메뉴 건너뛰기




Volumn 18, Issue 4, 2013, Pages 595-611

The clinicopathological significance of lamin A/C, lamin B1 and lamin B receptor mRNA expression in human breast cancer

Author keywords

Ageing; Breast cancer; Cell cycle; Cell senescence; Chromosomal instability; DNA repair; Lamin A C; Lamin B; Lamin B receptor; qPCR

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; ESTROGEN; LAMIN; LAMIN A; LAMIN B RECEPTOR; LAMIN B1; LAMIN C; MESSENGER RNA; UNCLASSIFIED DRUG;

EID: 84891346537     PISSN: 14258153     EISSN: 16891392     Source Type: Journal    
DOI: 10.2478/s11658-013-0109-9     Document Type: Article
Times cited : (82)

References (48)
  • 1
    • 33847342966 scopus 로고    scopus 로고
    • The nuclear lamina. Both a structural framework and a platform for genome organization
    • Bridger, J. M., Foeger, N., Kill, I. R. and Herrmann, H. The nuclear lamina. Both a structural framework and a platform for genome organization. FEBS J. 274 (2007) 1354-1361.
    • (2007) FEBS J , vol.274 , pp. 1354-1361
    • Bridger, J.M.1    Foeger, N.2    Kill, I.R.3    Herrmann, H.4
  • 3
    • 33847345531 scopus 로고    scopus 로고
    • Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression
    • Malhas, A., Lee, C. F., Sanders, R., Saunders, N. J. and Vaux, D. J. Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression. J. Cell Biol. 176 (2007) 593-603. DOI: 10. 1083/jcb. 200607054.
    • (2007) J. Cell Biol. , vol.176 , pp. 593-603
    • Malhas, A.1    Lee, C.F.2    Sanders, R.3    Saunders, N.J.4    Vaux, D.J.5
  • 4
    • 0027416334 scopus 로고
    • Internal lamin structures within G1 nuclei of human dermal fibroblasts
    • Bridger, J. M., Kill, I. R., O'Farrell, M. and Hutchison, C. J. Internal lamin structures within G1 nuclei of human dermal fibroblasts. J. Cell Sci. 104 (1993) 297-306.
    • (1993) J. Cell Sci. , vol.104 , pp. 297-306
    • Bridger, J.M.1    Kill, I.R.2    O'Farrell, M.3    Hutchison, C.J.4
  • 5
    • 0026478894 scopus 로고
    • Pathway of incorporation of microinjected lamin A into the nuclear envelope
    • Goldman, A. E., Moir, R. D., Montag-Lowy, M., Stewart, M. and Goldman, R. D. Pathway of incorporation of microinjected lamin A into the nuclear envelope. J. Cell Biol. 119 (1992) 725-735.
    • (1992) J. Cell Biol. , vol.119 , pp. 725-735
    • Goldman, A.E.1    Moir, R.D.2    Montag-Lowy, M.3    Stewart, M.4    Goldman, R.D.5
  • 7
    • 84872595364 scopus 로고    scopus 로고
    • Mouse models of laminopathies
    • Zhang, H., Kieckhaefer, J. E. and Cao, K. Mouse models of laminopathies. Aging Cell12 (2013) 2-10. DOI: 10. 1111/acel. 12021.
    • (2013) Aging Cell , vol.12 , pp. 2-10
    • Zhang, H.1    Kieckhaefer, J.E.2    Cao, K.3
  • 9
    • 70449348833 scopus 로고    scopus 로고
    • The nuclear envelopathies and human diseases
    • Chi, Y. H., Chen, Z. J. and Jeang, K. T. The nuclear envelopathies and human diseases. J. Biomed. Sci. 16 (2009) 96. DOI: 10. 1186/1423-0127-16-96.
    • (2009) J. Biomed. Sci. , vol.16 , pp. 96
    • Chi, Y.H.1    Chen, Z.J.2    Jeang, K.T.3
  • 10
    • 84859589311 scopus 로고    scopus 로고
    • Lamin A/C protein is overexpressed in tissue-invading prostate cancer and promotes prostate cancer cell growth, migration and invasion through the PI3K/AKT/PTEN pathway
    • Kong, L., Schafer, G., Bu, H., Zhang, Y. and Klocker, H. Lamin A/C protein is overexpressed in tissue-invading prostate cancer and promotes prostate cancer cell growth, migration and invasion through the PI3K/AKT/PTEN pathway. Carcinogenesis33 (2012) 751-759. DOI: 10. 1093/carcin/bgs022.
