Bupivacaine-induced cellular entry of QX-314 and its contribution to differential nerve block

British Journal of Pharmacology

Volumn 171, Issue 2, 2014, Pages 438-451

  Brenneis, C ^a   Kistner, K ^c   Puopolo, M ^b,e   Jo, S ^b   Roberson, D P ^a   Sisignano, M ^d   Segal, D ^a   Cobos, E J ^a,f   Wainger, B J ^a   Labocha, S ^d   Ferreiros N ^d   Von Hehn, C ^a   Tran, J ^a   Geisslinger, G ^d   Reeh, P W ^c   Bean, B P ^b   Woolf, C J ^a,b  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

^d UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^e Stony Brook School of Dental Medicine   (United States)

^f UNIVERSITY OF GRANADA   (Spain)

Author keywords

CAP; DRG; nociception; QX 314; sciatic nerve; TRPA1; TRPV1

Indexed keywords

BUPIVACAINE; CALCIUM; LIDOCAINE ETHOBROMIDE; RUTHENIUM RED; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; VANILLOID RECEPTOR 1;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; BIOACCUMULATION; CALCIUM TRANSPORT; CONTROLLED STUDY; DRUG TRANSPORT; EX VIVO STUDY; HETEROLOGOUS EXPRESSION; INTRACELLULAR RECORDING; INTRACELLULAR TRANSPORT; MOTOR NERVE BLOCK; MOUSE; NERVE POTENTIAL; NOCICEPTION; NONHUMAN; PATCH CLAMP TECHNIQUE; PRIORITY JOURNAL; RAT; SCIATIC NERVE; SPINAL GANGLION; WILD TYPE;

CAP; DRG; NOCICEPTION; QX-314; SCIATIC NERVE; TRPA1; TRPV1;

ANESTHETICS, LOCAL; ANIMALS; BEHAVIOR, ANIMAL; BUPIVACAINE; CALCIUM; CELL LINE; FOOT INJURIES; GANGLIA, SPINAL; INJECTIONS; LIDOCAINE; MALE; MICE, KNOCKOUT; NERVE BLOCK; PATCH-CLAMP TECHNIQUES; PERIPHERAL NERVES; PRIMARY CELL CULTURE; RATS; RATS, SPRAGUE-DAWLEY; SCIATIC NERVE; SODIUM CHANNEL BLOCKERS; TRANSIENT RECEPTOR POTENTIAL CHANNELS;

EID: 84891276260     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12466     Document Type: Article

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