-
1
-
-
0035254642
-
Therapeutic targets of radiotherapy
-
Brown JM: Therapeutic targets of radiotherapy Int J Radiat Oncol Biol Phys 49: 319-326, 2001.
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.49
, pp. 319-326
-
-
Brown, J.M.1
-
2
-
-
0034788824
-
Radiation response modification following molecular inhibition of epidermal growth factor receptor signaling
-
Harari PM and Huang SM: Radiation response modification following molecular inhibition of epidermal growth factor receptor signaling Semin Radiat Oncol 11: 281-289, 2001.
-
(2001)
Semin Radiat Oncol
, vol.11
, pp. 281-289
-
-
Harari, P.M.1
Huang, S.M.2
-
3
-
-
0032815618
-
Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death
-
Dent P, Reardon DB, Park JS, Bowers G, Logsdon C, Valerie K and Schmidt-Ullrich R: Radiation-induced release of transforming growth factor alpha activates the epidermal growth factor receptor and mitogen-activated protein kinase pathway in carcinoma cells, leading to increased proliferation and protection from radiation-induced cell death. Mol Biol Cell 10: 2493-2506, 1999.
-
(1999)
Mol Biol Cell
, vol.10
, pp. 2493-2506
-
-
Dent, P.1
Reardon, D.B.2
Park, J.S.3
Bowers, G.4
Logsdon, C.5
Valerie, K.6
Schmidt-Ullrich, R.7
-
4
-
-
0037030519
-
Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells
-
Contessa JN, Hampton J and Lammering G: Ionizing radiation activates Erb-B receptor dependent Akt and p70 S6 kinase signaling in carcinoma cells. Oncogene 21: 4032-4041, 2002.
-
(2002)
Oncogene
, vol.21
, pp. 4032-4041
-
-
Contessa, J.N.1
Hampton, J.2
Lammering, G.3
-
5
-
-
0034029550
-
Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest
-
Hagan M, Wang L and Hanley JR: Ionizing radiation-induced mitogen-activated protein (MAP) kinase activation in DU145 prostate carcinoma cells: MAP kinase inhibition enhances radiation-induced cell killing and G2/M-phase arrest. Radiat Res 153: 371-383, 2000.
-
(2000)
Radiat Res
, vol.153
, pp. 371-383
-
-
Hagan, M.1
Wang, L.2
Hanley, J.R.3
-
6
-
-
0141757460
-
MAPK pathways in radiation responses
-
Dent P, Yacoub A and Fisher PB: MAPK pathways in radiation responses Oncogene 22: 5885-5896, 2003.
-
(2003)
Oncogene
, vol.22
, pp. 5885-5896
-
-
Dent, P.1
Yacoub, A.2
Fisher, P.B.3
-
7
-
-
0032719534
-
Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas
-
Akimoto T, Hunter NR and Buchmiller L: Inverse relationship between epidermal growth factor receptor expression and radiocurability of murine carcinomas. Clin Cancer Res 5: 2884-2890, 1999
-
(1999)
Clin Cancer Res
, vol.5
, pp. 2884-2890
-
-
Akimoto, T.1
Hunter, N.R.2
Buchmiller, L.3
-
8
-
-
0033561522
-
Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck
-
Huang SM, Bock JM and Harari PM: Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck. Cancer Res 59: 1935-1940, 1999
-
(1999)
Cancer Res
, vol.59
, pp. 1935-1940
-
-
Huang, S.M.1
Bock, J.M.2
Harari, P.M.3
-
9
-
-
0033966576
-
In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody
-
Milas L, Mason K and Hunter N: In vivo enhancement of tumor radioresponse by C225 antiepidermal growth factor receptor antibody. Clin Cancer Res 6: 701-708, 2000.
-
(2000)
Clin Cancer Res
, vol.6
, pp. 701-708
-
-
Milas, L.1
Mason, K.2
Hunter, N.3
-
10
-
-
0030772168
-
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation
-
Schmidt-Ullrich RK, Mikkelsen RB and Dent P: Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation. Oncogene 15: 1191-1197, 1997.
-
(1997)
Oncogene
, vol.15
, pp. 1191-1197
-
-
Schmidt-Ullrich, R.K.1
Mikkelsen, R.B.2
Dent, P.3
-
11
-
-
0037145061
-
Ligand-induced, receptor-mediated dimerization and activation of EGF receptor
-
Schlessinger J: Ligand-induced, receptor-mediated dimerization and activation of EGF receptor. Cell 110: 669-672, 2002.
-
(2002)
Cell
, vol.110
, pp. 669-672
-
-
Schlessinger, J.1
-
12
-
-
10744230127
-
An open-and-shut case? Recent insights into the activation of EGF/ERBB receptors
-
Burgess AW, Cho HS and Eigenbrot C: An open-and-shut case? Recent insights into the activation of EGF/ERBB receptors. Mol Cell 12: 541-552, 2003.
