Nanostructures for Tissue Engineering/Regenerative Medicine

Biomedical Nanostructures

Volumn , Issue , 2007, Pages 375-407

  Nukavarapu, Syam P ^a   Kumbar, Sangamesh G ^a   Nair, Lakshmi S ^a   Laurencin, Cato T ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

Author keywords

Micro and nanocontact printing; Thermally induced phase separation; Tissue engineering scaffolds

Indexed keywords

EID: 84890764840     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470185834.ch15     Document Type: Chapter

References (112)

1. Data derived from American Association of Tissue Banks, Eye Bank Association of America, National Marrow Donor Program, National Kidney Foundation, Inc., and UNOS Scientific Registry; 2005.
2. Laurencin CT, Amborsio A, Borden MD, Cooper JA. Tissue engineering: orthopedic applications. Anu Rev Biomed Eng 1999;1:19-46.
3. Atala A and Lanza RP. Methods of Tissue Engineering. New York: Academic Press; 2002.
4. Kofron MD and Laurencin CT. Bone tissue engineering by gene delivery. Adv Drug Deliv Rev 2006;58:555-576.
5. Yu X, Botchwey EA, Levine EM, Pollack SR, Laurencin CT. Bioreactor-based bone tissue engineering: the influence of dynamic flow on osteoblast phenotypic expression and matrix mineralization. Proc Natl Acad Sci USA 2004;101: 11203-11208.
6. Langer R and Vacanti JP. Tissue engineering. Science 1993;260:920-926.
7. Williams DF, The Williams dictionary of Biomaterials. Liverpool UK: Liverpool University Press; 1999.
8. Williams DF. Revisiting the definition of biocompatibility. Med Device Technol 2003;14:10-13.
9. Dankers PY, Harmsen MC, Brouwer LA, van Luyn MJ, Meijer EW. A modular and supramolecular approach to bioactive scaffolds for tissue engineering. Nat Mater 2005;4:568-574.
10. Livingston T, Ducheyne P, Garino J. In vivo evaluation of a bioactive scaffold for bone tissue engineering. J Biomed Mater Res 2002;62:1-13.
11. Griffith LG. Polymeric biomaterials. Acta Mater 2000;48:263-277.
12. Hayashi T. Biodegradable polymers for biomedical uses. Prog Polym Sci 1994;19:663-702.
13. Mikos AG, Thorsen AJ, Czerwonka LA, Bao Y, Langer R. Preparation and characterization of poly(L-lactic acid) foams. Polymer 1994;35:1068-1077.
14. Mooney DJ, Baldwin DF, Suh NP, Vacanti JP, Langer R. Novel approach to fabricate porous sponges of poly(D,L-lactic-co-glycolic acid) without the use of organic solvents. Biomaterials 1996;17:1417-1422.
15. Hsu YY, et al. DL Effect of polymer foam morphology and density on kinetics of in vitro controlled release of isoniazid from compressed foam matrices. J Biomed Mater Sci 1997;35:107-116.
16. Giordano RA, et al. Mechanical properties of dense polylactic acid structures fabricated by three dimensional printing. J Biomat Sci Polym Ed 1996;8:63-75.
17. Borden M, Attawia M, Khan Y, Laurencin CT. Tissue-engineered microspherebased matrices for bone repair: design and evaluation. Biomaterials 2002;23: 551-559.
18. Ramakrishna S, et al. An Introduction to Electrospinning and Nanofibers. Singapore: World Scientific Publishing Co. Pte. Ltd; 2005.
19. Ma PX. Scaffolds for tissue fabrication. Mater Today 2004;7:30-40.
20. Stupp SI, et al. Supramolecular materials: self-organized nanostructures. Science 1997;276:384-389.
21. Khademhosseini A, Langer R, Borenstein J, Vacanti JP. Microscale technologies for tissue engineering and biology. Proc Natl Acad Sci USA 2006;103: 2480-2487.
22. Alberts B, et al. Molecular Biology of the Cell. New York: Garland Science; 2002. p 1090.
