Inhibition of axon growth by oligodendrocyte precursor cells

Molecular and Cellular Neuroscience

Volumn 20, Issue 1, 2002, Pages 125-139

  Chen, Zhi Jiang ^a   Ughrin, Yvonne ^a   Levine, Joel M ^a  

^a STONY BROOK UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEOCHONDROITIN SULFATE;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL SURFACE; CONTROLLED STUDY; GROWTH INHIBITION; INHIBITION KINETICS; MEMBRANE PERMEABILITY; NERVE FIBER GROWTH; NERVE REGENERATION; NONHUMAN; OLIGODENDROGLIA; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SENSORY NERVE CELL; STEM CELL; SURFACE PROPERTY;

ANIMALIA; GILA;

EID: 0036286136     PISSN: 10447431     EISSN: None     Source Type: Journal    
DOI: 10.1006/mcne.2002.1102     Document Type: Article

References (82)

1. Versican is upregulated in CNS injury and is a product of O-2A lineage cells
2. Neurocan is upregulated in injured brain and in cytokine-treated astrocytes
3. Expansion of rat oligodendrocyte progenitors into proliferative "Oligospheres" that retain differentiation potential
4. Astrocytes from adult rat optic nerves are nonpermissive for regenerating retinal ganglion cell axons
5. NI-35/250/Nogo-A: A neurite growth inhibitor restricting structural plasticity and regeneration of nerve fibers in the adult vertebrate CNS
6. Lack of evidence that the myelin-associated glycoprotein is a major inhibitor of axonal regeneration in the CNS
7. Behavior of fish retinal growth cones encountering chick caudal tectal membranes: A time-lapse study on growth cone collapse
8. Characterization of a neurite outgrowth inhibitor expressed after CNS injury
9. A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury study
10. Acute and long-lasting changes in extracellular-matrix chondroitin-sulphate proteoglycans induced by injection of chondroitinase ABC in the adult rat brain
11. Prior exposure to neurotrophins blocks inhibition of axonal regeneration by MAG and myelin via a cAMP-dependent mechanism
12. Three froms of RPTP-β are differentially expressed during gliogenesis in the developing rat brain and during glial cell differentiation in culture
13. Actin filament bundles are required for microtubule reorientation during growth cone turning to avoid an inhibitory guidance cue
14. Nogo-A is a myelin-associated neurite outgrowth inhibitor and an antigen for monoclonal antibody IN-1
15. Chondroitin sulfate E promoters neurite outgrowth of rat embryonic day 18 hippocampal neurons
16. The effects of methylprednisolone and ganglioside Gm1 on acute spinal cord injury in rats
17. Regeneration of adult axons in white matter tracts of the central nervous system
18. Robust regeneration of adult sensory axons in degenerating white matter of the adult rat spinal cord
19. NG2-expressing cells in the central nervous system: Are they oligodendroglial progenitors?
20. Inhibition of neurite outgrowth by the NG2 chondroitin sulfate proteoglycan
21. Differential effects of glycosaminoglycans on neurite growth on laminin and L1 substrate
22. Identification of a neuronal cell surface receptor for a growth inhibitory chondroitin sulfate proteoglycan (NG2)
23. In vitro guidance of retinal cell axons by RAGS, a 25kD tectal protein related to ligands of eph receptor tyrosine kinases
24. The glial scar and central nervous system repair
25. Comparing astrocytic cell lines that are inhibitory or permissive for axon growth: The major axon-inhibitory proteoglycan is NG2
26. Neurite outgrowth patterns in cerebellar microexplant cultures are affected by antibodies to the cell surface glycoprotein L1
27. Cytokine-induced changes in the ability of astrocytes to support migration of oligodendrocyte precursors and axon growth
28. Repulsive factors and axon regeneration in CNS
29. The neuronal chondroitin sulfate proteoglycan neurocan binds to the neural cell adhesion molecules Ng-CAM/L1/NILE and N-CAM, and inhibits neuronal adhesion and neurite outgrowth
30. Extracellular matrix of cultured glial cells: Selective expression of chondroitin 4-sulfate by type-2 astrocytes and their progenitors
31. DSD-1-proteoglycan is the mouse homolog of phosphacan and displays opposing effects on neurite outgrowth dependent on neuronal lineage
32. Identification of the Nogo inhibitor of axon regeneration as a reticulon protein
33. Neuronal regulation of astroglial morphology and proliferation in vitro
34. Fibronectin and laminin elicit differential behaviors from SH-SY5Y growth cones contacting inhibitory chondroitin sulfate proteoglycans
35. Response of the oligodendrocyte progenitor cell population (defined by NG2 labeling) to demyelination of the adult spinal cord
36. Increased expression of the NG2 chondroitin-sulfate proteoglycan after brain injury
37. Light and electron microscopic localization of a cell surface antigen (NG2) in the rat: Association with smooth protoplasmic astrocytes
38. Reactions of oligodendrocyte precursor cells to alpha herpes virus infection of the central nervous system
