Protective action of a hexane crude extract of Pterodon emarginatus fruits against oxidative and nitrosative stress induced by acute exercise in rats

BMC Complementary and Alternative Medicine

Volumn 5, Issue , 2005, Pages

  Paula, Fernanda B A ^a   Gouvêa, Cibele M C P ^a   Alfredo, Patrícia P ^b   Salgado, Ione ^c  

^a Escola de Farmacia e Odontologia de Alfenas   (Brazil)

^b Universidade de Alfenas   (Brazil)

^c UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

[No Author keywords available]

Indexed keywords

3 NITROTYROSINE; CREATINE KINASE; HEXANE; MALONALDEHYDE; NITRITE; PLANT MEDICINAL PRODUCT; PTERODON EMARGINATUS EXTRACT; REAGENT; UNCLASSIFIED DRUG; 3-NITROTYROSINE; ANTIOXIDANT; DRUG DERIVATIVE; LACTIC ACID DERIVATIVE; PLANT EXTRACT; TYROSINE;

ANIMAL EXPERIMENT; ANTIOXIDANT ACTIVITY; ARTICLE; BRAIN; CELL INFILTRATION; CELL PROTECTION; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DRUG DOSE REGIMEN; DRUG SYNTHESIS; ELECTROSTIMULATION; ENZYME ACTIVITY; EXERCISE; FRUIT; HISTOLOGY; INFLAMMATION; LIPID PEROXIDATION; LIVER; MACROPHAGE; MALE; MEDICINAL PLANT; MUSCLE CONTRACTION; MUSCLE INJURY; NONHUMAN; OVEREXERTION; OXIDATIVE STRESS; PTERODON EMARGINATUS; RAT; SKELETAL MUSCLE; STANDARDIZATION; TIBIALIS ANTERIOR MUSCLE; TRADITIONAL MEDICINE; WESTERN BLOTTING; ANIMAL; DRUG EFFECT; EVALUATION; FABACEAE; METABOLISM; PHYSIOLOGY; WISTAR RAT;

ANIMALS; ANTIOXIDANTS; BRAIN; CREATINE KINASE; FABACEAE; FRUIT; LACTATES; LIPID PEROXIDATION; LIVER; MACROPHAGES; MALE; MUSCLE, SKELETAL; NITRITES; OXIDATIVE STRESS; PHYSICAL CONDITIONING, ANIMAL; PLANT EXTRACTS; RATS; RATS, WISTAR; TYROSINE;

EID: 27644500014     PISSN: 14726882     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-5-17     Document Type: Article

References (43)

