메뉴 건너뛰기




Volumn 32, Issue 1, 2014, Pages 290-300

TLR ligands stimulation protects MSC from NK killing

Author keywords

Immunotolerance; Mesenchymal stem cells; NK cells; NKG2D ligands; TLR

Indexed keywords

MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8;

EID: 84891756200     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1563     Document Type: Article
Times cited : (66)

References (46)
  • 2
    • 50249158511 scopus 로고    scopus 로고
    • Mesenchymal stem cells in health and disease
    • Uccelli A, Moretta L, Pistoia V. Mesenchymal stem cells in health and disease. Nat Rev Immunol 2008;8:726-736.
    • (2008) Nat Rev Immunol , vol.8 , pp. 726-736
    • Uccelli, A.1    Moretta, L.2    Pistoia, V.3
  • 3
    • 2342482526 scopus 로고    scopus 로고
    • Treatment of severe acute graft-versushost disease with third party haploidentical mesenchymal stem cells
    • Le Blanc K, Rasmusson I, Sundberg B et al. Treatment of severe acute graft-versushost disease with third party haploidentical mesenchymal stem cells. Lancet 2004;363: 1439-1441.
    • (2004) Lancet , vol.363 , pp. 1439-1441
    • Le Blanc, K.1    Rasmusson, I.2    Sundberg, B.3
  • 4
    • 0141484485 scopus 로고    scopus 로고
    • HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells
    • Le Blanc K, Tammik C, Rosendahl K et al. HLA expression and immunologic properties of differentiated and undifferentiated mesenchymal stem cells. Exp Hematol 2003;31: 890-896.
    • (2003) Exp Hematol , vol.31 , pp. 890-896
    • Le Blanc, K.1    Tammik, C.2    Rosendahl, K.3
  • 5
    • 33744913533 scopus 로고    scopus 로고
    • Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease
    • Ringden O, Uzunel M, Rasmusson I et al. Mesenchymal stem cells for treatment of therapy-resistant graft-versus-host disease. Transplantation 2006;81:1390-1397.
    • (2006) Transplantation , vol.81 , pp. 1390-1397
    • Ringden, O.1    Uzunel, M.2    Rasmusson, I.3
  • 6
    • 27744541175 scopus 로고    scopus 로고
    • Interaction between human NK cells and bone marrow stromal cells induces NK cell triggering: Role of NKp30 and NKG2D receptors
    • Poggi A, Prevosto C, Massaro AM et al. Interaction between human NK cells and bone marrow stromal cells induces NK cell triggering: Role of NKp30 and NKG2D receptors. J Immunol 2005;175:6352-6360.
    • (2005) J Immunol , vol.175 , pp. 6352-6360
    • Poggi, A.1    Prevosto, C.2    Massaro, A.M.3
  • 7
    • 32644438233 scopus 로고    scopus 로고
    • Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NKcell proliferation
    • Spaggiari GM, Capobianco A, Becchetti S et al. Mesenchymal stem cell-natural killer cell interactions: Evidence that activated NK cells are capable of killing MSCs, whereas MSCs can inhibit IL-2-induced NKcell proliferation. Blood 2006;107:1484-1490.
    • (2006) Blood , vol.107 , pp. 1484-1490
    • Spaggiari, G.M.1    Capobianco, A.2    Becchetti, S.3
  • 8
    • 9444249908 scopus 로고    scopus 로고
    • Natural killer cell signaling pathways
    • Vivier E, Nunes JA, Vely F. Natural killer cell signaling pathways. Science 2004;306: 1517-1519.
    • (2004) Science , vol.306 , pp. 1517-1519
    • Vivier, E.1    Nunes, J.A.2    Vely, F.3
  • 9
    • 0035496603 scopus 로고    scopus 로고
    • Natural killer cells, viruses and cancer
    • Cerwenka A, Lanier LL. Natural killer cells, viruses and cancer. Nat Rev Immunol 2001;1:41-49.
    • (2001) Nat Rev Immunol , vol.1 , pp. 41-49
    • Cerwenka, A.1    Lanier, L.L.2
  • 10
    • 0025300414 scopus 로고
    • In search of the 'missing self': MHC molecules and NK cell recognition
    • Ljunggren HG, Karre K. In search of the 'missing self': MHC molecules and NK cell recognition. Immunol Today 1990;11:237-244.
