Effect of 2-fluorohistidine labeling of the anthrax protective antigen on stability, pore formation, and translocation

Biochemistry

Volumn 46, Issue 51, 2007, Pages 14928-14936

  Wimalasena, D Shyamali ^a   Cramer, John C ^b   Janowiak, Blythe E ^c   Juris, Stephen J ^c,d   Melnyk, Roman A ^c,e   Anderson, D Eric ^b   Kirk, Kenneth L ^b   Collier, R John ^c   Bann, James G ^a  

^a WICHITA STATE UNIVERSITY   (United States)

^b NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

^d CENTRAL MICHIGAN UNIVERSITY   (United States)

^e MERCK FROSST CENTRE FOR THERAPEUTIC RESEARCH   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOSOMAL MEMBRANE; FLUOROHISTIDINE LABELING; HISTIDINE; PORE FORMATION;

AMINO ACIDS; ANTIGENS; BIOSYNTHESIS; CONFORMATIONS; LIPOSOMES; PROTONATION;

DRUG PRODUCTS;

2 FLUOROHISTIDINE; ANTHRAX TOXIN; ASPARTIC ACID; GLUTAMIC ACID; HISTIDINE DERIVATIVE; LIPOSOME; POTASSIUM; PROTECTIVE ANTIGEN; TRYPSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN FUNCTION; ARTICLE; BILAYER MEMBRANE; CHANNEL GATING; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ELECTRIC POTENTIAL; ENDOSOME; NONHUMAN; PH; PKA; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN STABILITY; PROTEIN SYNTHESIS; PROTON TRANSPORT;

ANIMALS; ANTIGENS, BACTERIAL; BACTERIAL TOXINS; CELL MEMBRANE; CHO CELLS; CIRCULAR DICHROISM; CRICETINAE; CRICETULUS; ELECTROPHORESIS, POLYACRYLAMIDE GEL; HISTIDINE; HYDROGEN-ION CONCENTRATION; MODELS, MOLECULAR; PROTEIN DENATURATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT;

EID: 37349043646     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi701763z     Document Type: Article

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