-
1
-
-
85028020836
-
Facile and efficient syntheses of novel (S)-and (R)-3-fluoropyrrolidines and 3, 3-difluoropyrrolidine
-
Giardina, G.; Dondio, G.; Grugni, M. Facile and efficient syntheses of novel (S)-and (R)-3-fluoropyrrolidines and 3, 3-difluoropyrrolidine. Synlett 1995, 55-57.
-
(1995)
Synlett
, pp. 55-57
-
-
Giardina, G.1
Dondio, G.2
Grugni, M.3
-
2
-
-
0030834571
-
Development and evaluation of peptide-based prolyl oligo-peptidase inhibitors. Introduction of N-benzyloxycarbonyl-prolyl-3-fluoropyrrolidine as a lead in inhibitor design
-
Goossens, F.; VanHoof, G.; De Meester, I.; Augustyns, K.; Borloo, M.; Tourwe, D.; Haemers, A.; Scharpe, S. Development and evaluation of peptide-based prolyl oligo-peptidase inhibitors. Introduction of N-benzyloxycarbonyl-prolyl-3-fluoropyrrolidine as a lead in inhibitor design. Eur. J. Biochem. 1997, 250, 177-183.
-
(1997)
Eur. J. Biochem
, vol.250
, pp. 177-183
-
-
Goossens, F.1
VanHoof, G.2
De Meester, I.3
Augustyns, K.4
Borloo, M.5
Tourwe, D.6
Haemers, A.7
Scharpe, S.8
-
3
-
-
33745151060
-
(2S, 3S)-3-Amino-4-(3, 3-difluoro-pyrrolidin-1-yl)-N, N-dimethyl-4-oxo-2-(4-[1, 2, 4]triazolo[1, 5-a]-pyridin-6-ylphenyl)bu-tanamide: a selective a-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes
-
Edmondson, S.D.;Mastracchio, A.;Mathvink, R.J.; He, J.; Harper, B.; Park, Y.-J.; Beconi, M.; Di Salvo, J.; Eiermann, G.J.; He, H.; Leiting, B.; Leone, J.F.; Levorse, D.A.; Lyons, K.; Patel, R.A.; Patel, S.B.; Petrov, A.; Scapin, G.; Shang, J.; Roy, R.S.; Smith, A.; Wu, J.K.; Xu, S.; Zhu, B.; Thornberry, N.A.; Weber, A.E. (2S, 3S)-3-Amino-4-(3, 3-difluoro-pyrrolidin-1-yl)-N, N-dimethyl-4-oxo-2-(4-[1, 2, 4]triazolo[1, 5-a]-pyridin-6-ylphenyl)bu-tanamide: a selective a-amino amide dipeptidyl peptidase IV inhibitor for the treatment of type 2 diabetes. J. Med. Chem. 2006, 49, 3614-3627.
-
(2006)
J. Med. Chem
, vol.49
, pp. 3614-3627
-
-
Edmondson, S.D.1
Mastracchio, A.2
Mathvink, R.J.3
He, J.4
Harper, B.5
Park, Y.-J.6
Beconi, M.7
Di Salvo, J.8
Eiermann, G.J.9
He, H.10
Leiting, B.11
Leone, J.F.12
Levorse, D.A.13
Lyons, K.14
Patel, R.A.15
Patel, S.B.16
Petrov, A.17
Scapin, G.18
Shang, J.19
Roy, R.S.20
Smith, A.21
Wu, J.K.22
Xu, S.23
Zhu, B.24
Thornberry, N.A.25
Weber, A.E.26
more..
-
4
-
-
33748319394
-
Discovery of potent, selective, and orally bioavail-able oxadiazole-based dipeptidyl peptidase IV inhibitors
-
Xu, J.; Wei, L.; Mathvink, R.J.; Edmondson, S.D.; Eiermann, G.J.; He, H.; Leone, J.F.; Leiting, B.; Lyons, K.A.; Marsilio, F.; Patel, R.A.; Patel, S.B.; Petrov, A.; Scapin, G.; Wu, J.K.; Thornberry, N.A.; Weber, A.E. Discovery of potent, selective, and orally bioavail-able oxadiazole-based dipeptidyl peptidase IV inhibitors. Bioorg. Med. Chem. Lett. 2006, 16, 5357-5377.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 5357-5377
-
-
Xu, J.1
Wei, L.2
Mathvink, R.J.3
Edmondson, S.D.4
Eiermann, G.J.5
He, H.6
Leone, J.F.7
Leiting, B.8
Lyons, K.A.9
Marsilio, F.10
Patel, R.A.11
Patel, S.B.12
Petrov, A.13
Scapin, G.14
Wu, J.K.15
Thornberry, N.A.16
Weber, A.E.17
-
5
-
-
10744233045
-
Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors
-
Caldwell, C.G.; Chen, P.; He, J.; Parmee, E.R.; Leiting, B.;Marsilio, F.; Patel, R.A.;Wu, J. K.; Eiermann, G.J.; Petrov, A.; He, H.; Lyons, K.A.; Thornberry, N.A.; Weber, A.E. Fluoropyrrolidine amides as dipeptidyl peptidase IV inhibitors. Bioorg. Med. Chem. Lett. 2004, 14, 1265-1268.
-
(2004)
Bioorg. Med. Chem. Lett
, vol.14
, pp. 1265-1268
-
-
Caldwell, C.G.1
Chen, P.2
He, J.3
Parmee, E.R.4
Leiting, B.5
Marsilio, F.6
Patel, R.A.7
Wu, J.K.8
Eiermann, G.J.9
Petrov, A.10
He, H.11
Lyons, K.A.12
Thornberry, N.A.13
Weber, A.E.14
-
6
-
-
25144476018
-
New fluorinated pyrrolidine and azetidine amides as dipeptidyl peptidase inhibitors
-
Hulin, B.; Cagral, S.; Lopaze, M.G.; Van Volkenburg, M.A.; Andrews, K.M.; Parker, J.C. New fluorinated pyrrolidine and azetidine amides as dipeptidyl peptidase inhibitors. Bioorg. Med. Chem. Lett. 2005, 15, 4770-4773.
-
(2005)
Bioorg. Med. Chem. Lett
, vol.15
, pp. 4770-4773
-
-
Hulin, B.1
Cagral, S.2
Lopaze, M.G.3
Van Volkenburg, M.A.4
Andrews, K.M.5
Parker, J.C.6
-
8
-
-
25144487382
-
Lithium aluminum hydride reduction of polyfluorocyclic imides
-
Chaudry, M.T.; Powers, G.A.; Stephens, R.; Tatlow, T.C. Lithium aluminum hydride reduction of polyfluorocyclic imides. J. Chem. Soc. 1964, 874-876.
-
(1964)
J. Chem. Soc
, pp. 874-876
-
-
Chaudry, M.T.1
Powers, G.A.2
Stephens, R.3
Tatlow, T.C.4
-
10
-
-
0037435067
-
Synthesis and structure-activity relationships of 5-amino-6-fluoro-1-[(1R, 2S)-2-fluorocyclopropan-1-yl]-8-methylquinolonecar-boxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)-pyrrolidin-1-yl] substituents
-
Inagaki, H.; Miyauchi, S.; Miyauchi, R.N.; Kawato, H.C.; Ohki, H.; Matsuhashi, N.; Kawakami, K.; Takahashi, H.; Takemura, M. Synthesis and structure-activity relationships of 5-amino-6-fluoro-1-[(1R, 2S)-2-fluorocyclopropan-1-yl]-8-methylquinolonecar-boxylic acid antibacterials having fluorinated 7-[(3R)-3-(1-aminocyclopropan-1-yl)-pyrrolidin-1-yl] substituents. J. Med. Chem. 2003, 46, 1005-1015.
-
(2003)
J. Med. Chem
, vol.46
, pp. 1005-1015
-
-
Inagaki, H.1
Miyauchi, S.2
Miyauchi, R.N.3
Kawato, H.C.4
Ohki, H.5
Matsuhashi, N.6
Kawakami, K.7
Takahashi, H.8
Takemura, M.9
-
11
-
-
0001638637
-
Incorporation of cis-and trans-4-fluoro-l-prolines and hydroxylation of the trans isomer during collagen biosynthesis
-
Gottlieb, A.A.; Fujita, Y.; Undenfriend, S.; Witkop, B. Incorporation of cis-and trans-4-fluoro-l-prolines and hydroxylation of the trans isomer during collagen biosynthesis. Biochemistry 1965, 4, 2507-2513.
-
(1965)
Biochemistry
, vol.4
, pp. 2507-2513
-
-
Gottlieb, A.A.1
Fujita, Y.2
Undenfriend, S.3
Witkop, B.4
-
12
-
-
0017654371
-
Potential inhibitors of collagen biosynthesis. 4, 4-Difluoro-l-proline and 4, 4-dimethyl-dl-proline and their activation by prolyl-1-RNA ligase
-
Shirota, F.N.; Nagasawa, H.T.; Elberling, J.A. Potential inhibitors of collagen biosynthesis. 4, 4-Difluoro-l-proline and 4, 4-dimethyl-dl-proline and their activation by prolyl-1-RNA ligase. J. Med. Chem. 1977, 20, 1176-1181.
-
(1977)
J. Med. Chem
, vol.20
, pp. 1176-1181
-
-
Shirota, F.N.1
Nagasawa, H.T.2
Elberling, J.A.3
-
13
-
-
33846163850
-
Synthesis of (2S)-4, 4-difluoroproline and (2S, 4R)-4-fluoroproline and their derivatives from (S)-aspartic acid
-
Burger, K.; Rudolph, M.; Fehn, S.; Sewald, N. Synthesis of (2S)-4, 4-difluoroproline and (2S, 4R)-4-fluoroproline and their derivatives from (S)-aspartic acid. J. Fluorine Chem. 1994, 66, 87-90.
-
(1994)
J. Fluorine Chem
, vol.66
, pp. 87-90
-
-
Burger, K.1
Rudolph, M.2
Fehn, S.3
Sewald, N.4
-
14
-
-
0032485422
-
Practical synthesis of Boc and Fmoc protected 4-fluoro and 4-difluoroprolines from trans-4-hydroxyproline
-
Demange, L.; Menez, A.; Dugave, C. Practical synthesis of Boc and Fmoc protected 4-fluoro and 4-difluoroprolines from trans-4-hydroxyproline. Tetrahedron Lett. 1998, 39, 1169-1172.
-
(1998)
Tetrahedron Lett
, vol.39
, pp. 1169-1172
-
-
Demange, L.1
Menez, A.2
Dugave, C.3
-
15
-
-
18644382329
-
Simple and efficient syntheses of Boc-and Fmoc-protected 4(R)-and 4(S)-fluoroproline solely from 4(R)-hydroxyproline
-
Doi, M.; Nishi, Y.; Kiritoshi, N.; Iwata, T.; Nago, M.; Nakano, H.; Uchiyama, S.; Nakazawa, T.; Wakamiya, T.; Kobayashi, Y. Simple and efficient syntheses of Boc-and Fmoc-protected 4(R)-and 4(S)-fluoroproline solely from 4(R)-hydroxyproline. Tetrahedron 2002, 58, 8453-8459.
-
(2002)
Tetrahedron
, vol.58
, pp. 8453-8459
-
-
Doi, M.1
Nishi, Y.2
Kiritoshi, N.3
Iwata, T.4
Nago, M.5
Nakano, H.6
Uchiyama, S.7
Nakazawa, T.8
Wakamiya, T.9
Kobayashi, Y.10
-
16
-
-
0028884952
-
δ, ε-Unsaturated β, β-difluoro-a-keto esters: novel synthesis and utility as precursors of β, β-difluoro-a-amino acids
-
Shi, G.Q.; Cai, W.L. δ, ε-Unsaturated β, β-difluoro-a-keto esters: novel synthesis and utility as precursors of β, β-difluoro-a-amino acids. J. Org. Chem. 1985, 60, 6289-6295.
-
(1985)
J. Org. Chem
, vol.60
, pp. 6289-6295
-
-
Shi, G.Q.1
Cai, W.L.2
-
17
-
-
20544453286
-
Proline editing: a divergent strategy for the synthesis of conformationally diverse peptides
-
Thomas, K.M.; Naduthambi, D.; Tririya, G.; Zondlo, N.J. Proline editing: a divergent strategy for the synthesis of conformationally diverse peptides. Org. Lett. 2005, 7, 2397-2400.
-
(2005)
Org. Lett
, vol.7
, pp. 2397-2400
-
-
Thomas, K.M.1
Naduthambi, D.2
Tririya, G.3
Zondlo, N.J.4
-
18
-
-
33644999409
-
First 1, 3-dipolar cycloaddition of azomethine ylides with (E)-ethyl 3-fluoroacrylate: regio-and stereoselective synthesis of enantiopure fluorinated prolines
-
Bonini, B.F.; Boschi, F.; Franchini, M.C.; Fochi, M.; Fini, F.; Mazzanti, A.; Ricci, A. First 1, 3-dipolar cycloaddition of azomethine ylides with (E)-ethyl 3-fluoroacrylate: regio-and stereoselective synthesis of enantiopure fluorinated prolines. Synlett 2006, 543-546.
-
(2006)
Synlett
, pp. 543-546
-
-
Bonini, B.F.1
Boschi, F.2
Franchini, M.C.3
Fochi, M.4
Fini, F.5
Mazzanti, A.6
Ricci, A.7
-
19
-
-
33750861305
-
Divergent chemical syntheses of prolines bearing fluorinated one-carbon units at the 4-position via nucleophilic 5-endo-trig cyclizations
-
Nadano, R.; Iwai, Y.; Mori, T.; Ichikawa, J. Divergent chemical syntheses of prolines bearing fluorinated one-carbon units at the 4-position via nucleophilic 5-endo-trig cyclizations. J. Org. Chem. 2006, 71, 8748-8754.