1. Liu J, Yeo HC, Övervik-Douki E, Hagen T, Doniger SJ, Chyu DW, Brooks GA, Ames BN: Chronically and acutely exercised rats: biomarkers of oxidative stress and endogenous antioxidants. J App Physiol 2000, 89:21-28.
2. Davies KJ, Quintanilha AT, Brooks GA, Packer L: Free radicals and tissue damage produced by exercise. Biochem Biophys Res Commun 1982, 107:1198-1205.
3. Alessio HM, Goldfarb AH: Lipid peroxidation and scavenger enzymes during exercise: adaptive response to training. J Appl Physiol 1988, 64:1333-1336.
4. Sacheck J, Blumberg J: The role of vitamin E and oxidative stress in exercise. Nutrition 2001, 17:809-814.
5. Proske U, Morgan DL: Muscle damage from eccentric exercise: mechanism, mechanical signs, adaptation and clinical applications. J Physiol 2001, 537:333-345.
6. Marzatico F, Pansara O, Bertorelli L, Somenzini L, Della Valle G: Blood free radical antioxidant enzymes and lipid peroxides following long-distance and lactacidemic performances in highly trained aerobic and sprint athletes. J Sports Med Phys Fitness 1997, 37:235-239.
7. Jungersten L, Ambring A, Wall B, Wennmalm A: Both physical fitness and acute exercise regulate nitric oxide formation in healthy humans. J Appl Physiol 1997, 82:760-764.
8. Roberts CK, Barnard RJ, Jasman A, Balon TW: Acute exercise increases nitric oxide synthase activity in skeletal muscle. Am J Physiol 1999, 277:E390-E394.
9. Reid MB: Role of nitric oxide in skeletal muscle: synthesis, distribution and functional importance. Acta Physiol Scand 1998, 162:401-409.
10. Stamler JS, Meissner G: Physiology of Nitric Oxide in Skeletal Muscle. Physiol Rev 2001, 81:209-237.
11. Davies KJ, Goldberg AL: Proteins damaged by oxygen radicals are rapidly degraded in extracts of red blood cells. J Biol Chem 1987, 262:8227-8234.
12. Eiserich JP, Patel RP, O'Donnell VB: Pathophysiology of nitric oxide and related species: free radical reactions and modification of biomolecules. Mol Aspects Med 1998, 19:221-357.
13. Gunther MR, His LC, Curtis JF, Gierse JK, Marnett LJ, Eling TE, Mason RP: Nitric oxide trapping of the tyrosyl radical of prostaglandin H synthase-2 leads to tyrosine iminoxyl radical and nitrotyrosine formation. J Biol Chem 1997, 272:17086-17090.
14. Hirota S, Takahama U, Ly TN, Yamauchi R: Quercetin-dependent inhibition of nitration induced by peroxidase/H2O2/nitrite systems in human saliva and characterization of an oxidation product of quercetin formed during the inhibition. J Agric Food Chem 2005, 53:3265-3272.
15. Correa MP: Dicionário de plantas úteis do Brasil e das exóticas cultivadas Ministério da Agricultura. Rio de Janeiro: Instituto Brasileiro de Desenvolvimento Florestal; 1984.
16. Mors WB, dos Santos Filho MF, Monteiro HJ, Gilbert B: Chomoprophylactic agent in Schistosomiasis: 14,15-epoxygeranylgeraniol. Science 1967, 157:950-951.
17. Nunan EA, Carvalho MG, Piló-Veloso D, Turchetti-Maia RMM, Ferreira-Alves DL: Furane diterpenes with anti- and pro-inflamatory activity. Braz J Med Biol Res 1982, 15:450.
18. Duarte ID, Ferreira-Alves DL, Veloso DP, Nakamura-Craig M: Evidence of the involvement of biogenic amines in the antinociceptive effect of vouacapan extracted from Pterodon polygalaeflorus Benth. J Ethnopharmcol 1996, 55: 13-18.
19. Mahjan JR, Monteiro MB: New diterpenoids from Pterodon emarginatus Vog. Anais Acad Bras Ciênc 1970, 42:103-107.
20. Carvalho JC, Sertié JA, Barbosa MV, Patrício KC, Caputo LR, Sarti SJ, Ferreira LP, Bastos JK: Anti-inflammatory activity of the crude extract from the fruits of Pterodon emarginatus Vog. J Ethnopharmacol 1999, 64:127-133.
21. Matsuura T, Ikata T, Takata S, Kashiwaguchi S, Niwa M, Sogabe T, Koga K: Effect of weight bearing on recovery from nerve injury in skeletal muscle. J Appl Physiol 2001, 91:2334-2341.
22. Moss DW: Clinical Enzymology. In Tietz Textbook of Clinical Chemistry 3rd edition. Edited by: Burtis CA, Ashwood ER. WB: Saunders Company; 1999:617-721.
23. 2. J Free Rad Biol Med 1985, 1:43-49.
24. Scuro LS, Simioni PU, Gabriel DL, Saviani EE, Modolo, LV, Tamashiro WMSC, Salgado I: Supression of nitric oxide production in mouse macrophage by soybean flavonoids accumulated in response to nitroprusside and fungal eliciation. BMC Biochem 2004, 5:5-12.
25. Bradford MM: A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Bioch 1976, 72:248-254.
26. Kanski J, Alterman MA, Schöneich C: Proteomic identification of age-dependent protein nitration in rat skeletal muscle. Free Radic Biol Med 2003, 35:1229-1239.
27. Pizza FX, Koh TJ, Mcgregor SJ, Brooks SV: Muscle inflammatory cells after passive stretches, isometric contractions, and lengthening contractions. J Appl Physiol 2002, 92:1873-1878.
28. Clarkson PM, Tremblay I: Exercise-induced muscle damage, repair, and adaptation in humans. J Appl Physiol 1988, 65:1-6.
29. Sacheck JM, Millbury PE, Cannon JG, Roubenoff R, Blumberg JB: Effect of vitamin e and eccentric exercise on selected biomarkers of oxidative stress in young and elderly men. Free Rad Biol Med 2003, 34:1575-1588.
30. Salminen A, Vihko V: Lipid peroxidation in exercise myopathy. Exp Mol Pathol 1983, 38:380-388.
31. Lovlin R, Cottle W, Pyke I, Kavanagh M, Belcastrom AN: Are indices of free radical damage related to exercise intensity? Eur J Appl Physiol Occup Physiol 1987, 56:313-316.
32. Halliwell B, Gutteridge JMC: Free Radicals in Biology and Medicine Oxford: Clarendon Press; 1989.
33. Kayatekin BM, Gonenc S, Acikgoz O, Uysal N, Dayi A: Effects of sprint exercise on oxidative stress in skeletal muscle and liver. Eur J Appl Physiol 2002, 87:141-144.
34. Reiser PJ, Kline WO, Vaghy PL: Induction of neuronal type nitric oxide synthase in skeletal muscle by chronic electrical stimulation in vivo. J App Physiol 1997, 82:1250-1255.
35. Slater M, Knowles RG, Moncada S: Widespread tissue distribution, species distribution and changes in activity of Ca(21)-dependent and Ca(21)-independent nitric oxide synthases. FEBS Lett 1991, 291:145-149.
36. Moncada S, Higgs A: The L-arginine-nitric oxide pathway. N Engl J Med 1993, 329:2002-2012.
37. Stull M, Wehling M: Mechanical loading regulates NOS expression and activity in developing and adult skeletal muscle. Am J Physiol 1998, 275:C260-C266.
38. Giulivi C, Poderoso JJ, Boveris A: Production of nitric oxide by mitochondria. J Biol Chem 1998, 273:11038-11043.
39. Ng TB, Liu F, Wang ZT: Antioxidant activity of natural products from plants. Life Sci 2000, 66:709-723.
40. Noguchi N, Niki E: Phenolic antioxidants: a rationale for design and evaluation of novel antioxidant drug for atherosclerosis. Free Rad Biol Med 2000, 28:1538-1546.
41. Di Mascio PD, Medeiros MHG, Sies H, Bertolotti S, Braslavsky SE, Piló Veloso D, Sales BHLN, Magalhães E, Braz-Filho R, Bechara EJH: Quenching of singlet molecular oxygen by natural furan diterpenes. J Photochem Photobiol B: Biology 1997, 38:169-173.
42. Lee KJ: Protective effect of vegetable extracts on oxidative stress in brain of mice administered with NMDA. Food Res Int 2002, 35:55-63.
43. Auvin S, Auget M, Navet E, Harnett JJ, Viossat I, Schulz J, Bigg D, Chabrier Pierre-E: Novel inhibitors of neuronal nitric oxide sythase with potent antioxidant properties. Bioorg Med Chem Let 2003, 13:209-212.