Bactofencin A, a new type of cationic bacteriocin with Unusual Immunity

mBio

Volumn 4, Issue 6, 2013, Pages

  O'Shea, Eileen F ^a,c   O'Connor, Paula M ^a,c   O'Sullivan, Orla ^a   Cotter, Paul D ^a,c   Ross, R Paul ^a,c   Hill, Colin ^b,c  

^a TEAGASC FOOD RESEARCH CENTRE   (Ireland)

^b UNIVERSITY COLLEGE CORK   (Ireland)

^c UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; ANTIINFECTIVE AGENT; BACTERIOCIN; BACTOFENCIN A; PROTEIN; TRANSPORT ACCESSORY PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL GROWTH; BACTERIAL IMMUNITY; BACTERIUM IDENTIFICATION; BACTERIUM ISOLATION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; GENE CLUSTER; GENE EXPRESSION; GENE SEQUENCE; GENETIC ANALYSIS; GROWTH INHIBITION; HUMAN; LACTOBACILLUS SALIVARIUS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MICROBIAL ACTIVITY; MOLECULAR WEIGHT; NONHUMAN; NUCLEOTIDE SEQUENCE; OPERON; PRIORITY JOURNAL; SPECTROSCOPY; STAPHYLOCOCCUS AUREUS;

ALANINE TRANSAMINASE; ANIMALS; ANTI-BACTERIAL AGENTS; BACTERIOCINS; DRUG RESISTANCE, BACTERIAL; LACTOBACILLUS; LISTERIA MONOCYTOGENES; MOLECULAR WEIGHT; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; STAPHYLOCOCCUS AUREUS; SWINE;

EID: 84891594474     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00498-13     Document Type: Article

References (64)