-
(2006)
J. Org. Chem
, vol.71
, pp. 8748-8754
-
-
Nadano, R.1
Iwai, Y.2
Mori, T.3
Ichikawa, J.4
-
20
-
-
0037040286
-
Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen
-
Di Lullo, G.A.; Sweeney, S.M.; Korkko, J.; Ala-Kokko, L.; San Antonio, J.D. Mapping the ligand-binding sites and disease-associated mutations on the most abundant protein in the human, type I collagen. J. Biol. Chem. 2002, 277, 4223-4231.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 4223-4231
-
-
Di Lullo, G.A.1
Sweeney, S.M.2
Korkko, J.3
Ala-Kokko, L.4
San Antonio, J.D.5
-
21
-
-
0033079679
-
A hyperstable collagen mimic
-
Holmgren, S.K.; Bretscher, L.E.; Taylor, K.M.; Raines, R.T. A hyperstable collagen mimic. Chem. Biol. 1999, 6, 63-70.
-
(1999)
Chem. Biol
, vol.6
, pp. 63-70
-
-
Holmgren, S.K.1
Bretscher, L.E.2
Taylor, K.M.3
Raines, R.T.4
-
22
-
-
0015624009
-
The thermal transition of a non-hydroxylated form of collagen. Evidence for a role for hydroxyproline in stabilizing the triple helix of collagen
-
Berg, R.A.; Prockop, D.J. The thermal transition of a non-hydroxylated form of collagen. Evidence for a role for hydroxyproline in stabilizing the triple helix of collagen. Biochem. Biophys. Res. Commun. 1973, 52, 115-120.
-
(1973)
Biochem. Biophys. Res. Commun
, vol.52
, pp. 115-120
-
-
Berg, R.A.1
Prockop, D.J.2
-
23
-
-
0027996196
-
Crystal and molecular structure of a collagen-like peptide at 1.9 A resolution
-
Bella, J.; Eaton, M.; Brodsky, B.; Berman, H.M. Crystal and molecular structure of a collagen-like peptide at 1.9 A resolution. Science 1994, 266, 75-81.
-
(1994)
Science
, vol.266
, pp. 75-81
-
-
Bella, J.1
Eaton, M.2
Brodsky, B.3
Berman, H.M.4
-
24
-
-
33646127611
-
Award address. 2005 Emil Thomas Kaiser award
-
and references therein
-
Raines, R.T. Award address. 2005 Emil Thomas Kaiser award. Protein Sci. 2006, 15, 1219-1225, and references therein.
-
(2006)
Protein Sci
, vol.15
, pp. 1219-1225
-
-
Raines, R.T.1
-
25
-
-
0035977605
-
Conformational stability of collagen relies on a stereoelectronic effect
-
Bretscher, L.E.;Jenkins, C.L.; Taylor, K.M.; DeRider, M.L.; Raines, R.T. Conformational stability of collagen relies on a stereoelectronic effect. J. Am. Chem. Soc. 2001, 123, 777-778.
-
(2001)
J. Am. Chem. Soc
, vol.123
, pp. 777-778
-
-
Bretscher, L.E.1
Jenkins, C.L.2
Taylor, K.M.3
DeRider, M.L.4
Raines, R.T.5
-
26
-
-
0041708049
-
Stereoelectronic effects on collagen stability: the dichotomy of 4-fluoroproline diastereomers
-
Hodges, J.A.; Raines, R.T. Stereoelectronic effects on collagen stability: the dichotomy of 4-fluoroproline diastereomers. J. Am. Chem. Soc. 2003, 125, 9262-9263.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 9262-9263
-
-
Hodges, J.A.1
Raines, R.T.2
-
27
-
-
0043023397
-
10 does not
-
10 does not. J. Am. Chem. Soc. 2003, 125, 9922-9923.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 9922-9923
-
-
Doi, M.1
Nishi, Y.2
Uchiyama, S.3
Nishiuchi, Y.4
Nakazawa, T.5
Ohkubo, T.6
Kobayashi, Y.7
-
28
-
-
33745663038
-
Reciprocity of steric and stereoelectronic effects in the collagen triple helix
-
and references therein
-
Shoulders, M.D.; Hodges, J.A.; Raines, R.T. Reciprocity of steric and stereoelectronic effects in the collagen triple helix. J. Am. Chem. Soc. 2006, 128, 8112-8113, and references therein.
-
(2006)
J. Am. Chem. Soc
, vol.128
, pp. 8112-8113
-
-
Shoulders, M.D.1
Hodges, J.A.2
Raines, R.T.3
-
29
-
-
27844565701
-
Stereoelectronic and steric effects in the collagen triple helix: toward a code for strand association
-
and references therein
-
Hodges, J.A.; Raines, R.T. Stereoelectronic and steric effects in the collagen triple helix: toward a code for strand association. J. Am. Chem. Soc. 2005, 127, 15923-15932, and references therein.
-
(2005)
J. Am. Chem. Soc
, vol.127
, pp. 15923-15932
-
-
Hodges, J.A.1
Raines, R.T.2
-
30
-
-
33845789244
-
Fluoroproline flip-flop: regiochemical reversal of a stereoelectronic effect on peptide and protein structure
-
Kim, W.; Hardcastle, K.I.; Conticello, V.P. Fluoroproline flip-flop: regiochemical reversal of a stereoelectronic effect on peptide and protein structure. Angew Chem., Int. Ed. 2006, 45, 8141-8145.
-
(2006)
Angew Chem., Int. Ed
, vol.45
, pp. 8141-8145
-
-
Kim, W.1
Hardcastle, K.I.2
Conticello, V.P.3
-
31
-
-
0141682234
-
The synthesis and biological activity of C2-fluorinated pyrrolo[2, 1-c][1, 4]benzodiazepines
-
O'Neil, I.A.; Thompson, S.; Kalindjian, S.B.; Jenkins, T.C. The synthesis and biological activity of C2-fluorinated pyrrolo[2, 1-c][1, 4]benzodiazepines. Tetrahedron Lett. 2003, 44, 7809-7812.
-
(2003)
Tetrahedron Lett
, vol.44
, pp. 7809-7812
-
-
O'Neil, I.A.1
Thompson, S.2
Kalindjian, S.B.3
Jenkins, T.C.4
-
32
-
-
33746814848
-
An efficient solid-phase synthesis of biologically important DNA-interactive pyrrolo[2, 1-c][1, 4]benzodiazepine dimers (DSB-120) and their C2-fluorinated analogues
-
Kamal, A.; Shankaraiah, N.; Devaiah, V.; Reddy, K.L. An efficient solid-phase synthesis of biologically important DNA-interactive pyrrolo[2, 1-c][1, 4]benzodiazepine dimers (DSB-120) and their C2-fluorinated analogues. Tetrahedron Lett. 2006, 47, 6553-6556.
-
(2006)
Tetrahedron Lett
, vol.47
, pp. 6553-6556
-
-
Kamal, A.1
Shankaraiah, N.2
Devaiah, V.3
Reddy, K.L.4
-
33
-
-
5144228623
-
Synthesis of fluorinated analogues of SJG-136 and their DNA-binding potential
-
Kamal, A.; Reddy, P.S.M.M.; Reddy, D.R.; Laxman, E.; Murthy, Y.L.N. Synthesis of fluorinated analogues of SJG-136 and their DNA-binding potential. Bioorg. Med. Chem. Lett. 2004, 14, 5699-5702.
-
(2004)
Bioorg. Med. Chem. Lett
, vol.14
, pp. 5699-5702
-
-
Kamal, A.1
Reddy, P.S.M.M.2
Reddy, D.R.3
Laxman, E.4
Murthy, Y.L.N.5
-
34
-
-
0020535336
-
18F]Fluorine labeled aliphatic amino acids
-
18F]Fluorine labeled aliphatic amino acids. J. Label. Compd. Radiopharm. 1983, XX, 453-461.
-
(1983)
J. Label. Compd. Radiopharm
, vol.XX
, pp. 453-461
-
-
van der Ley, M.1
-
35
-
-
0032728491
-
18F]fluoro-L-proline, radiotracers for PET-investigation of disordered matrix protein synthesis
-
18F]fluoro-L-proline, radiotracers for PET-investigation of disordered matrix protein synthesis. J. Label. Compd. Radiopharm. 1999, 42, 1135-1144.
-
(1999)
J. Label. Compd. Radiopharm
, vol.42
, pp. 1135-1144
-
-
Hamacher, K.1
-
37
-
-
0033119039
-
18F]fluoroprolines: diastereomeric effect on metabolism and uptake in mice
-
18F]fluoroprolines: diastereomeric effect on metabolism and uptake in mice. Nucl. Med. Biol. 1999, 26, 259-265.
-
(1999)
Nucl. Med. Biol
, vol.26
, pp. 259-265
-
-
Wester, H.-J.1
Herz, M.2
Senekowitsch-Schmidtke, R.3
Schwaiger, M.4
Stücklin, G.5
Hamacher, K.6
-
38
-
-
0034998091
-
18F]fluoro-L-proline in urologic tumors
-
18F]fluoro-L-proline in urologic tumors. J. Nucl. Med. 2001, 42, 752-754.
-
(2001)
J. Nucl. Med
, vol.42
, pp. 752-754
-
-
Langen, K.-J.1
Borner, A.R.2
Muller-Mattheis, V.3
Hamacher, K.4
Herzog, H.5
Ackermann, R.6
Coenen, H.H.7
-
39
-
-
1642574305
-
18F]fluoro-L-proline
-
18F]fluoro-L-proline. Nucl. Med. Biol. 2004, 31, 67-75.
-
(2004)
Nucl. Med. Biol
, vol.31
, pp. 67-75
-
-
Langen, K.-J.1
Jarosch, M.2
Hamacher, K.3
Mühlensiepen, H.4
Weber, F.5
Floeth, F.6
Pauleit, D.7
Herzog, H.8
Coenen, H.H.9
-
40
-
-
17644381964
-
18 F] fluoro-proline at the blood-brain barrier
-
18 F] fluoro-proline at the blood-brain barrier. J. Cereb. Blood Flow Metab. 2005, 25, 607-616.
-
(2005)
J. Cereb. Blood Flow Metab
, vol.25
, pp. 607-616
-
-
Langen, K.-J.1
Hamacher, K.2
Bauer, D.3
Broer, S.4
Pauleit, D.5
Herzog, H.6
Floeth, F.7
Zilles, K.8
Coenen, H.H.9
-
41
-
-
0025651962
-
New stereospecific synthesis and X-ray diffraction structures of (-)-d-erythro-and (+ )-l-threo-4-fluoroglutamic acid
-
Hudlicky, M.; Merola, J.S. New stereospecific synthesis and X-ray diffraction structures of (-)-d-erythro-and (+ )-l-threo-4-fluoroglutamic acid. Tetrahedron Lett. 1990, 31, 7403-7406.
-
(1990)
Tetrahedron Lett
, vol.31
, pp. 7403-7406
-
-
Hudlicky, M.1
Merola, J.S.2
-
42
-
-
0027164569
-
The synthesis of dl-3, 3-difluoroglutamic acid from a 3-oxoprolinol derivative
-
Hart, B.P.; Coward, J.K. The synthesis of dl-3, 3-difluoroglutamic acid from a 3-oxoprolinol derivative. Tetrahedron Lett. 1993, 31, 4917-4920.
-
(1993)
Tetrahedron Lett
, vol.31
, pp. 4917-4920
-
-
Hart, B.P.1
Coward, J.K.2
-
43
-
-
0025082507
-
dl-3, 3-difluoroglutamate: an enhancer of folypolyglutamate elongation
-
McGuire, J.J.; Haile, W.H.; Bey, P.; Coward, J.K. dl-3, 3-difluoroglutamate: an enhancer of folypolyglutamate elongation. J. Biol. Chem. 1990, 265, 14073-14079.
-
(1990)
J. Biol. Chem
, vol.265
, pp. 14073-14079
-
-
McGuire, J.J.1
Haile, W.H.2
Bey, P.3
Coward, J.K.4
-
44
-
-
0035966190
-
Electrophilic fluorination of pyroglutamic acid derivatives: application of substrate-dependent reactivity and diastereoselectivity to the synthesis of optically active 4-fluoroglutamic acids
-
Konas, D.W.; Coward, J.K. Electrophilic fluorination of pyroglutamic acid derivatives: application of substrate-dependent reactivity and diastereoselectivity to the synthesis of optically active 4-fluoroglutamic acids. J. Org. Chem. 2001, 66, 8831-8842.
-
(2001)
J. Org. Chem
, vol.66
, pp. 8831-8842
-
-
Konas, D.W.1
Coward, J.K.2
-
45
-
-
0037414505
-
Synthesis of cis-4-trifluoromethyl-and cis-4-difluoromethyl-l-pyroglutamic acids
-
Qui, X.-L.; Qing, F.-L. Synthesis of cis-4-trifluoromethyl-and cis-4-difluoromethyl-l-pyroglutamic acids. J. Org. Chem. 2003, 68, 3614-3617.
-
(2003)
J. Org. Chem
, vol.68
, pp. 3614-3617
-
-
Qui, X.-L.1
Qing, F.-L.2
-
46
-
-
2542420119
-
Syntheses of 4-monofluoromethylenyl-and cis-4-monomethyl-l-pyroglutamic acids via a novel dehydrofluorination
-
Qiu, X.-L.; Meng, W.-D.; Qing, F.-L. Syntheses of 4-monofluoromethylenyl-and cis-4-monomethyl-l-pyroglutamic acids via a novel dehydrofluorination. Tetrahedron 2004, 60, 5201-5206.