    • (2012) Carcinogenesis , vol.33 , pp. 751-759
    • Kong, L.1    Schafer, G.2    Bu, H.3    Zhang, Y.4    Klocker, H.5
  • 11
    • 84862777747 scopus 로고    scopus 로고
    • Chromosomal regions associated with prostate cancer risk localize to lamin B-deficient microdomains and exhibit reduced gene transcription
    • Helfand, B. T., Wang, Y., Pfleghaar, K., Shimi, T., Taimen, P. and Shumaker, D. K. Chromosomal regions associated with prostate cancer risk localize to lamin B-deficient microdomains and exhibit reduced gene transcription. J. Pathol. 226 (2012) 735-745. DOI: 10. 1002/path. 3033.
    • (2012) J. Pathol. , vol.226 , pp. 735-745
    • Helfand, B.T.1    Wang, Y.2    Pfleghaar, K.3    Shimi, T.4    Taimen, P.5    Shumaker, D.K.6
  • 12
    • 79956126873 scopus 로고    scopus 로고
    • Proteomics of hepatocellular carcinoma in Chinese patients
    • Luk, J. M. and Liu, A. M. Proteomics of hepatocellular carcinoma in Chinese patients. OMICS15 (2011) 261-266. DOI: 10. 1089/omi. 2010. 0099.
    • (2011) Omics , vol.15 , pp. 261-266
    • Luk, J.M.1    Liu, A.M.2
  • 13
    • 70049111751 scopus 로고    scopus 로고
    • The mRNA expression of SETD2 in human breast cancer: correlation with clinico-pathological parameters
    • Al Sarakbi, W., Sasi, W., Jiang, W. G., Roberts, T., Newbold, R. F. and Mokbel, K. The mRNA expression of SETD2 in human breast cancer: correlation with clinico-pathological parameters. BMC Cancer9 (2009) 290. DOI: 10. 1186/1471-2407-9-290.
    • (2009) BMC Cancer , vol.9 , pp. 290
    • Al Sarakbi, W.1    Sasi, W.2    Jiang, W.G.3    Roberts, T.4    Newbold, R.F.5    Mokbel, K.6
  • 14
    • 33845943560 scopus 로고    scopus 로고
    • hTERT mRNA expression is associated with a poor clinical outcome in human breast cancer
    • Elkak, A., Mokbel, R., Wilson, C., Jiang, W. G., Newbold, R. F. and Mokbel, K. hTERT mRNA expression is associated with a poor clinical outcome in human breast cancer. Anticancer Res. 26 (2006) 4901-4904.
    • (2006) Anticancer Res. , vol.26 , pp. 4901-4904
    • Elkak, A.1    Mokbel, R.2    Wilson, C.3    Jiang, W.G.4    Newbold, R.F.5    Mokbel, K.6
  • 15
    • 84863394376 scopus 로고    scopus 로고
    • The mRNA expression of DAP3 in human breast cancer: correlation with clinicopathological parameters
    • Wazir, U., Jiang, W. G., Sharma, A. K. and Mokbel, K. The mRNA expression of DAP3 in human breast cancer: correlation with clinicopathological parameters. Anticancer Res. 32 (2012) 671-674.
    • (2012) Anticancer Res. , vol.32 , pp. 671-674
    • Wazir, U.1    Jiang, W.G.2    Sharma, A.K.3    Mokbel, K.4
  • 16
    • 0347594125 scopus 로고    scopus 로고
    • Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers
    • Jiang, W. G., Watkins, G., Lane, J., Cunnick, G. H., Douglas-Jones, A., Mokbel, K. and Mansel, R. E. Prognostic value of rho GTPases and rho guanine nucleotide dissociation inhibitors in human breast cancers. Clin. Cancer Res. 9 (2003) 6432-6440.
    • (2003) Clin. Cancer Res. , vol.9 , pp. 6432-6440
    • Jiang, W.G.1    Watkins, G.2    Lane, J.3    Cunnick, G.H.4    Douglas-Jones, A.5    Mokbel, K.6    Mansel, R.E.7
  • 17
    • 0027257461 scopus 로고
    • Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C
    • Lin, F. and Worman, H. J. Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C. J. Biol. Chem. 268 (1993) 16321-16326.
