Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression

Journal of Cell Biology

Volumn 176, Issue 5, 2007, Pages 593-603

  Malhas, Ashraf ^a   Lee, Chiu Fan ^b   Sanders, Rebecca ^c,d   Saunders, Nigel J ^a   Vaux, David J ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

LAMIN B; LAMIN C; MEMBRANE PROTEIN;

ANIMAL CELL; ARTICLE; CELL NUCLEUS MEMBRANE; CHROMOSOME 18; CHROMOSOME POSITIONING; FIBROBLAST; GENE EXPRESSION; INTERPHASE; MEMBRANE STABILIZATION; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DEFECT; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROCESSING;

ANIMALS; CELL COMPARTMENTATION; CHROMOSOMES, MAMMALIAN; ENDOPEPTIDASES; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; INTERPHASE; LAMIN TYPE B; MICE; NUCLEAR LAMINA; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTEIN PROCESSING, POST-TRANSLATIONAL;

MURINAE;

EID: 33847345531     PISSN: 00219525     EISSN: 00219525     Source Type: Journal    
DOI: 10.1083/jcb.200607054     Document Type: Article

References (53)

1. Arkonac, B.M., L.C. Foster, N.E. Sibinga, C. Patterson, K. Lai, J.C. Tsai, M.E. Lee, M.A. Perrella, and E. Haber. 1998. Vascular endothelial growth factor induces heparin-binding epidermal growth factor-like growth factor in vascular endothelial cells. J. Biol. Chem. 273:4400-4405.
2. Bergo, M.O., G.K. Leung, P. Ambroziak, J.C. Otto, P.J. Casey, A.Q. Gomes, M.C. Seabra, and S.G. Young. 2001. Isoprenylcysteine carboxyl methyltransferase deficiency in mice. J. Biol. Chem. 276:5841-5845.
3. Bickmore, W.A., and A.D. Carothers. 1995. Factors affecting the timing and imprinting of replication on a mammalian chromosome. J. Cell Sci. 108:2801-2809.
4. Boyle, S., S. Gilchrist, J.M. Bridger, N.L. Mahy, J.A. Ellis, and W.A. Bickmore. 2001. The spatial organization of human chromosomes within the nuclei of normal and emerin-mutant cells. Hum. Mol. Genet. 10:211-219.
5. Branco, M.R., and A. Pombo. 2006. Intermingling of chromosome territories in interphase suggests role in translocations and transcription-dependent associations. PLoS Biol. 4:e138.
6. Broers, J.L., C.J. Hutchison, and F.C. Ramaekers. 2004. Laminopathies. J. Pathol. 204:478-488.
7. Cabal, G.G., A. Genovesio, S. Rodriguez-Navarro, C. Zimmer, O. Gadal, A. Lesne, H. Buc, F. Feuerbach-Fournier, J.C. Olivo-Marin, E.C. Hurt, and U. Nehrbass. 2006. SAGA interacting factors confine sub-diffusion of transcribed genes to the nuclear envelope. Nature. 441:770-773.
8. Casolari, J.M., C.R. Brown, S. Komili, J. West, H. Hieronymus, and P.A. Silver. 2004. Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization. Cell. 117:427-439.
9. Chuang, C.H., A.E. Carpenter, B. Fuchsova, T. Johnson, P. de Lanerolle, and A.S. Belmont. 2006. Long-range directional movement of an interphase chromosome site. Curr. Biol. 16:825-831.
10. Cremer, T., and C. Cremer. 2001. Chromosome territories, nuclear architecture and gene regulation in mammalian cells. Nat. Rev. Genet. 2:292-301.
11. Croft, J.A., J.M. Bridger, S. Boyle, P. Perry, P. Teague, and W.A. Bickmore. 1999. Differences in the localization and morphology of chromosomes in the human nucleus. J. Cell Biol. 145:1119-1131.
12. Edelmann, P., H. Bornfleth, D. Zink, T. Cremer, and C. Cremer. 2001. Morphology and dynamics of chromosome territories in living cells. Biochim. Biophys. Acta. 1551:M29-M39.
13. Eriksson, M., W.T. Brown, L.B. Gordon, M.W. Glynn, J. Singer, L. Scott, M.R. Erdos, C.M. Robbins, T.Y. Moses, P. Berglund, et al. 2003. Recurrent de novo point mutations in lamin A cause Hutchinson-Gilford progeria syndrome. Nature. 423:293-298.
14. Fong, L.G., J.K. Ng, J. Lammerding, T.A. Vickers, M. Meta, N. Cote, B. Gavino, X. Qiao, S.Y. Chang, S.R. Young, et al. 2006. Prelamin A and lamin A appear to be dispensable in the nuclear lamina. J. Clin. Invest. 116:743-752.