-
(2003)
Mol Cell
, vol.12
, pp. 541-552
-
-
Burgess, A.W.1
Cho, H.S.2
Eigenbrot, C.3
-
13
-
-
0037115674
-
Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma
-
Ang KK, Berkey BA and Tu X: Impact of epidermal growth factor receptor expression on survival and pattern of relapse in patients with advanced head and neck carcinoma. Cancer Res 62: 7350-7356, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 7350-7356
-
-
Ang, K.K.1
Berkey, B.A.2
Tu, X.3
-
14
-
-
2442541387
-
Selective inhibition of survival signal transduction pathways enhanced radiosensitivity in human esophageal cancer cell lines in vitro
-
Akimoto T, Nonaka T and Harashima K: Selective inhibition of survival signal transduction pathways enhanced radiosensitivity in human esophageal cancer cell lines in vitro. Anticancer Res 24(2B): 811-819, 2004.
-
(2004)
Anticancer Res
, vol.24
, Issue.2 B
, pp. 811-819
-
-
Akimoto, T.1
Nonaka, T.2
Harashima, K.3
-
15
-
-
0035341495
-
Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: Possible involvement of inhibition of survival signal transduction pathways
-
Akimoto T, Nonaka T and Ishikawa H: Genistein, a tyrosine kinase inhibitor, enhanced radiosensitivity in human esophageal cancer cell lines in vitro: Possible involvement of inhibition of survival signal transduction pathways. Int J Radiat Oncol Biol Phys 50: 195-201, 2001.
-
(2001)
Int J Radiat Oncol Biol Phys
, vol.50
, pp. 195-201
-
-
Akimoto, T.1
Nonaka, T.2
Ishikawa, H.3
-
16
-
-
0033561522
-
Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck
-
Huang SM, Bock JM and Harari PM: Epidermal growth factor receptor blockade with C225 modulates proliferation, apoptosis, and radiosensitivity in squamous cell carcinomas of the head and neck. Cancer Res 59: 1935-1940, 1999.
-
(1999)
Cancer Res
, vol.59
, pp. 1935-1940
-
-
Huang, S.M.1
Bock, J.M.2
Harari, P.M.3
-
17
-
-
0041563993
-
The epidermal growth factor receptor mediates radioresistance
-
Liang K, Ang KK and Milas L: The epidermal growth factor receptor mediates radioresistance. Int J Radiat Oncol Biol Phys 57: 246-254, 2003.
-
(2003)
Int J Radiat Oncol Biol Phys
, vol.57
, pp. 246-254
-
-
Liang, K.1
Ang, K.K.2
Milas, L.3
-
18
-
-
1242315585
-
Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells
-
Bonner JA, Buchsbaum DJ and Rogers BE: Adenoviral vector-mediated augmentation of epidermal growth factor receptor (EGFr) enhances the radiosensitization properties of anti-EGFr treatment in prostate cancer cells. Int J Radiat Oncol Biol Phys 58: 950-958, 2004.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.58
, pp. 950-958
-
-
Bonner, J.A.1
Buchsbaum, D.J.2
Rogers, B.E.3
-
19
-
-
1242289115
-
Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression
-
Bonner JA, Buchsbaum DJ and Russo SM: Anti-EGFR-mediated radiosensitization as a result of augmented EGFR expression. Int J Radiat Oncol Biol Phys 59(2 Suppl): 2-10, 2004.
-
(2004)
Int J Radiat Oncol Biol Phys
, vol.59
, Issue.2 SUPPL.
, pp. 2-10
-
-
Bonner, J.A.1
Buchsbaum, D.J.2
Russo, S.M.3
-
20
-
-
34447299688
-
Investigation of the dimerization of proteins from the epidermal growth factor receptor family by single wavelength fluorescence cross-correlation spectroscopy
-
Liu P, Sudhaharan T and Koh RM: Investigation of the dimerization of proteins from the epidermal growth factor receptor family by single wavelength fluorescence cross-correlation spectroscopy. Biophys J 93: 684-698, 2007.
-
(2007)
Biophys J
, vol.93
, pp. 684-698
-
-
Liu, P.1
Sudhaharan, T.2
Koh, R.M.3
-
21
-
-
0033590602
-
Augmentation of a humanized anti-HER2 mAb 4D5 induced growth inhibition by a human mouse chimeric anti-EGF receptor mAb C225
-
Ye D, Mendelsohn J and Fan Z: Augmentation of a humanized anti-HER2 mAb 4D5 induced growth inhibition by a human mouse chimeric anti-EGF receptor mAb C225. Oncogene 18: 731-738, 1999.
-
(1999)
Oncogene
, vol.18
, pp. 731-738
-
-
Ye, D.1
Mendelsohn, J.2
Fan, Z.3
-
22
-
-
0033605560
-
ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors
-
Worthylake R, Opresko LK and Wiley HS: ErbB-2 amplification inhibits down-regulation and induces constitutive activation of both ErbB-2 and epidermal growth factor receptors. J Biol Chem 274: 8865-8874, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 8865-8874
-
-
Worthylake, R.1
Opresko, L.K.2
Wiley, H.S.3
-
23
-
-
33748300698
-
Enhancement of radiosensitivity by dual inhibition of the HER family with ZD1839 (Iressa) and trastuzumab (Herceptin)
-
Fukutome M, Maebayashi K and Nasu S: Enhancement of radiosensitivity by dual inhibition of the HER family with ZD1839 (Iressa) and trastuzumab (Herceptin). Int J Radiat Oncol Biol Phys 66: 528-536, 2006.