39. The NG2 chondroitin sulfate proteoglycan: A multifunctional proteoglycan associated with immature cells
40. Activation and proliferation of endogenous oligodendrocyte precursor cells during ethidium bromide-induced demyelination
41. The oligodendrocyte precursor cell in health and disease
42. Plasticity of developing cerebellar cells in vitro studies with antibodies against the NG2 antigen
43. Development and differentiation of glial precursor cells in the rat cerebellum
44. CG4, a new bipotential glial cell line from rat brain, is capable of differentiating in vitro either mature oligodendrocytes or type-2 astrocytes
45. Phosphacan, a chondroitin sulfate proteoglycan of brain that interacts with neurons and neural cell-adhesion molecules, is an extracellular variant of a receptor-type protein tyrosine phosphatase
46. Preparation of separate astroglial and oligodendrocyte cultures from rat cerebral tissue
47. Injury-induced proteoglycans inhibit the potential for laminin-mediate axon growth on astrocytic scars
48. The chondroitin sulfate proteoglycans neurocan and phosphacan are expressed by reactive astrocytes in the chronic CNS glial scar
49. Reduction of neurite outgrowth in a model of glial scarring following CNS injury is correlated with expression of inhibitory molecules on reactive astrocytes
50. Identification of myelin-associated glycoprotein as a major myelin-derived inhibitor of neurite growth
51. Proliferation of NG2-positive cells and altered oligodendrocyte numbers in the contused rat spinal cord
52. Interaction of the chondroitin sulfate proteoglycan phosphacan, the extracellular domain of a receptor-type tyrosine phosphatase, with neurons, glia and neural adhesion molecules
53. Regeneration of CNS axons back to their original target following treatment of adult rat brain with chondroitinase ABC
54. Robust regeneration of CNS axons through a track depleted of CNS gila
55. A novel role for myelin-associated glycoproteins as an inhibitor of axonal regeneration
56. Topographically specific effects of elf-1 on retinal axon guidance in vitro and retinal mapping in vivo
57. Regeneration of dorsal column fibers into and beyond the lesion site following adult spinal cord injury
58. Bovine CNS myelin contains neurite growth-inhibitory activity associated with chondroitin sulfate proteoglycans
59. NG2+ glial cells: A novel cell population in the adult brain
60. The primary structure of NG2, a novel membrane-spanning proteoglycan
61. Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brain
62. Normal and reactive NG2+ glial cells are distinct from resting and activated microglia
63. PSA-NCAM distinguishes reactive astrocytes in 6-OHDA-lesioned substantia nigra from those in the striatal terminal fields
64. A light and electron microscopic study of NG2 chondroitin sulfate proteoglycan-positive oligodendrocyte precursor cells in the normal and kainate-lesioned rat hippocampus
65. Neutralizing antibodies against neurite growth inhibitor NI-35/250 do not promote regeneration of sensory axons in the adult rat spinal cord
66. Peripheral nerve injury fails to induce growth of lesioned ascending dorsal column axons into spinal cord scar tissue expressing the axon repellent Semaphorin3A
67. Expression of the gene encoding the chemorepellent Semaphorin III is induced in the fibroblast component of neural scar tissue formed following injuries of adult but not neonatal CNS
68. Putative inhibitory extracellular matrix molecules at the dorsal root entry zone of the spinal cord during development and after root and sciatic nerve lesions
69. Inhibitory proteoglycan immunoreactivity is higher at the caudal than the rostral schwann cell graft-transected spinal cord interface
70. Glial inhibition of nerve regeneration in the mature mammalian CNS
71. The astrocytic scar as an impediment to regeneration in the central nervous system
72. Brain derived versican v2 is a potent inhibitor of axon growth
73. Axonal regeneration in the rat spinal cord produced by an antibody against myelin-associated neurite growth inhibitors
74. Myelin-associated glycoprotein in myelin and expressed by schwann cells inhibits axonal regeneration and branching
75. Sulfated proteoglycans in astroglial barriers inhibit neurite outgrowth in vitro
76. Clearance of myelin constituents and axonal sprouting in the transected postcommissural fornix of the adult rat
77. Maturation-dependent upregulation of growth-promoting molecules in developing cortical plate controls thalamic and cortical neurite growth
78. Multiple globular domains of the NG2 proteoglycan core protein mediate neurite growth inhibition
79. Influence of glycosaminoglycans on neurite morphology and outgrowth patterns in vitro
80. Recognition of position-specific properties of tectal cell membranes by retinal axons in vitro
81. Eph fami]y transmembrane ligands can mediate repulsive guidance of trunk neural crest migration and motor axon outgrowth
82. Antisera specific for cell lines with mixed neuronal and glial properties