1. Claesson MJ, van Sinderen D, O'Toole PW. 2008. Lactobacillus phylogenomics-towards a reclassification of the genus. Int. J. Syst. Evol. Micro biol. 58:2945-2954.
2. Wiedemann I, Böttiger T, Bonelli RR, Schneider T, Sahl HG, Martínez B. 2006. Lipid II-based antimicrobial activity of the lantibiotic plantaricin C. Appl. Environ. Microbiol. 72:2809-2814.
3. Joerger MC, Klaenhammer TR. 1986. Characterization and purification of helveticin J and evidence for a chromosomally determined bacteriocin produced by Lactobacillus helveticus 481. J. Bacteriol. 167:439-446
4. Barrett E, Hayes M, O'Connor P, Gardiner G, Fitzgerald GF, Stanton C, Ross RP, Hill C. 2007. Salivaricin P: one of a family of two component anti-listerial bacteriocins produced by intestinal isolates of Lactobacillus salivarius. Appl. Environ. Microbiol. 73:3719-3723.
5. Dunne C, Murphy L, Flynn S, O'Mahony L, O'Halloran S, Feeney M, Morrissey D, Thornton G, Fitzgerald G, Daly C, Kiely B, Quigley EM, O'Sullivan GC, Shanahan F, Collins JK. 1999. Probiotics: from myth to reality. Demonstration of functionality in animal models of disease and in human clinical trials. Antonie Van Leeuwenhoek 76:279-292.
6. Li Y, Canchaya C, Fang F, Raftis E, Ryan KA, van Pijkeren JP, van Sinderen D, O'Toole PW. 2007. Distribution of megaplasmids in Lactobacillus salivarius and other lactobacilli. J. Bacteriol. 189:6128-6139.
7. Martín R, Jiménez E, Olivares M, Marín ML, Fernández L, Xaus J, Rodríguez JM. 2006. Lactobacillus salivarius CECT 5713, a potential probiotic strain isolated from infant feces and breast milk of a mother-child pair. Int. J. Food Microbiol. 112:35-43.
8. Neville BA, O'Toole PW. 2010. Probiotic properties of Lactobacillus salivarius and closely related Lactobacillus species. Future Microbiol. 5:759-774.
9. Timmerman HM, Niers LE, Ridwan BU, Koning CJ, Mulder L, Akkermans LM, Rombouts FM, Rijkers GT. 2007. Design of a multispecies probiotic mixture to prevent infectious complications in critically ill patients. Clin. Nutr. 26:450-459.
10. Walsh MC, Gardiner GE, Hart OM, Lawlor PG, Daly M, Lynch B, Richert BT, Radcliffe S, Giblin L, Hill C, Fitzgerald GF, Stanton C, Ross P. 2008. Predominance of a bacteriocin-producing Lactobacillus salivarius component of a five-strain probiotic in the porcine ileum and effects on host immune phenotype. FEMS Microbiol. Ecol. 64:317-327.
11. Arroyo R, Martín V, Maldonado A, Jiménez E, Fernández L, Rodríguez JM. 2010. Treatment of infectious mastitis during lactation: antibiotics versus oral administration of Lactobacilli isolated from breast milk. Clin. Infect. Dis. 50:1551-1558.
12. Jiménez E, Fernández L, Maldonado A, Martín R, Olivares M, Xaus J, Rodríguez JM. 2008. Oral administration of Lactobacillus strains isolated from breast milk as an alternative for the treatment of infectious mastitis during lactation. Appl. Environ. Microbiol. 74:4650-4655.
13. Lara-Villoslada F, Sierra S, Díaz-Ropero MP, Olivares M, Xaus J. 2007. Safety assessment of the human milk-isolated probiotic Lactobacillus salivarius CECT5713. J. Dairy Sci. 90:3583-3589.
14. Maldonado J, Lara-Villoslada F, Sierra S, Sempere L, Gómez M, Rodriguez JM, Boza J, Xaus J, Olivares M. 2010. Safety and tolerance of the human milk probiotic strain Lactobacillus salivarius CECT5713 in 6-month-old children. Nutrition 26:1082-1087.
15. Sierra S, Lara-Villoslada F, Sempere L, Olivares M, Boza J, Xaus J. 2010. Intestinal and immunological effects of daily oral administration of Lactobacillus salivarius CECT5713 to healthy adults. Anaerobe 16:195-200.
