Coevolutionary signals across protein lineages help capture multiple protein conformations

Proceedings of the National Academy of Sciences of the United States of America

Volumn 110, Issue 51, 2013, Pages 20533-20538

  Morcos, Faruck ^a   Jana, Biman ^a   Hwa, Terence ^b   Onuchic, José N ^a  

^a RICE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Conformational plasticity; Covariation; Molecular dynamics; Statistical inference

Indexed keywords

BINDING PROTEIN; GLUTAMATE RECEPTOR 2; MALTOSE BINDING PROTEIN; PERIPLASMIC BINDING PROTEIN; PERIPLASMIC PROTEIN;

AMINO ACID SEQUENCE; ARTICLE; COEVOLUTION; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYSTAL STRUCTURE; EVOLUTION; EXPERIMENTAL STUDY; MOLECULAR BIOLOGY; MOLECULAR DYNAMICS; PREDICTION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FAMILY; PROTEIN STRUCTURE; SEQUENCE ALIGNMENT;

EID: 84890816704     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1315625110     Document Type: Article

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