-
1
-
-
77958196417
-
Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition
-
Bachmann P.S., Piazza R.G., Janes M.E., Wong N.C., Davies C., Mogavero A., Bhadri V.A., Szymanska B., Geninson G., Magistroni V., Cazzaniga G., Biondi A., Miranda-Saavedra D., Gottgens B., Saffery R., Craig J.M., Marshall G.M., Gambacorti-Passerini C., Pimanda J.E., Lock R.B. Epigenetic silencing of BIM in glucocorticoid poor-responsive pediatric acute lymphoblastic leukemia, and its reversal by histone deacetylase inhibition. Blood 2010, 116:3013-3022.
-
(2010)
Blood
, vol.116
, pp. 3013-3022
-
-
Bachmann, P.S.1
Piazza, R.G.2
Janes, M.E.3
Wong, N.C.4
Davies, C.5
Mogavero, A.6
Bhadri, V.A.7
Szymanska, B.8
Geninson, G.9
Magistroni, V.10
Cazzaniga, G.11
Biondi, A.12
Miranda-Saavedra, D.13
Gottgens, B.14
Saffery, R.15
Craig, J.M.16
Marshall, G.M.17
Gambacorti-Passerini, C.18
Pimanda, J.E.19
Lock, R.B.20
more..
-
2
-
-
79952350938
-
Role for histone deacetylase 3 in maintenance of genome stability
-
Bhaskara S., Hiebert S.W. Role for histone deacetylase 3 in maintenance of genome stability. Cell Cycle 2011, 10:727-728.
-
(2011)
Cell Cycle
, vol.10
, pp. 727-728
-
-
Bhaskara, S.1
Hiebert, S.W.2
-
3
-
-
68949170694
-
3,3'-Diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin
-
Bhatnagar N., Li X., Chen Y., Zhou X., Garrett S.H., Guo B. 3,3'-Diindolylmethane enhances the efficacy of butyrate in colon cancer prevention through down-regulation of survivin. Cancer Prev. Res. (Phila. Pa.) 2009, 2:581-589.
-
(2009)
Cancer Prev. Res. (Phila. Pa.)
, vol.2
, pp. 581-589
-
-
Bhatnagar, N.1
Li, X.2
Chen, Y.3
Zhou, X.4
Garrett, S.H.5
Guo, B.6
-
4
-
-
4544358659
-
Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development
-
Chang S., McKinsey T.A., Zhang C.L., Richardson J.A., Hill J.A., Olson E.N. Histone deacetylases 5 and 9 govern responsiveness of the heart to a subset of stress signals and play redundant roles in heart development. Mol. Cell. Biol. 2004, 24:8467-8476.
-
(2004)
Mol. Cell. Biol.
, vol.24
, pp. 8467-8476
-
-
Chang, S.1
McKinsey, T.A.2
Zhang, C.L.3
Richardson, J.A.4
Hill, J.A.5
Olson, E.N.6
-
5
-
-
84857365823
-
DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs
-
Charlet J., Schnekenburger M., Brown K.W., Diederich M. DNA demethylation increases sensitivity of neuroblastoma cells to chemotherapeutic drugs. Biochem. Pharmacol. 2012, 83:858-865.
-
(2012)
Biochem. Pharmacol.
, vol.83
, pp. 858-865
-
-
Charlet, J.1
Schnekenburger, M.2
Brown, K.W.3
Diederich, M.4
-
6
-
-
0037444803
-
Histone deacetylases (HDACs): characterization of the classical HDAC family
-
de Ruijter A.J., van Gennip A.H., Caron H.N., Kemp S., van Kuilenburg A.B. Histone deacetylases (HDACs): characterization of the classical HDAC family. Biochem. J. 2003, 370:737-749.
-
(2003)
Biochem. J.
, vol.370
, pp. 737-749
-
-
de Ruijter, A.J.1
van Gennip, A.H.2
Caron, H.N.3
Kemp, S.4
van Kuilenburg, A.B.5
-
7
-
-
3242755145
-
Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines
-
Druesne N., Pagniez A., Mayeur C., Thomas M., Cherbuy C., Duee P.H., Martel P., Chaumontet C. Diallyl disulfide (DADS) increases histone acetylation and p21(waf1/cip1) expression in human colon tumor cell lines. Carcinogenesis 2004, 25:1227-1236.