    • (1990) Immunol Today , vol.11 , pp. 237-244
    • Ljunggren, H.G.1    Karre, K.2
  • 11
    • 38949183675 scopus 로고    scopus 로고
    • Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: Role of indoleamine 2,3-dioxygenase and prostaglandin E2
    • Spaggiari GM, Capobianco A, Abdelrazik H et al. Mesenchymal stem cells inhibit natural killer-cell proliferation, cytotoxicity, and cytokine production: Role of indoleamine 2,3-dioxygenase and prostaglandin E2. Blood 2008;111:1327-1333.
    • (2008) Blood , vol.111 , pp. 1327-1333
    • Spaggiari, G.M.1    Capobianco, A.2    Abdelrazik, H.3
  • 12
    • 53549124398 scopus 로고    scopus 로고
    • NKG2D ligands in tumor immunity
    • Nausch N, Cerwenka A. NKG2D ligands in tumor immunity. Oncogene 2008;27:5944-5958.
    • (2008) Oncogene , vol.27 , pp. 5944-5958
    • Nausch, N.1    Cerwenka, A.2
  • 13
    • 41549105367 scopus 로고    scopus 로고
    • Human mesenchymal stem cells stimulated by TNF-alpha, LPS, or hypoxia produce growth factors by an Nf Kappa B-but not JNK-dependent Mechanism
    • Crisostomo PR, Wang Y, Markel TA et al. Human mesenchymal stem cells stimulated by TNF-alpha, LPS, or hypoxia produce growth factors by an Nf Kappa B-but not JNK-dependent Mechanism. Am J Physiol Cell Physiol 2008;294:C675-682.
    • (2008) Am J Physiol Cell Physiol , vol.294
    • Crisostomo, P.R.1    Wang, Y.2    Markel, T.A.3
  • 14
    • 77954551154 scopus 로고    scopus 로고
    • Modulation of adult mesenchymal stem cells activity by tolllike receptors: Implications on therapeutic potential
    • DelaRosa O, Lombardo E. Modulation of adult mesenchymal stem cells activity by tolllike receptors: Implications on therapeutic potential. Mediators Inflamm 2010;2010: 865601.
    • (2010) Mediators Inflamm , vol.2010 , pp. 865601
    • Delarosa, O.1    Lombardo, E.2
  • 15
    • 38349060182 scopus 로고    scopus 로고
    • Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling
    • Liotta F, Angeli R, Cosmi L et al. Toll-like receptors 3 and 4 are expressed by human bone marrow-derived mesenchymal stem cells and can inhibit their T-cell modulatory activity by impairing Notch signaling. Stem Cells 2008;26:279-289.
    • (2008) Stem Cells , vol.26 , pp. 279-289
    • Liotta, F.1    Angeli, R.2    Cosmi, L.3
  • 16
    • 80051670366 scopus 로고    scopus 로고
    • The source of human mesenchymal stromal cells influences their TLR profile as well as their functional properties
    • Raicevic G, Najar M, Stamatopoulos B et al. The source of human mesenchymal stromal cells influences their TLR profile as well as their functional properties. Cell Immunol 2011;270:207-216.
    • (2011) Cell Immunol , vol.270 , pp. 207-216
    • Raicevic, G.1    Najar, M.2    Stamatopoulos, B.3
  • 17
    • 67649209791 scopus 로고    scopus 로고
    • Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype
    • Romieu-Mourez R, Francois M, Boivin MN et al. Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype. J Immunol 2009;182:7963-7973.
    • (2009) J Immunol , vol.182 , pp. 7963-7973
    • Romieu-Mourez, R.1    Francois, M.2    Boivin, M.N.3
  • 18
    • 77956420421 scopus 로고    scopus 로고
    • A new mesenchymal stem cell (MSC) paradigm: Polarization into a proinflammatory MSC1 or an immunosuppressive MSC2 phenotype
    • Waterman RS, Tomchuck SL, Henkle SL et al. A new mesenchymal stem cell (MSC) paradigm: Polarization into a proinflammatory MSC1 or an immunosuppressive MSC2 phenotype. PLoS One 2010;5: e10088.
