-
1
-
-
33847199801
-
Emerging roles of nuclear protein phosphatases
-
Moorhead, G. B., Trinkle-Mulcahy, L., and, Ulke-Lemee, A., (2007) Emerging roles of nuclear protein phosphatases. Nat. Rev. Mol. Cell Biol. 8, 234-244.
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 234-244
-
-
Moorhead, G.B.1
Trinkle-Mulcahy, L.2
Ulke-Lemee, A.3
-
3
-
-
77952552642
-
The Akt-SREBP nexus: Cell signaling meets lipid metabolism
-
Krycer, J. R., Sharpe, L. J., Luu, W., and, Brown, A. J., (2010) The Akt-SREBP nexus: cell signaling meets lipid metabolism. Trends Endocrinol. Metab. 21, 268-276.
-
(2010)
Trends Endocrinol. Metab.
, vol.21
, pp. 268-276
-
-
Krycer, J.R.1
Sharpe, L.J.2
Luu, W.3
Brown, A.J.4
-
4
-
-
79960624651
-
The complex interplay between cholesterol and prostate malignancy
-
Solomon, K. R., and, Freeman, M. R., (2011) The complex interplay between cholesterol and prostate malignancy. Urol. Clin. N Am. 38, 243-259.
-
(2011)
Urol. Clin. N Am.
, vol.38
, pp. 243-259
-
-
Solomon, K.R.1
Freeman, M.R.2
-
5
-
-
84873716248
-
Cholesterol accumulation in prostate cancer: A classic observation from a modern perspective
-
Krycer, J. R., and, Brown, A. J., (2013) Cholesterol accumulation in prostate cancer: a classic observation from a modern perspective. Biochim. Biophys. Acta 1835, 219-229.
-
(2013)
Biochim. Biophys. Acta
, vol.1835
, pp. 219-229
-
-
Krycer, J.R.1
Brown, A.J.2
-
6
-
-
33744732467
-
Involvement of akt in ER-to-Golgi transport of SCAP/SREBP: A link between a key cell proliferative pathway and membrane synthesis
-
DOI 10.1091/mbc.E05-11-1094
-
Du, X., Kristiana, I., Wong, J., and, Brown, A. J., (2006) Involvement of Akt in ER-to-Golgi transport of SCAP/SREBP: a link between a key cell proliferative pathway and membrane synthesis. Mol. Biol. Cell 17, 2735-2745. (Pubitemid 43825509)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.6
, pp. 2735-2745
-
-
Du, X.1
Kristiana, I.2
Wong, J.3
Brown, A.J.4
-
7
-
-
84855808743
-
Akt acutely activates the cholesterogenic transcription factor SREBP-2
-
Luu, W., Sharpe, L. J., Stevenson, J., and, Brown, A. J., (2012) Akt acutely activates the cholesterogenic transcription factor SREBP-2. Biochim. Biophys. Acta 1823, 458-464.
-
(2012)
Biochim. Biophys. Acta
, vol.1823
, pp. 458-464
-
-
Luu, W.1
Sharpe, L.J.2
Stevenson, J.3
Brown, A.J.4
-
8
-
-
48949115069
-
Rapamycin down-regulates LDL-receptor expression independently of SREBP-2. Biochem
-
Sharpe, L. J., and, Brown, A. J., (2008) Rapamycin down-regulates LDL-receptor expression independently of SREBP-2. Biochem. Biophys. Res. Commun. 373, 670-674.
-
(2008)
Biophys. Res. Commun.
, vol.373
, pp. 670-674
-
-
Sharpe, L.J.1
Brown, A.J.2
-
9
-
-
50049116472
-
SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth
-
Porstmann, T., Santos, C. R., Griffiths, B., Cully, M., Wu, M., et al. (2008) SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth. Cell Metab. 8, 224-236.
-
(2008)
Cell Metab.
