MAP17, a ROS-dependent oncogene

Frontiers in Oncology

Volumn 2 SEP, Issue , 2012, Pages

  Carnero, Amancio ^a  

^a HOSPITAL UNIVERSITARIO VIRGEN DEL ROCÍO   (Spain)

Author keywords

Cancer; MAP17; Oncogene; Reactive oxygen species; Tumorigenesis

Indexed keywords

GUANINE NUCLEOTIDE BINDING PROTEIN; MAP 17; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANAEROBIC GLYCOLYSIS; BREAST TUMOR; CANCER GROWTH; CARBONYLATION; CARCINOGENESIS; DETOXIFICATION; DISULFIDE BOND; GENE TRANSLOCATION; GLUCOSE METABOLISM; HUMAN; IMMUNOHISTOCHEMISTRY; NITROSYLATION; NONHUMAN; ONCOGENE; PHENOTYPE; POINT MUTATION; POLYMERASE CHAIN REACTION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SHORT SURVEY;

EID: 84891656589     PISSN: None     EISSN: 2234943X     Source Type: Journal    
DOI: 10.3389/fonc.2012.00112     Document Type: Short Survey

References (66)

1. Abe, J., Okuda, M., Huang, Q., Yoshizumi, M., and Berk, B. C. (2000). Reactive oxygen species activate p90 ribosomal S6 kinase via Fyn and Ras. J. Biol. Chem. 275, 1739-1748.
2. Allen, R. G., and Tresini, M. (2000). Oxidative stress and gene regulation. Free Radic. Biol. Med. 28, 463-499.
3. Arnold, R. S., Shi, J., Murad, E., Whalen, A. M., Sun, C. Q., Polavarapu, R., Parthasarathy, S., Petros, J. A., and Lambeth, J. D. (2001). Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1. Proc. Natl. Acad. Sci. U.S.A. 98, 5550-5555.
4. Bae, G. U., Seo, D. W., Kwon, H. K., Lee, H. Y., Hong, S., Lee, Z. W., Ha, K. S., Lee, H. W., and Han, J. W. (1999). Hydrogen peroxide activates p70(S6k) signaling pathway. J. Biol. Chem. 274, 32596-32602.
5. Bar-Even, A., Flamholz, A., Noor, E., and Milo, R. (2012). Rethinking glycolysis: on the biochemical logic of metabolic pathways. Nat. Chem. Biol. 8, 509-517.
6. Barrett, W. C., DeGnore, J. P., Konig, S., Fales, H. M., Keng, Y. F., Zhang, Z. Y., Yim, M. B., and Chock, P. B. (1999). Regulation of PTP1B via glutathionylation of the active site cysteine 215. Biochemistry 38, 6699-6705.
7. Blasco, T., Aramayona, J., Alcalde, A., Catalan, J., Sarasa, M., and Sorribas, V. (2003). Rat kidney MAP17 induces cotransport of Na-mannose and Na-glucose in Xenopus laevis oocytes. Am. J. Physiol. Renal Physiol. 285, F799-F810.
8. Burdon, R. H. (1996). Control of cell proliferation by reactive oxygen species. Biochem. Soc. Trans. 24, 1028-1032.
9. Cardone, R. A., Bellizzi, A., Busco, G., Weinman, E. J., Dell'Aquila, M. E., Casavola, V., Azzariti, A., Mangia, A., Paradiso, A., and Reshkin, S. J. (2007). The NHERF1 PDZ2 domain regulates PKA-RhoA-p38-mediated NHE1 activation and invasion in breast tumor cells. Mol. Biol. Cell 18, 1768-1780.
10. Cardone, R. A., Casavola, V., and Reshkin, S. J. (2005). The role of disturbed pH dynamics and the Na+/H+ exchanger in metastasis. Nat. Rev. Cancer 5, 786-795.
11. Carnero, A. (2012). MAP17 and the double-edged sword of ROS. Biochim. Biophys. Acta 1826, 44-52.
12. Carnero, A., Hudson, J. D., Hannon, G. J., and Beach, D. H. (2000). Loss-of-function genetics in mammalian cells: the p53 tumor suppressor model. Nucleic Acids Res. 28, 2234-2241.
13. Chiche, J., Brahimi-Horn, M. C., and Pouyssegur, J. (2010). Tumour hypoxia induces a metabolic shift causing acidosis: a common feature in cancer. J. Cell. Mol. Med. 14, 771-794.
14. Church, S. L., Grant, J. W., Ridnour, L. A., Oberley, L. W., Swanson, P. E., Meltzer, P. S., and Trent, J. M. (1993). Increased manganese superoxide dismutase expression suppresses the malignant phenotype of human melanoma cells. Proc. Natl. Acad. Sci. U.S.A. 90, 3113-3117.