23. Murugan R and Ramakrishna S. Nano-featured scaffolds for tissue engineering: a review of spinning methodologies. Tissue Eng 2006;12:435-447.
24. Pham QP, Sharma U, Mikos AG. Electrospinning of polymeric nanofibers for tissue engineering applications: a review. Tissue Eng 2006;12:1197-1211.
25. Kumbar SG, Nair LS, Bhattacharyya S, Laurencin CT. Polymeric nanofibers as novel carriers for the delivery of therapeutic molecules. J Nanosci Nanotechnol 2006;6:2591-2607.
26. Nair LS, Bhattacharyya S, Laurencin CT. Development of novel tissue engineering scaffolds via electrospinning. Expert Opin Biol Ther 2004;4:659-668.
27. Li WJ, Laurencin CT, Caterson EJ, Tuan RS, Ko FK. Electrospun nanofibrous structure: a novel scaffold for tissue engineering. J Biomed Mater Res 2002;60: 613-621.
28. Laurencin CT and Ko FK. Hybrid nanofibril matrices for use as tissue engineering devices. US Patent 2004;6,689,166.
29. Katti DS, Robinson KW, Ko FK, Laurencin CT. Bioresorbable nanofiber-based systems for wound healing and drug delivery: optimization of fabrication parameters. J Biomed Mater Res B Appl Biomater 2004;70:286-296.
30. Nair LS, et al. Fabrication and optimization of methylphenoxy substituted polyphosphazene nanofibers for biomedical applications. Biomacromolecules 2004;5:2212-2220.
31. Bognitzki M, et al. Nanostructured fibers via electrospinning. Adv Mater 2001;13:70-72.
32. Boland ED, Wnek GE, Simpson DG, Pawlowski KJ, Bowlin GL. Tailoring tissue engineering scaffolds using electrostatic processing techniques: a study of poly(glycolic acid) electrospinning. J Macromol Sci Pure Appl Chem 2001;A38: 1231-1243.
33. Yang F, Murugan R, Wang S, Ramakrishna S. Electrospinning of nano/micro scale poly(L-lactic acid) aligned fibers and their potential in neural tissue engineering. Biomaterials 2005;26:2603-2610.
34. Li WJ, Danielson KG, Alexander PG, Tuan RS. Biological response of chondrocytes cultured in three-dimensional nanofibrous poly(epsilon-caprolactone) scaffolds. J Biomed Mater Res A 2003;67:1105-1114.
35. Geng XY, Kwon OH, Jang JH. Electrospinning of chitosan dissolved in concentrated acetic acid solution. Biomaterials 2005;26:5427-5432.
36. Almany L and Seliktar D. Biosynthetic hydrogel scaffolds made from fibrinogen and polyethylene glycol for 3D cell cultures. Biomaterials 2005;26:2467-2477.
37. Schindler M, et al. A synthetic nanofibrillar matrix to promote in vivo-like organization and morphogenesis for cell in culture. Biomaterials 2005;26: 5624-5631.
38. Matthews JA, Wnek GE, Simpson DG, Bowlin GL. Electrospinning of collagen nanofibers. Biomacromolecules 2002;3:232-238.
39. Venugopal J and Ramakrishna S. Biocompatible nanofiber matrices for the engineering of a dermal substitute for skin regeneration. Tissue Eng 2005;11:847-854.
40. Witte P, Dijkstra PJ, Berg JWA, Feijen J. Phase separation processes in polymer solutions in relation to membrane formation. J Membr Sci 1996;117:1-31.
41. Ma PX and Jennifer E. Scaffolding in Tissue Engineering. Boca Raton: CRC Press; 2006. p 125.
42. Ma PX and Zhang R. Synthetic nano-scale fibrous extracellular matrix. J Biomed Mater Res 1999;46:60-72.
43. Zhang R and Ma PX. Synthetic nano-fibrillar extracellular matrices with predesigned macroporous architectures. J Biomed Mater Res 2000;52:430-438.
44. Ma PX and Choi J. Biodegradable polymer scaffolds with well defined interconnected spherical pore network. Tissue Eng 2001;7:23-33.
