Effects of memantine and donepezil on cortical and hippocampal acetylcholine levels and object recognition memory in rats

Neuropharmacology

Volumn 61, Issue 5-6, 2011, Pages 891-899

  Ihalainen, Jouni ^a   Sarajärvi, Timo ^a   Rasmusson, Doug ^b   Kemppainen, Susanna ^a   Keski Rahkonen, Pekka ^a   Lehtonen, Marko ^a   Banerjee, Pradeep K ^c   Semba, Kazue ^b   Tanila, Heikki ^a,d  

^a UNIVERSITY OF EASTERN FINLAND   (Finland)

^b DALHOUSIE UNIVERSITY   (Canada)

^c FOREST RESEARCH INSTITUTE   (United States)

^d KUOPIO UNIVERSITY HOSPITAL   (Finland)

Author keywords

Acetylcholine; Alzheimer's disease; Hippocampus; In vivo microdialysis; Memantine; Recognition memory

Indexed keywords

ACETYLCHOLINE; DONEPEZIL; MEMANTINE; NEOSTIGMINE; PLACEBO;

ACETYLCHOLINE BRAIN LEVEL; ACETYLCHOLINE RELEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN FORNIX; BRAIN REGION; CONTROLLED STUDY; DOSAGE SCHEDULE COMPARISON; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG SCREENING; FIMBRIA; HIPPOCAMPUS; LONG TERM CARE; MALE; MONOTHERAPY; NEOCORTEX; NONHUMAN; PRIORITY JOURNAL; RAT; SCORING SYSTEM; SHORT TERM MEMORY; SINGLE DRUG DOSE; SYSTEMIC THERAPY; TASK PERFORMANCE; TREATMENT DURATION;

ACETYLCHOLINE; ANIMALS; CHOLINESTERASE INHIBITORS; COGNITION; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG EVALUATION, PRECLINICAL; DRUG SYNERGISM; EXCITATORY AMINO ACID ANTAGONISTS; FORNIX, BRAIN; HIPPOCAMPUS; INDANS; MALE; MEMANTINE; NEOCORTEX; PIPERIDINES; RATS; RATS, WISTAR; RECOGNITION (PSYCHOLOGY);

EID: 80051799419     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2011.06.008     Document Type: Article

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