15. Cinar, A., Chen, M., Riederer, B., Bachmann, O., Wiemann, M., Manns, M., Kocher, O., and Seidler, U. (2007). NHE3 inhibition by cAMP and Ca2+ is abolished in PDZ-domain protein PDZK1-deficient murine enterocytes. J. Physiol. 581, 1235-1246.
16. Claperon, A., Mergey, M., and Fouassier, L. (2011). Roles of the scaffolding proteins NHERF in liver biology. Clin. Res. Hepatol. Gastroenterol. 35, 176-181.
17. 3-antiporters of bovine pigmented ciliary epithelial cells. Pflugers Arch. 440, 667-678.
18. Cunningham, R., Biswas, R., Steplock, D., Shenolikar, S., and Weinman, E. (2010). Role of NHERF and scaffolding proteins in proximal tubule transport. Urol. Res. 38, 257-262.
19. + exchanger regulatory factor) gene mutations in human breast cancer. Oncogene 23, 8681-8687.
20. Delabesse, E., Ogilvy, S., Chapman, M. A., Piltz, S. G., Gottgens, B., and Green, A. R. (2005). Transcriptional regulation of the SCL locus: identification of an enhancer that targets the primitive erythroid lineage in vivo. Mol. Cell. Biol. 25, 5215-5225.
21. Droge, W. (2002). Free radicals in the physiological control of cell function. Physiol. Rev. 82, 47-95.
22. England, K., and Cotter, T. G. (2005). Direct oxidative modifications of signalling proteins in mammalian cells and their effects on apoptosis. Redox Rep. 10, 237-245.
23. Fernandez-Pol, J. A., Hamilton, P. D., and Klos, D. J. (1982). Correlation between the loss of the transformed phenotype and an increase in superoxide dismutase activity in a revertant subclone of sarcoma virus-infected mammalian cells. Cancer Res. 42, 609-617.
24. Finkel, T. (1998). Oxygen radicals and signaling. Curr. Opin. Cell Biol. 10, 248-253.
25. Ganapathy, V., Thangaraju, M., Gopal, E., Martin, P. M., Itagaki, S., Miyauchi, S., and Prasad, P. D. (2008). Sodium-coupled monocarboxylate transporters in normal tissues and in cancer. AAPS J. 10, 193-199.
26. Gentzsch, M., Cui, L., Mengos, A., Chang, X. B., Chen, J. H., and Riordan, J. R. (2003). The PDZ-binding chloride channel ClC-3B localizes to the Golgi and associates with cystic fibrosis transmembrane conductance regulator-interacting PDZ proteins. J. Biol. Chem. 278, 6440-6449.
27. Gisler, S. M., Pribanic, S., Bacic, D., Forrer, P., Gantenbein, A., Sabourin, L. A., Tsuji, A., Zhao, Z. S., Manser, E., Biber, J., and Murer, H. (2003). PDZK1: I. A major scaffolder in brush borders of proximal tubular cells. Kidney Int. 64, 1733-1745.
28. Gottgens, B., Barton, L. M., Chapman, M. A., Sinclair, A. M., Knudsen, B., Grafham, D., Gilbert, J. G., Rogers, J., Bentley, D. R., and Green, A. R. (2002). Transcriptional regulation of the stem cell leukemia gene (SCL)-comparative analysis of five vertebrate SCL loci. Genome Res. 12, 749-759.
29. Guijarro, M. V., Castro, M. E., Romero, L., Moneo, V., and Carnero, A. (2007a). Large scale genetic screen identifies MAP17 as protein bypassing TNF-induced growth arrest. J. Cell. Biochem. 101, 112-121.
30. Guijarro, M. V., Leal, J. F., Blanco-Aparicio, C., Alonso, S., Fominaya, J., Lleonart, M., Castellvi, J., Ramon y Cajal, S., and Carnero, A. (2007b). MAP17 enhances the malignant behavior of tumor cells through ROS increase. Carcinogenesis 28, 2096-2104.
31. Guijarro, M. V., Leal, J. F., Fominaya, J., Blanco-Aparicio, C., Alonso, S., Lleonart, M., Castellvi, J., Ruiz, L., Ramon Y Cajal, S., and Carnero, A. (2007c). MAP17 overexpression is a common characteristic of carcinomas. Carcinogenesis 28, 1646-1652.
32. Guijarro, M. V., Link, W., Rosado, A., Leal, J. F., and Carnero, A. (2007d). MAP17 inhibits Myc-induced apoptosis through PI3K/AKT pathway activation. Carcinogenesis 28, 2443-2450.