-
(2004)
Carcinogenesis
, vol.25
, pp. 1227-1236
-
-
Druesne, N.1
Pagniez, A.2
Mayeur, C.3
Thomas, M.4
Cherbuy, C.5
Duee, P.H.6
Martel, P.7
Chaumontet, C.8
-
8
-
-
80054734934
-
Epigenomics of leukemia: from mechanisms to therapeutic applications
-
Florean C., Schnekenburger M., Grandjenette C., Dicato M., Diederich M. Epigenomics of leukemia: from mechanisms to therapeutic applications. Epigenomics 2011, 3:581-609.
-
(2011)
Epigenomics
, vol.3
, pp. 581-609
-
-
Florean, C.1
Schnekenburger, M.2
Grandjenette, C.3
Dicato, M.4
Diederich, M.5
-
9
-
-
77949705465
-
Naturally occurring regulators of histone acetylation/deacetylation
-
Folmer F., Orlikova B., Schnekenburger M., Dicato M., Diederich M. Naturally occurring regulators of histone acetylation/deacetylation. Curr. Nutr. Food Sci. 2010, 6:78-99.
-
(2010)
Curr. Nutr. Food Sci.
, vol.6
, pp. 78-99
-
-
Folmer, F.1
Orlikova, B.2
Schnekenburger, M.3
Dicato, M.4
Diederich, M.5
-
10
-
-
0036735385
-
FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases
-
Furumai R., Matsuyama A., Kobashi N., Lee K.H., Nishiyama M., Nakajima H., Tanaka A., Komatsu Y., Nishino N., Yoshida M., Horinouchi S. FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases. Cancer Res. 2002, 62:4916-4921.
-
(2002)
Cancer Res.
, vol.62
, pp. 4916-4921
-
-
Furumai, R.1
Matsuyama, A.2
Kobashi, N.3
Lee, K.H.4
Nishiyama, M.5
Nakajima, H.6
Tanaka, A.7
Komatsu, Y.8
Nishino, N.9
Yoshida, M.10
Horinouchi, S.11
-
11
-
-
0842277812
-
Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1
-
Gui C.Y., Ngo L., Xu W.S., Richon V.M., Marks P.A. Histone deacetylase (HDAC) inhibitor activation of p21WAF1 involves changes in promoter-associated proteins, including HDAC1. Proc. Natl. Acad. Sci. USA 2004, 101:1241-1246.
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 1241-1246
-
-
Gui, C.Y.1
Ngo, L.2
Xu, W.S.3
Richon, V.M.4
Marks, P.A.5
-
12
-
-
80054881600
-
Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin
-
Kaluza D., Kroll J., Gesierich S., Yao T.P., Boon R.A., Hergenreider E., Tjwa M., Rossig L., Seto E., Augustin H.G., Zeiher A.M., Dimmeler S., Urbich C. Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin. EMBO J. 2011, 30:4142-4156.
-
(2011)
EMBO J.
, vol.30
, pp. 4142-4156
-
-
Kaluza, D.1
Kroll, J.2
Gesierich, S.3
Yao, T.P.4
Boon, R.A.5
Hergenreider, E.6
Tjwa, M.7
Rossig, L.8
Seto, E.9
Augustin, H.G.10
Zeiher, A.M.11
Dimmeler, S.12
Urbich, C.13
-
13
-
-
79955610018
-
Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines
-
Karius T., Schnekenburger M., Ghelfi J., Walter J., Dicato M., Diederich M. Reversible epigenetic fingerprint-mediated glutathione-S-transferase P1 gene silencing in human leukemia cell lines. Biochem. Pharmacol. 2011, 81:1329-1342.
-
(2011)
Biochem. Pharmacol.
, vol.81
, pp. 1329-1342
-
-
Karius, T.1
Schnekenburger, M.2
Ghelfi, J.3
Walter, J.4
Dicato, M.5
Diederich, M.6
-
14
-
-
34250810709
-
Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells
-
Kumagai T., Wakimoto N., Yin D., Gery S., Kawamata N., Takai N., Komatsu N., Chumakov A., Imai Y., Koeffler H.P. Histone deacetylase inhibitor, suberoylanilide hydroxamic acid (Vorinostat, SAHA) profoundly inhibits the growth of human pancreatic cancer cells. International Journal of Cancer. Journal International du Cancer 2007, 121:656-665.
