In silico studies in probing the role of kinetic and structural effects of different drugs for the reactivation of tabun-inhibited AChE

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Lo, Rabindranath ^a   Chandar, Nellore Bhanu ^a   Kesharwani, Manoj K ^a   Jain, Aastha ^a   Ganguly, Bishwajit ^a  

^a CSIR CENTRAL SALT AND MARINE CHEMICALS RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

3 HYDROXY 2 PYRIDINEALDOXIME; ACETYLCHOLINESTERASE; BISPYRIDINIUM OXIME; DEAZAPRALIDOXIME; MONOPYRIDINIUM OXIME; OXIME DERIVATIVE; TABUN; UNCLASSIFIED DRUG;

ANALYTIC METHOD; ARTICLE; BINDING AFFINITY; COMPUTER MODEL; DENSITY FUNCTIONAL THEORY; ENZYME ACTIVATION; ENZYME KINETICS; ENZYME REACTIVATION; ENZYME STABILITY; ENZYME STRUCTURE; HYDROGEN BOND; PROTEIN INTERACTION; STRUCTURE ANALYSIS;

ACETYLCHOLINESTERASE; ANIMALS; CHEMICAL WARFARE AGENTS; GPI-LINKED PROTEINS; KINETICS; MICE; MOLECULAR DOCKING SIMULATION; ORGANOPHOSPHATES;

EID: 84891596086     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079591     Document Type: Article

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