33. Guijarro, M. V., Vergel, M., Marin, J. J., Munoz-Galvan, S., Ferrer, I., Cajal, S. R., Roncador, G., Blanco-Aparicio, C., and Carnero, A. (2012). p38α limits the contribution of MAP17 to cancer progression in breast tumors. Oncogene. doi: 10.1038/onc.2011.619 [Epub ahead of print].
34. Hainaut, P., and Milner, J. (1993). Redox modulation of p53 conformation and sequence-specific DNA binding in vitro. Cancer Res. 53, 4469-4473.
35. Hanahan, D., and Weinberg, R. (2000). The hallmarks of cancer. Cell 100, 57-70.
36. Hanahan, D., and Weinberg, R. A. (2011). Hallmarks of cancer: the next generation. Cell 144, 646-674.
37. Hannon, G. J., Sun, P., Carnero, A., Xie, L. Y., Maestro, R., Conklin, D. S., and Beach, D. (1999). MaRX: an approach to genetics in mammalian cells. Science 283, 1129-1130.
38. Hillesheim, J., Riederer, B., Tuo, B., Chen, M., Manns, M., Biber, J., Yun, C., Kocher, O., and Seidler, U. (2007). Down regulation of small intestinal ion transport in PDZK1-(CAP70/NHERF3) deficient mice. Pflugers Arch. 454, 575-586.
39. Inoue, J., Otsuki, T., Hirasawa, A., Imoto, I., Matsuo, Y., Shimizu, S., Taniwaki, M., and Inazawa, J. (2004). Overexpression of PDZK1 within the 1q12-q22 amplicon is likely to be associated with drug-resistance phenotype in multiple myeloma. Am. J. Pathol. 165, 71-81.
40. Irani, K., Xia, Y., Zweier, J. L., Sollott, S. J., Der, C. J., Fearon, E. R., Sundaresan, M., Finkel, T., and Goldschmidt-Clermont, P. J. (1997). Mitogenic signaling mediated by oxidants in Ras-transformed fibroblasts. Science 275, 1649-1652.
41. Jaeger, C., Schaefer, B., Wallich, R., and Kramer, M. (2000). The membrane-associated protein pKe#192/MAP17 in human keratinocytes. J. Invest. Dermatol. 115, 375-380.
42. Kim, J. K., Kwon, O., Kim, J., Kim, E. K., Park, H. K., Lee, J. E., Kim, K. L., Choi, J. W., Lim, S., Seok, H., Lee-Kwon, W., Choi, J. H., Kang, B. H., Kim, S., Ryu, S. H., and Suh, P. G. (2012). PDZ domain-containing 1 (PDZK1) protein regulates phospholipase C-beta3 (PLC-beta3)-specific activation of somatostatin by forming a ternary complex with PLC-beta3 and somatostatin receptors. J. Biol. Chem. 287, 21012-21024.
43. Klaunig, J. E., Xu, Y., Isenberg, J. S., Bachowski, S., Kolaja, K. L., Jiang, J., Stevenson, D. E., and Walborg, E. F. Jr. (1998). The role of oxidative stress in chemical carcinogenesis. Environ. Health Perspect. 106(Suppl. 1), 289-295.
44. Kocher, O., Cheresh, P., Brown, L. F., and Lee, S. W. (1995). Identification of a novel gene, selectively up-regulated in human carcinomas, using the differential display technique. Clin. Cancer Res. 1, 1209-1215.
45. Kocher, O., Cheresh, P., and Lee, S. W. (1996). Identification and partial characterization of a novel mem-brane-associated protein (MAP17) up-regulated in human carcinomas and modulating cell replication and tumor growth. Am. J. Pathol. 149, 493-500.
46. Lanaspa, M. A., Giral, H., Breusegem, S. Y., Halaihel, N., Baile, G., Catalan, J., Carrodeguas, J. A., Barry, N. P., Levi, M., and Sorribas, V. (2007). Interaction of MAP17 with NHERF3/4 induces translocation of the renal Na/Pi IIa transporter to the trans-Golgi. Am. J. Physiol. Renal Physiol. 292, F230-F242.
47. Lee, S. R., Kwon, K. S., Kim, S. R., and Rhee, S. G. (1998). Reversible inactivation of protein-tyrosine phosphatase 1B in A431 cells stimulated with epidermal growth factor. J. Biol. Chem. 273, 15366-15372.
48. +/glucose cotransporters in renal proximal tubule cells. Kidney Int. Suppl. 72, S27-S35.
49. 2 in Swiss 3T3 fibroblasts. J. Biol. Chem. 273, 29986-29994.