45. Gross M. Travels to the Nanoworld: Miniature Machinery in Nature and Technology. New York: Perseus Books Group; 1999.
46. Zhang S, Holmes T, Lockshin L, Rich A. Spontaneous assembly of a selfcomplementary oligopeptide to form a stable macroscopic membrane. Proc Natl Acad Sci USA 1993;90:3334-3338.
47. Semino CE, Merok JR, Crane GG, Panagiotakos G, Zhang S. Functional differentiation of hepatocyte-like spheroid structures from putative liver progenitor cells in three-dimensional peptide scaffolds. Differentiation 2003;71:262-270.
48. Semino CE, et al. Entrapment of migrating hippocampal neural cells in 3D peptide nanofiber scaffold. Tissue Eng 2004;10:643-655.
49. Hartgerink JD, Beniash E, Stupp SI. Self-assembly and mineralization of peptide amphiphile nanofibers. Science 2001;294:1684-1688.
50. Murphy WL and Mooney DJ. Molecular scale bio-mimicry. Nat Biotechnol 2002;20:30-31.
51. Zhang S, et al. Self-complementary oligo peptides matrices support mammalian cell attachment. Biomaterials 1995;16:1385-1393.
52. Kisiday J, et al. Self assembling peptide hydrogel fosters chondrocyte extracellular matrix production and cell division: implications for cartilage tissue repair. Proc Natl Acad Sci USA 2002;99:9996-10001.
53. Dalby MJ, et al. Increasing fibroblast response to materials using nanotopography: morphological and genetic measurements of cell response to 13-nm-high polymer demixed islands. Exp Cell Res 2002;276:1-9.
54. Geissler M and Xia Y. Patterning: principles and some new developments. Adv Mater 2004;16:1249-1269.
55. Kane RS, Takayama S, Ostuni E, Ingber DE, Whitesides GM. Patterning proteins and cells using soft lithography. Biomaterials 1999;20:2363-2376.
56. Mrksich M, Dike LE, Tien J, Ingber DE, Whitesides GM. Using microcontact printing to pattern the attachment of mammalian cells to self-assembled monolayers of alkanethiolates on transparent films of gold and silver. Exp Cell Res 1997;235:305-313.
57. Lee CJ, et al. Microcontact printing on human tissue for retinal cell transplantation. Arch Ophthalmol 2002;120:1714-1718.
58. Li HW, Muir BVO, Fichet G, Huck WTS. Nanocontact printing: a route to sub-50-nm-scale chemical and biological patterning. Langmuir 2003;19:1963-1965.
59. Jo J, Kim KY, Lee ES, Choi BO. Nanocontact printing of nonplanar substrate by using flexible h-PDMS stamp. Proc SPIE 2005;6037:60371T.
60. Suh KY, Seong J, Khademhosseini A, Laibinis PE, Langer R. A simple soft lithographic route to fabrication of poly(ethylene glycol) microstructures for protein and cell patterning. Biomaterials 2004;25:557-563.
61. Morra M and Cassineli C. Non-fouling properties of polysaccharide coated surfaces. J Biomater Sci Polym Ed 1999;10:1107-1124.
62. Khademhosseini A, et al. Layer-by-layer deposition of hyaluronic acid and poly-Llysine for patterned cell co-cultures. Biomaterials 2004;25:3583-3592.
63. Fukuda J, et al. Micropatterned cell co-cultures using layer-by-layer deposition of extracellular matrix components. Biomaterials 2006;27:1479-1486.
64. Bearinger JP, et al. Biomolecular patterning via photocatalytic lithography. Technical Proceedings of the NSTI Nanotechnology Conference and Trade Show. Volume 1;2005. p 339-342.
65. Choi I, Kang SK, Lee J, Kim Y, Yi J. In situ observation of biomolecules patterned on a PEG-modified Si surface by scanning probe lithography. Biomaterials 2006;27:4655-4660.
66. Flemming RG, Murphy CJ, Abrams GA, Goodman SL, Nealey PF. Effects of synthetic micro and nano structured surfaces on cell behavior. Biomaterials 1999;20:573-588.