-
(2004)
Tetrahedron
, vol.60
, pp. 5201-5206
-
-
Qiu, X.-L.1
Meng, W.-D.2
Qing, F.-L.3
-
47
-
-
0037067844
-
Synthesis and characterization of partially ß-fluorinated 5, 10, 15, 20-tetraphenylporphyrins and some derivatives
-
Leroy, J.; Porhiel, E.; Bondon, A. Synthesis and characterization of partially ß-fluorinated 5, 10, 15, 20-tetraphenylporphyrins and some derivatives. Tetrahedron 2002, 58, 6713-6722.
-
(2002)
Tetrahedron
, vol.58
, pp. 6713-6722
-
-
Leroy, J.1
Porhiel, E.2
Bondon, A.3
-
48
-
-
0028271218
-
Electrophilic fluorination of a highly functionalized pyrrole
-
Barnes, K.D.; Hu, Y.; Hunt, D.A. Electrophilic fluorination of a highly functionalized pyrrole. Synth. Commun. 1994, 24, 1749-1755.
-
(1994)
Synth. Commun
, vol.24
, pp. 1749-1755
-
-
Barnes, K.D.1
Hu, Y.2
Hunt, D.A.3
-
49
-
-
0035278460
-
Tetraarylporphyrin synthesis by electrochemical oxidation of porphyrinogens
-
Bondon, A.; Porhiel, E.; Pebay, C.; Thouin, L.; Leroy, J.; Moinet, C. Tetraarylporphyrin synthesis by electrochemical oxidation of porphyrinogens. Electrochim. Acta 2001, 46, 1899-1903.
-
(2001)
Electrochim. Acta
, vol.46
, pp. 1899-1903
-
-
Bondon, A.1
Porhiel, E.2
Pebay, C.3
Thouin, L.4
Leroy, J.5
Moinet, C.6
-
50
-
-
27844564327
-
Lewis acid catalyzed highly selective halogena-tion of aromatic compounds
-
Zhang, Y.; Shibatomi, K.; Yamamoto, H. Lewis acid catalyzed highly selective halogena-tion of aromatic compounds. Synlett 2005, 2837-2842.
-
(2005)
Synlett
, pp. 2837-2842
-
-
Zhang, Y.1
Shibatomi, K.2
Yamamoto, H.3
-
51
-
-
0028034079
-
First access to 3, 4-difluoro-1H-pyrrole
-
Leroy, J.; Wakselman, C. First access to 3, 4-difluoro-1H-pyrrole. Tetrahedron Lett. 1994, 35, 8605-8608.
-
(1994)
Tetrahedron Lett
, vol.35
, pp. 8605-8608
-
-
Leroy, J.1
Wakselman, C.2
-
52
-
-
0000543954
-
A straightforward synthesis of 3, 4-difluor-opyrrole
-
Woller, E.K.; Smirnov, V.V.; DiMagno, S.G. A straightforward synthesis of 3, 4-difluor-opyrrole. J. Org. Chem. 1998, 63, 5706-5707.
-
(1998)
J. Org. Chem
, vol.63
, pp. 5706-5707
-
-
Woller, E.K.1
Smirnov, V.V.2
DiMagno, S.G.3
-
53
-
-
84982055274
-
Ringverengung von Azidocyclobutenen zu Cyclopropancarbonitrilen
-
Buhr, G. Ringverengung von Azidocyclobutenen zu Cyclopropancarbonitrilen. Chem. Ber. 1973, 106, 3544-3558.
-
(1973)
Chem. Ber
, vol.106
, pp. 3544-3558
-
-
Buhr, G.1
-
54
-
-
0001332196
-
Fluoropyrroles and tetrafluorporphyrins
-
Onda, H.; Toi, H.; Aoyama, Y.; Ogoshi, H. Fluoropyrroles and tetrafluorporphyrins. Tetrahedron Lett. 1985, 26, 4221-4224.
-
(1985)
Tetrahedron Lett
, vol.26
, pp. 4221-4224
-
-
Onda, H.1
Toi, H.2
Aoyama, Y.3
Ogoshi, H.4
-
55
-
-
0028234158
-
A new approach to the synthesis of ß-fluoropyrrole derivatives
-
Qiu, Z.-M.; Burton, D.J. A new approach to the synthesis of ß-fluoropyrrole derivatives. Tetrahedron Lett. 1994, 35, 4319-4322.
-
(1994)
Tetrahedron Lett
, vol.35
, pp. 4319-4322
-
-
Qiu, Z.-M.1
Burton, D.J.2
-
56
-
-
0038204629
-
Convenient synthesis of polyfunctionalized ß-fluoropyrroles from rhodium(II)-catalyzed intramolecular N-H insertion reactions
-
Wang, Y.; Zhu, S. Convenient synthesis of polyfunctionalized ß-fluoropyrroles from rhodium(II)-catalyzed intramolecular N-H insertion reactions. Org. Lett. 2003, 5, 745-748.
-
(2003)
Org. Lett
, vol.5
, pp. 745-748
-
-
Wang, Y.1
Zhu, S.2
-
57
-
-
0023024932
-
Syntheses and analgesic/antiinflammatory activities of novel 2-[5-aroyl pyrrolo]alkanoic acids
-
Chang, M.N.; Biftu, T.; Boulton, D.A.; Finke, P.E.; Hammond, M.L.; Pessolano, A.A.; Zambias, R.A.; Bailey, P.; Goldenberg, M.; Rackham, A. Syntheses and analgesic/antiinflammatory activities of novel 2-[5-aroyl pyrrolo]alkanoic acids. Eur. J. Med. Chem. 1986, 21, 363-369.
-
(1986)
Eur. J. Med. Chem
, vol.21
, pp. 363-369
-
-
Chang, M.N.1
Biftu, T.2
Boulton, D.A.3
Finke, P.E.4
Hammond, M.L.5
Pessolano, A.A.6
Zambias, R.A.7
Bailey, P.8
Goldenberg, M.9
Rackham, A.10
-
58
-
-
0028339201
-
Fluorination of pyrrolic compounds with xenon difluoride
-
Wang, J.; Scott, A.I. Fluorination of pyrrolic compounds with xenon difluoride. Tetrahedron Lett. 1994, 35, 3679-3682.
-
(1994)
Tetrahedron Lett
, vol.35
, pp. 3679-3682
-
-
Wang, J.1
Scott, A.I.2
-
59
-
-
0028264165
-
Synthesis of the 2-fluoro-11-hydroxy analog of porphobilinogen, a new suicide inhibitor of the enzyme porphobilinogen deaminase
-
Wang, J.; Scott, A.I. Synthesis of the 2-fluoro-11-hydroxy analog of porphobilinogen, a new suicide inhibitor of the enzyme porphobilinogen deaminase. Tetrahedron 1994, 50, 6181-6192.
-
(1994)
Tetrahedron
, vol.50
, pp. 6181-6192
-
-
Wang, J.1
Scott, A.I.2
-
60
-
-
0029612207
-
4: a convenient general synthesis of fluoropyrroles
-
4: a convenient general synthesis of fluoropyrroles. J. Chem. Soc. 1995, 2399-2400.
-
(1995)
J. Chem. Soc
, pp. 2399-2400
-
-
Wang, J.1
Scott, A.I.2
-
61
-
-
0032551443
-
A facile tandem carbene-ylide route to 2-fluoropyrrole derivatives
-
Novikov, M.S.; Khlebnikov, A.F.; Sidorina, E.S.; Kostikov, R.R. A facile tandem carbene-ylide route to 2-fluoropyrrole derivatives. J. Fluorine Chem. 1998, 90, 117-119.
-
(1998)
J. Fluorine Chem
, vol.90
, pp. 117-119
-
-
Novikov, M.S.1
Khlebnikov, A.F.2
Sidorina, E.S.3
Kostikov, R.R.4
-
62
-
-
0034695708
-
1, 3-Dipolar cycloaddi-tion of azomethine ylides derived from imines and difluorocarbene to alkynes: a new active Pb-mediated approach to 2-fluoropyrrole derivatives
-
Novikov, M.S.; Khlebnikov, A.F.; Sidorina, E.S.; Kostikov, R.R. 1, 3-Dipolar cycloaddi-tion of azomethine ylides derived from imines and difluorocarbene to alkynes: a new active Pb-mediated approach to 2-fluoropyrrole derivatives. J. Chem. Soc., Perkin Trans. 1 2000, 231-237.
-
(2000)
J. Chem. Soc., Perkin Trans. 1
, pp. 231-237
-
-
Novikov, M.S.1
Khlebnikov, A.F.2
Sidorina, E.S.3
Kostikov, R.R.4
-
63
-
-
0141725355
-
A facile carbene route to 2-fluoro-2-pyrrolines via fluorinated azomethine ylides
-
Novikov, M.S.; Khlebnikov, A.F.; Shevchenko, M. A facile carbene route to 2-fluoro-2-pyrrolines via fluorinated azomethine ylides. J. Fluorine Chem. 2003, 123, 177-181.
-
(2003)
J. Fluorine Chem
, vol.123
, pp. 177-181
-
-
Novikov, M.S.1
Khlebnikov, A.F.2
Shevchenko, M.3
-
64
-
-
0000241475
-
Fluorocarbon derivatives of nitrogen. Part 18. Synthesis of fluorinated indolizines through reactions of pyridinium ethoxycarbonylmethylide or pyridinium phenacylide with perfluoropropene, perfluorobut-2-yne and 3, 3, 3-trifluoro-propyne
-
and references therein
-
Banks, R.E.; Khaffaff, S.N. Fluorocarbon derivatives of nitrogen. Part 18. Synthesis of fluorinated indolizines through reactions of pyridinium ethoxycarbonylmethylide or pyridinium phenacylide with perfluoropropene, perfluorobut-2-yne and 3, 3, 3-trifluoro-propyne. J. Fluorine Chem. 1991, 51, 407-418, and references therein.
-
(1991)
J. Fluorine Chem
, vol.51
, pp. 407-418
-
-
Banks, R.E.1
Khaffaff, S.N.2
-
65
-
-
0037238451
-
Synthesis of fluorinated indolizines and 4H-pyrrolo[1, 2-a]benzi-midazoles via 1, 3-dipolar cycloaddition of fluoroalkenes to N-ylides
-
Wu, K.; Chen, Q.-Y. Synthesis of fluorinated indolizines and 4H-pyrrolo[1, 2-a]benzi-midazoles via 1, 3-dipolar cycloaddition of fluoroalkenes to N-ylides. Synthesis 2003, 35-40.
-
(2003)
Synthesis
, pp. 35-40
-
-
Wu, K.1
Chen, Q.-Y.2
-
66
-
-
0032961098
-
A one-step approach to 1-(fluoroa!kyl)indolizine derivatives
-
Zhang, X.-c.; Huang, W.-y. A one-step approach to 1-(fluoroa!kyl)indolizine derivatives. Synthesis 1999, 51-54.
-
(1999)
Synthesis
, pp. 51-54
-
-
Zhang, X.-C.1
Huang, W.-Y.2
-
67
-
-
0002806895
-
Cycloaddition reactions of N-(cyanomethyl)pyridinium ylides with 2, 2-dihydropolyfluoroaIkanoates
-
Zhang, X.-c.; Huang, W.-y. Cycloaddition reactions of N-(cyanomethyl)pyridinium ylides with 2, 2-dihydropolyfluoroaIkanoates. J. Fluorine Chem. 1998, 92, 13-16.
-
(1998)
J. Fluorine Chem
, vol.92
, pp. 13-16
-
-
Zhang, X.-C.1
Huang, W.-Y.2
-
68
-
-
0032472099
-
A convenient synthesis of polyfluoroalkyl-substituted pyr-azolo[1, 5-a] pyridine, pyrrolo[1, 2-b]pyridazine and indolizine derivatives
-
Zhang, X.-c.; Huang, W.-y. A convenient synthesis of polyfluoroalkyl-substituted pyr-azolo[1, 5-a] pyridine, pyrrolo[1, 2-b]pyridazine and indolizine derivatives. J. Fluorine Chem. 1998, 87, 57-64.
-
(1998)
J. Fluorine Chem
, vol.87
, pp. 57-64
-
-
Zhang, X.-C.1
Huang, W.-Y.2
-
69
-
-
0032497682
-
Reaction of 1-alkylbenzimidazolium 3-ylides with ethyl 2, 2-dihydropolyfluoroalkanoates
-
Zhang, X.-c.; Huang, W.-y. Reaction of 1-alkylbenzimidazolium 3-ylides with ethyl 2, 2-dihydropolyfluoroalkanoates. Tetrahedron 1998, 54, 12465-12474.
-
(1998)
Tetrahedron
, vol.54
, pp. 12465-12474
-
-
Zhang, X.-C.1
Huang, W.-Y.2
-
70
-
-
0031008024
-
A new approach to pyrrolo[1, 2-a]quinoxaline derivatives
-
Zhang, X.-c.; Huang, W-y. A new approach to pyrrolo[1, 2-a]quinoxaline derivatives. Tetrahedron Lett. 1997, 38, 4827-4830.
-
(1997)
Tetrahedron Lett
, vol.38
, pp. 4827-4830
-
-
Zhang, X.-C.1
Huang, W.-Y.2
-
71
-
-
0000033912
-
Preparation of 1-trifluoroacetyl indolizines and their derivatives via the cycloaddition of pyridinium N-ylides with 4-4-ethoxy-1, 1, 1, -trifluorobut-3-en-one
-
Zhu, S.-z.; Qin, C.-y.; Wang, Y.-L.; Chu, Q.-l. Preparation of 1-trifluoroacetyl indolizines and their derivatives via the cycloaddition of pyridinium N-ylides with 4-4-ethoxy-1, 1, 1, -trifluorobut-3-en-one. J. Fluorine Chem. 1999, 99, 183-187.
