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Volumn 19, Issue 2, 2013, Pages 98-108

Aspirin-/TMZ-coloaded Microspheres Exert Synergistic Antiglioma Efficacy via Inhibition of β-catenin Transactivation

Author keywords

catenin; Aspirin; Combination chemotherapy; Microspheres; TMZ

Indexed keywords

ACETYLSALICYLIC ACID; BETA CATENIN; CTNNB1 PROTEIN; MICROSPHERE; POLYGLACTIN; PROTEIN; PROTEIN KINASE B; PROTEIN KINASE B BETA; STAT3 PROTEIN; TCF4 PROTEIN; TEMOZOLOMIDE; UNCLASSIFIED DRUG;

EID: 84872688686     PISSN: 17555930     EISSN: 17555949     Source Type: Journal    
DOI: 10.1111/cns.12041     Document Type: Article
Times cited : (23)

References (41)
  • 1
    • 33746052131 scopus 로고    scopus 로고
    • Synthesis and characterization of PLGA nanoparticles
    • Astete CE, Sabliov CM. Synthesis and characterization of PLGA nanoparticles. J Biomater Sci Polym Ed 2006;17:247-289.
    • (2006) J Biomater Sci Polym Ed , vol.17 , pp. 247-289
    • Astete, C.E.1    Sabliov, C.M.2
  • 2
    • 83655165245 scopus 로고    scopus 로고
    • Poly Lactic-co-Glycolic Acid (PLGA) as biodegradable controlled drug delivery carrier
    • Makadia HK, Siegel SJ. Poly Lactic-co-Glycolic Acid (PLGA) as biodegradable controlled drug delivery carrier. Polymers 2011;3:1377-1397.
    • (2011) Polymers , vol.3 , pp. 1377-1397
    • Makadia, H.K.1    Siegel, S.J.2
  • 3
    • 51849084844 scopus 로고    scopus 로고
    • Self-assembled lipid-polymer hybrid nanoparticles: a robust drug delivery platform
    • Zhang L, Chan JM, Gu FX, et al. Self-assembled lipid-polymer hybrid nanoparticles: a robust drug delivery platform. ACS Nano 2008;2:1696-1702.
    • (2008) ACS Nano , vol.2 , pp. 1696-1702
    • Zhang, L.1    Chan, J.M.2    Gu, F.X.3
  • 4
    • 84864584221 scopus 로고    scopus 로고
    • Effects of local delivery of bFGF from PLGA microspheres on osseointegration around implants in diabetic rats
    • Zou GK, Song YL, Zhou W, et al. Effects of local delivery of bFGF from PLGA microspheres on osseointegration around implants in diabetic rats. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2012;114:284-289.
    • (2012) Oral Surg Oral Med Oral Pathol Oral Radiol Endod , vol.114 , pp. 284-289
    • Zou, G.K.1    Song, Y.L.2    Zhou, W.3
  • 5
    • 80053480063 scopus 로고    scopus 로고
    • A comparative study of neural and mesenchymal stem cell-based carriers for oncolytic adenovirus in a model of malignant glioma
    • Ahmed AU, Tyler MA, Thaci B, et al. A comparative study of neural and mesenchymal stem cell-based carriers for oncolytic adenovirus in a model of malignant glioma. Mol Pharmaceut 2011;8:1559-1572.
    • (2011) Mol Pharmaceut , vol.8 , pp. 1559-1572
    • Ahmed, A.U.1    Tyler, M.A.2    Thaci, B.3
  • 6
    • 48649086682 scopus 로고    scopus 로고
    • Mechanisms of disease: temozolomide and glioblastoma-look to the future
    • Mrugala MM, Chamberlain MC. Mechanisms of disease: temozolomide and glioblastoma-look to the future. Nat Clin Pract Oncol 2008;5:476-486.
    • (2008) Nat Clin Pract Oncol , vol.5 , pp. 476-486
    • Mrugala, M.M.1    Chamberlain, M.C.2
  • 7
    • 84855468776 scopus 로고    scopus 로고
    • Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients
    • Agnihotri S, Gajadhar AS, Ternamian C, et al. Alkylpurine-DNA-N-glycosylase confers resistance to temozolomide in xenograft models of glioblastoma multiforme and is associated with poor survival in patients. J Clin Invest 2012;122:253-266.
