PDZ domain-containing 1 (PDZK1) protein regulates phospholipase C-β3 (PLC-β3)-specific activation of somatostatin by forming a ternary complex with PLC-β3 and somatostatin receptors

Journal of Biological Chemistry

Volumn 287, Issue 25, 2012, Pages 21012-21024

  Kim, Jung Kuk ^a,b   Kwon, Ohman ^a   Kim, Jinho ^a   Kim, Eung Kyun ^b   Park, Hye Kyung ^b   Lee, Ji Eun ^b   Kim, Kyung Lock ^a   Choi, Jung Woong ^a   Lim, Seyoung ^a   Seok, Heon ^b   Lee Kwon, Whaseon ^b   Choi, Jang Hyun ^b   Kang, Byoung Heon ^b   Kim, Sanguk ^a   Ryu, Sung Ho ^a   Suh, Pann Ghill ^a,b  

^a Pohang University of Science and Technology (POSTECH)   (South Korea)

^b Ulsan National Institute of Science and Technology   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; PHYSIOLOGY;

COMPLEX FORMATIONS; G-PROTEIN COUPLED RECEPTORS; INTRACELLULAR CA; PDZ BINDING MOTIF; PHOSPHOLIPASE C; PHYSIOLOGICAL FUNCTIONS; SOMATOSTATIN RECEPTORS; TERNARY COMPLEX;

PROTEINS;

CALCIUM ION; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PDZ DOMAIN CONTAINING 1 PROTEIN; PDZ PROTEIN; PHOSPHOLIPASE C BETA3; SOMATOSTATIN; SOMATOSTATIN RECEPTOR; TERNARY COMPLEX FACTOR; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BINDING SITE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CALCIUM SIGNALING; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; PRIORITY JOURNAL; PROTEIN ASSEMBLY; PROTEIN BINDING; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; SCREENING TEST; WESTERN BLOTTING;

EID: 84862271827     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.337865     Document Type: Article

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