-
(1999)
J. Fluorine Chem
, vol.99
, pp. 183-187
-
-
Zhu, S.-Z.1
Qin, C.-Y.2
Wang, Y.-L.3
Chu, Q.-L.4
-
72
-
-
2542421781
-
Synthesis of monofluorinated indolizines and their derivatives by the 1, 3-dipolar reaction of N-ylides with fluorinated vinyl tosylates
-
Fang, X.; Wu, Y.-M.; Deng, J.; Wang, S.-W. Synthesis of monofluorinated indolizines and their derivatives by the 1, 3-dipolar reaction of N-ylides with fluorinated vinyl tosylates. Tetrahedron 2004, 60, 5487-5493.
-
(2004)
Tetrahedron
, vol.60
, pp. 5487-5493
-
-
Fang, X.1
Wu, Y.-M.2
Deng, J.3
Wang, S.-W.4
-
73
-
-
0035862640
-
The first example of intramolecular cycloaddition of carbene-derived azomethine ylides in a domino reaction of difluorocarbene with Schiff bases
-
Novikov, M.S.; Khlebnikov, A.F.; Besedina, O.V.; Kostikov, R.R. The first example of intramolecular cycloaddition of carbene-derived azomethine ylides in a domino reaction of difluorocarbene with Schiff bases. Tetrahedron Lett. 2001, 42, 533-535.
-
(2001)
Tetrahedron Lett
, vol.42
, pp. 533-535
-
-
Novikov, M.S.1
Khlebnikov, A.F.2
Besedina, O.V.3
Kostikov, R.R.4
-
74
-
-
1542679244
-
Synthesis and biological activity of 5-fluorotubercidin
-
Wang, X.; Seth, P.P.; Ranken, R.; Swayze, E.E.; Migawa, M.T. Synthesis and biological activity of 5-fluorotubercidin. Nucleosides Nucleotides Nucleic Acids 2004, 23, 161-170.
-
(2004)
Nucleosides Nucleotides Nucleic Acids
, vol.23
, pp. 161-170
-
-
Wang, X.1
Seth, P.P.2
Ranken, R.3
Swayze, E.E.4
Migawa, M.T.5
-
75
-
-
0025778594
-
Total, asymmetric synthesis of (+ )-casta-nospermine, (+ )-6-deoxycastanospermine, and (+ )-6-deoxy-6-fluorocastanospermine
-
Reymond, J.-L.; Pinkerton, A.A.; Vogel, P. Total, asymmetric synthesis of (+ )-casta-nospermine, (+ )-6-deoxycastanospermine, and (+ )-6-deoxy-6-fluorocastanospermine. J. Org. Chem. 1991, 56, 2128-2135.
-
(1991)
J. Org. Chem
, vol.56
, pp. 2128-2135
-
-
Reymond, J.-L.1
Pinkerton, A.A.2
Vogel, P.3
-
76
-
-
0002087260
-
Monofluorodeuteroporphyrin IX dimethyl ester
-
Billig, M.J.; Baker, E.W. Monofluorodeuteroporphyrin IX dimethyl ester. Chem. Ind. 1969, 654-655.
-
(1969)
Chem. Ind
, pp. 654-655
-
-
Billig, M.J.1
Baker, E.W.2
-
77
-
-
0026602866
-
meso-Perfluorination of porphyrins with N-fluor-opyridinium triflate
-
Naruta, Y.; Tani, F.; Maruyama, K. meso-Perfluorination of porphyrins with N-fluor-opyridinium triflate. Tetrahedron Lett. 1992, 33, 1069-1072.
-
(1992)
Tetrahedron Lett
, vol.33
, pp. 1069-1072
-
-
Naruta, Y.1
Tani, F.2
Maruyama, K.3
-
78
-
-
33751158014
-
Facile synthesis of meso-tetrakis(per-fluoroalkyl)porphyrins: spectroscopic properties and X-ray crystal structure of highly electron-deficient 5, 10, 15, 20-tetrakis(heptafluoropropyl)porphyrin
-
DiMagno, S.G.; Williams, R.A.; Therien, M.J. Facile synthesis of meso-tetrakis(per-fluoroalkyl)porphyrins: spectroscopic properties and X-ray crystal structure of highly electron-deficient 5, 10, 15, 20-tetrakis(heptafluoropropyl)porphyrin. J. Org. Chem. 1994, 59, 6943-6948.
-
(1994)
J. Org. Chem
, vol.59
, pp. 6943-6948
-
-
DiMagno, S.G.1
Williams, R.A.2
Therien, M.J.3
-
79
-
-
7444247675
-
Electronic consequences of nonplanar core conformations in electron-deficient porphyrins: the structure and spectroscopic properties of [5, 10, 15, 20-tetrakis(heptafluoropropyl)-porphinato]cobalt(II)
-
DiMagno, S.G.; Wertsching, A.K.; Ross, C.R., II. Electronic consequences of nonplanar core conformations in electron-deficient porphyrins: the structure and spectroscopic properties of [5, 10, 15, 20-tetrakis(heptafluoropropyl)-porphinato]cobalt(II). J. Am. Chem. Soc. 1995, 117, 8279-8280.
-
(1995)
J. Am. Chem. Soc
, vol.117
, pp. 8279-8280
-
-
DiMagno, S.G.1
Wertsching, A.K.2
Ross II, C.R.3
-
80
-
-
0002785250
-
Synthesis of 1-fluoro-1-demethylmesopor-phyrin-IX
-
Suzuki, A.; Toi, H.; Aoyama, Y.; Ogoshi, H. Synthesis of 1-fluoro-1-demethylmesopor-phyrin-IX. Heterocycles 1992, 33, 87-90.
-
(1992)
Heterocycles
, vol.33
, pp. 87-90
-
-
Suzuki, A.1
Toi, H.2
Aoyama, Y.3
Ogoshi, H.4
-
81
-
-
1542298189
-
NMR investigation of the heme electronic structure in deoxymyoglobin possessing a fluorinated heme
-
Yamamoto, Y.; Nagao, S.; Hirai, Y.; Inose, T.; Terui, N.; Mita, H.; Suzuki, A. NMR investigation of the heme electronic structure in deoxymyoglobin possessing a fluorinated heme. J. Biol. Inorg. Chem. 2004, 9, 152-160.
-
(2004)
J. Biol. Inorg. Chem
, vol.9
, pp. 152-160
-
-
Yamamoto, Y.1
Nagao, S.2
Hirai, Y.3
Inose, T.4
Terui, N.5
Mita, H.6
Suzuki, A.7
-
82
-
-
0029905602
-
Synthesis of ringfluorinated porphyrins and reconstituted myoglobins with their iron complexes
-
Suzuki, A.; Tomizawa, T.; Hayashi, T.; Mizutani, T.; Ogoshi, H. Synthesis of ringfluorinated porphyrins and reconstituted myoglobins with their iron complexes. Bull. Chem. Soc. Jpn. 1996, 69, 2923-2933.
-
(1996)
Bull. Chem. Soc. Jpn
, vol.69
, pp. 2923-2933
-
-
Suzuki, A.1
Tomizawa, T.2
Hayashi, T.3
Mizutani, T.4
Ogoshi, H.5
-
83
-
-
0008270283
-
Electron deficient porphyrins. 1. Tetrakis(trifluoromethyl)porphyrin and its metal complexes
-
Homma, M.; Aoyagi, K.; Aoyama, Y.; Ogoshi, H. Electron deficient porphyrins. 1. Tetrakis(trifluoromethyl)porphyrin and its metal complexes. Tetrahedron Lett. 1983, 24, 4343-4346.
-
(1983)
Tetrahedron Lett
, vol.24
, pp. 4343-4346
-
-
Homma, M.1
Aoyagi, K.2
Aoyama, Y.3
Ogoshi, H.4
-
84
-
-
0002745631
-
Facile synthesis of perfluoroalkylporphyrins. Electron deficient porphyrins II
-
Aoyagi, K.; Toi, H.; Aoyama, Y.; Ogoshi, H. Facile synthesis of perfluoroalkylporphyrins. Electron deficient porphyrins II. Chem. Lett. 1988, 1891-1894.
-
(1988)
Chem. Lett
, pp. 1891-1894
-
-
Aoyagi, K.1
Toi, H.2
Aoyama, Y.3
Ogoshi, H.4
-
85
-
-
0000972547
-
2, 3, 7, 8, 12, 13, 17, 18-0ctafluoro-5, 10, 15, 20-tetraarylpor-phyrins and their zinc complexes: first spectroscopic, electrochemical, and structural characterization of a perfluorinated tetraarylmetalloporphyrin
-
Woller, E.K.; DiMagno, S.G. 2, 3, 7, 8, 12, 13, 17, 18-0ctafluoro-5, 10, 15, 20-tetraarylpor-phyrins and their zinc complexes: first spectroscopic, electrochemical, and structural characterization of a perfluorinated tetraarylmetalloporphyrin. J. Org. Chem. 1997, 62, 1588-1593.
-
(1997)
J. Org. Chem
, vol.62
, pp. 1588-1593
-
-
Woller, E.K.1
DiMagno, S.G.2
-
86
-
-
0030733823
-
2, 3, 7, 8, 12, 13, 17, 18-Octafluoro-5, 10, 15, 20-tetraphenylporphyrin: first synthesis and X-ray crystal structure of the ZnII complex
-
Leroy, J.; Bondon, A.; Toupet, L.; Rolando, C. 2, 3, 7, 8, 12, 13, 17, 18-Octafluoro-5, 10, 15, 20-tetraphenylporphyrin: first synthesis and X-ray crystal structure of the ZnII complex. Chem. Eur. J. 1997, 3, 1890-1893.
-
(1997)
Chem. Eur. J
, vol.3
, pp. 1890-1893
-
-
Leroy, J.1
Bondon, A.2
Toupet, L.3
Rolando, C.4
-
87
-
-
0141591659
-
Slow electron transfer rates for fluorinated cobalt porphyrins: electronic and conformational factors modulating metalloporphyrin ET
-
Sun, H.; Smirnov, V.V.; DiMagno, S.G. Slow electron transfer rates for fluorinated cobalt porphyrins: electronic and conformational factors modulating metalloporphyrin ET. Inorg. Chem. 2003, 42, 6032-6040.
-
(2003)
Inorg. Chem
, vol.42
, pp. 6032-6040
-
-
Sun, H.1
Smirnov, V.V.2
DiMagno, S.G.3
-
88
-
-
0033828427
-
Umpolung of a metal-carbon bond: a potential route to porphyrin-based methane functionalization catalysts
-
Nelson, A.P.; DiMagno, S.G. Umpolung of a metal-carbon bond: a potential route to porphyrin-based methane functionalization catalysts. J. Am. Chem. Soc. 2000, 122, 8569-8570.
-
(2000)
J. Am. Chem. Soc
, vol.122
, pp. 8569-8570
-
-
Nelson, A.P.1
DiMagno, S.G.2
-
89
-
-
27944472608
-
VI/V) and C-H bond-dissociation energy on rate constants
-
and references therein
-
VI/V) and C-H bond-dissociation energy on rate constants. Chem. Eur. J. 2005, 11, 7040-7053, and references therein.
-
(2005)
Chem. Eur. J
, vol.11
, pp. 7040-7053
-
-
Che, C.-M.1
Zhang, J.-L.2
Zhang, R.3
Huang, J.-S.4
Lai, T.-S.5
Tsui, W.-M.6
Zhou, X.-G.7
Zhou, Z.-Y.8
Zhu, N.9
Chang, C.K.10
-
90
-
-
0037064521
-
On the role of ß-fluorine substitution on the extent of core deformation of porphyrin dications
-
Porhiel, E.; Toupet, L.; Leroy, J.; Bondon, A. On the role of ß-fluorine substitution on the extent of core deformation of porphyrin dications. Tetrahedron Lett. 2002, 43, 8293-8296.
-
(2002)
Tetrahedron Lett
, vol.43
, pp. 8293-8296
-
-
Porhiel, E.1
Toupet, L.2
Leroy, J.3
Bondon, A.4
-
91
-
-
0034923738
-
Synthesis of fluorinated analogs of porphyrins potentially useful for the diagnosis and therapy of cancer
-
Kumadaki, I.; Ando, A.; Omote, M. Synthesis of fluorinated analogs of porphyrins potentially useful for the diagnosis and therapy of cancer. J. Fluorine Chem. 2001, 109, 67-81.
-
(2001)
J. Fluorine Chem
, vol.109
, pp. 67-81
-
-
Kumadaki, I.1
Ando, A.2
Omote, M.3
-
92
-
-
0034715470
-
Fluorinated calix[4]pyrrole and dipyrrolylquinoxaline: neutral anion receptors with augmented affinities and enhanced selectivities
-
and references therein
-
Anzenbacher, P., Jr.; Try, A.C.; Miyaji, H.; Jursíková, K.; Lynch, V.M.; Marquez, M.; Sessler, J.L. Fluorinated calix[4]pyrrole and dipyrrolylquinoxaline: neutral anion receptors with augmented affinities and enhanced selectivities. J. Am. Chem. Soc. 2000, 122, 10268-10272, and references therein.
-
(2000)
J. Am. Chem. Soc
, vol.122
, pp. 10268-10272
-
-
Anzenbacher Jr., P.1
Try, A.C.2
Miyaji, H.3
Jursíková, K.4
Lynch, V.M.5
Marquez, M.6
Sessler, J.L.7
-
93
-
-
22244481542
-
Anion binding studies of fluorinated expanded calixpyrroles
-
and references therein
-
Sessler, J.L.; Cho, W.-S.; Gross, D.E.; Shriver, J.A.; Lynch, V.M.; Marquez, M. Anion binding studies of fluorinated expanded calixpyrroles. J. Org. Chem. 2005, 70, 5982-5986, and references therein.