, vol.8
, pp. 224-236
-
-
Porstmann, T.1
Santos, C.R.2
Griffiths, B.3
Cully, M.4
Wu, M.5
-
10
-
-
23844530704
-
Fbw7
-
DOI 10.1016/j.cmet.2005.04.010, PII S155041310500118X
-
Sundqvist, A., Bengoechea-Alonso, M. T., Ye, X., Lukiyanchuk, V., Jin, J., et al. (2005) Control of lipid metabolism by phosphorylation-dependent degradation of the SREBP family of transcription factors by SCF(Fbw7). Cell Metab. 1, 379-391. (Pubitemid 43960622)
-
(2005)
Cell Metabolism
, vol.1
, Issue.6
, pp. 379-391
-
-
Sundqvist, A.1
Bengoechea-Alonso, M.T.2
Ye, X.3
Lukiyanchuk, V.4
Jin, J.5
Harper, J.W.6
Ericsson, J.7
-
11
-
-
65549140251
-
A phosphorylation cascade controls the degradation of active SREBP1
-
Bengoechea-Alonso, M. T., and, Ericsson, J., (2009) A phosphorylation cascade controls the degradation of active SREBP1. J. Biol. Chem. 284, 5885-5895.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 5885-5895
-
-
Bengoechea-Alonso, M.T.1
Ericsson, J.2
-
12
-
-
2542418816
-
Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding protein-2 at serine residues 432 and 455 in vivo
-
DOI 10.1074/jbc.M401198200
-
Kotzka, J., Lehr, S., Roth, G., Avci, H., Knebel, B., et al. (2004) Insulin-activated Erk-mitogen-activated protein kinases phosphorylate sterol regulatory element-binding Protein-2 at serine residues 432 and 455 in vivo. J. Biol. Chem. 279, 22404-22411. (Pubitemid 38679438)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.21
, pp. 22404-22411
-
-
Kotzka, J.1
Lehr, S.2
Roth, G.3
Avci, H.4
Knebel, B.5
Muller-Wieland, D.6
-
13
-
-
47249140920
-
Growth factor-induced phosphorylation of sterol regulatory element-binding proteins inhibits sumoylation, thereby stimulating the expression of their target genes, low density lipoprotein uptake, and lipid synthesis
-
Arito, M., Horiba, T., Hachimura, S., Inoue, J., and, Sato, R., (2008) Growth factor-induced phosphorylation of sterol regulatory element-binding proteins inhibits sumoylation, thereby stimulating the expression of their target genes, low density lipoprotein uptake, and lipid synthesis. J. Biol. Chem. 283, 15224-15231.
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 15224-15231
-
-
Arito, M.1
Horiba, T.2
Hachimura, S.3
Inoue, J.4
Sato, R.5
-
14
-
-
33747867030
-
Phosphorylation of the liver X receptors
-
DOI 10.1016/j.febslet.2006.07.074, PII S0014579306009306
-
Chen, M., Bradley, M. N., Beaven, S. W., and, Tontonoz, P., (2006) Phosphorylation of the liver X receptors. FEBS Lett. 580, 4835-4841. (Pubitemid 44286840)
-
(2006)
FEBS Letters
, vol.580
, Issue.20
, pp. 4835-4841
-
-
Chen, M.1
Bradley, M.N.2
Beaven, S.W.3
Tontonoz, P.4
-
15
-
-
42149194355
-
Phosphorylation of liver X receptor α selectively regulates target gene expression in macrophages
-
DOI 10.1128/MCB.01575-07
-
Torra, I. P., Ismaili, N., Feig, J. E., Xu, C. F., Cavasotto, C., et al. (2008) Phosphorylation of liver X receptor alpha selectively regulates target gene expression in macrophages. Mol. Cell. Biol. 28, 2626-2636. (Pubitemid 351542363)
-
(2008)
Molecular and Cellular Biology
, vol.28
, Issue.8
, pp. 2626-2636
-
-
Torra, I.P.1
Ismaili, N.2
Feig, J.E.3
Xu, C.-F.4
Cavasotto, C.5
Pancratov, R.6
Rogatsky, I.7
Neubert, T.A.8
Fisher, E.A.9
Garabedian, M.J.10
-
16
-
-
79957576579
-
Control of nuclear receptor activities in metabolism by post-translational modifications
-
Berrabah, W., Aumercier, P., Lefebvre, P., and, Staels, B., (2011) Control of nuclear receptor activities in metabolism by post-translational modifications. FEBS Lett. 585, 1640-1650.
-
(2011)
FEBS Lett.
, vol.585
, pp. 1640-1650
-
-
Berrabah, W.1
Aumercier, P.2
Lefebvre, P.3
Staels, B.4
-
17
-
-
84857047339
-
PhosphoSitePlus: A comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse
-
Hornbeck, P. V., Kornhauser, J. M., Tkachev, S., Zhang, B., Skrzypek, E., et al. (2012) PhosphoSitePlus: a comprehensive resource for investigating the structure and function of experimentally determined post-translational modifications in man and mouse. Nucleic Acids Res. 40, D261-D270.