    • (2010) PLoS One , vol.5
    • Waterman, R.S.1    Tomchuck, S.L.2    Henkle, S.L.3
  • 19
    • 0035524488 scopus 로고    scopus 로고
    • Toll-like receptors and innate immunity
    • Medzhitov R. Toll-like receptors and innate immunity. Nat Rev Immunol 2001;1: 135-145.
    • (2001) Nat Rev Immunol , vol.1 , pp. 135-145
    • Medzhitov, R.1
  • 20
  • 21
    • 20344389060 scopus 로고    scopus 로고
    • Toll-like receptors: Linking innate and adaptive immunity
    • Pasare C, Medzhitov R. Toll-like receptors: Linking innate and adaptive immunity. Adv Exp Med Biol 2005;560:11-18.
    • (2005) Adv Exp Med Biol , vol.560 , pp. 11-18
    • Pasare, C.1    Medzhitov, R.2
  • 22
    • 0037974914 scopus 로고    scopus 로고
    • Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection
    • Goldstein DR, Tesar BM, Akira S et al. Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection. J Clin Invest 2003;111:1571-1578.
    • (2003) J Clin Invest , vol.111 , pp. 1571-1578
    • Goldstein, D.R.1    Tesar, B.M.2    Akira, S.3
  • 23
    • 33644615635 scopus 로고    scopus 로고
    • The role of tolllike receptors in solid organ transplantation
    • Obhrai J, Goldstein DR. The role of tolllike receptors in solid organ transplantation. Transplantation 2006;81:497-502.
    • (2006) Transplantation , vol.81 , pp. 497-502
    • Obhrai, J.1    Goldstein, D.R.2
  • 24
    • 70350453471 scopus 로고    scopus 로고
    • Toll-like receptor triggering in cord blood mesenchymal stem cells
    • van den Berk LC, Jansen BJ, Siebers-Vermeulen KG et al. Toll-like receptor triggering in cord blood mesenchymal stem cells. J Cell Mol Med 2009;13:3415-3426.
    • (2009) J Cell Mol Med , vol.13 , pp. 3415-3426
    • Van Den Berk, L.C.1    Jansen, B.J.2    Siebers-Vermeulen, K.G.3
  • 25
    • 65649089411 scopus 로고    scopus 로고
    • Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R
    • Opitz CA, Litzenburger UM, Lutz C et al. Toll-like receptor engagement enhances the immunosuppressive properties of human bone marrow-derived mesenchymal stem cells by inducing indoleamine-2,3-dioxygenase-1 via interferon-beta and protein kinase R. Stem Cells 2009;27:909-919.
    • (2009) Stem Cells , vol.27 , pp. 909-919
    • Opitz, C.A.1    Litzenburger, U.M.2    Lutz, C.3
  • 26
    • 33645648586 scopus 로고    scopus 로고
    • The changing role of natural killer cells in solid organ rejection and tolerance
    • Kitchens WH, Uehara S, Chase CM et al. The changing role of natural killer cells in solid organ rejection and tolerance. Transplantation 2006;81:811-817.
    • (2006) Transplantation , vol.81 , pp. 811-817
    • Kitchens, W.H.1    Uehara, S.2    Chase, C.M.3
  • 27
    • 0037086131 scopus 로고    scopus 로고
    • Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants
    • Ruggeri L, Capanni M, Urbani E et al. Effectiveness of donor natural killer cell alloreactivity in mismatched hematopoietic transplants. Science 2002;295:2097-2100.
    • (2002) Science , vol.295 , pp. 2097-2100
    • Ruggeri, L.1    Capanni, M.2    Urbani, E.3
  • 28
    • 80053217109 scopus 로고    scopus 로고
    • Human mesenchymal stem cells derived from induced pluripotent stem cells down-regulate NK-cell cytolytic machinery
    • Giuliani M, Oudrhiri N, Noman ZM et al. Human mesenchymal stem cells derived from induced pluripotent stem cells down-regulate NK-cell cytolytic machinery. Blood 2011;118: 3254-3262.