-
(2005)
J. Org. Chem
, vol.70
, pp. 5982-5986
-
-
Sessler, J.L.1
Cho, W.-S.2
Gross, D.E.3
Shriver, J.A.4
Lynch, V.M.5
Marquez, M.6
-
94
-
-
0033577883
-
The first direct synthesis of corroles from pyrrole
-
Gross, Z.; Galili, N.; Saltsman, I. The first direct synthesis of corroles from pyrrole. Angew Chem., Int. Ed. 1999, 38, 1427-1429.
-
(1999)
Angew Chem., Int. Ed
, vol.38
, pp. 1427-1429
-
-
Gross, Z.1
Galili, N.2
Saltsman, I.3
-
95
-
-
0000534548
-
Solvent-free condensation of pyrrole and pentafluorobenzaldehyde: a novel synthetic pathway to corrole and oligopyrromethenes
-
Gross, Z.; Galili, N.; Simkhovich, L.; Saltsman, I.; Botoshansky, M.; Blaser, D.; Boese, R.; Goldberg, I. Solvent-free condensation of pyrrole and pentafluorobenzaldehyde: a novel synthetic pathway to corrole and oligopyrromethenes. Org. Lett. 1999, 1, 599-602.
-
(1999)
Org. Lett
, vol.1
, pp. 599-602
-
-
Gross, Z.1
Galili, N.2
Simkhovich, L.3
Saltsman, I.4
Botoshansky, M.5
Blaser, D.6
Boese, R.7
Goldberg, I.8
-
96
-
-
0347064292
-
ß-Octafluorocorroles
-
Steene, E.; Dey, A.; Ghosh, A. ß-Octafluorocorroles. J. Am. Chem. Soc. 2003, 125, 16300-16309.
-
(2003)
J. Am. Chem. Soc
, vol.125
, pp. 16300-16309
-
-
Steene, E.1
Dey, A.2
Ghosh, A.3
-
97
-
-
0141629868
-
First synthesis of perfluorinated corrole and its Mn=O complex
-
Liu, H.-Y.; Lai, T.-S.; Yeung, L.-L.; Chang, C.K. First synthesis of perfluorinated corrole and its Mn=O complex. Org. Lett. 2003, 5, 617-620.
-
(2003)
Org. Lett
, vol.5
, pp. 617-620
-
-
Liu, H.-Y.1
Lai, T.-S.2
Yeung, L.-L.3
Chang, C.K.4
-
98
-
-
0015228994
-
Photochemical decomposition of diazonium fluoroborates. Application to the synthesis of ring-fluorinated imidazoles
-
Kirk, K.L.; Cohen, L.A. Photochemical decomposition of diazonium fluoroborates. Application to the synthesis of ring-fluorinated imidazoles. J. Am. Chem. Soc. 1971, 93, 3060-3061.
-
(1971)
J. Am. Chem. Soc
, vol.93
, pp. 3060-3061
-
-
Kirk, K.L.1
Cohen, L.A.2
-
99
-
-
0015920812
-
Photochemistry of diazonium salts I. Synthesis of 4-fluoroimi-dazoles, 4-fluorohistamine, and 4-fluorohistidine
-
Kirk, K.L.; Cohen, L.A. Photochemistry of diazonium salts I. Synthesis of 4-fluoroimi-dazoles, 4-fluorohistamine, and 4-fluorohistidine. J. Am. Chem. Soc. 1973, 95, 4619-4624.
-
(1973)
J. Am. Chem. Soc
, vol.95
, pp. 4619-4624
-
-
Kirk, K.L.1
Cohen, L.A.2
-
100
-
-
0015921945
-
Photochemistry of diazonium salts. II. Synthesis of 2-fluorohistidine and 2-fluorohistamine, and the halogen mobility of 2-fluoroimidazoles
-
Kirk, K.L.; Nagai, W.; Cohen, L.A. Photochemistry of diazonium salts. II. Synthesis of 2-fluorohistidine and 2-fluorohistamine, and the halogen mobility of 2-fluoroimidazoles. J. Am. Chem. Soc. 1973, 95, 8389-8392.
-
(1973)
J. Am. Chem. Soc
, vol.95
, pp. 8389-8392
-
-
Kirk, K.L.1
Nagai, W.2
Cohen, L.A.3
-
101
-
-
0037874420
-
Biochemistry and pharmacology of ring-fluorinated imidazoles
-
In, No 28; Filler, R., Ed.; American Chemical Society, Washington D.C.
-
Kirk, K.L.; Cohen, L.A. Biochemistry and pharmacology of ring-fluorinated imidazoles. In Biochemistry of the Carbon-Fluorine Bond, ACS Symposium Series No 28; Filler, R., Ed.; American Chemical Society, Washington D.C., 1976; 23-36.
-
(1976)
Biochemistry of the Carbon-Fluorine Bond, ACS Symposium Series
, pp. 23-36
-
-
Kirk, K.L.1
Cohen, L.A.2
-
102
-
-
0015888244
-
Synthesis of 2-amino-l-histidine and 2-aminohis-tamine
-
Nagai, W.; Kirk, K.L.; Cohen, L.A. Synthesis of 2-amino-l-histidine and 2-aminohis-tamine. J. Org. Chem. 1973, 38, 1971-1974.
-
(1973)
J. Org. Chem
, vol.38
, pp. 1971-1974
-
-
Nagai, W.1
Kirk, K.L.2
Cohen, L.A.3
-
103
-
-
0015896320
-
Photochemistry of diazonium salts. III. A new and facile synthesis of 4-fluoroimidazoles
-
Kirk, K.L.; Cohen, L.A. Photochemistry of diazonium salts. III. A new and facile synthesis of 4-fluoroimidazoles. J. Org. Chem. 1973, 38, 3647-3648.
-
(1973)
J. Org. Chem
, vol.38
, pp. 3647-3648
-
-
Kirk, K.L.1
Cohen, L.A.2
-
104
-
-
0035180478
-
Synthesis of 4, 5-difluoroimidazole
-
Dolensky, B.; Takeuchi, Y.; Cohen, L.A.; Kirk, K.L. Synthesis of 4, 5-difluoroimidazole. J. Fluorine Chem. 2001, 107, 147-148.
-
(2001)
J. Fluorine Chem
, vol.107
, pp. 147-148
-
-
Dolensky, B.1
Takeuchi, Y.2
Cohen, L.A.3
Kirk, K.L.4
-
105
-
-
0000672881
-
Photochemistry of diazonium salts. 5. Syntheses of ethyl 2, 4-difluoroimidazole-5-carboxylate and related compounds
-
Takahashi, K.; Kirk, K.L.; Cohen, L.A. Photochemistry of diazonium salts. 5. Syntheses of ethyl 2, 4-difluoroimidazole-5-carboxylate and related compounds. J. Org. Chem. 1984, 49, 1951-1954.
-
(1984)
J. Org. Chem
, vol.49
, pp. 1951-1954
-
-
Takahashi, K.1
Kirk, K.L.2
Cohen, L.A.3
-
106
-
-
0000550020
-
Phototransposition chemistry of 1-methylpyrazole. Deuterium, methyl, and fluorine substitution
-
Pavlik, J.W.; Kurzweil, E.M. Phototransposition chemistry of 1-methylpyrazole. Deuterium, methyl, and fluorine substitution. J. Org. Chem. 1991, 56, 6313-6320.
-
(1991)
J. Org. Chem
, vol.56
, pp. 6313-6320
-
-
Pavlik, J.W.1
Kurzweil, E.M.2
-
107
-
-
0033525626
-
Synthesis and characterization of derivatives and dimers of 4, 5-dicyanoimidazole
-
Coad, E.C.; Liu, H.; Rasmussen, P.G. Synthesis and characterization of derivatives and dimers of 4, 5-dicyanoimidazole. Tetrahedron 1999, 55, 2811-2826.
-
(1999)
Tetrahedron
, vol.55
, pp. 2811-2826
-
-
Coad, E.C.1
Liu, H.2
Rasmussen, P.G.3
-
108
-
-
33846484821
-
Fluoride relay: a new concept for the rapid preparation of anhydrous nucleophilic fluoride salts from KF
-
Sun, H.; DiMagno, S.G. Fluoride relay: a new concept for the rapid preparation of anhydrous nucleophilic fluoride salts from KF. Chem. Commun. 2007, 528-529.
-
(2007)
Chem. Commun
, pp. 528-529
-
-
Sun, H.1
DiMagno, S.G.2
-
109
-
-
0023846160
-
Übereine neue Methode zurpositionsselektivenEinführung von Trifluormethyl-Gruppen in Heteroaromaten, Teil 1. Synthese von trifluormethyl-substituierten 1, 3-Azolen (oxazole, thiazole, imidazole)
-
Burger, K.; Geith, G.; Hubel, D. Übereine neue Methode zurpositionsselektivenEinführung von Trifluormethyl-Gruppen in Heteroaromaten, Teil 1. Synthese von trifluormethyl-substituierten 1, 3-Azolen (oxazole, thiazole, imidazole). Synthesis 1988, 189-194.
-
(1988)
Synthesis
, pp. 189-194
-
-
Burger, K.1
Geith, G.2
Hubel, D.3
-
110
-
-
0023838213
-
Über eine neue Methode zur positionsselektiven Einfüuhrung von Trifluormethyl-Gruppen in Heteroaromaten, Teil 2. Nucleophile Substitution an 5-fluor-4-trifluormethyl-substituierten 1, 3-Azolen
-
Burger, K.; Hübel, D.; Geith, K. Über eine neue Methode zur positionsselektiven Einfüuhrung von Trifluormethyl-Gruppen in Heteroaromaten, Teil 2. Nucleophile Substitution an 5-fluor-4-trifluormethyl-substituierten 1, 3-Azolen. Synthesis 1988, 194-198.
-
(1988)
Synthesis
, pp. 194-198
-
-
Burger, K.1
Hübel, D.2
Geith, K.3
-
111
-
-
4243884414
-
Les fluoroazoles: syntheses, proprietes et applications
-
and thesis cited therein
-
Bouchet, P.; Coquelet, C.; Elguero, J. Les fluoroazoles: syntheses, proprietes et applications. Bull. Soc. Chim. Fr. 1977, 171-180, and thesis cited therein.
-
(1977)
Bull. Soc. Chim. Fr
, pp. 171-180
-
-
Bouchet, P.1
Coquelet, C.2
Elguero, J.3
-
112
-
-
84890982469
-
Electrophilic fluorination of tin and mercury derivatives as aroute to fluoroaromatics
-
Bryce, M.R.; Chambers, R.D.; Mullins, S.T.; Parkin, A. Electrophilic fluorination of tin and mercury derivatives as aroute to fluoroaromatics. Bull. Chim. Soc. Fr. 1986, 930-932.
-
(1986)
Bull. Chim. Soc. Fr
, pp. 930-932
-
-
Bryce, M.R.1
Chambers, R.D.2
Mullins, S.T.3
Parkin, A.4
-
113
-
-
0016828320
-
4-Trifluoromethylimidazoles and 5-(4-pyridyl)-1, 2, 4-triazoles, new classes of xanthine oxidase inhibitors
-
Baldwin, J.J.; Kasinger, P.A.; Novello, F.C.; Sprague, J.M. 4-Trifluoromethylimidazoles and 5-(4-pyridyl)-1, 2, 4-triazoles, new classes of xanthine oxidase inhibitors. J. Med. Chem. 1975, 18, 895-900.
-
(1975)
J. Med. Chem
, vol.18
, pp. 895-900
-
-
Baldwin, J.J.1
Kasinger, P.A.2
Novello, F.C.3
Sprague, J.M.4
-
114
-
-
0011919532
-
A facile synthesis of 2-(trifluoromethyl)histamine and 2-(trifluoromethyl)histidine
-
Kimoto, H.; Kirk, K.L.; Cohen, L.A. A facile synthesis of 2-(trifluoromethyl)histamine and 2-(trifluoromethyl)histidine. J. Org. Chem. 1978, 43, 3403-3405.
-
(1978)
J. Org. Chem
, vol.43
, pp. 3403-3405
-
-
Kimoto, H.1
Kirk, K.L.2
Cohen, L.A.3
-
115
-
-
0021365919
-
Photochemical trifluoromethylation of some biologically significant imidazoles
-
Kimoto, H.; Fujii, S.; Cohen, L.A. Photochemical trifluoromethylation of some biologically significant imidazoles. J. Org. Chem. 1984, 49, 1060-1064.
-
(1984)
J. Org. Chem
, vol.49
, pp. 1060-1064
-
-
Kimoto, H.1
Fujii, S.2
Cohen, L.A.3
-
116
-
-
0000627759
-
Photochemical perfluorination of imidazoles
-
Kimoto, H.; Fujii, S.; Cohen, L.A. Photochemical perfluorination of imidazoles. J. Org. Chem. 1982, 47, 2867-2872.
-
(1982)
J. Org. Chem
, vol.47
, pp. 2867-2872
-
-
Kimoto, H.1
Fujii, S.2
Cohen, L.A.3
-
117
-
-
0029799813
-
Elemental fluorine to 8-fluoropurines in one step
-
Barrio, J.R.; Namavari, M.; Phelps, M.E.; Satyamurthy, N. Elemental fluorine to 8-fluoropurines in one step. J. Am. Chem. Soc. 1996, 118, 10408-10411.
