Bcl-2 upregulation induced by miR-21 via a direct interaction is associated with apoptosis and chemoresistance in MIA PaCa-2 pancreatic cancer cells

Archives of Medical Research

Volumn 42, Issue 1, 2011, Pages 8-14

  Dong, Jie ^a   Zhao, Yu Pei ^a,b   Zhou, Li ^a   Zhang, Tai Ping ^a   Chen, Ge ^a  

^a PEKING UNION MEDICAL COLLEGE HOSPITAL   (China)

^b INSTITUTE OF BASIC MEDICAL SCIENCES   (China)

Author keywords

Apoptosis; Bcl 2; Chemosensitivity; MiR 21; Pancreatic cancer; Proliferation

Indexed keywords

CASPASE 3; GEMCITABINE; MICRORNA 21; PROTEIN BAX;

APOPTOSIS; ARTICLE; CANCER CELL; CELL ACTIVITY; CELL PROLIFERATION; CHEMOSENSITIVITY; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PANCREAS CANCER; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN RNA BINDING; REGULATORY MECHANISM; UPREGULATION;

ANIMALS; ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE, TUMOR; CELL PROLIFERATION; DEOXYCYTIDINE; DRUG RESISTANCE, NEOPLASM; HUMANS; MICRORNAS; PANCREATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-BCL-2; UP-REGULATION;

EID: 79952075732     PISSN: 01884409     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.arcmed.2011.01.006     Document Type: Article

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