    • (1993) J. Biol. Chem. , vol.268 , pp. 16321-16326
    • Lin, F.1    Worman, H.J.2
  • 19
    • 79952555799 scopus 로고    scopus 로고
    • Laminopathies and lamin-associated signaling pathways
    • Maraldi, N. M., Capanni, C., Cenni, V., Fini, M. and Lattanzi, G. Laminopathies and lamin-associated signaling pathways. J. Cell Biochem. 112 (2011) 979-992. DOI: 10. 1002/jcb. 22992.
    • (2011) J. Cell Biochem , vol.112 , pp. 979-992
    • Maraldi, N.M.1    Capanni, C.2    Cenni, V.3    Fini, M.4    Lattanzi, G.5
  • 21
    • 79959776029 scopus 로고    scopus 로고
    • Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells
    • Cao, K., Graziotto, J. J., Blair, C. D., Mazzulli, J. R., Erdos, M. R., Krainc, D. and Collins, F. S. Rapamycin reverses cellular phenotypes and enhances mutant protein clearance in Hutchinson-Gilford progeria syndrome cells. Sci. Transl. Med. 3 (2011) 89ra58. DOI: 10. 1126/scitranslmed. 3002346.
    • (2011) Sci. Transl. Med. , vol.3
    • Cao, K.1    Graziotto, J.J.2    Blair, C.D.3    Mazzulli, J.R.4    Erdos, M.R.5    Krainc, D.6    Collins, F.S.7
  • 23
    • 0029917273 scopus 로고    scopus 로고
    • Chromosomal assignment of human nuclear envelope protein genes LMNA, LMNB1, and LBR by fluorescence in situ hybridization
    • Wydner, K. L., McNeil, J. A., Lin, F., Worman, H. J. and Lawrence, J. B. Chromosomal assignment of human nuclear envelope protein genes LMNA, LMNB1, and LBR by fluorescence in situ hybridization. Genomics32 (1996) 474-478. DOI: 10. 1006/geno. 1996. 0146.
    • (1996) Genomics , vol.32 , pp. 474-478
    • Wydner, K.L.1    McNeil, J.A.2    Lin, F.3    Worman, H.J.4    Lawrence, J.B.5
  • 24
    • 33645472801 scopus 로고    scopus 로고
    • A mitotic lamin B matrix induced by RanGTP required for spindle assembly
    • Tsai, M. Y., Wang, S., Heidinger, J. M., Shumaker, D. K., Adam, S. A., Goldman, R. D. and Zheng, Y. A mitotic lamin B matrix induced by RanGTP required for spindle assembly. Science311 (2006) 1887-1893. DOI: 10. 1126/science. 1122771.
    • (2006) Science , vol.311 , pp. 1887-1893
    • Tsai, M.Y.1    Wang, S.2    Heidinger, J.M.3    Shumaker, D.K.4    Adam, S.A.5    Goldman, R.D.6    Zheng, Y.7
  • 25
    • 34249788998 scopus 로고    scopus 로고
    • "Laminopathies": a wide spectrum of human diseases
    • Worman, H. J. and Bonne, G. "laminopathies": a wide spectrum of human diseases. Exp. Cell Res. 313 (2007) 2121-2133. DOI: 10. 1016/j. yexcr. 2007. 03. 028.
    • (2007) Exp. Cell Res. , vol.313 , pp. 2121-2133
    • Worman, H.J.1    Bonne, G.2
  • 26
    • 84860864357 scopus 로고    scopus 로고
    • Understanding the roles of nuclear A- and B-type lamins in brain development
    • Young, S. G., Jung, H. J., Coffinier, C. and Fong, L. G. Understanding the roles of nuclear A- and B-type lamins in brain development. J. Biol. Chem. 287 (2012) 16103-16110. DOI: 10. 1074/jbc. R112. 354407.
    • (2012) J. Biol. Chem , vol.287 , pp. 16103-16110
    • Young, S.G.1    Jung, H.J.2    Coffinier, C.3    Fong, L.G.4
  • 28
    • 33746578389 scopus 로고    scopus 로고
    • Sequencing of the reannotated LMNB2 gene reveals novel mutations in patients with acquired partial lipodystrophy
    • Hegele, R. A., Cao, H., Liu, D. M., Costain, G. A., Charlton-Menys, V., Rodger, N. W. and Durrington, P. N. Sequencing of the reannotated LMNB2 gene reveals novel mutations in patients with acquired partial lipodystrophy. Am. J. Hum. Genet. 79 (2006) 383-389. DOI: 10. 1086/505885.