-
(1996)
J. Am. Chem. Soc
, vol.118
, pp. 10408-10411
-
-
Barrio, J.R.1
Namavari, M.2
Phelps, M.E.3
Satyamurthy, N.4
-
118
-
-
0032191562
-
The elusive 8-fluoroadenosine
-
Barrio, J.R.; Namavari, M.; Keen, R.E.; Satyamurthy, N. The elusive 8-fluoroadenosine. Tetrahedron Lett. 1998, 39, 7231-7234.
-
(1998)
Tetrahedron Lett
, vol.39
, pp. 7231-7234
-
-
Barrio, J.R.1
Namavari, M.2
Keen, R.E.3
Satyamurthy, N.4
-
119
-
-
33748290068
-
Kinetics and mechanism of the defluorination of 8-fluoropurine nucleosides in basic and acidic media
-
Liu, J.; Barrio, J.R.; Satyamurthy, N. Kinetics and mechanism of the defluorination of 8-fluoropurine nucleosides in basic and acidic media. J. Fluorine Chem. 2006, 127, 1175-1187.
-
(2006)
J. Fluorine Chem
, vol.127
, pp. 1175-1187
-
-
Liu, J.1
Barrio, J.R.2
Satyamurthy, N.3
-
120
-
-
0033625192
-
18F]fluoroguanine derivatives: in vivo probes for imaging gene expression with positron emission tomography
-
18F]fluoroguanine derivatives: in vivo probes for imaging gene expression with positron emission tomography. Nucl. Med. Biol. 2000, 27, 157-162.
-
(2000)
Nucl. Med. Biol
, vol.27
, pp. 157-162
-
-
Namavari, M.1
Barrio, J.R.2
Toyokuni, T.3
Gambhir, S.S.4
Cherry, S.R.5
Herschman, H.R.6
Phelps, M.E.7
Satyamurthy, N.8
-
121
-
-
33947643729
-
The elusive 8-fluoroadenosine: a simple non-enzymatic synthesis and characterization
-
Butora, G.; Schmitt, C.; Levorse, D.A.; Streckfuss, E.; Doss, G.A.; MacCoss, M. The elusive 8-fluoroadenosine: a simple non-enzymatic synthesis and characterization. Tetrahedron 2007, 63, 3782-3789.
-
(2007)
Tetrahedron
, vol.63
, pp. 3782-3789
-
-
Butora, G.1
Schmitt, C.2
Levorse, D.A.3
Streckfuss, E.4
Doss, G.A.5
MacCoss, M.6
-
122
-
-
0033578610
-
Properly tuned first fluoride-catalyzed TGME-mediated amination process for chloroimidazoles: inexpensive technology for antihis-taminic norastemizole
-
Senanayake, C.H.; Hong, Y.; Xiang, T.; Wilkinson, H.S.; Bakale, R.P.; Jurgens, A. R.; Pippert, M.F.; Butler, H.T.; Wald, S.A. Properly tuned first fluoride-catalyzed TGME-mediated amination process for chloroimidazoles: inexpensive technology for antihis-taminic norastemizole. Tetrahedron Lett. 1999, 40, 6875-6879.
-
(1999)
Tetrahedron Lett
, vol.40
, pp. 6875-6879
-
-
Senanayake, C.H.1
Hong, Y.2
Xiang, T.3
Wilkinson, H.S.4
Bakale, R.P.5
Jurgens, A.R.6
Pippert, M.F.7
Butler, H.T.8
Wald, S.A.9
-
123
-
-
33746255373
-
Room-temperature nucleophilic aromatic fluorination: experimental and theoretical studies
-
Sun, H.; DiMagno, S.G. Room-temperature nucleophilic aromatic fluorination: experimental and theoretical studies. Angew Chem., Int. Ed. 2006, 45, 2720-2725.
-
(2006)
Angew Chem., Int. Ed
, vol.45
, pp. 2720-2725
-
-
Sun, H.1
DiMagno, S.G.2
-
125
-
-
0018634904
-
Imidazole cyclotrimers (trimidazoles), a novel heteroannular series
-
Takeuchi, Y.; Kirk, K.L.; Cohen, L.A. Imidazole cyclotrimers (trimidazoles), a novel heteroannular series. J. Org. Chem. 1979, 44, 4243-4246.
-
(1979)
J. Org. Chem
, vol.44
, pp. 4243-4246
-
-
Takeuchi, Y.1
Kirk, K.L.2
Cohen, L.A.3
-
126
-
-
0027199445
-
a of the C-7 aminoimidazole on antibacterial spectrum and ß-lactamase stability
-
a of the C-7 aminoimidazole on antibacterial spectrum and ß-lactamase stability. J. Antibiot. 1993, 46, 992-1012.
-
(1993)
J. Antibiot
, vol.46
, pp. 992-1012
-
-
Jung, F.1
Boucherot, D.2
Delvare, C.3
Olivier, A.4
-
127
-
-
0040301765
-
2-Fluoro-l-histidine: a histidine analog which inhibits enzyme induction
-
In, Filler, R., Ed.; American Chemical Society, Washington D.C.
-
Klein, D.C.; Kirk, K.L. 2-Fluoro-l-histidine: a histidine analog which inhibits enzyme induction. In Biochemistry of the Carbon-Fluorine Bond, ACS Symposium Series; Filler, R., Ed.; American Chemical Society, Washington D.C., 1976; 37-56.
-
(1976)
Biochemistry of the Carbon-Fluorine Bond, ACS Symposium Series
, pp. 37-56
-
-
Klein, D.C.1
Kirk, K.L.2
-
128
-
-
0017353193
-
Effect of 2-fluorohistidine upon leukocytopoi-esis in mice
-
Creveling, C.R.; Kirk, K.L.; Highman, B. Effect of 2-fluorohistidine upon leukocytopoi-esis in mice. Res. Commun. Chem. Pathol. Pharmacol. 1977, 16, 507-522.
-
(1977)
Res. Commun. Chem. Pathol. Pharmacol
, vol.16
, pp. 507-522
-
-
Creveling, C.R.1
Kirk, K.L.2
Highman, B.3
-
129
-
-
0026775710
-
Incorporation of 2-fluorohistidine in murine protein in vivo
-
Creveling, C.R.; Padgett, W.L.; McNeal, E.T.; Cohen, L.A.; Kirk, K.L. Incorporation of 2-fluorohistidine in murine protein in vivo. Life Sci. 1992, 51, 1197-1204.
-
(1992)
Life Sci
, vol.51
, pp. 1197-1204
-
-
Creveling, C.R.1
Padgett, W.L.2
McNeal, E.T.3
Cohen, L.A.4
Kirk, K.L.5
-
130
-
-
37349043646
-
Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation, and translocation
-
Wimalasena, D.S.; Cramer, J.C.; Janowiak, B.E.; Juris, S.J.; Melnyk, R.A.; Anderson, D.E.; Kirk, K.L.; Collier, J.R.; Bann, J.G. Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation, and translocation. Biochemistry 2007, 46, 14928-14936.
-
(2007)
Biochemistry
, vol.46
, pp. 14928-14936
-
-
Wimalasena, D.S.1
Cramer, J.C.2
Janowiak, B.E.3
Juris, S.J.4
Melnyk, R.A.5
Anderson, D.E.6
Kirk, K.L.7
Collier, J.R.8
Bann, J.G.9
-
131
-
-
13444266910
-
Synthesis and biological evaluation of the 1, 5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazole-1-yl]benzene-sulfonamide (SC-58635, celecoxib)
-
Penning, T.D.; Talley, J.J.; Bertenshaw, S.R.; Carter, J.S.; Collins, P.W.; Docter, S.; Graneto, M.J.; Lee, L.F.; Malecha, J.W.; Miyashiro, J.M.; Rogers, R.S.; Rogier, D.J.; Yu, S.S.; Anderson, G.D.; Burton, E.G.; Cogburn, J.N.; Gregory, S.A.; Koboldt, C.M.; Perkins, W.E.; Siebert, K.; Veenhuizen, A.W.; Zhang, Y.Y.; Isakson, P.C. Synthesis and biological evaluation of the 1, 5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazole-1-yl]benzene-sulfonamide (SC-58635, celecoxib). J. Med. Chem. 1997, 40, 1347-1365.
-
(1997)
J. Med. Chem
, vol.40
, pp. 1347-1365
-
-
Penning, T.D.1
Talley, J.J.2
Bertenshaw, S.R.3
Carter, J.S.4
Collins, P.W.5
Docter, S.6
Graneto, M.J.7
Lee, L.F.8
Malecha, J.W.9
Miyashiro, J.M.10
Rogers, R.S.11
Rogier, D.J.12
Yu, S.S.13
Anderson, G.D.14
Burton, E.G.15
Cogburn, J.N.16
Gregory, S.A.17
Koboldt, C.M.18
Perkins, W.E.19
Siebert, K.20
Veenhuizen, A.W.21
Zhang, Y.Y.22
Isakson, P.C.23
more..
-
132
-
-
0018250297
-
19F NMR spectra of 3-, 4-, and 5-fluoro-1-methylpyrazole
-
19F NMR spectra of 3-, 4-, and 5-fluoro-1-methylpyrazole. J. Heterocycl. Chem. 1978, 15, 1447-1449.
-
(1978)
J. Heterocycl. Chem
, vol.15
, pp. 1447-1449
-
-
Fabra, F.1
Vilarrasa, J.2
Coll, J.3
-
133
-
-
0010858015
-
19F Couplilng constants in the azole series. Synthesis of 3, 4-, 4, 5-, and 3, 5-difluoropyrazoles
-
19F Couplilng constants in the azole series. Synthesis of 3, 4-, 4, 5-, and 3, 5-difluoropyrazoles. Tetrahedron Lett. 1979, 34, 3179-3180.
-
(1979)
Tetrahedron Lett
, vol.34
, pp. 3179-3180
-
-
Fabra, F.1
Fos, E.2
-
134
-
-
0000646668
-
Selective fluorination of ethyl 1-methylpyrazole-4-carbox-ylates with poly(hydrogen fluoride)-amine complex under electrolytic anodic oxidation
-
Makino, K.; Yoshioka, H. Selective fluorination of ethyl 1-methylpyrazole-4-carbox-ylates with poly(hydrogen fluoride)-amine complex under electrolytic anodic oxidation. J. Fluorine Chem. 1988, 39, 435-440.
-
(1988)
J. Fluorine Chem
, vol.39
, pp. 435-440
-
-
Makino, K.1
Yoshioka, H.2
-
136
-
-
0024849506
-
Fluoromalonaldehyde bis(dialkyl acetals): synthesis by carbene condensation and transformation to dialkyl fluoromalonates and fluorinated heterocyclic compounds
-
Molines, H.; Wakselman, C. Fluoromalonaldehyde bis(dialkyl acetals): synthesis by carbene condensation and transformation to dialkyl fluoromalonates and fluorinated heterocyclic compounds. J. Org. Chem. 1989, 54, 5618-5620.
-
(1989)
J. Org. Chem
, vol.54
, pp. 5618-5620
-
-
Molines, H.1
Wakselman, C.2
-
137
-
-
0035136831
-
Efficient synthesis of 4-fluoro-5-(perfluoroalkyl)pyrazoles from organofluorosilicon building blocks
-
Bouillon, J.-P.; Didier, B.; Dondy, B.; Doussot, P.; Plantier-Royon, R.; Portella, C. Efficient synthesis of 4-fluoro-5-(perfluoroalkyl)pyrazoles from organofluorosilicon building blocks. Eur. J. Org. Chem. 2001, 187-192.
-
(2001)
Eur. J. Org. Chem
, pp. 187-192
-
-
Bouillon, J.-P.1
Didier, B.2
Dondy, B.3
Doussot, P.4
Plantier-Royon, R.5
Portella, C.6
-
138
-
-
0029948459
-
Regiocon-trolled syntheses of 3-or 5-fluorinated pyrazoles from 2, 2-difluorovinyl ketones
-
Ichikawa, J.; Kobayashi, M.; Noda, Y.; Yokata, N.; Amano, K.; Minami, T. Regiocon-trolled syntheses of 3-or 5-fluorinated pyrazoles from 2, 2-difluorovinyl ketones. J. Org. Chem. 1996, 61, 2763-2769.
-
(1996)
J. Org. Chem
, vol.61
, pp. 2763-2769
-
-
Ichikawa, J.1
Kobayashi, M.2
Noda, Y.3
Yokata, N.4
Amano, K.5
Minami, T.6
-
139
-
-
0028959333
-
Reactions of ß-fluorovinamidinium salt with bifunctional hetero nucleophiles. A new synthetic route to fluorinated heterocycles
-
Shi, X.; Ishihara, T.; Yamanaka, H.; Gupton, J.T. Reactions of ß-fluorovinamidinium salt with bifunctional hetero nucleophiles. A new synthetic route to fluorinated heterocycles. Tetrahedron Lett. 1995, 36, 1527-1530.
-
(1995)
Tetrahedron Lett
, vol.36
, pp. 1527-1530
-
-
Shi, X.1
Ishihara, T.2
Yamanaka, H.3
Gupton, J.T.4
-
140
-
-
0034093210
-
Fluorine sacrificial cyclizations as an access to 5-fluoropyr-azoles
-
Volle, J.-N.; Schlosser, M. Fluorine sacrificial cyclizations as an access to 5-fluoropyr-azoles. Eur. J. Org. Chem. 2000, 823-828.
-
(2000)
Eur. J. Org. Chem
, pp. 823-828
-
-
Volle, J.-N.1
Schlosser, M.2
-
141
-
-
18044386780
-
Palladium catalyzed cross-coupling reaction of 5-tributylstannyl-4-fluoropyrazole
-
Hanamoto, T.; Koga, Y.; Kido, E.; Kawanami, T.; Furuno, H.; Inanaga, J. Palladium catalyzed cross-coupling reaction of 5-tributylstannyl-4-fluoropyrazole. Chem. Com-mun. 2005, 2041-2043.
