Tetrazole NK1 receptor antagonists: The identification of an exceptionally potent orally active antiemetic compound

Bioorganic and Medicinal Chemistry Letters

Volumn 6, Issue 9, 1996, Pages 1015-1020

  Armour, D R ^a   Chung, K M L ^a   Congreve, M ^a   Evans, B ^a   Guntrip, S ^a   Hubbard, T ^a   Kay, C ^a   Middlemiss, D ^a   Mordaunt, J E ^a   Pegg, N A ^a   Vinader, M V ^a   Ward, P ^a   Watson, S P ^a  

^a GLAXOSMITHKLINE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIEMETIC AGENT; NEUROKININ 1 RECEPTOR ANTAGONIST; UNCLASSIFIED DRUG; VOFOPITANT; [2 METHOXY 5 (1 TETRAZOLYL)BENZYL](2 PHENYL 3 PIPERIDINYL)AMINE;

ANIMAL CELL; ANIMAL MODEL; ARTICLE; CHO CELL; CONTROLLED STUDY; DRUG DESIGN; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; FERRET; NONHUMAN; RADIATION; SUBCUTANEOUS DRUG ADMINISTRATION; VOMITING;

EID: 17044461438     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/0960-894X(96)00163-1     Document Type: Article

References (14)

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