50. Natarajan, V., Taher, M. M., Roehm, B., Parinandi, N. L., Schmid, H. H., Kiss, Z., and Garcia, J. G. (1993). Activation of endothelial cell phospholipase D by hydrogen peroxide and fatty acid hydroperoxide. J. Biol. Chem. 268, 930-937.
51. Parks, S. K., Chiche, J., and Pouyssegur, J. (2011). pH control mechanisms of tumor survival and growth. J. Cell. Physiol. 226, 299-308.
52. Pribanic, S., Gisler, S., Bacic, D., Madjdpour, C., Hernando, N., Sorribas, V., Gantenbein, A., Biber, J., and Murer, H. (2003). Interactions of MAP17 with the NaPi-IIa/PDZK1 protein complex in renal proximal tubular cells. Am. J. Physiol. Renal Physiol. 285, F784-F791.
53. Ray, P. D., Huang, B. W., and Tsuji, Y. (2012). Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling. Cell. Signal. 24, 981-990.
54. Schmidt, K. N., Amstad, P., Cerutti, P., and Baeuerle, P. A. (1995). The roles of hydrogen peroxide and superoxide as messengers in the activation of transcription factor NF-kappa B. Chem. Biol. 2, 13-22.
55. Shenolikar, S., Voltz, J. W., Cunningham, R., and Weinman, E. J. (2004). Regulation of ion transport by the NHERF family of PDZ proteins. Physiology (Bethesda) 19, 362-369.
56. Silver, D. L., Wang, N., and Vogel, S. (2003). Identification of small PDZK1-associated protein, DD96/MAP17, as a regulator of PDZK1 and plasma high density lipoprotein levels. J. Biol. Chem. 278, 28528-28532.
57. Sudheerkumar, P., Shiras, A., Das, G., Jagtap, J. C., Prasad, V., and Shastry, P. (2008). Independent activation of Akt and NF-kappaB pathways and their role in resistance to TNF-alpha mediated cytotoxicity in gliomas. Mol. Carcinog. 47, 126-136.
58. Sugiura, T., Kato, Y., Wakayama, T., Silver, D. L., Kubo, Y., Iseki, S., and Tsuji, A. (2008). PDZK1 regulates two intestinal solute carriers (Slc15a1 and Slc22a5) in mice. Drug Metab. Dispos. 36, 1181-1188.
59. 2 for platelet-derived growth factor signal transduction. Science 270, 296-299.
60. Theisen, C. S., Wahl, J. K. III, Johnson, K. R., and Wheelock, M. J. (2007). NHERF links the N-cadherin/catenin complex to the platelet-derived growth factor receptor to modulate the actin cytoskeleton and regulate cell motility. Mol. Biol. Cell 18, 1220-1232.
61. Vergel, M., and Carnero, A. (2010). Bypassing cellular senescence by genetic screening tools. Clin. Transl. Oncol. 12, 410-417.
62. Vurusaner, B., Poli, G., and Basaga, H. (2012). Tumor suppressor genes and ROS: complex networks of interactions. Free Radic. Biol. Med. 52, 7-18.
63. Weinman, E. J., Biswas, R., Steplock, D., Douglass, T. S., Cunningham, R., and Shenolikar, S. (2010). Sodium-hydrogen exchanger regulatory factor 1 (NHERF-1) transduces signals that mediate dopamine inhibition of sodium-phosphate co-transport in mouse kidney. J. Biol. Chem. 285, 13454-13460.
64. Wenk, J., Brenneisen, P., Wlaschek, M., Poswig, A., Briviba, K., Oberley, T. D., and Scharffetter-Kochanek, K. (1999). Stable overexpression of manganese superoxide dismutase in mitochondria identifies hydrogen peroxide as a major oxidant in the AP-1-mediated induction of matrix-degrading metalloprotease-1. J. Biol. Chem. 274, 25869-25876.
65. Xu, X., Tu, L., Jiang, W., Feng, W., Zhao, C. X., and Wang, D. W. (2012). Bradykinin prevents the apoptosis of NIT-1 cells induced by TNF-alpha via the PI3K/Akt and MAPK signaling pathways. Int. J. Mol. Med. 29, 891-898.
66. Yan, T., Oberley, L. W., Zhong, W., and St Clair, D. K. (1996). Manganese-containing superoxide dismutase overexpression causes phenotypic reversion in SV40-transformed human lung fibroblasts. Cancer Res. 56, 2864-2871.