-
(2005)
Chem. Com-mun
, pp. 2041-2043
-
-
Hanamoto, T.1
Koga, Y.2
Kido, E.3
Kawanami, T.4
Furuno, H.5
Inanaga, J.6
-
142
-
-
34247616772
-
Synthesis and reactions of 5-tributylstannyl-4-fluoro-1H-pyrazoles
-
Hanamoto, T.; Suetake, T.; Koga, Y.; Kawanami, T.; Furuno, H.; Inanaga, J. Synthesis and reactions of 5-tributylstannyl-4-fluoro-1H-pyrazoles. Tetrahedron 2007, 63, 5062-5070.
-
(2007)
Tetrahedron
, vol.63
, pp. 5062-5070
-
-
Hanamoto, T.1
Suetake, T.2
Koga, Y.3
Kawanami, T.4
Furuno, H.5
Inanaga, J.6
-
143
-
-
33745276289
-
Estrogen receptor ß-subtype selective tetrahydrofluorenones: use of a fused pyrazole as phenol bioisostere
-
Wilkening, R.R.; Ratcliffe, R.W.; Fried, A.K.; Meng, D.; Sun, W.; Colwell, L.; Lambert, S.; Grennlee, M.; Nilsson, S.; Thorsell, A.; Mojena, M.; Tudela, C.; Frisch, K.; Chan, W.; Birzin, E.T.; Rohrer, S.P.; Hammond, M.L. Estrogen receptor ß-subtype selective tetrahydrofluorenones: use of a fused pyrazole as phenol bioisostere. Bioorg. Med. Chem. Lett. 2006, 16, 3896-3901.
-
(2006)
Bioorg. Med. Chem. Lett
, vol.16
, pp. 3896-3901
-
-
Wilkening, R.R.1
Ratcliffe, R.W.2
Fried, A.K.3
Meng, D.4
Sun, W.5
Colwell, L.6
Lambert, S.7
Grennlee, M.8
Nilsson, S.9
Thorsell, A.10
Mojena, M.11
Tudela, C.12
Frisch, K.13
Chan, W.14
Birzin, E.T.15
Rohrer, S.P.16
Hammond, M.L.17
-
144
-
-
14844315918
-
Fluorinated phenylcyclopropy-lamines. Part 4: effects of aryl substituents and stereochemistry on the inhibition of monoamine oxidase by 1-aryl-2-fluoro-cyclopropylamines
-
Ye, S.; Yoshida, S.; Frülich, R.; Haufe, G.; Kirk, K.L. Fluorinated phenylcyclopropy-lamines. Part 4: effects of aryl substituents and stereochemistry on the inhibition of monoamine oxidase by 1-aryl-2-fluoro-cyclopropylamines. Bioorg. Med. Chem. 2005, 13, 2489-2499.
-
(2005)
Bioorg. Med. Chem
, vol.13
, pp. 2489-2499
-
-
Ye, S.1
Yoshida, S.2
Frülich, R.3
Haufe, G.4
Kirk, K.L.5
-
145
-
-
0019448653
-
Preparation and reactivity of an a-(difluoromethylene)-g-lactone
-
Suda, M. Preparation and reactivity of an a-(difluoromethylene)-g-lactone. Tetrahedron Lett. 1981, 22, 1421-1424.
-
(1981)
Tetrahedron Lett
, vol.22
, pp. 1421-1424
-
-
Suda, M.1
-
146
-
-
4043058688
-
An efficient preparation of novel 5-fluoropyrazolin-3-one derivatives from a-trifluoromethylated a-arylacetates
-
Park, N.K.; Kim, B.T.; Moon, S.S.; Jeon, S.L.; Jeong, I.H. An efficient preparation of novel 5-fluoropyrazolin-3-one derivatives from a-trifluoromethylated a-arylacetates. Tetrahedron 2004, 60, 7943-7949.
-
(2004)
Tetrahedron
, vol.60
, pp. 7943-7949
-
-
Park, N.K.1
Kim, B.T.2
Moon, S.S.3
Jeon, S.L.4
Jeong, I.H.5
-
147
-
-
33749253109
-
Synthesis of celecoxib via 1, 3-dipolar cycloaddition
-
Oh, L.M. Synthesis of celecoxib via 1, 3-dipolar cycloaddition. Tetrahedron Lett. 2006, 47, 7943-7946.
-
(2006)
Tetrahedron Lett
, vol.47
, pp. 7943-7946
-
-
Oh, L.M.1
-
148
-
-
0035188179
-
Synthesis of fluorinated pyrazole derivatives from ß-alkoxyvinyl trifluoroketones
-
Song, L.-p.; Chu, Q.-l.; Zhu, S.-z. Synthesis of fluorinated pyrazole derivatives from ß-alkoxyvinyl trifluoroketones. J. Fluorine Chem. 2001, 107, 107-112.
-
(2001)
J. Fluorine Chem
, vol.107
, pp. 107-112
-
-
Song, L.-P.1
Chu, Q.-L.2
Zhu, S.-Z.3
-
149
-
-
0034813595
-
Regioselective synthesis of fluorinated pyrazole derivatives from trifluormethyl-1, 3-diketone
-
Song, L.-p.; Zhu, S.-z. Regioselective synthesis of fluorinated pyrazole derivatives from trifluormethyl-1, 3-diketone. J. Fluorine Chem. 2001, 111, 201-205.
-
(2001)
J. Fluorine Chem
, vol.111
, pp. 201-205
-
-
Song, L.-P.1
Zhu, S.-Z.2
-
150
-
-
34848859255
-
Synthesis of pentafluorosulfanylpyrazole and pentafluorosulfanyl-1, 2, 3-triazole and their derivatives as energetic materials by click chemistry
-
Ye, C.; Gard, G.L.; Winter, R.W.; Syvret, R.G.; Twamley, B.; Shreeve, J.M. Synthesis of pentafluorosulfanylpyrazole and pentafluorosulfanyl-1, 2, 3-triazole and their derivatives as energetic materials by click chemistry. Org. Lett. 2007, 9, 3841-3844.
-
(2007)
Org. Lett
, vol.9
, pp. 3841-3844
-
-
Ye, C.1
Gard, G.L.2
Winter, R.W.3
Syvret, R.G.4
Twamley, B.5
Shreeve, J.M.6
-
151
-
-
0015923354
-
A novelrouteto 3(5)-fluoro-1, 2, 4-triazoles and 8-fluoropurines by displacement of the nitro group
-
Naik, S.R.; Witkowski, J.T.; Robins, R.K. A novelrouteto 3(5)-fluoro-1, 2, 4-triazoles and 8-fluoropurines by displacement of the nitro group. J. Org. Chem. 1973, 38, 14353-4354.
-
(1973)
J. Org. Chem
, vol.38
, pp. 14353-14354
-
-
Naik, S.R.1
Witkowski, J.T.2
Robins, R.K.3
-
152
-
-
0006236186
-
Sintesis de fluoroazoles
-
Vilarrasa, J.; Galvez, C.; Calafell, M. Sintesis de fluoroazoles. An. Quim. 1975, 71, 631-633.
-
(1975)
An. Quim
, vol.71
, pp. 631-633
-
-
Vilarrasa, J.1
Galvez, C.2
Calafell, M.3
-
153
-
-
0031660602
-
The first versatile synthesis of 1-alkyl-3-fluoro 1H-[1, 2, 4]-triazoles
-
Zumbrunn, A. The first versatile synthesis of 1-alkyl-3-fluoro 1H-[1, 2, 4]-triazoles. Synthesis 1998, 1357-1361.
-
(1998)
Synthesis
, pp. 1357-1361
-
-
Zumbrunn, A.1
-
154
-
-
0037462414
-
Fluorinated heterocyclic compounds. An expedient route to 4-perfluoroalkyl-1, 2, 4-triazoles via an unusual hydrazinolysis of 5-perfluoroalkyl-1, 2, 4-oxadiazoles: first examples of an ANRORC-like reaction in 1, 2, 4-oxadiazole derivatives
-
Buscemi, S.; Pace, A.; Pibiri, I.; Vivona, N.; Spinelli, D. Fluorinated heterocyclic compounds. An expedient route to 4-perfluoroalkyl-1, 2, 4-triazoles via an unusual hydrazinolysis of 5-perfluoroalkyl-1, 2, 4-oxadiazoles: first examples of an ANRORC-like reaction in 1, 2, 4-oxadiazole derivatives. J. Org. Chem. 2003, 68, 605-608.
-
(2003)
J. Org. Chem
, vol.68
, pp. 605-608
-
-
Buscemi, S.1
Pace, A.2
Pibiri, I.3
Vivona, N.4
Spinelli, D.5
-
155
-
-
11144253374
-
A direct and general synthesis of 5-substituted 3-trifluoromethyl-1, 2, 4-triazoles via the three component condensation reaction of ethyl trifluoroacetate, hydrazine and amidines
-
1999
-
Funabike, K.; Noma, N.; Kuzuya, G.; Matusi, M.; Shibata, K. A direct and general synthesis of 5-substituted 3-trifluoromethyl-1, 2, 4-triazoles via the three component condensation reaction of ethyl trifluoroacetate, hydrazine and amidines. J. Chem. Res. Synop. 1999, 300-301, 1999, 1301-1308.
-
(1999)
J. Chem. Res. Synop
, vol.300-301
, pp. 1301-1308
-
-
Funabike, K.1
Noma, N.2
Kuzuya, G.3
Matusi, M.4
Shibata, K.5
-
156
-
-
1242352422
-
The first 1-aLkyl-3-perfluoroaLkyl-4, 5-dimethyl-1, 2, 4-triazolium salts
-
Xue, H.; Twamley, B.; Shreeve, J.M. The first 1-aLkyl-3-perfluoroaLkyl-4, 5-dimethyl-1, 2, 4-triazolium salts. J. Org. Chem. 2004, 69, 1397-1400.
-
(2004)
J. Org. Chem
, vol.69
, pp. 1397-1400
-
-
Xue, H.1
Twamley, B.2
Shreeve, J.M.3
-
157
-
-
2942588783
-
Photochemistry of fluorinated heterocyclic compounds. An expedient route for the synthesis of fluorinated 1, 2, 4-oxadizoles and 1, 2, 4-triazoles
-
Pace, A.; Pibiri, I.; Buscemi, S.; Vivona, N. Photochemistry of fluorinated heterocyclic compounds. An expedient route for the synthesis of fluorinated 1, 2, 4-oxadizoles and 1, 2, 4-triazoles. J. Org. Chem. 2004, 69, 4108-4115.
-
(2004)
J. Org. Chem
, vol.69
, pp. 4108-4115
-
-
Pace, A.1
Pibiri, I.2
Buscemi, S.3
Vivona, N.4
-
158
-
-
0030798711
-
Selectivity and mode of action of carfentrazone-ethyl, a novel phenyl triazolinone herbicide
-
Dayan, F.E.; Duke, S.O.; Weete, J.D.; Hancock, H.G. Selectivity and mode of action of carfentrazone-ethyl, a novel phenyl triazolinone herbicide. Pestic. Sci. 1997, 51, 65-73.
-
(1997)
Pestic. Sci
, vol.51
, pp. 65-73
-
-
Dayan, F.E.1
Duke, S.O.2
Weete, J.D.3
Hancock, H.G.4
-
159
-
-
84891042800
-
Agricultural products based on fluorinated heterocyclic compounds
-
In, Petrov, V.A., Ed.; Wiley-Blackwell: New York, p xx
-
Hong, W. Agricultural products based on fluorinated heterocyclic compounds. In Fluorinated Heterocyclic Compounds; Petrov, V.A., Ed.; Wiley-Blackwell: New York, 2008; p xx.
-
(2008)
Fluorinated Heterocyclic Compounds
-
-
Hong, W.1
-
160
-
-
37049134095
-
Organosilicon chemistry. Part X. Reaction of (diazomethyl)trimethylsilane with trifluoroacetonitrile and cyanaogen halides to give triazoles
-
Crossman, J.M.; Haszledine, R.N.; Tipping, A.E. Organosilicon chemistry. Part X. Reaction of (diazomethyl)trimethylsilane with trifluoroacetonitrile and cyanaogen halides to give triazoles. J. Chem. Soc. 1973, 483-486.
-
(1973)
J. Chem. Soc
, pp. 483-486
-
-
Crossman, J.M.1
Haszledine, R.N.2
Tipping, A.E.3
-
161
-
-
37049100785
-
Polyhalogeno-allenes and-acetylenes. Part 15. Dipolar cycloadditions of N-phenylsydnone and aryl azides to perfluoropropa-diene and perfluoropropyne
-
Blackwell, G.B.; Haszeldine, R.N.; Taylor, D.R. Polyhalogeno-allenes and-acetylenes. Part 15. Dipolar cycloadditions of N-phenylsydnone and aryl azides to perfluoropropa-diene and perfluoropropyne. J. Chem. Soc., Perkin Trans. 1 1982, 2207-2210.
-
(1982)
J. Chem. Soc., Perkin Trans. 1
, pp. 2207-2210
-
-
Blackwell, G.B.1
Haszeldine, R.N.2
Taylor, D.R.3
-
162
-
-
12344293492
-
Identification of 4-substituted 1, 2, 3-trriazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase-A
-
Reck, F.; Zhou, F.; Girardot, M.; Kern, G.; Eyermann, C.J.; Hales, N.J.; Ramsay, R.R.; Gravestock, M.B. Identification of 4-substituted 1, 2, 3-trriazoles as novel oxazolidinone antibacterial agents with reduced activity against monoamine oxidase-A. J. Med. Chem. 2005, 48, 499-506.