    • (2011) Blood , vol.118 , pp. 3254-3262
    • Giuliani, M.1    Oudrhiri, N.2    Noman, Z.M.3
  • 29
    • 39149141866 scopus 로고    scopus 로고
    • Derivation and immunological characterization of mesenchymal stromal cells from human embryonic stem cells
    • Trivedi P, Hematti P. Derivation and immunological characterization of mesenchymal stromal cells from human embryonic stem cells. Exp Hematol 2008;36:350-359.
    • (2008) Exp Hematol , vol.36 , pp. 350-359
    • Trivedi, P.1    Hematti, P.2
  • 30
    • 62549157393 scopus 로고    scopus 로고
    • Brief report-Human embryonic stem cell-derived mesenchymal progenitors (EMPs) possess strong immunosuppressive effects towards natural killer cells as well as T lymphocytes
    • Yen BL, Chang CJ, Liu KJ et al. Brief report-Human embryonic stem cell-derived mesenchymal progenitors (EMPs) possess strong immunosuppressive effects towards natural killer cells as well as T lymphocytes. Stem Cells 2009;27:451-456.
    • (2009) Stem Cells , vol.27 , pp. 451-456
    • Yen, B.L.1    Chang, C.J.2    Liu, K.J.3
  • 31
    • 0033007567 scopus 로고    scopus 로고
    • Regulation of immune responses through inhibitory receptors
    • Long EO. Regulation of immune responses through inhibitory receptors. Annu Rev Immunol 1999;17:875-904.
    • (1999) Annu Rev Immunol , vol.17 , pp. 875-904
    • Long, E.O.1
  • 32
    • 0035059950 scopus 로고    scopus 로고
    • Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis
    • Moretta A, Bottino C, Vitale M et al. Activating receptors and coreceptors involved in human natural killer cell-mediated cytolysis. Annu Rev Immunol 2001;19:197-223.
    • (2001) Annu Rev Immunol , vol.19 , pp. 197-223
    • Moretta, A.1    Bottino, C.2    Vitale, M.3
  • 33
    • 0033618504 scopus 로고    scopus 로고
    • Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA
    • Bauer S, Groh V, Wu J et al. Activation of NK cells and T cells by NKG2D, a receptor for stress-inducible MICA. Science 1999;285: 727-729.
    • (1999) Science , vol.285 , pp. 727-729
    • Bauer, S.1    Groh, V.2    Wu, J.3
  • 34
    • 0035099068 scopus 로고    scopus 로고
    • ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor
    • Cosman D, Mullberg J, Sutherland CL et al. ULBPs, novel MHC class I-related molecules, bind to CMV glycoprotein UL16 and stimulate NK cytotoxicity through the NKG2D receptor. Immunity 2001;14:123-133.
    • (2001) Immunity , vol.14 , pp. 123-133
    • Cosman, D.1    Mullberg, J.2    Sutherland, C.L.3
  • 35
    • 0035054469 scopus 로고    scopus 로고
    • Role of NKG2D in tumor cell lysis mediated by human NK cells: Cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin
    • Pende D, Cantoni C, Rivera P et al. Role of NKG2D in tumor cell lysis mediated by human NK cells: Cooperation with natural cytotoxicity receptors and capability of recognizing tumors of nonepithelial origin. Eur J Immunol 2001;31:1076-1086.
    • (2001) Eur J Immunol , vol.31 , pp. 1076-1086
    • Pende, D.1    Cantoni, C.2    Rivera, P.3
  • 36
    • 0037080348 scopus 로고    scopus 로고
    • UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells
    • Sutherland CL, Chalupny NJ, Schooley K et al. UL16-binding proteins, novel MHC class I-related proteins, bind to NKG2D and activate multiple signaling pathways in primary NK cells. J Immunol 2002;168:671-679.
    • (2002) J Immunol , vol.168 , pp. 671-679
    • Sutherland, C.L.1    Chalupny, N.J.2    Schooley, K.3
  • 37
    • 0037126310 scopus 로고    scopus 로고
    • Tumourderived soluble MIC ligands impair expression of NKG2D and T-cell activation
    • Groh V, Wu J, Yee C et al. Tumourderived soluble MIC ligands impair expression of NKG2D and T-cell activation. Nature 2002; 419:734-738.