    • (2012) J Clin Invest , vol.122 , pp. 253-266
    • Agnihotri, S.1    Gajadhar, A.S.2    Ternamian, C.3
  • 8
    • 83055188336 scopus 로고    scopus 로고
    • Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas
    • Motomura K, Natsume A, Wakabayashi T. Intravenous administration of temozolomide as a useful alternative over oral treatment with temozolomide capsules in patients with gliomas. J Neurooncol 2012;106:209-211.
    • (2012) J Neurooncol , vol.106 , pp. 209-211
    • Motomura, K.1    Natsume, A.2    Wakabayashi, T.3
  • 10
    • 49649104978 scopus 로고    scopus 로고
    • Mechanisms of chemoresistance to alkylating agents in malignant glioma
    • Sarkaria JN, Kitange GJ, James CD, et al. Mechanisms of chemoresistance to alkylating agents in malignant glioma. Clin Cancer Res 2008;14:2900-2908.
    • (2008) Clin Cancer Res , vol.14 , pp. 2900-2908
    • Sarkaria, J.N.1    Kitange, G.J.2    James, C.D.3
  • 11
    • 84865988896 scopus 로고    scopus 로고
    • Sequence-dependent synergistic inhibition of human glioma cell lines by combined Temozolomide and miR-21 inhibitor gene therapy
    • Qian X, Ren Y, Shi Z, et al. Sequence-dependent synergistic inhibition of human glioma cell lines by combined Temozolomide and miR-21 inhibitor gene therapy. Mol Pharmaceut 2012;9:2636-2645.
    • (2012) Mol Pharmaceut , vol.9 , pp. 2636-2645
    • Qian, X.1    Ren, Y.2    Shi, Z.3
  • 12
    • 77950355734 scopus 로고    scopus 로고
    • Anti-inflammatory agents: present and future
    • Dinarello CA. Anti-inflammatory agents: present and future. Cell 2010;140:935-950.
    • (2010) Cell , vol.140 , pp. 935-950
    • Dinarello, C.A.1
  • 13
    • 77950346282 scopus 로고    scopus 로고
    • Immunity, inflammation, and cancer
    • Grivennikov SI, Greten FR, Karin M. Immunity, inflammation, and cancer. Cell 2010;140:883-899.
    • (2010) Cell , vol.140 , pp. 883-899
    • Grivennikov, S.I.1    Greten, F.R.2    Karin, M.3
  • 15
    • 68849123400 scopus 로고    scopus 로고
    • Aspirin use and survival after diagnosis of colorectal cancer
    • Chan AT, Ogino S, Fuchs CS. Aspirin use and survival after diagnosis of colorectal cancer. JAMA 2009;302:649-658.
    • (2009) JAMA , vol.302 , pp. 649-658
    • Chan, A.T.1    Ogino, S.2    Fuchs, C.S.3
  • 16
    • 80053389973 scopus 로고    scopus 로고
    • Antitumor effect of aspirin in glioblastoma cells by modulation of beta-catenin/T-cell factor-mediated transcriptional activity
    • Lan F, Yue X, Han L, et al. Antitumor effect of aspirin in glioblastoma cells by modulation of beta-catenin/T-cell factor-mediated transcriptional activity. J Neurosurg 2011;115:780-788.
    • (2011) J Neurosurg , vol.115 , pp. 780-788
    • Lan, F.1    Yue, X.2    Han, L.3
  • 17
    • 84863534138 scopus 로고    scopus 로고
    • MicroRNA-21 Expression is regulated by beta-catenin/STAT3 Pathway and Promotes Glioma Cell Invasion by Direct Targeting RECK
    • Han L, Yue X, Zhou X, et al. MicroRNA-21 Expression is regulated by beta-catenin/STAT3 Pathway and Promotes Glioma Cell Invasion by Direct Targeting RECK. CNS Neurosci Ther 2012;18:573-583.
