Promoting antitumor activities of hydroxycamptothecin by encapsulation into acid-labile nanoparticles using electrospraying

Pharmaceutical Research

Volumn 31, Issue 1, 2014, Pages 46-59

  Luo, Xiaoming ^a   Jia, Guoqing ^a   Song, Haixing ^b   Liu, Chaoyu ^a   Wu, Guannan ^a   Li, Xiaohong ^a  

^a SOUTHWEST JIAOTONG UNIVERSITY   (China)

^b CHENGDU MEDICAL COLLEGE   (China)

Author keywords

acid lability; antitumor activity; biodistribution; electrosprayed nanoparticles; targeting capability

Indexed keywords

ANTINEOPLASTIC AGENT; GALACTOSE; HYDROXYCAMPTOTHECIN; NANOPARTICLE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL STRAIN HEPG2; CIRCULATION TIME; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; ELECTROSPRAY; ENCAPSULATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MOUSE; NONHUMAN; PH; PRIORITY JOURNAL; SURVIVAL RATE; TISSUE NECROSIS; TUMOR GROWTH; TUMOR MICROENVIRONMENT;

ACIDS; ANIMALS; ANTINEOPLASTIC AGENTS; CAMPTOTHECIN; CELL LINE, TUMOR; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; HEP G2 CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; MICE; NANOPARTICLES; TECHNOLOGY, PHARMACEUTICAL;

EID: 84891634185     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-013-1130-4     Document Type: Article

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