-
(2012)
Nucleic Acids Res.
, vol.40
-
-
Hornbeck, P.V.1
Kornhauser, J.M.2
Tkachev, S.3
Zhang, B.4
Skrzypek, E.5
-
18
-
-
0015864346
-
Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol
-
Beg, Z. H., Allmann, D. W., and, Gibson, D. M., (1973) Modulation of 3-hydroxy-3-methylglutaryl coenzyme A reductase activity with cAMP and wth protein fractions of rat liver cytosol. Biochem. Biophys. Res. Commun. 54, 1362-1369.
-
(1973)
Biochem. Biophys. Res. Commun.
, vol.54
, pp. 1362-1369
-
-
Beg, Z.H.1
Allmann, D.W.2
Gibson, D.M.3
-
19
-
-
84857687439
-
AMPK functions as an adenylate charge-regulated protein kinase
-
Oakhill, J. S., Scott, J. W., and, Kemp, B. E., (2012) AMPK functions as an adenylate charge-regulated protein kinase. Trends Endocrinol. Metab. 23, 125-132.
-
(2012)
Trends Endocrinol. Metab.
, vol.23
, pp. 125-132
-
-
Oakhill, J.S.1
Scott, J.W.2
Kemp, B.E.3
-
20
-
-
0025310576
-
Regulation of HMG-CoA reductase: Identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liver
-
Clarke, P. R., and, Hardie, D. G., (1990) Regulation of HMG-CoA reductase: identification of the site phosphorylated by the AMP-activated protein kinase in vitro and in intact rat liver. EMBO J. 9, 2439-2446.
-
(1990)
EMBO J.
, vol.9
, pp. 2439-2446
-
-
Clarke, P.R.1
Hardie, D.G.2
-
21
-
-
79961118496
-
Regulation of HMG-CoA reductase in mammals and yeast
-
Burg, J. S., and, Espenshade, P. J,. (2011) Regulation of HMG-CoA reductase in mammals and yeast. Prog. Lipid Res. 50, 403-410.
-
(2011)
Prog. Lipid Res.
, vol.50
, pp. 403-410
-
-
Burg, J.S.1
Espenshade, P.J.2
-
22
-
-
0027428833
-
Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion
-
DOI 10.1073/pnas.90.20.9261
-
Sato, R., Goldstein, J. L., and, Brown, M. S., (1993) Replacement of serine-871 of hamster 3-hydroxy-3-methylglutaryl-CoA reductase prevents phosphorylation by AMP-activated kinase and blocks inhibition of sterol synthesis induced by ATP depletion. Proc. Natl. Acad. Sci. USA 90, 9261-9265. (Pubitemid 23315763)
-
(1993)
Proceedings of the National Academy of Sciences of the United States of America
, vol.90
, Issue.20
, pp. 9261-9265
-
-
Sato, R.1
Goldstein, J.L.2
Brown, M.S.3
-
23
-
-
44849131929
-
Feedback regulation of cholesterol synthesis: Sterol-accelerated ubiquitination and degradation of HMG CoA reductase
-
DeBose-Boyd, R. A., (2008) Feedback regulation of cholesterol synthesis: sterol-accelerated ubiquitination and degradation of HMG CoA reductase. Cell Res. 18, 609-621.
-
(2008)
Cell Res.
, vol.18
, pp. 609-621
-
-
Debose-Boyd, R.A.1
-
24
-
-
84869021501
-
AMP-activated protein kinase: An emerging drug target to regulate imbalances in lipid and carbohydrate metabolism to treat cardio-metabolic diseases
-
Srivastava, R. A., Pinkosky, S. L., Filippov, S., Hanselman, J. C., Cramer, C. T., et al. (2012) AMP-activated protein kinase: an emerging drug target to regulate imbalances in lipid and carbohydrate metabolism to treat cardio-metabolic diseases. J. Lipid Res. 53, 2490-2514.
-
(2012)
J. Lipid Res.
, vol.53
, pp. 2490-2514
-
-
Srivastava, R.A.1
Pinkosky, S.L.2
Filippov, S.3
Hanselman, J.C.4
Cramer, C.T.5
-
25
-
-
84860469242
-
Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease
-
Min, H. K., Kapoor, A., Fuchs, M., Mirshahi, F., Zhou, H., et al. (2012) Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease. Cell Metab. 15, 665-674.