    • (2012) CNS Neurosci Ther , vol.18 , pp. 573-583
    • Han, L.1    Yue, X.2    Zhou, X.3
  • 18
    • 0442325056 scopus 로고    scopus 로고
    • About the evaluation of drug combination
    • Jin ZJ. About the evaluation of drug combination. Acta Pharmacol Sin 2004;25:146-147.
    • (2004) Acta Pharmacol Sin , vol.25 , pp. 146-147
    • Jin, Z.J.1
  • 19
    • 84864717408 scopus 로고    scopus 로고
    • VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1alpha/VEGF and beta-catenin/Tcf-4 signaling
    • Chen L, Han L, Zhang K, et al. VHL regulates the effects of miR-23b on glioma survival and invasion via suppression of HIF-1alpha/VEGF and beta-catenin/Tcf-4 signaling. Neuro Oncol 2012;14:1026-1036.
    • (2012) Neuro Oncol , vol.14 , pp. 1026-1036
    • Chen, L.1    Han, L.2    Zhang, K.3
  • 20
    • 80055026027 scopus 로고    scopus 로고
    • Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through the GSK-3beta/beta-catenin signaling pathway
    • Li C, Zhou C, Wang S, et al. Sensitization of glioma cells to tamoxifen-induced apoptosis by Pl3-kinase inhibitor through the GSK-3beta/beta-catenin signaling pathway. PLoS ONE 2011;6:e27053.
    • (2011) PLoS ONE , vol.6
    • Li, C.1    Zhou, C.2    Wang, S.3
  • 21
    • 79960861074 scopus 로고    scopus 로고
    • Beta-catenin/Tcf-4 complex transcriptionally regulates AKT1 in glioma
    • Chen L, Huang K, Han L, et al. Beta-catenin/Tcf-4 complex transcriptionally regulates AKT1 in glioma. Int J Oncol 2011;39:883-890.
    • (2011) Int J Oncol , vol.39 , pp. 883-890
    • Chen, L.1    Huang, K.2    Han, L.3
  • 22
    • 79959951151 scopus 로고    scopus 로고
    • High beta-catenin/Tcf-4 activity confers glioma progression via direct regulation of AKT2 gene expression
    • Zhang J, Huang K, Shi Z, et al. High beta-catenin/Tcf-4 activity confers glioma progression via direct regulation of AKT2 gene expression. Neuro Oncol 2011;13:600-609.
    • (2011) Neuro Oncol , vol.13 , pp. 600-609
    • Zhang, J.1    Huang, K.2    Shi, Z.3
  • 23
    • 79251611366 scopus 로고    scopus 로고
    • Interruption of beta-catenin suppresses the EGFR pathway by blocking multiple oncogenic targets in human glioma cells
    • Yue X, Lan F, Yang W, et al. Interruption of beta-catenin suppresses the EGFR pathway by blocking multiple oncogenic targets in human glioma cells. Brain Res 2010;1366:27-37.
    • (2010) Brain Res , vol.1366 , pp. 27-37
    • Yue, X.1    Lan, F.2    Yang, W.3
  • 24
    • 80053150736 scopus 로고    scopus 로고
    • Inhibition of STAT3 reverses alkylator resistance through modulation of the AKT and beta-catenin signaling pathways
    • Wang Y, Chen L, Bao Z, et al. Inhibition of STAT3 reverses alkylator resistance through modulation of the AKT and beta-catenin signaling pathways. Oncol Rep 2011;26:1173-1180.
    • (2011) Oncol Rep , vol.26 , pp. 1173-1180
    • Wang, Y.1    Chen, L.2    Bao, Z.3
  • 25
    • 79954626807 scopus 로고    scopus 로고
    • Beta-catenin and Gli1 are prognostic markers in glioblastoma
    • Rossi M, Magnoni L, Miracco C, et al. Beta-catenin and Gli1 are prognostic markers in glioblastoma. Cancer Biol Ther 2011;11:753-761.
    • (2011) Cancer Biol Ther , vol.11 , pp. 753-761
    • Rossi, M.1    Magnoni, L.2    Miracco, C.3
  • 26
    • 0036208462 scopus 로고    scopus 로고
    • A phase II study of extended low-dose temozolomide in recurrent malignant gliomas
    • Khan RB, Raizer JJ, Malkin MG, Bazylewicz KA, Abrey LE. A phase II study of extended low-dose temozolomide in recurrent malignant gliomas. Neuro Oncol 2002;4:39-43.
