Possible synergistic effect of direct angiotensin II type 2 receptor stimulation by compound 21 with memantine on prevention of cognitive decline in type 2 diabetic mice

European Journal of Pharmacology

Volumn 724, Issue 1, 2014, Pages 9-15

  Iwanami, Jun ^a   Mogi, Masaki ^a   Tsukuda, Kana ^a   Jing, Fei ^a   Ohshima, Kousei ^a   Wang, Xiao Li ^a   Nakaoka, Hirotomo ^a   Kan No, Harumi ^a   Chisaka, Toshiyuki ^a   Bai, Hui Yu ^a   Min, Li Juan ^a   Horiuchi, Masatsugu ^a  

^a EHIME UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Acetylcholine; AT2 receptor; Cerebral blood flow; Diabetes mellitus; Memantine

Indexed keywords

ACETYLCHOLINE; ANGIOTENSIN 2 RECEPTOR; COMPOUND 21; HORMONE RECEPTOR AFFECTING AGENT; MEMANTINE; UNCLASSIFIED DRUG;

ACETYLCHOLINE RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG EFFECT; DRUG POTENTIATION; ESCAPE BEHAVIOR; EXCITATORY POSTSYNAPTIC POTENTIAL; LATENT PERIOD; MAZE TEST; MOUSE; NEUROPROTECTION; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL;

ACETYLCHOLINE; AT(2) RECEPTOR; CEREBRAL BLOOD FLOW; DIABETES MELLITUS; MEMANTINE;

ANIMALS; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBROVASCULAR CIRCULATION; COGNITION DISORDERS; CYTOKINES; DIABETES MELLITUS, TYPE 2; DRUG SYNERGISM; EXCITATORY AMINO ACID ANTAGONISTS; EXCITATORY POSTSYNAPTIC POTENTIALS; MAZE LEARNING; MEMANTINE; MICE; RECEPTOR, ANGIOTENSIN, TYPE 2; RECEPTORS, N-METHYL-D-ASPARTATE; SULFONAMIDES; THIOPHENES;

EID: 84891538539     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2013.12.015     Document Type: Article

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