16. Stern NJ, Svetoch EA, Eruslanov BV, Perelygin VV, Mitsevich EV, Mitsevich IP, Pokhilenko VD, Levchuk VP, Svetoch OE, Seal BS. 2006. Isolation of a Lactobacillus salivarius strain and purification of its bacteriocin, which is inhibitory to Campylobacter jejuni in the chicken gastrointestinal system. Antimicrob. Agents Chemother. 50:3111-3116.
17. Svetoch EA, Eruslanov BV, Levchuk VP, Perelygin VV, Mitsevich EV, Mitsevich IP, Stepanshin J, Dyatlov I, Seal BS, Stern NJ. 2011. Isolation of Lactobacillus salivarius 1077 (NRRL B-50053) and characterization of its bacteriocin, including the antimicrobial activity spectrum. Appl. Environ. Microbiol. 77:2749-2754.
18. Cho YJ, Choi JK, Kim JH, Lim YS, Ham JS, Kang DK, Chun J, Paik HD, Kim GB. 2011. Genome sequence of Lactobacillus salivarius GJ-24, a probiotic strain isolated from healthy adult intestine. J. Bacteriol. 193: 5021-5022.
19. Flynn S, van Sinderen D, Thornton GM, Holo H, Nes IF, Collins JK. 2002. Characterization of the genetic locus responsible for the production of ABP-118, a novel bacteriocin produced by the probiotic bacterium Lactobacillus salivarius subsp. salivarius UCC118. Microbiology 148: 973-984.
20. Kergourlay G, Messaoudi S, Dousset X, Prévost H. 2012. Genome sequence of Lactobacillus salivarius SMXD51, a potential probiotic strain isolated from chicken cecum, showing anti-Campylobacter activity. J. Bacteriol. 194:3008-3009.
21. O'Shea EF, O'Connor PM, Raftis EJ, O'Toole PW, Stanton C, Cotter PD, Ross RP, Hill C. 2011. Production of multiple bacteriocins from a single locus by gastrointestinal strains of Lactobacillus salivarius. J. Bacteriol. 193:6973-6982.
22. Pilasombut K, Sakpuaram T, Wajjwalku W, Nitisinprasert S, Swetwiwathana A, Zendo T, Fujita K, Nakayama J, Sonomoto K. 2006. Pur fication and amino acid sequence of a bacteriocin produced by Lactobacillus salivarius K7 isolated from chicken intestine. Songklanakarin J. Sci. Technol. 28:121-131.
23. Vera Pingitore E, Hébert EM, Nader-Macías ME, Sesma F. 2009. Chaacterization of salivaricin CRL 1328, a two-peptide bacteriocin produced by Lactobacillus salivarius CRL 1328 isolated from the human vagina. Res. Microbiol. 160:401-408.
24. Cataloluk O. 2001. Molecular characterization of the gene encoding for the salivaricin B activity and its flanking sequences. Turk. J. Biol. 25: 379-386.
25. Murphy EF, Cotter PD, Hogan A, O'Sullivan O, Joyce A, Fouhy F, Clarke SF, Marques TM, O'Toole PW, Stanton C, Quigley EM, Daly C, Ross PR, O'Doherty RM, Shanahan F. 2013. Divergent metabolic outcomes arising from targeted manipulation of the gut microbiota in dietinduced obesity. Gut 62:220-226.
26. Riboulet-Bisson E, Sturme MH, Jeffery IB, O'Donnell MM, Neville BA, Forde BM, Claesson MJ, Harris H, Gardiner GE, Casey PG, Lawlor PG, O'Toole PW, Ross RP. 2012. Effect of Lactobacillus salivarius bacteriocin Abp118 on the mouse and pig intestinal microbiota. PLoS One 7:e31113. doi:10.1371/journal.pone.0031113.
27. O'Shea EF, Gardiner GE, O'Connor PM, Mills S, Ross RP, Hill C. 2009.Characterization of enterocin and salivaricin-producing lactic acid bacteria from the mammalian gastrointestinal tract. FEMS Microbiol. Lett. 291:24-34.
28. Claesson MJ, Li Y, Leahy S, Canchaya C, van Pijkeren JP, CerdeñoTárraga AM, Parkhill J, Flynn S, O'Sullivan GC, Collins JK, Higgins D, Shanahan F, Fitzgerald GF, van Sinderen D, O'Toole PW. 2006. Multireplicon genome architecture of Lactobacillus salivarius. Proc. Natl. Acad. Sci. U. S. A. 103:6718-6723.
29. Wang G, Li X, Wang Z. 2009. APD2: the updated antimicrobial peptide database and its application in peptide design. Nucleic Acids Res. 37: D933-D937.