15. Gilbert, N., S. Gilchrist, and W.A. Bickmore. 2005. Chromatin organization in the mammalian nucleus. Int. Rev. Cytol. 242:283-336.
16. Glynn, M.W., and T.W. Glover. 2005. Incomplete processing of mutant lamin A in Hutchinson-Gilford progeria leads to nuclear abnormalities, which are reversed by farnesyltransferase inhibition. Hum. Mol. Genet. 14:2959-2969.
17. Goldberg, M., A. Harel, M. Brandeis, T. Rechsteiner, T.J. Richmond, A.M. Weiss, and Y. Gruenbaum. 1999. The tail domain of lamin Dm0 binds histones H2A and H2B. Proc. Natl. Acad. Sci. USA. 96:2852-2857.
18. Goldman, R.D., Y. Gruenbaum, R.D. Moir, D.K. Shumaker, and T.P. Spann. 2002. Nuclear lamins: building blocks of nuclear architecture. Genes Dev. 16:533-547.
19. Gruenbaum, Y., A. Margalit, R.D. Goldman, D.K. Shumaker, and K.L. Wilson. 2005. The nuclear lamina comes of age. Nat. Rev. Mol. Cell Biol. 6:21-31.
20. Heun, P., T. Laroche, K. Shimada, P. Furrer, and S.M. Gasser. 2001. Chromosome dynamics in the yeast interphase nucleus. Science. 294:2181-2186.
21. Hewitt, S.L., F.A. High, S.L. Reiner, A.G. Fisher, and M. Merkenschlager. 2004. Nuclear repositioning marks the selective exclusion of lineage-inappropriate transcription factor loci during T helper cell differentiation. Eur. J. Immunol. 34:3604-3613.
22. Hutchison, C.J., and H.J. Worman. 2004. A-type lamins: guardians of the soma? Nat. Cell Biol. 6:1062-1067.
23. Imai, S., S. Nishibayashi, K. Takao, M. Tomifuji, T. Fujino, M. Hasegawa, and T. Takano. 1997. Dissociation of Oct1 from the nuclear peripheral structures induces the cellular aging associated collagenase gene expression. Mol. Biol. Cell. 8:2407-2419.
24. Iwamoto, R., and E. Mekada. 2006. ErbB and HB-EGF signaling in heart development and funciton. Cell Struct. Funct. 31:1-14.
25. Kim, E., P. Ambroziak, J.C. Otto, B. Taylor, M. Ashby, K. Shannon, P.J. Casey, and S.G. Young. 1999. Disruption of the mouse Rce1 gene results in defective Ras processing and mislocalization of Ras within cells. J. Biol. Chem. 274:8383-8390.
26. 2. J. Cell Biol. 113:13-23.
27. T method. Methods. 25:402-408.
28. Mallampalli, M.P., G. Huyer, P. Bendale, M.H. Gelb, and S. Michaelis. 2005. Inhibiting farnesylation reverses the nuclear morphology defect in a HeLa cell model for Hutchinson-Gilford progeria syndrome. Proc. Natl. Acad. Sci. USA. 102:14416-14421.
29. Manders, E.M., A.E. Visser, A. Koppen, W.C. de Leeuw, R. van Liere, G.J. Brakenhoff, and R. van Driel. 2003. Four-dimensional imaging of chromatin dynamics during the assembly of the interphase nucleus. Chromosome Res. 11:537-547.
30. Maske, C.P., M.S. Hollinshead, N.C. Higbee, M.O. Bergo, S.G. Young, and D.J. Vaux. 2003. A carboxyl-terminal interaction of lamin B1 is dependent on the CAAX endoprotease Rce1 and carboxymethylation. J. Cell Biol. 162:1223-1232.
31. Masny, P.S., U. Bengtsson, S. Chung, J.H. Martin, B. van Engelen, S.M. van der Maarel, and S.T. Winokur. 2004. Localization of 4q35.2 to the nuclear periphery: is FSHD a nuclear envelope disease? Hum. Mol. Genet. 13:1857-1871.
32. Mayer, R., A. Brero, J. von Hase, T. Schroeder, T. Cremer, and S. Dietzel. 2005. Common themes and cell type specific variations of higher order chromatin arrangements in the mouse. BMC Cell Biol. 6:44.
33. Meaburn, K.J., N. Levy, D. Toniolo, and J.M. Bridger. 2005. Chromosome positioning is largely unaffected in lymphoblastoid cell lines containing emerin or A-type lamin mutations. Biochem. Soc. Trans. 33:1438-1440.
34. Misteli, T. 2001. Protein dynamics: implications for nuclear architecture and gene expression. Science. 291:843-847.
35. Mounkes, L., S. Kozlov, B. Burke, and C.L. Stewart. 2003. The laminopathies: nuclear structure meets disease. Curr. Opin. Genet. Dev. 13:223-230.