67. Karuri NW. Biological length scale topography enhances cell-substratum adhesion of human corneal epithelial cells. J Cell Sci 2004;117:3153-3164.
68. Wojciak-Stothard B, Madeja Z, Korohoda W, Curtis A, Wilkinson C. Activation of macrophase-like cells by multiple grooved substrata: topographical control of cell behaviour. Cell Biol Int 1995;19:485-490.
69. Wojciak-Stothard B, et al. Role of the cytoskeleton in the reaction of fibroblasts to multiple grooved substrata. Cell Motil Cytoskeleton 1995;31:147-158.
70. Clark P, Connolly P, Curtis A, Dow JAT, Wilkinsin C. Topographical control of cell behaviour. II. multiple grooved substrata. Development 1990;108:635-644.
71. Hoch HC, Staples RC, Whitehead B, Comeau J, Wolf ED. Signaling for growth orientation and cell differentiation by surface topography in Uromyces. Science 1997;235:1659-1662.
72. Clark P, Connolly P, Curtis A, Dow JAT, Wilkinson C. Topographical control of cell behavior. I. Simple step cues. Development 1987;99:439-448.
73. Rosdy M, Grisoni B, Clauss LC. Proliferation of normal human keratinocytes on silicone substrates. Biomaterials 1991;12:511-517.
74. Spaargaren M and Bos JL. Rab5 induces Rac dependant lamellipodia formation and cell migration. Mol Biol Cell 1999;10:3239-3250.
75. Liu X and Ma PX. Polymer scaffolds for bone tissue engineering. Ann Biomedical Eng 2004;32:477-486.
76. Christenson EM, et al. Nanobiomaterial applications in orthopedics. J Orthop Res 2007;25(1):11-22.
77. Yoshimoto H, Shin YM, Terai H, Vacanti JP. A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. Biomaterials 2003;24:2077-2082.
78. Shin M, Yoshimoto H, Vacanti JP. In vivo bone tissue engineering using mesenchymal stem cells on a novel electrospun nanofibrous scaffolds. Tissue Eng 2004;10:33-41.
79. Pelled G, et al. Structural and nanoindentation studies of stem cell-based tissueengineered bone. J Biomech 2007;40:399-411.
80. Hosseinkhani H, Hosseinkhani M, Tian F, Kobayashi H, Tabata Y. Osteogenic differentiation of mesenchymal stem cells in self-assembled peptide-amphiphile nanofibers. Biomaterials 2006;27:4079-4086.
81. Hosseinkhani H, Hosseinkhani M, Tian F, Kobayashi H, Tabata Y. Ectopic bone formation in collagen sponge self-assembled peptide-amphiphile nanofibers hybrid scaffold in a perfusion culture bioreactor. Biomaterials 2006;27:5089-5098.
82. Wei G and Ma PX. Structure and properties of nano-hydroxyapatite/polymer composite scaffolds for tissue engineering. Biomaterials 2004;25:4749-4757.
83. Li WJ, et al. A three-dimensional nanofibrous scaffold for cartilage tissue engineering using human mesenchymal stem cells. Biomaterials 2005;26:599-609
84. Muraglia A, et al. Formation of a chondroosseous rudiment in micromass cultures of human bone-marrow stromal cells. J Cell Sci 2003;116:2949-2955.
85. Niklason LE, et al. Functional arteries grown in vitro. Science 1999;284:489-493.
86. Watanabe M, et al. Tissue-engineered vascular autograft: inferior vena cava replacement in a dog model. Tissue Eng 2002;7:429-439.
87. Mo XM, Xu CY, Kotaki M, Ramakrishna S. Electrospun P(LLA-CL) nanofiber: a biomimetic extracellular matrix for smooth muscle cell and endothelial cell proliferation. Biomaterials 2004;25:1883-1890.
88. Xu CY, Inai R, Kotaki M, Ramakrishna S. Aligned biodegradable nanofibrous structure: a potential scaffold for blood vessel engineering. Biomaterials 2004;25: 877-886.
