Star-branched amphiphilic PLA-b-PDMAEMA copolymers for co-delivery of miR-21 inhibitor and doxorubicin to treat glioma

Biomaterials

Volumn 35, Issue 7, 2014, Pages 2322-2335

  Qian, Xiaomin ^a   Long, Lixia ^a   Shi, Zhendong ^b   Liu, Chaoyong ^a   Qiu, Mingzhe ^b   Sheng, Jing ^a   Pu, Peiyu ^b   Yuan, Xubo ^a   Ren, Yu ^b   Kang, Chunsheng ^b  

^a TIANJIN UNIVERSITY   (China)

^b TIANJIN MEDICAL UNIVERSITY   (China)

Author keywords

Co delivery; MiR 21; Polydimethylaminoethyl methacrylate; Polylactic acid; Star branched copolymer; Synergistic effects

Indexed keywords

CO DELIVERIES; MIR-21; POLY LACTIC ACID; POLYDIMETHYLAMINOETHYL METHACRYLATE; STAR-BRANCHED; SYNERGISTIC EFFECT;

ARCHITECTURE; ATOM TRANSFER RADICAL POLYMERIZATION; COPOLYMERS; CRITICAL MICELLE CONCENTRATION; EFFICIENCY; GENES; MICELLES; POLYESTERS; POLYMERIZATION; RNA; TUMORS;

POLYMER BLENDS;

ANTINEOPLASTIC AGENT; COPOLYMER; DOXORUBICIN; MICRORNA 21; MICRORNA 21 INHIBITOR; NANOPARTICLE; POLY[2 (DIMETHYLAMINO)ETHYL METHACRYLATE]; POLYLACTIC ACID; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; ATOM TRANSFER RADICAL POLYMERIZATION; CLICK CHEMISTRY; CONTROLLED STUDY; CRITICAL MICELLE CONCENTRATION; CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG POTENTIATION; DRUG RELEASE; GENETIC TRANSFECTION; GLIOMA; GLIOMA CELL; LYSOSOME; MOUSE; NANOENCAPSULATION; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; RING OPENING METATHESIS POLYMERIZATION; SYNTHESIS; TUMOR VOLUME; ZETA POTENTIAL;

CO-DELIVERY; MIR-21; POLYDIMETHYLAMINOETHYL METHACRYLATE; POLYLACTIC ACID; STAR-BRANCHED COPOLYMER; SYNERGISTIC EFFECTS;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; BRAIN NEOPLASMS; DOXORUBICIN; GLIOMA; IN SITU HYBRIDIZATION, FLUORESCENCE; METHACRYLATES; MICE; MICE, INBRED BALB C; MICE, NUDE; MICRORNAS; MICROSCOPY, ELECTRON, TRANSMISSION; POLYESTERS;

EID: 84891372908     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2013.11.039     Document Type: Article

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