메뉴 건너뛰기




Volumn 88, Issue 2, 2014, Pages 878-889

Inhibition of arenavirus by A3, a pyrimidine biosynthesis inhibitor

Author keywords

[No Author keywords available]

Indexed keywords

A 3; ANTIVIRUS AGENT; RIBAVIRIN; UNCLASSIFIED DRUG; VIRUS RNA;

EID: 84891697312     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.02275-13     Document Type: Article
Times cited : (47)

References (58)
  • 1
    • 38349111339 scopus 로고    scopus 로고
    • Arenaviridae: the viruses and their replication
    • Fields BN, Knipe DM, Howley PM (ed), 5th ed, Lippincott Williams&Wilkins, Philadelphia, PA
    • Buchmeier MJ, Peters CJ, de la Torre JC. 2007. Arenaviridae: the viruses and their replication, p 1792-1827. In Fields BN, Knipe DM, Howley PM (ed), Fields virology, 5th ed, vol 2. Lippincott Williams&Wilkins, Philadelphia, PA.
    • (2007) Fields virology , vol.2 , pp. 1792-1827
    • Buchmeier, M.J.1    Peters, C.J.2    de la Torre, J.C.3
  • 2
    • 40749124935 scopus 로고    scopus 로고
    • Cell entry by human pathogenic arenaviruses
    • Rojek JM, Kunz S. 2008. Cell entry by human pathogenic arenaviruses. Cell. Microbiol. 10:828-835. http://dx.doi.org/10.1111/j.1462-5822.2007.01113.x.
    • (2008) Cell. Microbiol. , vol.10 , pp. 828-835
    • Rojek, J.M.1    Kunz, S.2
  • 3
    • 0242331609 scopus 로고    scopus 로고
    • The small RING finger protein Z drives arenavirus budding: implications for antiviral strategies
    • Perez M, Craven RC, de la Torre JC. 2003. The small RING finger protein Z drives arenavirus budding: implications for antiviral strategies. Proc. Natl. Acad. Sci. U. S. A. 100:12978-12983. http://dx.doi.org/10.1073/pnas.2133782100.
    • (2003) Proc. Natl. Acad. Sci. U. S. A. , vol.100 , pp. 12978-12983
    • Perez, M.1    Craven, R.C.2    de la Torre, J.C.3
  • 4
    • 0037699174 scopus 로고    scopus 로고
    • NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs
    • Lee KJ, Novella IS, Teng MN, Oldstone MB, de La Torre JC. 2000. NP and L proteins of lymphocytic choriomeningitis virus (LCMV) are sufficient for efficient transcription and replication of LCMV genomic RNA analogs. J. Virol. 74:3470-3477. http://dx.doi.org/10.1128/JVI.74.8.3470-3477.2000.
    • (2000) J. Virol. , vol.74 , pp. 3470-3477
    • Lee, K.J.1    Novella, I.S.2    Teng, M.N.3    Oldstone, M.B.4    de La Torre, J.C.5
  • 5
    • 33748480132 scopus 로고    scopus 로고
    • Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus
    • Martinez-Sobrido L, Zuniga EI, Rosario D, Garcia-Sastre A, de la Torre JC. 2006. Inhibition of the type I interferon response by the nucleoprotein of the prototypic arenavirus lymphocytic choriomeningitis virus. J. Virol. 80:9192-9199. http://dx.doi.org/10.1128/JVI.00555-06.
    • (2006) J. Virol. , vol.80 , pp. 9192-9199
    • Martinez-Sobrido, L.1    Zuniga, E.I.2    Rosario, D.3    Garcia-Sastre, A.4    de la Torre, J.C.5
  • 6
    • 36048934428 scopus 로고    scopus 로고
    • Differential inhibition of type I interferon induction by arenavirus nucleoproteins
    • Martinez-Sobrido L, Giannakas P, Cubitt B, Garcia-Sastre A, de la Torre JC. 2007. Differential inhibition of type I interferon induction by arenavirus nucleoproteins. J. Virol. 81:12696-12703. http://dx.doi.org/10.1128/JVI.00882-07.