89. Ma Z, He W, Yong T, Ramakrishna S. Grafting of gelatin on electrospun poly(caprolactone) nanofibers to improve endothelial cell spreading and proliferation and to control cell orientation. Tissue Eng 2005;11:1149-1158.
90. He W, Yong T, Teo WE, Ma Z, Ramakrishna S. Fabrication and endothelialization of collagen-blended biodegradable polymer nanofibers: potential vascular graft for blood vessel tissue engineering. Tissue Eng 2005;11:1574-1588.
91. Lee KW. Sustained release of vascular endothelial growth factor from calciuminduced alginate hydrogels reinforced by heparin and chitosan. Transplant Proc 2004;36:2464-2465.
92. Ferrara N, Gerber HP, LeCouter J. The biology of VEGF and its receptors. Nat Med 2003;9:669-676.
93. Schlessinger J, et al. Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization. Mol Cell 2000;6:743-750.
94. Rajangam K, et al. Heparin binding nanostructures to promote growth of blood vessels. Nano Lett 2006;6:2086-2090.
95. Fawcett JW and Asher RA. The glial scar and central nervous system repair. Brain Res Bull 1999;49:377-391.
96. Holmes TC, et al. Extensive neurite outgrowth and active synapse formation on self-assembling peptide scaffolds. Proc Natl Acad Sci USA 2000;97:6728-6733.
97. Ellis-Behnke RG, et al. Nano neuro knitting: peptide nanofiber scaffold for brain repair and axon regeneration with functional return of vision. Proc Natl Acad Sci USA 2006;103:5054-5059.
98. Chen ZJ, Ughrin Y, Levine JM. Inhibition of axon growth by oligodendrocyte precursor cells. Mol Cell Neurosci 2002;20:125-139.
99. Silva GA, et al. Selective differentiation of neural progenitor cells by high-epitope density nanofibers. Science 2004;303:1352-1355.
100. Koh GY, Soonpaa MH, Klug MG, Field LJ. Strategies for myocardial repair. J Interv Cardiol 1995;8:387-393.
101. Malosky S and Kolansky DM. Gene therapy for ischemic heart disease. Curr Opin Cardiol 1996;11:361-368.
102. Hassink RJ, Dowell JD, Riviere BA, Doevendans PA, Field LJ. Stem cell therapy for ischemic heart disease. Trends Mol Med 2003;9:436-441.
103. Leor J and Cohen S. Myocardial tissue engineering: creating a muscle patch for a wounded heart. Ann N Y Acad Sci 2004;1015:312-319.
104. Akhyari P, et al. Mechanical stretch regimen enhances the formation of bioengineered autologous cardiac muscle grafts. Circulation 2002;106:I137-I142.
105. Kofidis T, et al. In vitro engineering of heart muscle: artificial myocardial tissue. J Thorac Cardiovasc Surg 2002;124:63-69.
106. Zong X, et al. Electrospun fine-textured scaffolds for heart tissue constructs. Biomaterials 2005;26:5330-5338.
107. Shin M, Ishii O, Sueda T, Vacanti JP. Contractile cardiac grafts using a novel nanofibrous mesh. Biomaterials 2004;25:3717-3723.
108. Venugopal J and Ramakrishna S. Biocompatible nanofiber matrices for the engineering of a dermal substitute for skin regeneration. Tissue Eng 2005;11: 847-854.
109. Pattison MA, Wurster S, Webster TJ, Haberstroh KM. Three-dimensional, nanostructured PLGA scaffolds for bladder tissue replacement applications. Biomaterials 2005;26:2491-2500.
110. Berthiaume F, Moghe PV, Toner M, Yarmush ML. Effect of extracellular matrix topology on cell structure, function, and physiological responsiveness: hepatocytes cultured in a sandwich configuration. FASEB J 1996;10:1471-1484.
111. Langer R. Tissue engineering: status and challenges. E-biomed: J Reg Med 2000;1: 5-6.
112. Langer R, et al. Tissue Engineering: biomedical applications. Tissue Eng 1995;1: 151-162.