30. Tailor RH, Acland DP, Attenborough S, Cammue BP, Evans IJ, Osborn RW, Ray JA, Rees SB, Broekaert WF. 1997. A novel family of small cysteine-rich antimicrobial peptides from seed of Impatiens balsamina is derived from a single precursor protein. J. Biol. Chem. 272:24480-24487.
31. Perego M, Glaser P, Minutello A, Strauch MA, Leopold K, Fischer W. 1995. Incorporation of D-alanine into lipoteichoic acid and wall teichoic acid in Bacillus subtilis. Identification of genes and regulation. J. Biol. Chem. 270:15598-15606.
32. Peschel A, Otto M, Jack RW, Kalbacher H, Jung G, Götz F. 1999. Inactivation of the dlt operon in Staphylococcus aureus confers sensitivity to defensins, protegrins, and other antimicrobial peptides. J. Biol. Chem. 274:8405-8410.
33. Abi Khattar Z, Rejasse A, Destoumieux-Garzon D, Escoubas JM, Sanchis V, Lereclus D, Givaudan A, Kallassy M, Nielsen-Leroux C, Gaudriault S. 2009. The dlt operon of Bacillus cereus is required for resistance to cationic antimicrobial peptides and for virulence in insects. J. Bacteriol. 191:7063-7073.
34. Kramer NE, Hasper HE, van den Bogaard PT, Morath S, de Kruijff B, Hartung T, Smid EJ, Breukink E, Kok J, Kuipers OP. 2008. Increased D-alanylation of lipoteichoic acid and a thickened septum are main determinants in the nisin resistance mechanism of Lactococcus lactis. Microbi-ology 154:1755-1762.
35. Kramer NE, van Hijum SA, Knol J, Kok J, Kuipers OP. 2006. Transcriptome analysis reveals mechanisms by which Lactococcus lactis aquires nisin resistance. Antimicrob. Agents Chemother. 50:1753-1761.
36. Sass P, Bierbaum G. 2009. Native graS mutation supports the susceptibility of Staphylococcus aureus strain SG511 to antimicrobial peptides. Int. J. Med. Microbiol. 299:313-322.
37. Michiels J, Dirix G, Vanderleyden J, Xi C. 2001. Processing and exportof peptide pheromones and bacteriocins in gram-negative bacteria. Trends Microbiol. 9:164-168.
38. Nes IF, Diep DB, Håvarstein LS, Brurberg MB, Eijsink V, Holo H. 1996. Biosynthesis of bacteriocins in lactic acid bacteria. Antonie Van Leeuwenhoek 70:113-128.
39. Dubrac S, Bisicchia P, Devine KM, Msadek T. 2008. A matter of life and death: cell wall homeostasis and the WalKR (YycGF) essential signal transduction pathway. Mol. Microbiol. 70:1307-1322.
40. Arakawa K, Kawai Y, Ito Y, Nakamura K, Chujo T, Nishimura J, Kitazawa H, Saito T. 2010. HPLC purification and re-evaluation of chemical identity of two circular bacteriocins, gassericin A and reutericin 6. Lett. Appl. Microbiol. 50:406-411.
41. Inoue T, Tomita H, Ike Y. 2006. Bac 32, a novel bacteriocin widely disseminated among clinical isolates of Enterococcus faecium. Antimicrob. Agents Chemother. 50:1202-1212.
42. Marcille F, Gomez A, Joubert P, Ladiré M, Veau G, Clara A, Gavini F, Willems A, Fons M. 2002. Distribution of genes encoding the trypsindependent lantibiotic ruminococcin A among bacteria isolated from human fecal microbiota. Appl. Environ. Microbiol. 68:3424-3431.
43. Raftis EJ, Salvetti E, Torriani S, Felis GE, O'Toole PW. 2011. Genomic diversity of Lactobacillus salivarius. Appl. Environ. Microbiol. 77: 954-965.
44. Rea MC, Ross RP, Cotter PD, Hill C. 2011. Classification of bacteriocins from Gram-positive bacteria, p 29-53. In Drider D, Rebuffat S (ed), Prokaryotic antimicrobial peptides. Springer-Verlag, New York, NY.
45. Klostermann K. 2009. Alternative therapies for mastitis treatment and prevention in Dairy cows: antimicrobial peptides and probiotic bacteria. Ph.D. thesis. University College Cork, Cork, Ireland.