    • (2007) J. Virol. , vol.81 , pp. 12696-12703
    • Martinez-Sobrido, L.1    Giannakas, P.2    Cubitt, B.3    Garcia-Sastre, A.4    de la Torre, J.C.5
  • 8
    • 80655125475 scopus 로고    scopus 로고
    • Lassa virus nucleoprotein mutants generated by reverse genetics induce a robust type I interferon response in human dendritic cells and macrophages
    • Carnec X, Baize S, Reynard S, Diancourt L, Caro V, Tordo N, Bouloy M. 2011. Lassa virus nucleoprotein mutants generated by reverse genetics induce a robust type I interferon response in human dendritic cells and macrophages. J. Virol. 85:12093-12097. http://dx.doi.org/10.1128/JVI.00429-11.
    • (2011) J. Virol. , vol.85 , pp. 12093-12097
    • Carnec, X.1    Baize, S.2    Reynard, S.3    Diancourt, L.4    Caro, V.5    Tordo, N.6    Bouloy, M.7
  • 9
    • 0036186216 scopus 로고    scopus 로고
    • Lassa fever
    • Oldstone MB (ed), Springer-Verlag, Berlin, Germany
    • McCormick JB, Fisher-Hoch SP. 2002. Lassa fever, p 75-110. In Oldstone MB (ed), Arenaviruses I, vol 262. Springer-Verlag, Berlin, Germany.
    • (2002) Arenaviruses I , vol.262 , pp. 75-110
    • McCormick, J.B.1    Fisher-Hoch, S.P.2
  • 11
    • 40749147093 scopus 로고    scopus 로고
    • Treatment of Argentine hemorrhagic fever
    • Enria DA, Briggiler AM, Sanchez Z. 2008. Treatment of Argentine hemorrhagic fever. Antiviral Res. 78:132-139. http://dx.doi.org/10.1016/j.antiviral.2007.10.010.
    • (2008) Antiviral Res. , vol.78 , pp. 132-139
    • Enria, D.A.1    Briggiler, A.M.2    Sanchez, Z.3
  • 12
    • 0035889456 scopus 로고    scopus 로고
    • Viral hemorrhagic fever hazards for travelers in Africa
    • Isaacson M. 2001. Viral hemorrhagic fever hazards for travelers in Africa. Clin. Infect. Dis. 33:1707-1712. http://dx.doi.org/10.1086/322620.
    • (2001) Clin. Infect. Dis. , vol.33 , pp. 1707-1712
    • Isaacson, M.1
  • 14
    • 0033829823 scopus 로고    scopus 로고
    • Lymphocytic choriomeningitis virus: an underdiagnosed cause of congenital chorioretinitis
    • Mets MB, Barton LL, Khan AS, Ksiazek TG. 2000. Lymphocytic choriomeningitis virus: an underdiagnosed cause of congenital chorioretinitis. Am. J. Ophthalmol. 130:209-215. http://dx.doi.org/10.1016/S0002-9394(00)00570-5.
    • (2000) Am. J. Ophthalmol. , vol.130 , pp. 209-215
    • Mets, M.B.1    Barton, L.L.2    Khan, A.S.3    Ksiazek, T.G.4
  • 15
    • 0030052809 scopus 로고    scopus 로고
    • Lymphocytic choriomeningitis virus: a neglected central nervous system pathogen
    • Barton LL. 1996. Lymphocytic choriomeningitis virus: a neglected central nervous system pathogen. Clin. Infect. Dis. 22:197.
    • (1996) Clin. Infect. Dis. , vol.22 , pp. 197
    • Barton, L.L.1
  • 16
    • 0026651771 scopus 로고
    • Lymphocytic choriomeningitis virus: a neglected pathogen of man
    • Jahrling PB, Peters CJ. 1992. Lymphocytic choriomeningitis virus: a neglected pathogen of man. Arch. Pathol. Lab. Med. 116:486-488.
    • (1992) Arch. Pathol. Lab. Med. , vol.116 , pp. 486-488
    • Jahrling, P.B.1    Peters, C.J.2
  • 19
    • 84867357906 scopus 로고    scopus 로고
    • Possession, use, and transfer of select agents and toxins; biennial review
    • Federal Register
    • Federal Register. 2012. Possession, use, and transfer of select agents and toxins; biennial review. Final rule. Fed. Regist. 77:61083-61115.
    • (2012) Final rule. Fed. Regist. , vol.77 , pp. 61083-61115
  • 21
    • 0024294421 scopus 로고
    • Ribavirin therapy for lassa fever
    • Snell N. 1988. Ribavirin therapy for lassa fever. Practitioner 232:432.