-
(2007)
International Journal of Cancer. Journal International du Cancer
, vol.121
, pp. 656-665
-
-
Kumagai, T.1
Wakimoto, N.2
Yin, D.3
Gery, S.4
Kawamata, N.5
Takai, N.6
Komatsu, N.7
Chumakov, A.8
Imai, Y.9
Koeffler, H.P.10
-
15
-
-
77953132333
-
Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli
-
Lamoral-Theys D., Pottier L., Kerff F., Dufrasne F., Proutiere F., Wauthoz N., Neven P., Ingrassia L., Antwerpen P.V., Lefranc F., Gelbcke M., Pirotte B., Kraus J.L., Neve J., Kornienko A., Kiss R., Dubois J. Simple di- and trivanillates exhibit cytostatic properties toward cancer cells resistant to pro-apoptotic stimuli. Bioorg. Med. Chem. 2010, 18:3823-3833.
-
(2010)
Bioorg. Med. Chem.
, vol.18
, pp. 3823-3833
-
-
Lamoral-Theys, D.1
Pottier, L.2
Kerff, F.3
Dufrasne, F.4
Proutiere, F.5
Wauthoz, N.6
Neven, P.7
Ingrassia, L.8
Antwerpen, P.V.9
Lefranc, F.10
Gelbcke, M.11
Pirotte, B.12
Kraus, J.L.13
Neve, J.14
Kornienko, A.15
Kiss, R.16
Dubois, J.17
-
16
-
-
49849098245
-
Histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in clear cell sarcoma models
-
Liu S., Cheng H., Kwan W., Lubieniecka J.M., Nielsen T.O. Histone deacetylase inhibitors induce growth arrest, apoptosis, and differentiation in clear cell sarcoma models. Mol. Cancer Ther. 2008, 7:1751-1761.
-
(2008)
Mol. Cancer Ther.
, vol.7
, pp. 1751-1761
-
-
Liu, S.1
Cheng, H.2
Kwan, W.3
Lubieniecka, J.M.4
Nielsen, T.O.5
-
17
-
-
12244295468
-
In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation
-
Matsuyama A., Shimazu T., Sumida Y., Saito A., Yoshimatsu Y., Seigneurin-Berny D., Osada H., Komatsu Y., Nishino N., Khochbin S., Horinouchi S., Yoshida M. In vivo destabilization of dynamic microtubules by HDAC6-mediated deacetylation. EMBO J. 2002, 21:6820-6831.
-
(2002)
EMBO J.
, vol.21
, pp. 6820-6831
-
-
Matsuyama, A.1
Shimazu, T.2
Sumida, Y.3
Saito, A.4
Yoshimatsu, Y.5
Seigneurin-Berny, D.6
Osada, H.7
Komatsu, Y.8
Nishino, N.9
Khochbin, S.10
Horinouchi, S.11
Yoshida, M.12
-
18
-
-
51849103354
-
Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter
-
Nian H., Delage B., Pinto J.T., Dashwood R.H. Allyl mercaptan, a garlic-derived organosulfur compound, inhibits histone deacetylase and enhances Sp3 binding on the P21WAF1 promoter. Carcinogenesis 2008, 29:1816-1824.
-
(2008)
Carcinogenesis
, vol.29
, pp. 1816-1824
-
-
Nian, H.1
Delage, B.2
Pinto, J.T.3
Dashwood, R.H.4
-
19
-
-
77949724640
-
Sp proteins play a critical role in histone deacetylase inhibitor-mediated derepression of CYP46A1 gene transcription
-
Nunes M.J., Milagre I., Schnekenburger M., Gama M.J., Diederich M., Rodrigues E. Sp proteins play a critical role in histone deacetylase inhibitor-mediated derepression of CYP46A1 gene transcription. J. Neurochem. 2010, 113:418-431.
-
(2010)
J. Neurochem.
, vol.113
, pp. 418-431
-
-
Nunes, M.J.1
Milagre, I.2
Schnekenburger, M.3
Gama, M.J.4
Diederich, M.5
Rodrigues, E.6
-
20
-
-
40849151859
-
Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1
-
Petrella A., D'Acunto C.W., Rodriquez M., Festa M., Tosco A., Bruno I., Terracciano S., Taddei M., Paloma L.G., Parente L. Effects of FR235222, a novel HDAC inhibitor, in proliferation and apoptosis of human leukaemia cell lines: role of annexin A1. Eur. J. Cancer 2008, 44:740-749.
