Improvement and optimization of two engineered phage resistance mechanisms in Lactococcus lactis

Applied and Environmental Microbiology

Volumn 67, Issue 2, 2001, Pages 608-616

  McGrath, S ^a   Fitzgerald, G F ^a   Van Sinderen, D ^a  

^a UNIVERSITY COLLEGE CORK   (Ireland)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIOPHAGE DNA; DNA FRAGMENT;

MICROBIOLOGY;

ARTICLE; BACTERIOPHAGE; DNA REPLICATION; DNA SEQUENCE; GENETIC ENGINEERING; LACTOCOCCUS LACTIS; NONHUMAN; NUCLEOTIDE SEQUENCE; VIRUS RESISTANCE;

BACTERIAL PROTEINS; BACTERIOPHAGES; BLOTTING, NORTHERN; BLOTTING, SOUTHERN; CLONING, MOLECULAR; DNA REPLICATION; GENETIC ENGINEERING; LACTOCOCCUS LACTIS; MOLECULAR SEQUENCE DATA; REPLICATION ORIGIN; RNA, ANTISENSE; RNA, MESSENGER; SEQUENCE ANALYSIS, DNA;

EID: 0035145881     PISSN: 00992240     EISSN: None     Source Type: Journal    
DOI: 10.1128/AEM.67.2.608-616.2001     Document Type: Article

References (47)

1. Molecular characterization of three small isometric-headed bacteriophages which vary in their sensitivity to the lactococcal phage resistance plasmid pTR2030
2. Phage resistance mechanisms in lactic acid bacteria
3. Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
4. Molecular characterization of lactococcal bacteriophage Tuc2009 and identification and analysis of genes encoding lysin, a putative holin, and two structural proteins
5. The Bacillus subtilis bacteriophage SPP1 G39P delivers and activates the G40P DNA helicase upon interacting with the G38P-bound replication origin
6. Homologous recombination between a lactococcal bacteriophage and the chromosome of its host strain
7. Antisense RNA directed against the major capsid protein of Lactococcus lactis subsp. cremoris bacteriophage 4-1 confers partial resistance to the host
8. Cloning and nucleotide sequence of the major capsid protein from Lactococcus lactis ssp. cremoris bacteriophage F4-1
9. Application and evaluation of the phage resistance- and bacteriocin-encoding plasmid pMRC01 for the improvement of dairy starter cultures
10. Identification and characterization of a plasmid encoding abortive infection from Lactococcus lactis subsp. lactis UC811
11. Biotechnology of lactic acid bacteria with special reference to bacteripophage resistance
12. Controlled gene expression systems for Lactococcus lactis with the food-grade inducer nisin
13. A triggered-suicide system designed as a defense against bacteriophages
14. Genetic analysis of chromosomal regions of Lactococcus lactis acquired by recombinant lytic phages
15. A short noncoding viral DNA element showing characteristics of a replication origin confers bacteriophage resistance to Streptococcus thermophilus
16. Identification of four phage resistance plasmids from Lactococcus lactis subsp. cremoris HO2
17. Molecular genetics of bacteriophage and natural phage defence systems in the genus Lactococcus
18. Construction of a bacteriophage-resistant derivative of Lactococcus lactis subsp. lactis 425A by using the conjugal plasmid pNP40
19. Bacteriophage and bacteriophage resistance in lactic acid bacteria
20. Cloning, expression, and sequence determination of a bacteriophage fragment encoding bacteriophage resistance in Lactococcus lactis
21. Antisense RNA: Its functions and applications in gene regulation - A review
22. Bacteriophages of lactic acid bacteria
23. Sources of lactic streptococcal phages in cheese plants
24. Use of antisense RNA to confer bacteriophage resistance in dairy starter cultures
25. Antisense mRNA-mediated bacteriophage resistance in Lactococcus lactis subsp. lactis
26. Bacteriophage resistance in Lactococcus lactis ssp. lactis using antisense ribonucleic acid
27. Bacteriophage and bacteriophage resistance
28. An improved plaque assay for poor plaque-producing temperate lactococcal bacteriophages
29. Prokaryotic DNA replication
30. Molecular characterization of a phage-encoded resistance system in Lactococcus lactis
31. The distribution of lactococcal bacteriophage in the environment of a cheese manufacturing plant
32. Isolation and characterization of lactococcal bacteriophages from cultured buttermilk plants in the United States
33. Characterization of lactococcal bacteriophages from Quebec cheese plants
34. Evolution of a lytic bacteriophage via DNA acquisition from the Lactococcus lactis chromosome
35. Restriction/modification systems and restriction endonucleases are more effective on lactococcal bacteriophages that have emerged recently in the dairy industry
36. Design of a phage-insensitive lactococcal dairy starter via sequential transfer of naturally occurring conjugative plasmids
37. Effect of increasing the copy number of bacteriophage origins of replication in trans on incoming phage proliferation
38. Analysis of cis and trans acting elements required for the initiation of DNA replication in the Bacillus subtilis bacteriophage SPP1
39. Conjugal transfer of bacteriophage resistance determinants on pTR2030 into Streptococcus cremoris strains
40. Identification of four loci isolated from two Streptococcus thermophilus phage genomes responsible for mediating bacteriophage resistance
41. Isolation and characterization of Lactococcus lactis subsp. cremoris Wg2-specific promoters
42. Sequence analysis and molecular characterization of the temperate lactococcal bacteriophage rlt
43. An explosive antisense RNA strategy for inhibition of a lactococcal bacteriophage
44. Molecular characterization of a phage-inducible middle promoter and its transcriptional activator from the lactococcal bacteriophage phi31
45. Improved cloning vectors and transformation procedure for Lactococcus lactis