    • (2006) Am. J. Hum. Genet. , vol.79 , pp. 383-389
    • Hegele, R.A.1    Cao, H.2    Liu, D.M.3    Costain, G.A.4    Charlton-Menys, V.5    Rodger, N.W.6    Durrington, P.N.7
  • 29
    • 77958036071 scopus 로고    scopus 로고
    • Lamin B receptor: multi-tasking at the nuclear envelope
    • Olins, A. L., Rhodes, G., Welch, D. B., Zwerger, M. and Olins, D. E. Lamin B receptor: multi-tasking at the nuclear envelope. Nucleus1 (2010) 53-70. DOI: 10. 4161/nucl. 1. 1. 10515.
    • (2010) Nucleus , vol.1 , pp. 53-70
    • Olins, A.L.1    Rhodes, G.2    Welch, D.B.3    Zwerger, M.4    Olins, D.E.5
  • 30
    • 34248171912 scopus 로고    scopus 로고
    • The granulocyte nucleus and lamin B receptor: avoiding the ovoid
    • Hoffmann, K., Sperling, K., Olins, A. L. and Olins, D. E. The granulocyte nucleus and lamin B receptor: avoiding the ovoid. Chromosoma116 (2007) 227-235. DOI: 10. 1007/s00412-007-0094-8.
    • (2007) Chromosoma , vol.116 , pp. 227-235
    • Hoffmann, K.1    Sperling, K.2    Olins, A.L.3    Olins, D.E.4
  • 31
    • 0345535128 scopus 로고    scopus 로고
    • Autosomal recessive hem/greenberg skeletal dysplasia is caused by 3betahydroxysterol delta 14-reductase deficiency due to mutations in the lamin b receptor gene
    • Waterham, H. R., Koster, J., Mooyer, P., Noort Gv, G., Kelley, R. I. and Wilcox, W. R. Autosomal recessive hem/greenberg skeletal dysplasia is caused by 3betahydroxysterol delta 14-reductase deficiency due to mutations in the lamin b receptor gene. Am. J. Hum. Genet. 72 (2003) 1013-1017.
    • (2003) Am. J. Hum. Genet. , vol.72 , pp. 1013-1017
    • Waterham, H.R.1    Koster, J.2    Mooyer, P.3    Noort, G.G.4    Kelley, R.I.5    Wilcox, W.R.6
  • 34
    • 80054706102 scopus 로고    scopus 로고
    • The role of lamin A in cytoskeleton organization in colorectal cancer cells: a proteomic investigation
    • Foster, C. R., Robson, J. L., Simon, W. J., Twigg, J., Cruikshank, D., Wilson, R. G. and Hutchison, C. J. The role of lamin A in cytoskeleton organization in colorectal cancer cells: a proteomic investigation. Nucleus2 (2011) 434-443. DOI: 10. 4161/nucl. 2. 5. 17775.
    • (2011) Nucleus , vol.2 , pp. 434-443
    • Foster, C.R.1    Robson, J.L.2    Simon, W.J.3    Twigg, J.4    Cruikshank, D.5    Wilson, R.G.6    Hutchison, C.J.7
  • 36
    • 36849039867 scopus 로고    scopus 로고
    • Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays
    • Hudson, M. E., Pozdnyakova, I., Haines, K., Mor, G. and Snyder, M. Identification of differentially expressed proteins in ovarian cancer using high-density protein microarrays. Proc. Natl. Acad. Sci. U S A104 (2007) 17494-17499. DOI: 10. 1073/pnas. 0708572104.
    • (2007) Proc. Natl. Acad. Sci. U S A , vol.104 , pp. 17494-17499
    • Hudson, M.E.1    Pozdnyakova, I.2    Haines, K.3    Mor, G.4    Snyder, M.5
  • 37
    • 0026024912 scopus 로고
    • Differential expression of nuclear envelope lamins A and C in human lung cancer cell lines
    • Kaufmann, S. H., Mabry, M., Jasti, R. and Shaper, J. H. Differential expression of nuclear envelope lamins A and C in human lung cancer cell lines. Cancer Res. 51 (1991) 581-586.