-
(2008)
Eur. J. Cancer
, vol.44
, pp. 740-749
-
-
Petrella, A.1
D'Acunto, C.W.2
Rodriquez, M.3
Festa, M.4
Tosco, A.5
Bruno, I.6
Terracciano, S.7
Taddei, M.8
Paloma, L.G.9
Parente, L.10
-
21
-
-
0032539890
-
A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases
-
Richon V.M., Emiliani S., Verdin E., Webb Y., Breslow R., Rifkind R.A., Marks P.A. A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases. Proc. Natl. Acad. Sci. USA 1998, 95:3003-3007.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 3003-3007
-
-
Richon, V.M.1
Emiliani, S.2
Verdin, E.3
Webb, Y.4
Breslow, R.5
Rifkind, R.A.6
Marks, P.A.7
-
22
-
-
84862773672
-
Epigenetics offer new horizons for colorectal cancer prevention
-
Schnekenburger M., Diederich M. Epigenetics offer new horizons for colorectal cancer prevention. Curr. Colorec. Cancer Rep. 2012, 8:66-81.
-
(2012)
Curr. Colorec. Cancer Rep.
, vol.8
, pp. 66-81
-
-
Schnekenburger, M.1
Diederich, M.2
-
23
-
-
78650710470
-
Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy
-
Schnekenburger M., Grandjenette C., Ghelfi J., Karius T., Foliguet B., Dicato M., Diederich M. Sustained exposure to the DNA demethylating agent, 2'-deoxy-5-azacytidine, leads to apoptotic cell death in chronic myeloid leukemia by promoting differentiation, senescence, and autophagy. Biochem. Pharmacol. 2011, 81:364-378.
-
(2011)
Biochem. Pharmacol.
, vol.81
, pp. 364-378
-
-
Schnekenburger, M.1
Grandjenette, C.2
Ghelfi, J.3
Karius, T.4
Foliguet, B.5
Dicato, M.6
Diederich, M.7
-
24
-
-
0242521529
-
Expression of glutathione S-transferase P1-1 in differentiating K562: role of GATA-1
-
Schnekenburger M., Morceau F., Duvoix A., Delhalle S., Trentesaux C., Dicato M., Diederich M. Expression of glutathione S-transferase P1-1 in differentiating K562: role of GATA-1. Biochem. Biophys. Res. Commun. 2003, 311:815-821.
-
(2003)
Biochem. Biophys. Res. Commun.
, vol.311
, pp. 815-821
-
-
Schnekenburger, M.1
Morceau, F.2
Duvoix, A.3
Delhalle, S.4
Trentesaux, C.5
Dicato, M.6
Diederich, M.7
-
25
-
-
4143111477
-
Increased glutathione S-transferase P1-1 expression by mRNA stabilization in hemin-induced differentiation of K562 cells
-
Schnekenburger M., Morceau F., Duvoix A., Delhalle S., Trentesaux C., Dicato M., Diederich M. Increased glutathione S-transferase P1-1 expression by mRNA stabilization in hemin-induced differentiation of K562 cells. Biochem. Pharmacol. 2004, 68:1269-1277.
-
(2004)
Biochem. Pharmacol.
, vol.68
, pp. 1269-1277
-
-
Schnekenburger, M.1
Morceau, F.2
Duvoix, A.3
Delhalle, S.4
Trentesaux, C.5
Dicato, M.6
Diederich, M.7
-
26
-
-
33644852339
-
Transcriptional and post-transcriptional regulation of glutathione S-transferase P1 expression during butyric acid-induced differentiation of K562 cells
-
Schnekenburger M., Morceau F., Henry E., Blasius R., Dicato M., Trentesaux C., Diederich M. Transcriptional and post-transcriptional regulation of glutathione S-transferase P1 expression during butyric acid-induced differentiation of K562 cells. Leuk. Res. 2006, 30:561-568.
-
(2006)
Leuk. Res.
, vol.30
, pp. 561-568
-
-
Schnekenburger, M.1
Morceau, F.2
Henry, E.3
Blasius, R.4
Dicato, M.5
Trentesaux, C.6
Diederich, M.7
-
27
-
-
84867402272
-
Chromatin-modifying agents in anti-cancer therapy
-
Seidel C., Florean C., Schnekenburger M., Dicato M., Diederich M. Chromatin-modifying agents in anti-cancer therapy. Biochimie 2012, 94:2264-2279.