36. Padiath, Q.S., S. Kazumasa, R. Schiffman, H. Asahara, T. Yamada, A. Koeppen, K. Hogan, L.J. Ptacek, and Y.-H. Fu. 2006. Lamin B1 duplications cause autosomal dominant leukodystrophy. Nat. Genet. 38:1114-1123.
37. Parada, L.A., P.G. McQueen, P.J. Munson, and T. Misteli. 2002. Conservation of relative chromosome positioning in normal and cancer cells. Curr. Biol. 12:1692-1697.
38. Parada, L.A., P.G. McQueen, and T. Misteli. 2004. Tissue-specific spatial organization of genomes. Genome Biol. 5:R44.
39. Ralph, S.A., C. Scheidig-Benatar, and A. Scherf. 2005. Antigenic variation in Plasmodium falciparum is associated with movement of var loci between subnuclear locations. Proc. Natl. Acad. Sci. USA. 102:5414-5419.
40. Saal, L.H., C. Troein, J. Vallon-Christersson, S. Gruvberger, A. Borg, and C. Peterson. 2002. BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data. Genome Biol. 3:software0003.1-software0003.6.
41. Shopland, L.S., C.R. Lynch, K.A. Peterson, K. Thornton, N. Kepper, J.V. Hase, S. Stein, S. Vincent, K.R. Molloy, G. Kreth, et al. 2006. Folding and organization of a contiguous chromosome region according to the gene distribution pattern in primary genomic sequence. J. Cell Biol. 174:27-38.
42. Spann, T.P., A.E. Goldman, C. Wang, S. Huang, and R.D. Goldman. 2002. Alteration of nuclear lamin organization inhibits RNA polymerase II-dependent transcription. J. Cell Biol. 156:603-608.
43. Svensson, A.W., P.J. Casey, S.G. Young, and M.O. Bergo. 2005. Genetic and pharmacologic analyses of the role of Icmt in ras membrane association and function. Methods Enzymol. 407:144-159.
44. Taddei, A., G. Van Houwe, F. Hediger, V. Kalck, F. Cubizolles, H. Schober, and S.M. Gasser. 2006. Nuclear pore association confers optimal expression levels for an inducible yeast gene. Nature. 441:774-778.
45. Tanabe, H., K. Kupper, T. Ishida, M. Neusser, and H. Mizusawa. 2005. Inter-and intra-specific gene-density-correlated radial chromosome territory arrangements are conserved in Old World monkeys. Cytogenet. Genome Res. 108:255-261.
46. Taniura, H., C. Glass, and L. Gerace. 1995. A chromatin binding site in the tail domain of nuclear lamins that interacts with core histones. J. Cell Biol. 131:33-44.
47. Varela, I., J. Cadinanos, A.M. Pendas, A. Gutierrez-Fernandez, A.R. Folgueras, L.M. Sanchez, Z. Zhou, F.J. Rodriguez, C.L. Stewart, J.A. Vega, et al. 2005. Accelerated ageing in mice deficient in Zmpste24 protease is linked to p53 signalling activation. Nature. 437:564-568.
48. Vergnes, L., M. Peterfy, M.O. Bergo, S.G. Young, and K. Reue. 2004. Lamin B1 is required for mouse development and nuclear integrity. Proc. Natl. Acad. Sci. USA. 101:10428-10433.
49. Walter, J., L. Schermelleh, M. Cremer, S. Tashiro, and T. Cremer. 2003. Chromosome order in HeLa cells changes during mitosis and early G1, but is stably maintained during subsequent interphase stages. J. Cell Biol. 160:685-697.
50. Worman, H.J., and J.C. Courvalin. 2005. Nuclear envelope, nuclear lamina, and inherited disease. Int. Rev. Cytol. 246:231-279.
51. Yang, S.H., M.O. Bergo, J.I. Toth, X. Qiao, Y. Hu, S. Sandoval, M. Meta, P. Bendale, M.H. Gelb, S.G. Young, and L.G. Fong. 2005. Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson-Gilford progeria syndrome mutation. Proc. Natl. Acad. Sci. USA. 102:10291-10296.
52. Zink, D., T. Cremer, R. Saffrich, R. Fischer, M.F. Trendelenburg, W. Ansorge, and E.H. Stelzer. 1998. Structure and dynamics of human interphase chromosome territories in vivo. Hum. Genet. 102:241-251.
53. Zink, D., M.D. Amaral, A. Englmann, S. Lang, L.A. Clarke, C. Rudolph, F. Alt, K. Luther, C. Braz, N. Sadoni, et al. 2004. Transcription-dependent spatial arrangements of CFTR and adjacent genes in human cell nuclei. J. Cell Biol. 166:815-825.