    • (1991) Cancer Res. , vol.51 , pp. 581-586
    • Kaufmann, S.H.1    Mabry, M.2    Jasti, R.3    Shaper, J.H.4
  • 41
    • 79953100080 scopus 로고    scopus 로고
    • Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer
    • Capo-chichi, C. D., Cai, K. Q., Simpkins, F., Ganjei-Azar, P., Godwin, A. K. and Xu, X. X. Nuclear envelope structural defects cause chromosomal numerical instability and aneuploidy in ovarian cancer. BMC Med. 9 (2011) 28. DOI: 10. 1186/1741-7015-9-28.
    • (2011) BMC Med. , vol.9 , pp. 28
    • Capo-Chichi, C.D.1    Cai, K.Q.2    Simpkins, F.3    Ganjei-Azar, P.4    Godwin, A.K.5    Xu, X.X.6
  • 42
    • 60149112087 scopus 로고    scopus 로고
    • Reduced expression of lamin A/C correlates with poor histological differentiation and prognosis in primary gastric carcinoma
    • Wu, Z., Wu, L., Weng, D., Xu, D., Geng, J. and Zhao, F. Reduced expression of lamin A/C correlates with poor histological differentiation and prognosis in primary gastric carcinoma. J. Exp. Clin. Cancer Res. 28 (2009) 8. DOI: 10. 1186/1756-9966-28-8.
    • (2009) J. Exp. Clin. Cancer Res. , vol.28 , pp. 8
    • Wu, Z.1    Wu, L.2    Weng, D.3    Xu, D.4    Geng, J.5    Zhao, F.6
  • 43
    • 21244491570 scopus 로고    scopus 로고
    • Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma
    • Agrelo, R., Setien, F., Espada, J., Artiga, M. J., Rodriguez, M., Perez-Rosado, A., Sanchez-Aguilera, A., Fraga, M. F., Piris, M. A. and Esteller, M. Inactivation of the lamin A/C gene by CpG island promoter hypermethylation in hematologic malignancies, and its association with poor survival in nodal diffuse large B-cell lymphoma. J. Clin. Oncol. 23 (2005) 3940-3947. DOI: 10. 1200/JCO. 2005. 11. 650.
    • (2005) J. Clin. Oncol. , vol.23 , pp. 3940-3947
    • Agrelo, R.1    Setien, F.2    Espada, J.3    Artiga, M.J.4    Rodriguez, M.5    Perez-Rosado, A.6    Sanchez-Aguilera, A.7    Fraga, M.F.8    Piris, M.A.9    Esteller, M.10
  • 44
    • 84934440538 scopus 로고    scopus 로고
    • Discovery of lamin B1 and vimentin as circulating biomarkers for early hepatocellular carcinoma
    • Wong, K. F. and Luk, J. M. Discovery of lamin B1 and vimentin as circulating biomarkers for early hepatocellular carcinoma. Methods Mol. Biol. 909 (2012) 295-310. DOI: 10. 1007/978-1-61779-959-4_19.
    • (2012) Methods Mol. Biol. , vol.909 , pp. 295-310
    • Wong, K.F.1    Luk, J.M.2
  • 45
    • 73649104101 scopus 로고    scopus 로고
    • Circulating lamin B1 (LMNB1) biomarker detects early stages of liver cancer in patients
    • Sun, S., Xu, M. Z., Poon, R. T., Day, P. J. and Luk, J. M. Circulating lamin B1 (LMNB1) biomarker detects early stages of liver cancer in patients. J. Proteome Res. 9 (2010) 70-78. DOI: 10. 1021/pr9002118.
    • (2010) J. Proteome Res. , vol.9 , pp. 70-78
    • Sun, S.1    Xu, M.Z.2    Poon, R.T.3    Day, P.J.4    Luk, J.M.5
  • 47
    • 84876231995 scopus 로고    scopus 로고
    • Prognostic and therapeutic implications of mTORC1 and Rictor expression in human breast cancer
    • Wazir, U., Newbold, R. F., Jiang, W. G., Sharma, A. K. and Mokbel, K. Prognostic and therapeutic implications of mTORC1 and Rictor expression in human breast cancer. Oncol. Rep. 29 (2013) 1969-1974. DOI: 10. 3892/or. 2013. 2346.
    • (2013) Oncol. Rep. , vol.29 , pp. 1969-1974
    • Wazir, U.1    Newbold, R.F.2    Jiang, W.G.3    Sharma, A.K.4    Mokbel, K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.