    • (1988) Practitioner , vol.232 , pp. 432
    • Snell, N.1
  • 22
    • 11144316875 scopus 로고    scopus 로고
    • Hematologic side effects of interferon and ribavirin therapy
    • Kowdley KV. 2005. Hematologic side effects of interferon and ribavirin therapy. J. Clin. Gastroenterol. 39:S3-S8. http://dx.doi.org/10.1097/01.mcg.0000145494.76305.11.
    • (2005) J. Clin. Gastroenterol. , vol.39
    • Kowdley, K.V.1
  • 24
    • 31144445870 scopus 로고    scopus 로고
    • Mechanisms of action of ribavirin against distinct viruses
    • Graci JD, Cameron CE. 2006. Mechanisms of action of ribavirin against distinct viruses. Rev. Med. Virol. 16:37-48. http://dx.doi.org/10.1002/rmv.483.
    • (2006) Rev. Med. Virol. , vol.16 , pp. 37-48
    • Graci, J.D.1    Cameron, C.E.2
  • 27
    • 79958281626 scopus 로고    scopus 로고
    • Depletion of GTP pool is not the predominant mechanism by which ribavirin exerts its antiviral effect on Lassa virus
    • Olschlager S, Neyts J, Gunther S. 2011. Depletion of GTP pool is not the predominant mechanism by which ribavirin exerts its antiviral effect on Lassa virus. Antiviral Res. 91:89-93. http://dx.doi.org/10.1016/j.antiviral.2011.05.006.
    • (2011) Antiviral Res. , vol.91 , pp. 89-93
    • Olschlager, S.1    Neyts, J.2    Gunther, S.3
  • 29
    • 0027255241 scopus 로고
    • Molecular approaches for the treatment of hemorrhagic fever virus infections
    • Andrei G, De Clercq E. 1993. Molecular approaches for the treatment of hemorrhagic fever virus infections. Antiviral Res. 22:45-75. http://dx.doi.org/10.1016/0166-3542(93)90085-W.
    • (1993) Antiviral Res. , vol.22 , pp. 45-75
    • Andrei, G.1    De Clercq, E.2
  • 30
    • 77958577192 scopus 로고    scopus 로고
    • Development of a new tacaribe arenavirus infection model and its use to explore antiviral activity of a novel aristeromycin analog
    • Gowen BB, Wong MH, Larson D, Ye W, Jung KH, Sefing EJ, Skirps-tunas R, Smee DF, Morrey JD, Schneller SW. 2010. Development of a new tacaribe arenavirus infection model and its use to explore antiviral activity of a novel aristeromycin analog. PLoS One 5(9):e12760. http://dx.doi.org/10.1371/journal.pone.0012760.
    • (2010) PLoS One , vol.5 , Issue.9
    • Gowen, B.B.1    Wong, M.H.2    Larson, D.3    Ye, W.4    Jung, K.H.5    Sefing, E.J.6    Skirps-tunas, R.7    Smee, D.F.8    Morrey, J.D.9    Schneller, S.W.10
  • 31
    • 0038363947 scopus 로고    scopus 로고
    • Inactivation of S-adenosyl-L-homocysteine hydrolase with novel 5'-thioadenosine derivatives: antiviral effects
    • Guillerm G, Guillerm D, Vandenplas-Vitkowski C, Glapski C, De Clercq E. 2003. Inactivation of S-adenosyl-L-homocysteine hydrolase with novel 5'-thioadenosine derivatives: antiviral effects. Bioorg. Med. Chem. Lett. 13:1649-1652. http://dx.doi.org/10.1016/S0960-894X(03)00279-8.
    • (2003) Bioorg. Med. Chem. Lett. , vol.13 , pp. 1649-1652
    • Guillerm, G.1    Guillerm, D.2    Vandenplas-Vitkowski, C.3    Glapski, C.4    De Clercq, E.5
  • 32
    • 79955032440 scopus 로고    scopus 로고
    • Broadspectrum antiviral that interferes with de novo pyrimidine biosynthesis
    • Hoffmann HH, Kunz A, Simon VA, Palese P, Shaw ML. 2011. Broadspectrum antiviral that interferes with de novo pyrimidine biosynthesis. Proc. Natl. Acad. Sci. U. S. A. 108:5777-5782. http://dx.doi.org/10.1073/pnas.1101143108.
