Lassa virus nucleoprotein mutants generated by reverse genetics induce a robust type I interferon response in human dendritic cells and macrophages

Journal of Virology

Volumn 85, Issue 22, 2011, Pages 12093-12097

  Carnec, Xavier ^a,c   Baize, Sylvain ^b   Reynard, Stéphanie ^b   Diancourt, Laure ^a   Caro, Valérie ^a   Tordo, Noel ^b   Bouloy, Michèle ^a  

^a INSTITUT PASTEUR   (France)

^b Institut Pasteur   (France)

^c Institut Universitaire d'Hématologie   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ADENINE; ALPHA1 INTERFERON; ALPHA2 INTERFERON; BETA INTERFERON; EXONUCLEASE; INTERFERON; THIAMINE; VIRUS NUCLEOPROTEIN; VIRUS RNA;

AFRICA; ANTIGEN PRESENTING CELL; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DENDRITIC CELL; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VIVO STUDY; INTERFERON INDUCTION; INTERFERON PRODUCTION; LASSA VIRUS; MACROPHAGE; NONHUMAN; NOTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VIRUS MUTATION; VIRUS REPLICATION; VIRUS TRANSCRIPTION;

AMINO ACID SUBSTITUTION; ANIMALS; CAPSID PROTEINS; CERCOPITHECUS AETHIOPS; DENDRITIC CELLS; INTERFERON TYPE I; LASSA VIRUS; MACROPHAGES; MOLECULAR SEQUENCE DATA; MUTANT PROTEINS; MUTATION, MISSENSE; SEQUENCE ANALYSIS, DNA; VERO CELLS; VIRAL LOAD; VIRAL PLAQUE ASSAY;

ARENAVIRIDAE; LASSA VIRUS; MURINAE;

EID: 80655125475     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.00429-11     Document Type: Note

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