-
(2005)
J. Med. Chem
, vol.48
, pp. 499-506
-
-
Reck, F.1
Zhou, F.2
Girardot, M.3
Kern, G.4
Eyermann, C.J.5
Hales, N.J.6
Ramsay, R.R.7
Gravestock, M.B.8
-
163
-
-
0001024688
-
Aryltrifluoromethyl-1, 2, 3-triazoles
-
Meazza, G.; Zanardi, G. Aryltrifluoromethyl-1, 2, 3-triazoles. J. Fluorine Chem. 1991, 55, 199-206.
-
(1991)
J. Fluorine Chem
, vol.55
, pp. 199-206
-
-
Meazza, G.1
Zanardi, G.2
-
164
-
-
0002627128
-
Organofluorine compounds and fluorinating agents. Part 26. New reversed nucleosides-perfluoroalkyl substituted 1, 2, 3-triazoles linked to d-galactose and d-altrose
-
Hager, C.; Miethchen, R.; Reinke, H. Organofluorine compounds and fluorinating agents. Part 26. New reversed nucleosides-perfluoroalkyl substituted 1, 2, 3-triazoles linked to d-galactose and d-altrose. J. Fluorine Chem. 2000, 104, 135-142.
-
(2000)
J. Fluorine Chem
, vol.104
, pp. 135-142
-
-
Hager, C.1
Miethchen, R.2
Reinke, H.3
-
165
-
-
0348237063
-
Organofluorine compounds and fluorinating agents. 27. New trifluoromethyl substituted 1, 2, 3-triazoles linked to d-galactose and d-gulose
-
Hager, C.; Miethchen, R.; Reinke, H. Organofluorine compounds and fluorinating agents. 27. New trifluoromethyl substituted 1, 2, 3-triazoles linked to d-galactose and d-gulose. J. Prakt. Chem. 2000, 342, 414-420.
-
(2000)
J. Prakt. Chem
, vol.342
, pp. 414-420
-
-
Hager, C.1
Miethchen, R.2
Reinke, H.3
-
166
-
-
0006644846
-
Perfluoralkylsubstituierte ß-Chlorvinylaldehyde: eine neue Klasse von building blocks zur Synthese fluorierter Heterocyclen
-
Greif, D.; Eilitz, U.; Pulst, M.; Riedel, D.; Wecks, M. Perfluoralkylsubstituierte ß-Chlorvinylaldehyde: eine neue Klasse von building blocks zur Synthese fluorierter Heterocyclen. J. Fluorine Chem. 1999, 94, 91-103.
-
(1999)
J. Fluorine Chem
, vol.94
, pp. 91-103
-
-
Greif, D.1
Eilitz, U.2
Pulst, M.3
Riedel, D.4
Wecks, M.5
-
167
-
-
33750602935
-
Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1, 2, 3-triazole derivatives
-
Costa, M.S.; Boechat, N.; Rangel, E.A.; da Silva, F.d.C.; de Sousa A.M.T.; Rodrigues, C. R.; Castro, H.C.; Junior, I.N.; Lourenco, M.C.S.; Wardell, S.M.S.V.; Ferreira, V.F. Synthesis, tuberculosis inhibitory activity, and SAR study of N-substituted-phenyl-1, 2, 3-triazole derivatives. Bioorg. Med. Chem. 2006, 14, 8644-8653.
-
(2006)
Bioorg. Med. Chem
, vol.14
, pp. 8644-8653
-
-
Costa, M.S.1
Boechat, N.2
Rangel, E.A.3
Da Silva, F.D.C.4
De Sousa, A.M.T.5
Rodrigues, C.R.6
Castro, H.C.7
Junior, I.N.8
Lourenco, M.C.S.9
Wardell, S.M.S.V.10
Ferreira, V.F.11
-
168
-
-
0039794753
-
Synthese de N-(tetrazol-5-yl) azetidin-2-ones
-
Klich, M.; Teutsch, G. Synthese de N-(tetrazol-5-yl) azetidin-2-ones. Tetrahedron 1986, 42, 2677-2684.
-
(1986)
Tetrahedron
, vol.42
, pp. 2677-2684
-
-
Klich, M.1
Teutsch, G.2
-
169
-
-
0008572930
-
5-Trifluoromethyltetrazole and its derivatives
-
Norris, W.P. 5-Trifluoromethyltetrazole and its derivatives. J. Org. Chem. 1962, 27, 3248-3251.
-
(1962)
J. Org. Chem
, vol.27
, pp. 3248-3251
-
-
Norris, W.P.1
-
170
-
-
0038723870
-
5-Perfluoroalkyltetrazoles. 1. Ring-opening reactions
-
Brown, H.C.; Kassal, R.J. 5-Perfluoroalkyltetrazoles. 1. Ring-opening reactions. J. Org. Chem. 1967, 32, 1871-1873.
-
(1967)
J. Org. Chem
, vol.32
, pp. 1871-1873
-
-
Brown, H.C.1
Kassal, R.J.2
-
171
-
-
0005466944
-
Synthesis of trifluoromethyltetrazoles via building block strategy
-
Xiao, J.; Zhang, X.; Wang, D.; Yuan, C. Synthesis of trifluoromethyltetrazoles via building block strategy. J. Fluorine Chem. 1999, 99, 83-85.
-
(1999)
J. Fluorine Chem
, vol.99
, pp. 83-85
-
-
Xiao, J.1
Zhang, X.2
Wang, D.3
Yuan, C.4
-
172
-
-
17044461438
-
1 receptor antagonists: the identification of an exceptionally potent orally active antiemetic compound
-
1 receptor antagonists: the identification of an exceptionally potent orally active antiemetic compound. Bioorg. Med. Chem. Lett. 1996, 6, 1015-1020.
-
(1996)
Bioorg. Med. Chem. Lett
, vol.6
, pp. 1015-1020
-
-
Armour, D.R.1
Chung, K.M.L.2
Congreve, M.3
Evans, B.4
Guntrip, S.5
Hubbard, T.6
Kay, C.7
Middlemiss, D.8
Mordaunt, J.E.9
Pegg, N.A.10
Vinader, M.V.11
Ward, P.12
Watson, S.P.13
-
173
-
-
0347517811
-
The difluoromethylene group as a replacement for the labile oxygen in steroid sulfates: a new approach to steroid sulfatase inhibitors
-
Lapierre, J.; Ahmed, V.; Chen, M.-J.; Ispahany, M.; Guillemette, J.G.; Taylor, S.D. The difluoromethylene group as a replacement for the labile oxygen in steroid sulfates: a new approach to steroid sulfatase inhibitors. Bioorg. Med. Chem. Lett. 2004, 14, 151-155.
-
(2004)
Bioorg. Med. Chem. Lett
, vol.14
, pp. 151-155
-
-
Lapierre, J.1
Ahmed, V.2
Chen, M.-J.3
Ispahany, M.4
Guillemette, J.G.5
Taylor, S.D.6
-
174
-
-
0003536898
-
Organofluorine Chemistry. Principles and Commercial Applications
-
Eds., Plenum Press: New York
-
Banks, R.E.; Smart, B.E.; Tatlow, J.C., Eds.; Organofluorine Chemistry. Principles and Commercial Applications; Plenum Press: New York, 1994.
-
(1994)
-
-
Banks, R.E.1
Smart, B.E.2
Tatlow, J.C.3
-
175
-
-
0000939652
-
Nucleophilic reactions of fluoroolefins
-
England, D.C.; Melby, L.R.; Dietrich, M.A.; Lindsey, R.V., Jr. Nucleophilic reactions of fluoroolefins. J. Am. Chem. Soc. 1960, 82, 5116-5122.
-
(1960)
J. Am. Chem. Soc
, vol.82
, pp. 5116-5122
-
-
England, D.C.1
Melby, L.R.2
Dietrich, M.A.3
Lindsey Jr., R.V.4
-
176
-
-
33745300176
-
Interaction of the azole N-sodium derivatives with Freon-113: synthesis of N-(2, 2-dichlorotrifluoroethyl)azoles
-
Petko, K.I.; Yagupolskii, L.M. Interaction of the azole N-sodium derivatives with Freon-113: synthesis of N-(2, 2-dichlorotrifluoroethyl)azoles. Synth. Commun. 2006, 36, 1967-1972.
-
(2006)
Synth. Commun
, vol.36
, pp. 1967-1972
-
-
Petko, K.I.1
Yagupolskii, L.M.2
-
177
-
-
33845506639
-
Chemical properties of N-difluoro-methyl-and N-2-H-tetrafluoroethylypyrazoles
-
Petko, K.I.; Sokolenko, T.M.; Yagupolskii, L.M. Chemical properties of N-difluoro-methyl-and N-2-H-tetrafluoroethylypyrazoles. Chem. Heterocycl. Comp. 2006, 42, 1177-1184.
-
(2006)
Chem. Heterocycl. Comp
, vol.42
, pp. 1177-1184
-
-
Petko, K.I.1
Sokolenko, T.M.2
Yagupolskii, L.M.3
-
178
-
-
25144514490
-
Chemical properties of N-polyfluor-oethylimidazole and-pyrrole derivatives
-
Yagupolskii, L.M.; Sokolenko, T.M.; Petko, K.I. Chemical properties of N-polyfluor-oethylimidazole and-pyrrole derivatives. Russ. Chem. Bull., Int. Ed. 2005, 54, 796-802.
-
(2005)
Russ. Chem. Bull., Int. Ed
, vol.54
, pp. 796-802
-
-
Yagupolskii, L.M.1
Sokolenko, T.M.2
Petko, K.I.3
-
179
-
-
4644280536
-
N-Polyfluoroethyl and N-2-chlorodi-fluorovinyl derivatives of azoles
-
Rudyuk, V.V.; Fedyuk, D.V.; Yagupolskii, L.V. N-Polyfluoroethyl and N-2-chlorodi-fluorovinyl derivatives of azoles. J. Fluorine Chem. 2004, 125, 1465-1471.
-
(2004)
J. Fluorine Chem
, vol.125
, pp. 1465-1471
-
-
Rudyuk, V.V.1
Fedyuk, D.V.2
Yagupolskii, L.V.3
-
180
-
-
26444553617
-
N-(2-Bromotetrafluor-oethyl) derivatives of five-membered nitrogen-containing heterocycles
-
Petko, K.I.; Sokolenko, T.M.; Bezdudny, A.V.; Yagupolskii, L.M. N-(2-Bromotetrafluor-oethyl) derivatives of five-membered nitrogen-containing heterocycles. J. Fluorine Chem. 2005, 126, 1342-1346.
-
(2005)
J. Fluorine Chem
, vol.126
, pp. 1342-1346
-
-
Petko, K.I.1
Sokolenko, T.M.2
Bezdudny, A.V.3
Yagupolskii, L.M.4
-
182
-
-
0010135252
-
Synthesis of perflourochemicals as blood substitutes. Part IV. Electrochemical fluorina-tion of N-cycloalkyl-pyrrolidines and-piperidines
-
Ono, T.; Inoue, Y.; Arakawa, Y.; Naito, Y.; Fukaya, C.; Yamanouchi, K.; Yokoyama, K. Synthesis of perflourochemicals as blood substitutes. Part IV. Electrochemical fluorina-tion of N-cycloalkyl-pyrrolidines and-piperidines. J. Fluorine Chem. 1989, 43, 67-85.
-
(1989)
J. Fluorine Chem
, vol.43
, pp. 67-85
-
-
Ono, T.1
Inoue, Y.2
Arakawa, Y.3
Naito, Y.4
Fukaya, C.5
Yamanouchi, K.6
Yokoyama, K.7
-
183
-
-
0001381758
-
The electrochemical fluorination of nitrogen-containing carboxylic acids. Fluorination of methyl esters of cyclic amino-group substituted carboxylic acids
-
and references therein
-
Abe, T.; Hayashi, E.; Fukaya, H.; Baba, H. The electrochemical fluorination of nitrogen-containing carboxylic acids. Fluorination of methyl esters of cyclic amino-group substituted carboxylic acids. J. Fluorine Chem. 1990, 50, 173-176, and references therein.
-
(1990)
J. Fluorine Chem
, vol.50
, pp. 173-176
-
-
Abe, T.1
Hayashi, E.2
Fukaya, H.3
Baba, H.4
-
184
-
-
0000238771
-
The electrochemical fluorination of nitrogen-containing carboxylic acids. Fluorination of methyl esters of 3-dialkylamino propionic acids
-
and references therein
-
Abe, T.; Hayashi, E.; Fukaya, H.; Hayakawa, Y.; Baba, H.; Ishikawa, S.; Asahino, K. The electrochemical fluorination of nitrogen-containing carboxylic acids. Fluorination of methyl esters of 3-dialkylamino propionic acids. J. Fluorine Chem. 1992, 57, 101-111, and references therein.
-
(1992)
J. Fluorine Chem
, vol.57
, pp. 101-111
-
-
Abe, T.1
Hayashi, E.2
Fukaya, H.3
Hayakawa, Y.4
Baba, H.5
Ishikawa, S.6
Asahino, K.7
-
185
-
-
0041978331
-
Electrochemical fluorination of (N, N-dialkylamino)alcohols
-
and references therein
-
Abe, T.; Fukaya, H.; Hayashi, E.; Ono, T.; Nishida, M.; Soloshonok, I.; Okuhara, K. Electrochemical fluorination of (N, N-dialkylamino)alcohols. J. Fluorine Chem. 1999, 97, 229-237, and references therein.
-
(1999)
J. Fluorine Chem
, vol.97
, pp. 229-237
-
-
Abe, T.1
Fukaya, H.2
Hayashi, E.3
Ono, T.4
Nishida, M.5
Soloshonok, I.6
Okuhara, K.7
|