    • (2011) Proc. Natl. Acad. Sci. U. S. A. , vol.108 , pp. 5777-5782
    • Hoffmann, H.H.1    Kunz, A.2    Simon, V.A.3    Palese, P.4    Shaw, M.L.5
  • 33
    • 84855841164 scopus 로고    scopus 로고
    • The C-terminal region of lymphocytic choriomeningitis virus nucleoprotein contains distinct and segregable functional domains involved in NP-Z interaction and counteraction of the type I interferon response
    • Ortiz-Riano E, Cheng BY, de la Torre JC, Martinez-Sobrido L. 2011. The C-terminal region of lymphocytic choriomeningitis virus nucleoprotein contains distinct and segregable functional domains involved in NP-Z interaction and counteraction of the type I interferon response. J. Virol. 85:13038-13048. http://dx.doi.org/10.1128/JVI.05834-11.
    • (2011) J. Virol. , vol.85 , pp. 13038-13048
    • Ortiz-Riano, E.1    Cheng, B.Y.2    de la Torre, J.C.3    Martinez-Sobrido, L.4
  • 34
    • 78951490910 scopus 로고    scopus 로고
    • Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease
    • Emonet SF, Seregin AV, Yun NE, Poussard AL, Walker AG, de la Torre JC, Paessler S. 2011. Rescue from cloned cDNAs and in vivo characterization of recombinant pathogenic Romero and live-attenuated Candid #1 strains of Junin virus, the causative agent of Argentine hemorrhagic fever disease. J. Virol. 85:1473-1483. http://dx.doi.org/10.1128/JVI.02102-10.
    • (2011) J. Virol. , vol.85 , pp. 1473-1483
    • Emonet, S.F.1    Seregin, A.V.2    Yun, N.E.3    Poussard, A.L.4    Walker, A.G.5    de la Torre, J.C.6    Paessler, S.7
  • 37
    • 78951491212 scopus 로고    scopus 로고
    • Use of single-cycle infectious lymphocytic choriomeningitis virus to study hemorrhagic fever arenaviruses
    • Rodrigo WW, de la Torre JC, Martinez-Sobrido L. 2011. Use of single-cycle infectious lymphocytic choriomeningitis virus to study hemorrhagic fever arenaviruses. J. Virol. 85:1684-1695. http://dx.doi.org/10.1128/JVI.02229-10.
    • (2011) J. Virol. , vol.85 , pp. 1684-1695
    • Rodrigo, W.W.1    de la Torre, J.C.2    Martinez-Sobrido, L.3
  • 38
    • 79952073408 scopus 로고    scopus 로고
    • Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategies
    • Emonet SE, Urata S, de la Torre JC. 2011. Arenavirus reverse genetics: new approaches for the investigation of arenavirus biology and development of antiviral strategies. Virology 411:416-425. http://dx.doi.org/10.1016/j.virol.2011.01.013.
    • (2011) Virology , vol.411 , pp. 416-425
    • Emonet, S.E.1    Urata, S.2    de la Torre, J.C.3
  • 39
    • 0027270211 scopus 로고
    • Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction
    • Berridge MV, Tan AS. 1993. Characterization of the cellular reduction of 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT): subcellular localization, substrate dependence, and involvement of mitochondrial electron transport in MTT reduction. Arch. Biochem. Biophys. 303:474-482.
    • (1993) Arch. Biochem. Biophys. , vol.303 , pp. 474-482
    • Berridge, M.V.1    Tan, A.S.2
  • 40
    • 84861379061 scopus 로고    scopus 로고
    • The PI3K/Akt pathway contributes to arenavirus budding
    • Urata S, Ngo N, de la Torre JC. 2012. The PI3K/Akt pathway contributes to arenavirus budding. J. Virol. 86:4578-4585. http://dx.doi.org/10.1128/JVI.06604-11.
    • (2012) J. Virol. , vol.86 , pp. 4578-4585
    • Urata, S.1    Ngo, N.2    de la Torre, J.C.3
  • 42
    • 78649695759 scopus 로고    scopus 로고
    • Metabolomic analysis and visualization engine for LC-MS data
    • Melamud E, Vastag L, Rabinowitz JD. 2010. Metabolomic analysis and visualization engine for LC-MS data. Anal. Chem. 82:9818-9826. http://dx.doi.org/10.1021/ac10211166.