-
(2012)
Cell Metab.
, vol.15
, pp. 665-674
-
-
Min, H.K.1
Kapoor, A.2
Fuchs, M.3
Mirshahi, F.4
Zhou, H.5
-
26
-
-
0023149125
-
Phosphorylation of serine 833 in cytoplasmic domain of low density lipoprotein receptor by a high molecular weight enzyme resembling casein kinase II
-
Kishimoto, A., Brown, M. S., Slaughter, C. A., and, Goldstein, J. L., (1987) Phosphorylation of serine 833 in cytoplasmic domain of low density lipoprotein receptor by a high molecular weight enzyme resembling casein kinase II. J. Biol. Chem. 262, 1344-1351. (Pubitemid 17028456)
-
(1987)
Journal of Biological Chemistry
, vol.262
, Issue.3
, pp. 1344-1351
-
-
Kishimoto, A.1
Brown, M.S.2
Slaughter, C.A.3
Goldstein, J.L.4
-
27
-
-
79953214429
-
Janus kinase activation by cytokine oncostatin M decreases PCSK9 expression in liver cells
-
Cao, A., Wu, M., Li, H., and, Liu, J., (2011) Janus kinase activation by cytokine oncostatin M decreases PCSK9 expression in liver cells. J. Lipid Res. 52, 518-530.
-
(2011)
J. Lipid Res.
, vol.52
, pp. 518-530
-
-
Cao, A.1
Wu, M.2
Li, H.3
Liu, J.4
-
28
-
-
44949241428
-
PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans
-
DOI 10.1111/j.1742-4658.2008.06495.x
-
Dewpura, T., Raymond, A., Hamelin, J., Seidah, N. G., Mbikay, M., et al. (2008) PCSK9 is phosphorylated by a Golgi casein kinase-like kinase ex vivo and circulates as a phosphoprotein in humans. FEBS J. 275, 3480-3493. (Pubitemid 351813558)
-
(2008)
FEBS Journal
, vol.275
, Issue.13
, pp. 3480-3493
-
-
Dewpura, T.1
Raymond, A.2
Hamelin, J.3
Seidah, N.G.4
Mbikay, M.5
Chretien, M.6
Mayne, J.7
-
29
-
-
84870048419
-
High-density lipoprotein function, dysfunction, and reverse cholesterol transport
-
Fisher, E. A., Feig, J. E., Hewing, B., Hazen, S. L., and, Smith, J. D., (2012) High-density lipoprotein function, dysfunction, and reverse cholesterol transport. Arterioscler. Thromb. Vasc. Biol. 32, 2813-2820.
-
(2012)
Arterioscler. Thromb. Vasc. Biol.
, vol.32
, pp. 2813-2820
-
-
Fisher, E.A.1
Feig, J.E.2
Hewing, B.3
Hazen, S.L.4
Smith, J.D.5
-
30
-
-
84857636796
-
Regulation of ABCA1 functions by signaling pathways
-
Liu, Y., and, Tang, C., (2012) Regulation of ABCA1 functions by signaling pathways. Biochim. Biophys. Acta 1821, 522-529.
-
(2012)
Biochim. Biophys. Acta
, vol.1821
, pp. 522-529
-
-
Liu, Y.1
Tang, C.2
-
31
-
-
84856411164
-
Signal transduction pathways provide opportunities to enhance HDL and apoAI-dependent reverse cholesterol transport
-
Mulay, V., Wood, P., Rentero, C., Enrich, C., and, Grewal, T., (2012) Signal transduction pathways provide opportunities to enhance HDL and apoAI-dependent reverse cholesterol transport. Curr. Pharm. Biotechnol. 13, 352-364.
-
(2012)
Curr. Pharm. Biotechnol.