-
(2012)
Biochimie
, vol.94
, pp. 2264-2279
-
-
Seidel, C.1
Florean, C.2
Schnekenburger, M.3
Dicato, M.4
Diederich, M.5
-
28
-
-
84866039617
-
Histone deacetylase modulators provided by Mother Nature
-
Seidel C., Schnekenburger M., Dicato M., Diederich M. Histone deacetylase modulators provided by Mother Nature. Gen. Nutr. 2012, 7:357-367.
-
(2012)
Gen. Nutr.
, vol.7
, pp. 357-367
-
-
Seidel, C.1
Schnekenburger, M.2
Dicato, M.3
Diederich, M.4
-
29
-
-
0034610814
-
The language of covalent histone modifications
-
Strahl B.D., Allis C.D. The language of covalent histone modifications. Nature 2000, 403:41-45.
-
(2000)
Nature
, vol.403
, pp. 41-45
-
-
Strahl, B.D.1
Allis, C.D.2
-
30
-
-
57349169361
-
YY1 protects cardiac myocytes from pathologic hypertrophy by interacting with HDAC5
-
Sucharov C.C., Dockstader K., McKinsey T.A. YY1 protects cardiac myocytes from pathologic hypertrophy by interacting with HDAC5. Mol. Biol. Cell 2008, 19:4141-4153.
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 4141-4153
-
-
Sucharov, C.C.1
Dockstader, K.2
McKinsey, T.A.3
-
32
-
-
33846964621
-
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak
-
Willis S.N., Fletcher J.I., Kaufmann T., van Delft M.F., Chen L., Czabotar P.E., Ierino H., Lee E.F., Fairlie W.D., Bouillet P., Strasser A., Kluck R.M., Adams J.M., Huang D.C. Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak. Science 2007, 315:856-859.
-
(2007)
Science
, vol.315
, pp. 856-859
-
-
Willis, S.N.1
Fletcher, J.I.2
Kaufmann, T.3
van Delft, M.F.4
Chen, L.5
Czabotar, P.E.6
Ierino, H.7
Lee, E.F.8
Fairlie, W.D.9
Bouillet, P.10
Strasser, A.11
Kluck, R.M.12
Adams, J.M.13
Huang, D.C.14
-
33
-
-
33744956666
-
Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer
-
Wilson A.J., Byun D.S., Popova N., Murray L.B., L'Italien K., Sowa Y., Arango D., Velcich A., Augenlicht L.H., Mariadason J.M. Histone deacetylase 3 (HDAC3) and other class I HDACs regulate colon cell maturation and p21 expression and are deregulated in human colon cancer. J. Biol. Chem. 2006, 281:13548-13558.
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 13548-13558
-
-
Wilson, A.J.1
Byun, D.S.2
Popova, N.3
Murray, L.B.4
L'Italien, K.5
Sowa, Y.6
Arango, D.7
Velcich, A.8
Augenlicht, L.H.9
Mariadason, J.M.10
-
34
-
-
79959261552
-
Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters
-
Xargay-Torrent S., Lopez-Guerra M., Saborit-Villarroya I., Rosich L., Campo E., Roue G., Colomer D. Vorinostat-induced apoptosis in mantle cell lymphoma is mediated by acetylation of proapoptotic BH3-only gene promoters. Clinical Cancer Research: An Official Journal of the American Association for Cancer Research 2011, 17:3956-3968.
-
(2011)
Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
, vol.17
, pp. 3956-3968
-
-
Xargay-Torrent, S.1
Lopez-Guerra, M.2
Saborit-Villarroya, I.3
Rosich, L.4
Campo, E.5
Roue, G.6
Colomer, D.7
-
35
-
-
0037416151
-
HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo
-
Zhang Y., Li N., Caron C., Matthias G., Hess D., Khochbin S., Matthias P. HDAC-6 interacts with and deacetylates tubulin and microtubules in vivo. EMBO J. 2003, 22:1168-1179.
-
(2003)
EMBO J.
, vol.22
, pp. 1168-1179
-
-
Zhang, Y.1
Li, N.2
Caron, C.3
Matthias, G.4
Hess, D.5
Khochbin, S.6
Matthias, P.7
|