Acetaminophen increases the risk of arsenic-mediated development of hepatic damage in rats by enhancing redox-signaling mechanism

Environmental Toxicology

Volumn 29, Issue 2, 2014, Pages 187-198

  Majhi, Chhaya Rani ^a   Khan, Saleem ^a   Leo, Marie Dennis Marcus ^a   Prawez, Shahid ^a   Kumar, Amit ^a   Sankar, Palanisamy ^a   Telang, Avinash Gopal ^a   Sarkar, Souvendra Nath ^a  

^a INDIAN VETERINARY RESEARCH INSTITUTE   (India)

Author keywords

Acetaminophen; Antioxidants; Arsenic; Liver; Nitric oxide; Reactive oxygen species

Indexed keywords

ACETAMINOPHEN; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INDUCIBLE NITRIC OXIDE SYNTHASE (INOS); REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASES;

AMINO ACIDS; ANTIOXIDANTS; GENE EXPRESSION; LIPIDS; LIVER; NITRIC OXIDE; OXIDATIVE STRESS; OXYGEN; PEPTIDES; RATS; TOXICITY;

ARSENIC;

ALANINE AMINOTRANSFERASE; ARSENIC; ASPARTATE AMINOTRANSFERASE; CATALASE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NITRIC OXIDE; OXYGEN RADICAL; PARACETAMOL; REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE;

ANTIOXIDANT; ARSENIC; DRUG; ENZYME ACTIVITY; LIPID; OXIDATION; REDOX POTENTIAL; RISK FACTOR; TOXICITY;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; LIPID PEROXIDATION; LIVER INJURY; LIVER TOXICITY; MALE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT;

RATTUS;

ACETAMINOPHEN; ANTIOXIDANTS; ARSENIC; LIVER; NITRIC OXIDE; REACTIVE OXYGEN SPECIES;

ACETAMINOPHEN; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ARSENIC; CATALASE; DRUG SYNERGISM; DRUG-INDUCED LIVER INJURY; GENE EXPRESSION REGULATION; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE REDUCTASE; HEPATOCYTES; LIPID PEROXIDATION; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; NITRIC OXIDE SYNTHASE TYPE III; OXIDATION-REDUCTION; RATS; RATS, WISTAR; REACTIVE OXYGEN SPECIES; SUPEROXIDE DISMUTASE; WATER POLLUTANTS, CHEMICAL;

EID: 84891347198     PISSN: 15204081     EISSN: 15227278     Source Type: Journal    
DOI: 10.1002/tox.20785     Document Type: Article

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