, vol.13
, pp. 352-364
-
-
Mulay, V.1
Wood, P.2
Rentero, C.3
Enrich, C.4
Grewal, T.5
-
32
-
-
0029804198
-
Cyclic AMP induces apolipoprotein E binding activity and promotes cholesterol efflux from a macrophage cell line to apolipoprotein acceptors
-
DOI 10.1074/jbc.271.48.30647
-
Smith, J. D., Miyata, M., Ginsberg, M., Grigaux, C., Shmookler, E., et al. (1996) Cyclic AMP induces apolipoprotein E binding activity and promotes cholesterol efflux from a macrophage cell line to apolipoprotein acceptors. J. Biol. Chem. 271, 30647-30655. (Pubitemid 26404080)
-
(1996)
Journal of Biological Chemistry
, vol.271
, Issue.48
, pp. 30647-30655
-
-
Smith, J.D.1
Miyata, M.2
Ginsberg, M.3
Grigaux, C.4
Shmookler, E.5
Plump, A.S.6
-
33
-
-
0034666311
-
The correlation of ATP-binding cassette 1 mRNA levels with cholesterol efflux from various cell lines
-
Bortnick, A. E., Rothblat, G. H., Stoudt, G., Hoppe, K. L., Royer, L. J., et al. (2000) The correlation of ATP-binding cassette 1 mRNA levels with cholesterol efflux from various cell lines. J. Biol. Chem. 275, 28634-28640.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 28634-28640
-
-
Bortnick, A.E.1
Rothblat, G.H.2
Stoudt, G.3
Hoppe, K.L.4
Royer, L.J.5
-
34
-
-
0034602387
-
ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages
-
Oram, J. F., Lawn, R. M., Garvin, M. R., and, Wade, D. P., (2000) ABCA1 is the cAMP-inducible apolipoprotein receptor that mediates cholesterol secretion from macrophages. J. Biol. Chem. 275, 34508-34511.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 34508-34511
-
-
Oram, J.F.1
Lawn, R.M.2
Garvin, M.R.3
Wade, D.P.4
-
35
-
-
24344446896
-
Lipid efflux in human and mouse macrophagic cells: Evidence for differential regulation of phospholipid and cholesterol efflux
-
DOI 10.1194/jlr.M400482-JLR200
-
Kiss, R. S., Maric, J., and, Marcel, Y. L., (2005) Lipid efflux in human and mouse macrophagic cells: evidence for differential regulation of phospholipid and cholesterol efflux. J. Lipid Res. 46, 1877-1887. (Pubitemid 41248484)
-
(2005)
Journal of Lipid Research
, vol.46
, Issue.9
, pp. 1877-1887
-
-
Kiss, R.S.1
Maric, J.2
Marcel, Y.L.3
-
36
-
-
0036906470
-
CAMP induces ABCA1 phosphorylation activity and promotes cholesterol efflux from fibroblasts
-
DOI 10.1194/jlr.M200235-JLR200
-
Haidar, B., Denis, M., Krimbou, L., Marcil, M., and, Genest, J., Jr., (2002) cAMP induces ABCA1 phosphorylation activity and promotes cholesterol efflux from fibroblasts. J. Lipid Res. 43, 2087-2094. (Pubitemid 35471076)
-
(2002)
Journal of Lipid Research
, vol.43
, Issue.12
, pp. 2087-2094
-
-
Haidar, B.1
Denis, M.2
Krimbou, L.3
Marcil, M.4
Genest Jr., J.5
-
37
-
-
18644378203
-
Protein kinase A site-specific phosphorylation regulates ATP-binding cassette A1 (ABCA1)-mediated phospholipid efflux
-
DOI 10.1074/jbc.M204923200
-
See, R. H., Caday-Malcolm, R. A., Singaraja, R. R., Zhou, S., Silverston, A., et al. (2002) Protein kinase A site-specific phosphorylation regulates ATP-binding cassette A1 (ABCA1)-mediated phospholipid efflux. J. Biol. Chem. 277, 41835-41842. (Pubitemid 35257494)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.44
, pp. 41835-41842
-
-
See, R.H.1
Caday-Malcolm, R.A.2
Singaraja, R.R.3
Zhou, S.4
Silverston, A.5
Huber, M.T.6
Moran, J.7
James, E.R.8
Janoo, R.9
Savill, J.M.10
Rigot, V.11
Zhang, L.-H.12
Wang, M.13
Chimini, G.14
Wellington, C.L.15
Tafuri, S.R.16
Hayden, M.R.17
-
38
-
-
1642300417
-
Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter
-
DOI 10.1074/jbc.M313487200
-
Haidar, B., Denis, M., Marcil, M., Krimbou, L., and, Genest, J., Jr., (2004) Apolipoprotein A-I activates cellular cAMP signaling through the ABCA1 transporter. J. Biol. Chem. 279, 9963-9969. (Pubitemid 38372598)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.11
, pp. 9963-9969
-
-
Haidar, B.1
Denis, M.2
Marcil, M.3
Krimbou, L.4
Genest Jr., J.5
-
39
-
-
1542320076
-
Janus kinase 2 modulates the apolipoprotein interactions with abca1 required for removing cellular cholesterol
-
DOI 10.1074/jbc.M312571200
-
Tang, C., Vaughan, A. M., and Oram, J. F., (2004) Janus kinase 2 modulates the apolipoprotein interactions with ABCA1 required for removing cellular cholesterol. J. Biol. Chem. 279, 7622-7628. (Pubitemid 38294642)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.9
, pp. 7622-7628
-
-
Tang, C.1
Vaughan, A.M.2
Oram, J.F.3
-
40
-
-
73449097086
-
Expression and stability of two isoforms of ABCG1 in human vascular cells
-
Gelissen, I. C., Cartland, S., Brown, A. J., Sandoval, C., Kim, M., et al. (2010) Expression and stability of two isoforms of ABCG1 in human vascular cells. Atherosclerosis 208, 75-82.
