Pyrrolizines: Promising scaffolds for anticancer drugs

Bioorganic and Medicinal Chemistry

Volumn 22, Issue 1, 2014, Pages 46-53

  Belal, Amany ^a,b   El Gendy, Bahaa El Dien M ^c  

^a Beni Suef University   (Egypt)

^b TAIF UNIVERSITY   (Saudi Arabia)

^c BENHA UNIVERSITY   (Egypt)

Author keywords

Anticancer drugs; Indolo pyrrolizine; Perhydropyrrolizines; Pyrimido pyrrolizines; Pyrrolizines; Pyrrolo pyrrolizine; SAR; Thieno pyrrolizines

Indexed keywords

ANTINEOPLASTIC AGENT; CISPLATIN; DOXORUBICIN; FLUOROURACIL; LICOFELONE; MITOMYCIN DERIVATIVE; PHENETHYLIDENEPYRROLIZINONE; PRODRUG; PYRROLIZINE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; BREAST ADENOCARCINOMA; BREAST CARCINOMA; CANCER INHIBITION; DNA CROSS LINKING; DRUG CYTOTOXICITY; DRUG SYNTHESIS; HUMAN; IC 50; LEUKEMIA P 388; LEWIS CARCINOMA; MELANOMA B16; PLASMACYTOMA; PROSTATE ADENOCARCINOMA; REVIEW; SARCOMA; SOLID TUMOR; STEREOCHEMISTRY; STRUCTURE ACTIVITY RELATION; TUMOR REGRESSION; TUMOR XENOGRAFT; WALKER CARCINOMA;

ANTICANCER DRUGS; INDOLO PYRROLIZINE; PERHYDROPYRROLIZINES; PYRIMIDO PYRROLIZINES; PYRROLIZINES; PYRROLO PYRROLIZINE; SAR; THIENO PYRROLIZINES;

ANTINEOPLASTIC AGENTS; HUMANS; PYRROLES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84891488798     PISSN: 09680896     EISSN: 14643391     Source Type: Journal    
DOI: 10.1016/j.bmc.2013.11.040     Document Type: Review

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