    • (2010) Anal. Chem. , vol.82 , pp. 9818-9826
    • Melamud, E.1    Vastag, L.2    Rabinowitz, J.D.3
  • 43
    • 0036830528 scopus 로고    scopus 로고
    • Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity
    • Baldwin J, Farajallah AM, Malmquist NA, Rathod PK, Phillips MA. 2002. Malarial dihydroorotate dehydrogenase. Substrate and inhibitor specificity. J. Biol. Chem. 277:41827-41834. http://dx.doi.org/10.1074/jbc.M206854200.
    • (2002) J. Biol. Chem. , vol.277 , pp. 41827-41834
    • Baldwin, J.1    Farajallah, A.M.2    Malmquist, N.A.3    Rathod, P.K.4    Phillips, M.A.5
  • 44
    • 20444470318 scopus 로고    scopus 로고
    • High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase
    • Baldwin J, Michnoff CH, Malmquist NA, White J, Roth MG, Rathod PK, Phillips MA. 2005. High-throughput screening for potent and selective inhibitors of Plasmodium falciparum dihydroorotate dehydrogenase. J. Biol. Chem. 280:21847-21853. http://dx.doi.org/10.1074/jbc.M501100200.
    • (2005) J. Biol. Chem. , vol.280 , pp. 21847-21853
    • Baldwin, J.1    Michnoff, C.H.2    Malmquist, N.A.3    White, J.4    Roth, M.G.5    Rathod, P.K.6    Phillips, M.A.7
  • 46
    • 0034102651 scopus 로고    scopus 로고
    • Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon
    • Markland W, McQuaid TJ, Jain J, Kwong AD. 2000. Broad-spectrum antiviral activity of the IMP dehydrogenase inhibitor VX-497: a comparison with ribavirin and demonstration of antiviral additivity with alpha interferon. Antimicrob. Agents Chemother. 44:859-866. http://dx.doi.org/10.1128/AAC.44.4.859-866.2000.
    • (2000) Antimicrob. Agents Chemother. , vol.44 , pp. 859-866
    • Markland, W.1    McQuaid, T.J.2    Jain, J.3    Kwong, A.D.4
  • 47
    • 0037333447 scopus 로고    scopus 로고
    • Role of the virus nucleoprotein in the regulation of lymphocytic choriomeningitis virus transcription and RNA replication
    • Pinschewer DD, Perez M, de la Torre JC. 2003. Role of the virus nucleoprotein in the regulation of lymphocytic choriomeningitis virus transcription and RNA replication. J. Virol. 77:3882-3887. http://dx.doi.org/10.1128/JVI.77.6.3882-3887.2003.
    • (2003) J. Virol. , vol.77 , pp. 3882-3887
    • Pinschewer, D.D.1    Perez, M.2    de la Torre, J.C.3
  • 48
    • 62549161807 scopus 로고    scopus 로고
    • Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest
    • Emonet SF, Garidou L, McGavern DB, de la Torre JC. 2009. Generation of recombinant lymphocytic choriomeningitis viruses with trisegmented genomes stably expressing two additional genes of interest. Proc. Natl. Acad. Sci. U. S. A. 106:3473-3478. http://dx.doi.org/10.1073/pnas.0900088106.
    • (2009) Proc. Natl. Acad. Sci. U. S. A. , vol.106 , pp. 3473-3478
    • Emonet, S.F.1    Garidou, L.2    McGavern, D.B.3    de la Torre, J.C.4
  • 49
    • 4043064372 scopus 로고    scopus 로고
    • Mammalian pyrimidine biosynthesis: fresh insights into an ancient pathway
    • Evans DR, Guy HI. 2004. Mammalian pyrimidine biosynthesis: fresh insights into an ancient pathway. J. Biol. Chem. 279:33035-33038. http://dx.doi.org/10.1074/jbc.R400007200.
    • (2004) J. Biol. Chem. , vol.279 , pp. 33035-33038
    • Evans, D.R.1    Guy, H.I.2
  • 50
    • 0344653661 scopus 로고    scopus 로고
    • Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives
    • Knecht W, Loffler M. 1998. Species-related inhibition of human and rat dihydroorotate dehydrogenase by immunosuppressive isoxazol and cinchoninic acid derivatives. Biochem. Pharmacol. 56:1259-1264.