-
(2010)
Atherosclerosis
, vol.208
, pp. 75-82
-
-
Gelissen, I.C.1
Cartland, S.2
Brown, A.J.3
Sandoval, C.4
Kim, M.5
-
41
-
-
84866152233
-
Protein kinase A modulates the activity of a major human isoform of ABCG1
-
Gelissen, I. C., Sharpe, L. J., Sandoval, C., Rao, G., Kockx, M., et al. (2012) Protein kinase A modulates the activity of a major human isoform of ABCG1. J. Lipid Res. 53, 2133-2140.
-
(2012)
J. Lipid Res.
, vol.53
, pp. 2133-2140
-
-
Gelissen, I.C.1
Sharpe, L.J.2
Sandoval, C.3
Rao, G.4
Kockx, M.5
-
42
-
-
84872390119
-
Species variation in ABCG1 isoform expression: Implications for the use of animal models in elucidating ABCG1 function
-
Burns, V., Sharpe, L. J., Gelissen, I. C., and, Brown, A. J., (2013) Species variation in ABCG1 isoform expression: implications for the use of animal models in elucidating ABCG1 function. Atherosclerosis 226, 408-411.
-
(2013)
Atherosclerosis
, vol.226
, pp. 408-411
-
-
Burns, V.1
Sharpe, L.J.2
Gelissen, I.C.3
Brown, A.J.4
-
43
-
-
34250902930
-
Targeting the protein kinase C family: Are we there yet?
-
DOI 10.1038/nrc2168, PII NRC2168
-
Mackay, H. J., and, Twelves, C. J., (2007) Targeting the protein kinase C family: are we there yet? Nat. Rev. Cancer 7, 554-562. (Pubitemid 46985395)
-
(2007)
Nature Reviews Cancer
, vol.7
, Issue.7
, pp. 554-562
-
-
Mackay, H.J.1
Twelves, C.J.2
-
44
-
-
0025553492
-
Cholesterol efflux from adipose cells is coupled to diacylglycerol production and protein kinase C activation
-
Theret, N., Delbart, C., Aguie, G., Fruchart, J. C., Vassaux, G., et al. (1990) Cholesterol efflux from adipose cells is coupled to diacylglycerol production and protein kinase C activation. Biochem. Biophys. Res. Commun. 173, 1361-1368.
-
(1990)
Biochem. Biophys. Res. Commun.