46. O'Shea EF, O'Connor PM, Cotter PD, Ross RP, Hill C. 2010. Synthesis of trypsin-resistant variants of the Listeria-active bacteriocin salivaricin P. Appl. Environ. Microbiol. 76:5356-5362.
47. Casey PG, Gardiner GE, Casey G, Bradshaw B, Lawlor PG, Lynch PB, Leonard FC, Stanton C, Ross RP, Fitzgerald GF, Hill C. 2007. A five-strain probiotic combination reduces pathogen shedding and alleviates disease signs in pigs challenged with Salmonella enterica serovar Typhimurium. Appl. Environ. Microbiol. 73:1858-1863.
48. Cotter PD, Deegan LH, Lawton EM, Draper LA, O'Connor PM, Hill C, Ross RP. 2006. Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design. Mol. Microbiol. 62:735-747.
49. Altermann E, Klaenhammer TR. 2003. GAMOLA: a new local solution for sequence annotation and analyzing draft and finished prokaryotic genomes. Omics 7:161-169.
50. Delcher AL, Bratke KA, Powers EC, Salzberg SL. 2007. Identifying bacterial genes and endosymbiont DNA with Glimmer. Bioinformatics 23:673-679.
51. Altschul SF, Madden TL, Schäffer AA, Zhang J, Zhang Z, Miller W, Lipman DJ. 1997. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25:3389-3402.
52. Carver T, Berriman M, Tivey A, Patel C, Böhme U, Barrell BG, Parkhill J, Rajandream MA. 2008. Artemis and ACT: viewing, annotating and comparing sequences stored in a relational database. Bioinformatics 24: 2672-2676.
53. Myers EW, Miller W. 1988. Optimal alignments in linear space. Comput. Appl. Biosci. 4:11-17.
54. Field D, Quigley L, O'Connor PM, Rea MC, Daly K, Cotter PD, Hill C, Ross RP. 2010. Studies with bioengineered nisin peptides highlight the broad-spectrum potency of nisin V. Microb. Biotechnol. 3:479-496.
55. McGrath S, Fitzgerald GF, van Sinderen D. 2001. Improvement and optimization of two engineered phage resistance mechanisms in Lactococcus lactis. Appl. Environ. Microbiol. 67:608-616.
56. Dobson A. 2011. The impact of the broad-spectrum antimicrobial peptide, lacticin 3147 on complex microbial communities. Ph.D. thesis. University College Cork, Cork, Ireland.
57. Fitzgerald JR. 2007. Targeted gene disruption for the analysis of virulence of Staphylococcus aureus. Methods Mol. Biol. 391:103-112.
58. Luchansky JB, Muriana PM, Klaenhammer TR. 1988. Application of electroporation for transfer of plasmid DNA to Lactobacillus, Lactococcus, Leuconostoc, Listeria, Pediococcus, Bacillus, Staphylococcus, Enterococcus and Propionibacterium. Mol. Microbiol. 2:637-646.
59. Park SF, Stewart GS. 1990. High-efficiency transformation of Listeria monocytogenes by electroporation of penicillin-treated cells. Gene 94: 129-132.
60. Sambrook J, Fritsch EF, Maniatis T. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory, Cold Spring Harbor, NY.
61. Corr SC, Li Y, Riedel CU, O'Toole PW, Hill C, Gahan CG. 2007. Bacteriocin production as a mechanism for the antiinfective activity of Lactobacillus salivarius UCC118. Proc. Natl. Acad. Sci. U. S. A. 104: 7617-7621.
62. O'Flynn G, Ross RP, Fitzgerald GF, Coffey A. 2004. Evaluation of a cocktail of three bacteriophages for biocontrol of Escherichia coli O157: H7. Appl. Environ. Microbiol. 70:3417-3424.
63. Kent RM, Guinane CM, O'Connor PM, Fitzgerald GF, Hill C, Stanton C, Ross RP. 2012. Production of the antimicrobial peptides caseicin A and B by Bacillus isolates growing on sodium caseinate. Lett. Appl. Microbiol. 55:141-148
64. Horgan M, O'Flynn G, Garry J, Cooney J, Coffey A, Fitzgerald GF, Ross RP, McAuliffe O. 2009. Phage lysin LysK can be truncated to its CHAP domain and retain lytic activity against live antibiotic-resistant staphylococci. Appl. Environ. Microbiol. 75:872-874.