    • (1998) Biochem. Pharmacol. , vol.56 , pp. 1259-1264
    • Knecht, W.1    Loffler, M.2
  • 51
    • 13744258758 scopus 로고    scopus 로고
    • The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase
    • Leyssen P, Balzarini J, De Clercq E, Neyts J. 2005. The predominant mechanism by which ribavirin exerts its antiviral activity in vitro against flaviviruses and paramyxoviruses is mediated by inhibition of IMP dehydrogenase. J. Virol. 79:1943-1947. http://dx.doi.org/10.1128/JVI.79.3.1943-1947.2005.
    • (2005) J. Virol. , vol.79 , pp. 1943-1947
    • Leyssen, P.1    Balzarini, J.2    De Clercq, E.3    Neyts, J.4
  • 52
    • 84870603707 scopus 로고    scopus 로고
    • Arenaviruses and lethal mutagenesis: prospects for new ribavirin-based interventions
    • Moreno H, Grande-Perez A, Domingo E, Martin V. 2012. Arenaviruses and lethal mutagenesis: prospects for new ribavirin-based interventions. Viruses 4:2786-2805. http://dx.doi.org/10.3390/v4112786.
    • (2012) Viruses , vol.4 , pp. 2786-2805
    • Moreno, H.1    Grande-Perez, A.2    Domingo, E.3    Martin, V.4
  • 54
    • 0029685786 scopus 로고    scopus 로고
    • Uracil metabolism. UMP synthesis from orotic acid or uridine and conversion of uracil to beta-alanine: enzymes and cDNAs
    • Traut TW, Jones ME. 1996. Uracil metabolism. UMP synthesis from orotic acid or uridine and conversion of uracil to beta-alanine: enzymes and cDNAs. Prog. Nucleic Acid Res. Mol. Biol. 53:1-78.
    • (1996) Prog. Nucleic Acid Res. Mol. Biol. , vol.53 , pp. 1-78
    • Traut, T.W.1    Jones, M.E.2
  • 55
    • 0032490145 scopus 로고    scopus 로고
    • Antiretroviral therapy for HIV infection: promises and problems
    • Volberding PA, Deeks SG. 1998. Antiretroviral therapy for HIV infection: promises and problems. JAMA 279:1343-1344. http://dx.doi.org/10.1001/jama.279.17.1343.
    • (1998) JAMA , vol.279 , pp. 1343-1344
    • Volberding, P.A.1    Deeks, S.G.2
  • 56
    • 84875228963 scopus 로고    scopus 로고
    • Sustained virologic response after therapy with the HCV protease inhibitor narlaprevir in combination with peginterferon and ribavirin is durable through long-term follow-up
    • Hotho DM, de Bruijne J, Spaan M, Treitel MA, Boonstra A, de Knegt RJ, Janssen HL, Reesink HW. 2013. Sustained virologic response after therapy with the HCV protease inhibitor narlaprevir in combination with peginterferon and ribavirin is durable through long-term follow-up. J. Viral Hepat. 20:e78-e81. http://dx.doi.org/10.1111/jvh.12012.
    • (2013) J. Viral Hepat. , vol.20
    • Hotho, D.M.1    de Bruijne, J.2    Spaan, M.3    Treitel, M.A.4    Boonstra, A.5    de Knegt, R.J.6    Janssen, H.L.7    Reesink, H.W.8
  • 57
    • 84876003945 scopus 로고    scopus 로고
    • Combination of MEK inhibitors and oseltamivir leads to synergistic antiviral effects after influenza A virus infection in vitro
    • Haasbach E, Hartmayer C, Planz O. 2013. Combination of MEK inhibitors and oseltamivir leads to synergistic antiviral effects after influenza A virus infection in vitro. Antiviral Res. 98:319-324. http://dx.doi.org/10.1016/j.antiviral.2013.03.006.
    • (2013) Antiviral Res. , vol.98 , pp. 319-324
    • Haasbach, E.1    Hartmayer, C.2    Planz, O.3
  • 58
    • 84877888607 scopus 로고    scopus 로고
    • An update of teriflunomide for treatment of multiple sclerosis
    • Oh J, O'Connor PW. 2013. An update of teriflunomide for treatment of multiple sclerosis. Ther. Clin. Risk Manag. 9:177-190. http://dx.doi.org/10.2147/TCRM.S30947.
    • (2013) Ther. Clin. Risk Manag. , vol.9 , pp. 177-190
    • Oh, J.1    O'Connor, P.W.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.