joint Surg Am 82 (2000) 505-515
9. Gospodarowicz D., Neufeld G., and Schweigerer L. Molecular and biological characterization of fibroblast growth factor, an angiogenic factor which also controls the proliferation and differentiation of mesoderm and neuroectoderm derived cells. Cell Differ 19 (1986) 1-17
10. Harryman D.T., Mack L.A., Wang K.Y., Jackins S.E., Richardson M.L., and Matsen F.A. Repairs of the rotator cuff. Correlation of functional results with integrity of the cuff. J Bone Joint Surg Am 73 (1991) 982-989
11. Huijsmans P.E., Pritchard M.P., Berghs B.M., Van Rooyen K.S., Wallace A.L., and De Beer J.F. Arthroscopic rotator cuff repair with double-row fixation. J Bone Joint Surg Am 89 (2007) 1248-1257
12. Ide J., Tokiyoshi A., Hirose J., and Mizuta H. Arthroscopic repair of traumatic combined rotator cuff tears involving the subscapularis tendon. J Bone Joint Surg Am 89 (2007) 2378-2388
13. Ishii I., Mizuta H., Sei A., Hirose J., Kudo S., and Hiraki Y. Healing of full-thickness defects of the articular cartilage in rabbits using fibroblast growth factor-2 and a fibrin sealant. J Bone Joint Surg Br 89 (2007) 693-700
14. Itoh N., and Ornitz D.M. Evolution of the Fgf and Fgfr gene families. Trends Genet 20 (2004) 563-569
15. Kato T., Kawaguchi H., Hanada K., Aoyama I., Hiyama Y., Nakamura T., et al. Single local injection of recombinant fibroblast growth factor-2 stimulates healing of segmental bone defects in rabbits. J Orthop Res 16 (1998) 654-659
16. Koike Y., Trudel G., and Uhthoff H.K. Formation of a new enthesis after attachment of the supraspinatus tendon: A quantitative histologic study in rabbits. J Orthop Res 23 (2005) 1433-1440
17. Lieberman J.R., Daluiski A., and Einhorn T.A. The role of growth factors in the repair of bone biology and clinical applications. J Bone Joint Surg Am 84 (2002) 1032-1044
18. Murray D.H., Kubiak E.N., Jazrawi L.M., Araghi A., Kummer F., Loebenberg M.I., et al. The effect of cartilage-derived morphogenetic protein 2 on initial healing of a rotator cuff defect in a rat model. J Shoulder Elbow Surg 16 (2007) 251-254
19. Nakamura T., Hanada K., Tamura M., Shibanushi T., Nigi H., Tagawa M., et al. Stimulation of endosteal bone formation by systemic injections of recombinant basic fibroblast growth factor in rats. Endocrinology 136 (1995) 1276-1284
20. Nakamura K., Kurokawa T., Kato T., Okazaki H., Mamada K., Hanada K., et al. Local application of basic fibroblast growth factor into the bone increases bone mass at the applied site in rabbits. Arch Orthop Trauma Surg 115 (1996) 344-346
21. Otsuka Y., Mizuta H., Takagi K., Iyama K., Yoshitake Y., Nishikawa K., et al. Requirement of fibroblast growth factor signaling for regeneration of epiphyseal morphology in rabbit full-thickness defects of articular cartilage. Dev Growth Differ 39 (1997) 143-156
22. Rodeo S.A., Potter H.G., Kawamura S., Turner A.S., Kim H.J., and Atkinson B.L. Biologic augmentation of rotator cuff tendon-healing with use of a mixture of osteoinductive growth factors. J Bone Joint Surg Am 89 (2007) 2485-2497
23. Soslowsky L.J., Carpenter J.E., DeBano C.M., Banerji I., and Moalli M.R. Development and use of an animal model for investigations on rotator cuff disease. J Shoulder Elbow Surg 5 (1996) 383-392
24. Soslowsky L.J., Thomopoulos S., Tun S., Flanagan C.L., Keefer C.C., Mastaw J., et al. Overuse activity injures the supraspinatus tendon in an animal model: A histologic and biomechanical study. J Shoulder Elbow Surg 9 (2000) 79-84
25. Thomopoulos S., Soslowsky L.J., Flanagan C.L., Tun S., Keefer C.C., Mastaw J., et al. The effect of fibrin clot on healing rat supraspinatus tendon defects. J Shoulder Elbow Surg 11 (2002) 239-247
26. Thomopoulos S., Hattersley G.V., Mertens R.M., Galatz L., Williams G.R., and Soslowsky L.J. The localized expression of extracellular matrix components in healing tendon insertion sites: An in situ hybridization study. J Orthop Res 20 (2002) 454-463
27. Watkins J.P., Auer J.A., Gay S., and Morgan S.J. Healing of surgically created defects in the equine superficial digital flexor tendon: collagen-type transformation and tissue morphologic reorganization. Am J Vet Res 46 (1985) 2091-2096
28. Woo S.L.Y., An K.N., Arnoczky S.P., Wayne J.S., Fithian D.C., and Myers B.S. Anatomy, biology, and biomechanics of tendon, ligament. and meniscus. In: Simon S.R. (Ed). Orthopaedic basic science (1994), American Academy of Orthopaedic Surgeons, Rosemont, IL 45-87