-
(2006)
Int J Radiat Oncol Biol Phys
, vol.66
, pp. 528-536
-
-
Fukutome, M.1
Maebayashi, K.2
Nasu, S.3
-
24
-
-
8744228288
-
Active and inactive conformations of the epidermal growth factor receptor
-
Ferguson KM: Active and inactive conformations of the epidermal growth factor receptor. Biochem Soc Trans 32(Pt 5): 742-745, 2004.
-
(2004)
Biochem Soc Trans
, vol.32
, Issue.PART 5
, pp. 742-745
-
-
Ferguson, K.M.1
-
25
-
-
0037139359
-
Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene
-
Johns TG, Stockert E and Ritter G: Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene. Int J Cancer 98: 398-408, 2002.
-
(2002)
Int J Cancer
, vol.98
, pp. 398-408
-
-
Johns, T.G.1
Stockert, E.2
Ritter, G.3
-
26
-
-
8744228288
-
Active and inactive conformations of the epidermal growth factor receptor
-
Ferguson KM: Active and inactive conformations of the epidermal growth factor receptor. Biochem Soc Trans 32(Pt 5): 742-745, 2004.
-
(2004)
Biochem Soc Trans
, vol.32
, Issue.PART 5
, pp. 742-745
-
-
Ferguson, K.M.1
-
27
-
-
62649134382
-
Interaction of antibodies with ErbB receptor extracellular regions
-
Schmitz KR and Ferguson KM: Interaction of antibodies with ErbB receptor extracellular regions. Exp Cell Res 315: 659-670, 2009.
-
(2009)
Exp Cell Res
, vol.315
, pp. 659-670
-
-
Schmitz, K.R.1
Ferguson, K.M.2
-
28
-
-
17444403242
-
Structural basis for inhibition of the epidermal growth factor receptor by cetuximab
-
Li S, Schmitz KR and Jeffrey PD: Structural basis for inhibition of the epidermal growth factor receptor by cetuximab. Cancer Cell 7: 301-311, 2005.
-
(2005)
Cancer Cell
, vol.7
, pp. 301-311
-
-
Li, S.1
Schmitz, K.R.2
Jeffrey, P.D.3
-
29
-
-
18144426053
-
The antitumor monoclonal antibody 806 recognizes a high-mannose form of the EGF receptor that reaches the cell surface when cells overexpress the receptor
-
Johns TG, Mellman I and Cartwright GA: The antitumor monoclonal antibody 806 recognizes a high-mannose form of the EGF receptor that reaches the cell surface when cells overexpress the receptor. FASEB J 19: 780-782, 2005.
-
(2005)
FASEB J
, vol.19
, pp. 780-782
-
-
Johns, T.G.1
Mellman, I.2
Cartwright, G.A.3
-
30
-
-
55449102296
-
All EGF (ErbB) receptors have preformed homo- and heterodimeric structures in living cells
-
Tao RH and Maruyama IN: All EGF (ErbB) receptors have preformed homo- and heterodimeric structures in living cells. J Cell Sci 121(Pt 19): 3207-3217, 2008.
-
(2008)
J Cell Sci
, vol.121
, Issue.PART 19
, pp. 3207-3217
-
-
Tao, R.H.1
Maruyama, I.N.2
-
31
-
-
18644386251
-
Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains
-
Ogiso H, Ishitani R and Nureki O: Crystal structure of the complex of human epidermal growth factor and receptor extracellular domains. Cell 110: 775-787, 2002.
-
(2002)
Cell
, vol.110
, pp. 775-787
-
-
Ogiso, H.1
Ishitani, R.2
Nureki, O.3
-
32
-
-
0037291226
-
The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors
-
Garrett TP, McKern NM and Lou M: The crystal structure of a truncated ErbB2 ectodomain reveals an active conformation, poised to interact with other ErbB receptors. Mol Cell 11: 495-505, 2003.
-
(2003)
Mol Cell
, vol.11
, pp. 495-505
-
-
Garrett, T.P.1
McKern, N.M.2
Lou, M.3
-
33
-
-
0041923793
-
Role of extracellular subdomains of p185c-neu and the epidermal growth factor receptor in ligand-independent association and transactivation
-
Kumagai T, Katsumata M and Hasegawa A: Role of extracellular subdomains of p185c-neu and the epidermal growth factor receptor in ligand-independent association and transactivation. Proc Natl Acad Sci USA 100: 9220-9225, 2003.
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 9220-9225
-
-
Kumagai, T.1
Katsumata, M.2
Hasegawa, A.3
|