    • (2002) Neuro Oncol , vol.4 , pp. 39-43
    • Khan, R.B.1    Raizer, J.J.2    Malkin, M.G.3    Bazylewicz, K.A.4    Abrey, L.E.5
  • 27
    • 84875860073 scopus 로고    scopus 로고
    • Nuclear Translocation of beta-catenin is Essential for Glioma Cell Survival
    • DOI: 10.1007/s11481-012-9354-3
    • Shi Z, Qian X, Li L, et al. Nuclear Translocation of beta-catenin is Essential for Glioma Cell Survival. J Neuroimmune Pharm 2012; DOI: 10.1007/s11481-012-9354-3
    • (2012) J Neuroimmune Pharm
    • Shi, Z.1    Qian, X.2    Li, L.3
  • 28
    • 84863399038 scopus 로고    scopus 로고
    • Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised led trials
    • Rothwell PM, Wilson M, Price JF, Belch JF, Meade TW, Mehta Z. Effect of daily aspirin on risk of cancer metastasis: a study of incident cancers during randomised led trials. Lancet 2012;379:1591-1601.
    • (2012) Lancet , vol.379 , pp. 1591-1601
    • Rothwell, P.M.1    Wilson, M.2    Price, J.F.3    Belch, J.F.4    Meade, T.W.5    Mehta, Z.6
  • 29
    • 77955982423 scopus 로고    scopus 로고
    • Studies on the preparation, characterization and pharmacological evaluation of tolterodine PLGA microspheres
    • Sun F, Sui C, Teng L, Liu X, Meng Q, Li Y. Studies on the preparation, characterization and pharmacological evaluation of tolterodine PLGA microspheres. Int J Pharm 2010;397:44-49.
    • (2010) Int J Pharm , vol.397 , pp. 44-49
    • Sun, F.1    Sui, C.2    Teng, L.3    Liu, X.4    Meng, Q.5    Li, Y.6
  • 30
    • 82255193043 scopus 로고    scopus 로고
    • Effect of PLGA hydrophilia on the drug release and the hypoglucemic activity of different insulin-loaded PLGA microspheres
    • Presmanes C, De Miguel L, Espada R, Alvarez C, Morales E, Torrado JJ. Effect of PLGA hydrophilia on the drug release and the hypoglucemic activity of different insulin-loaded PLGA microspheres. J Microencapsul 2011;28:791-798.
    • (2011) J Microencapsul , vol.28 , pp. 791-798
    • Presmanes, C.1    De Miguel, L.2    Espada, R.3    Alvarez, C.4    Morales, E.5    Torrado, J.J.6
  • 31
    • 79960283601 scopus 로고    scopus 로고
    • Insulin-loaded PLGA microparticles: flow focusing versus double emulsion/solvent evaporation
    • Cozar-Bernal MJ, Holgado MA, Arias JL, et al. Insulin-loaded PLGA microparticles: flow focusing versus double emulsion/solvent evaporation. J Microencapsul 2011;28:430-441.
    • (2011) J Microencapsul , vol.28 , pp. 430-441
    • Cozar-Bernal, M.J.1    Holgado, M.A.2    Arias, J.L.3
  • 32
    • 45749098900 scopus 로고    scopus 로고
    • AKT is activated in an ataxia-telangiectasia and Rad3-related-dependent manner in response to temozolomide and confers protection against drug-induced cell growth inhibition
    • Caporali S, Levati L, Starace G, et al. AKT is activated in an ataxia-telangiectasia and Rad3-related-dependent manner in response to temozolomide and confers protection against drug-induced cell growth inhibition. Mol Pharmacol 2008;74:173-183.
    • (2008) Mol Pharmacol , vol.74 , pp. 173-183
    • Caporali, S.1    Levati, L.2    Starace, G.3
  • 33
    • 78549288561 scopus 로고    scopus 로고
    • MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature
    • Gaspar N, Marshall L, Perryman L, et al. MGMT-independent temozolomide resistance in pediatric glioblastoma cells associated with a PI3-kinase-mediated HOX/stem cell gene signature. Cancer Res 2010;70:9243-9252.