    • (2002) Nature , vol.419 , pp. 734-738
    • Groh, V.1    Wu, J.2    Yee, C.3
  • 38
    • 0037108517 scopus 로고    scopus 로고
    • Cutting edge: Down-regulation of MICA on human tumors by proteolytic shedding
    • Salih HR, Rammensee HG, Steinle A. Cutting edge: Down-regulation of MICA on human tumors by proteolytic shedding. J Immunol 2002;169:4098-4102.
    • (2002) J Immunol , vol.169 , pp. 4098-4102
    • Salih, H.R.1    Rammensee, H.G.2    Steinle, A.3
  • 39
    • 77953642977 scopus 로고    scopus 로고
    • Multiple mechanisms downstream of TLR-4 stimulation allow expression of NKG2D ligands to facilitate macrophage/NK cell crosstalk
    • Eissmann P, Evans JH, Mehrabi M et al. Multiple mechanisms downstream of TLR-4 stimulation allow expression of NKG2D ligands to facilitate macrophage/NK cell crosstalk. J Immunol 2010;184:6901-6909.
    • (2010) J Immunol , vol.184 , pp. 6901-6909
    • Eissmann, P.1    Evans, J.H.2    Mehrabi, M.3
  • 40
    • 0842278645 scopus 로고    scopus 로고
    • Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor
    • Hamerman JA, Ogasawara K, Lanier LL. Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor. J Immunol 2004;172:2001-2005.
    • (2004) J Immunol , vol.172 , pp. 2001-2005
    • Hamerman, J.A.1    Ogasawara, K.2    Lanier, L.L.3
  • 41
    • 58149190441 scopus 로고    scopus 로고
    • Interaction of monocytes with NK cells upon Tolllike receptor-induced expression of the NKG2D ligand MICA
    • Kloss M, Decker P, Baltz KM et al. Interaction of monocytes with NK cells upon Tolllike receptor-induced expression of the NKG2D ligand MICA. J Immunol 2008;181: 6711-6719.
    • (2008) J Immunol , vol.181 , pp. 6711-6719
    • Kloss, M.1    Decker, P.2    Baltz, K.M.3
  • 42
    • 33947608679 scopus 로고    scopus 로고
    • Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses
    • Nedvetzki S, Sowinski S, Eagle RA et al. Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses. Blood 2007;109: 3776-3785.
    • (2007) Blood , vol.109 , pp. 3776-3785
    • Nedvetzki, S.1    Sowinski, S.2    Eagle, R.A.3
  • 43
    • 33947179887 scopus 로고    scopus 로고
    • TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance
    • He W, Liu Q, Wang L et al. TLR4 signaling promotes immune escape of human lung cancer cells by inducing immunosuppressive cytokines and apoptosis resistance. Mol Immunol 2007;44:2850-2859.
    • (2007) Mol Immunol , vol.44 , pp. 2850-2859
    • He, W.1    Liu, Q.2    Wang, L.3
  • 44
    • 20444432334 scopus 로고    scopus 로고
    • Toll-like receptors on tumor cells facilitate evasion of immune surveillance
    • Huang B, Zhao J, Li H et al. Toll-like receptors on tumor cells facilitate evasion of immune surveillance. Cancer Res 2005;65: 5009-5014.
    • (2005) Cancer Res , vol.65 , pp. 5009-5014
    • Huang, B.1    Zhao, J.2    Li, H.3
  • 45
    • 66149140644 scopus 로고    scopus 로고
    • Triggering of Toll-like receptor 4 expressed on human head and neck squamous cell carcinoma promotes tumor development and protects the tumor from immune attack
    • Szczepanski MJ, Czystowska M, Szajnik M et al. Triggering of Toll-like receptor 4 expressed on human head and neck squamous cell carcinoma promotes tumor development and protects the tumor from immune attack. Cancer Res 2009;69:3105-3113.
    • (2009) Cancer Res , vol.69 , pp. 3105-3113
    • Szczepanski, M.J.1    Czystowska, M.2    Szajnik, M.3
  • 46
    • 38349053355 scopus 로고    scopus 로고
    • Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD41CD25high FOXP31 regulatory T cells
    • Selmani Z, Naji A, Zidi I et al. Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD41CD25high FOXP31 regulatory T cells. Stem Cells 2008;26:212-222.
    • (2008) Stem Cells , vol.26 , pp. 212-222
    • Selmani, Z.1    Naji, A.2    Zidi, I.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.