    • (2010) Cancer Res , vol.70 , pp. 9243-9252
    • Gaspar, N.1    Marshall, L.2    Perryman, L.3
  • 34
    • 79953052206 scopus 로고    scopus 로고
    • Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide
    • Prasad G, Sottero T, Yang X, et al. Inhibition of PI3K/mTOR pathways in glioblastoma and implications for combination therapy with temozolomide. Neuro Oncol 2011;13:384-392.
    • (2011) Neuro Oncol , vol.13 , pp. 384-392
    • Prasad, G.1    Sottero, T.2    Yang, X.3
  • 35
    • 67349103358 scopus 로고    scopus 로고
    • Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide
    • Sinnberg T, Lasithiotakis K, Niessner H, et al. Inhibition of PI3K-AKT-mTOR signaling sensitizes melanoma cells to cisplatin and temozolomide. J Invest Dermatol 2009;129:1500-1515.
    • (2009) J Invest Dermatol , vol.129 , pp. 1500-1515
    • Sinnberg, T.1    Lasithiotakis, K.2    Niessner, H.3
  • 36
    • 19444385692 scopus 로고    scopus 로고
    • Stat3 regulates genes common to both wound healing and cancer
    • Dauer DJ, Ferraro B, Song L, et al. Stat3 regulates genes common to both wound healing and cancer. Oncogene 2005;24:3397-3408.
    • (2005) Oncogene , vol.24 , pp. 3397-3408
    • Dauer, D.J.1    Ferraro, B.2    Song, L.3
  • 37
    • 58149144782 scopus 로고    scopus 로고
    • Constitutively activated STAT3 frequently coexpresses with epidermal growth factor receptor in high-grade gliomas and targeting STAT3 sensitizes them to Iressa and alkylators
    • Lo HW, Cao X, Zhu H, Ali-Osman F. Constitutively activated STAT3 frequently coexpresses with epidermal growth factor receptor in high-grade gliomas and targeting STAT3 sensitizes them to Iressa and alkylators. Clin Cancer Res 2008;14:6042-6054.
    • (2008) Clin Cancer Res , vol.14 , pp. 6042-6054
    • Lo, H.W.1    Cao, X.2    Zhu, H.3    Ali-Osman, F.4
  • 38
    • 34248202709 scopus 로고    scopus 로고
    • Targeting multiple arms of the apoptotic regulatory machinery
    • Dai Y, Grant S. Targeting multiple arms of the apoptotic regulatory machinery. Cancer Res 2007;67:2908-2911.
    • (2007) Cancer Res , vol.67 , pp. 2908-2911
    • Dai, Y.1    Grant, S.2
  • 39
    • 84863131190 scopus 로고    scopus 로고
    • Paclitaxel/tetrandrine coloaded nanoparticles effectively promote the apoptosis of gastric cancer cells based on "oxidation therapy"
    • Li X, Lu X, Xu H, et al. Paclitaxel/tetrandrine coloaded nanoparticles effectively promote the apoptosis of gastric cancer cells based on "oxidation therapy". Mol Pharmaceut 2012;9:222-229.
    • (2012) Mol Pharmaceut , vol.9 , pp. 222-229
    • Li, X.1    Lu, X.2    Xu, H.3
  • 40
    • 0035139792 scopus 로고    scopus 로고
    • Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer
    • Yamamoto Y, Gaynor RB. Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancer. J Clin Invest 2001;107:135-142.
    • (2001) J Clin Invest , vol.107 , pp. 135-142
    • Yamamoto, Y.1    Gaynor, R.B.2
  • 41
    • 84858718448 scopus 로고    scopus 로고
    • NF-kappaB and the link between inflammation and cancer
    • DiDonato JA, Mercurio F, Karin M. NF-kappaB and the link between inflammation and cancer. Immunol Rev 2012;246:379-400.
    • (2012) Immunol Rev , vol.246 , pp. 379-400
    • DiDonato, J.A.1    Mercurio, F.2    Karin, M.3


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