, vol.173
, pp. 1361-1368
-
-
Theret, N.1
Delbart, C.2
Aguie, G.3
Fruchart, J.C.4
Vassaux, G.5
-
45
-
-
0025779078
-
Protein kinase C as a mediator of high density lipoprotein receptor-dependent efflux of intracellular cholesterol
-
Mendez, A. J., Oram, J. F., and Bierman, E. L., (1991) Protein kinase C as a mediator of high density lipoprotein receptor-dependent efflux of intracellular cholesterol. J. Biol. Chem. 266, 10104-10111. (Pubitemid 21906774)
-
(1991)
Journal of Biological Chemistry
, vol.266
, Issue.16
, pp. 10104-10111
-
-
Mendez, A.J.1
Oram, J.F.2
Bierman, E.L.3
-
46
-
-
0030783089
-
Selective down-regulation by protein kinase C inhibitors of apolipoprotein-mediated cellular cholesterol efflux in macrophages
-
DOI 10.1021/bi970079t
-
Li, Q., Tsujita, M., and, Yokoyama, S., (1997) Selective down-regulation by protein kinase C inhibitors of apolipoprotein-mediated cellular cholesterol efflux in macrophages. Biochemistry 36, 12045-12052. (Pubitemid 27440942)
-
(1997)
Biochemistry
, vol.36
, Issue.40
, pp. 12045-12052
-
-
Li, Q.1
Tsujita, M.2
Yokoyama, S.3
-
47
-
-
0347918856
-
Apolipoprotein A-I Activates Protein Kinase Cα Signaling to Phosphorylate and Stabilize ATP Binding Cassette Transporter A1 for the High Density Lipoprotein Assembly
-
DOI 10.1074/jbc.M306258200
-
Yamauchi, Y., Hayashi, M., Abe-Dohmae, S., and, Yokoyama, S., (2003) Apolipoprotein A-I activates protein kinase C alpha signaling to phosphorylate and stabilize ATP binding cassette transporter A1 for the high density lipoprotein assembly. J. Biol. Chem. 278, 47890-47897. (Pubitemid 37523237)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.48
, pp. 47890-47897
-
-
Yamauchi, Y.1
Hayashi, M.2
Abe-Dohmae, S.3
Yokoyama, S.4
-
48
-
-
27744455987
-
Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway
-
DOI 10.1074/jbc.M506210200
-
Wang, Y., and, Oram, J. F., (2005) Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a phospholipase D2 pathway. J. Biol. Chem. 280, 35896-35903. (Pubitemid 41633857)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.43
, pp. 35896-35903
-
-
Wang, Y.1
Oram, J.F.2
-
49
-
-
34248145949
-
Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a protein kinase C δ pathway
-
DOI 10.1194/jlr.M600437-JLR200
-
Wang, Y., and, Oram, J. F., (2007) Unsaturated fatty acids phosphorylate and destabilize ABCA1 through a protein kinase C delta pathway. J. Lipid Res. 48, 1062-1068. (Pubitemid 46708673)
-
(2007)
Journal of Lipid Research
, vol.48
, Issue.5
, pp. 1062-1068
-
-
Wang, Y.1
Oram, J.F.2
-
50
-
-
77949887017
-
Inhibition of ERK1/2 and activation of liver X receptor synergistically induce macrophage ABCA1 expression and cholesterol efflux
-
Zhou, X., Yin, Z., Guo, X., Hajjar, D. P., and, Han, J., (2010) Inhibition of ERK1/2 and activation of liver X receptor synergistically induce macrophage ABCA1 expression and cholesterol efflux. J. Biol. Chem. 285, 6316-6326.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 6316-6326
-
-
Zhou, X.1
Yin, Z.2
Guo, X.3
Hajjar, D.P.4
Han, J.5
-
51
-
-
0347362786
-
Involvement of Cdc42 Signaling in ApoA-I-induced Cholesterol Efflux
-
DOI 10.1074/jbc.M305673200
-
Nofer, J. R., Feuerborn, R., Levkau, B., Sokoll, A., Seedorf, U., et al. (2003) Involvement of Cdc42 signaling in apoA-I-induced cholesterol efflux. J. Biol. Chem. 278, 53055-53062. (Pubitemid 38035908)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.52
, pp. 53055-53062
-
-
Nofer, J.-R.1
Feuerborn, R.2
Levkau, B.3
Sokoll, A.4
Seedorf, U.5
Assmann, G.6
-
52
-
-
84858201901
-
The interaction of ApoA-I and ABCA1 triggers signal transduction pathways to mediate efflux of cellular lipids
-
Zhao, G. J., Yin, K., Fu, Y. C., and, Tang, C. K., (2012) The interaction of ApoA-I and ABCA1 triggers signal transduction pathways to mediate efflux of cellular lipids. Mol. Med. 18, 149-158.
-
(2012)
Mol. Med.
, vol.18
, pp. 149-158
-
-
Zhao, G.J.1
Yin, K.2
Fu, Y.C.3
Tang, C.K.4
-
53
-
-
0141844589
-
Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I
-
DOI 10.1074/jbc.M307161200
-
Martinez, L. O., Agerholm-Larsen, B., Wang, N., Chen, W., and, Tall, A. R., (2003) Phosphorylation of a pest sequence in ABCA1 promotes calpain degradation and is reversed by ApoA-I. J. Biol. Chem. 278, 37368-37374. (Pubitemid 37175255)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.39
, pp. 37368-37374
-
-
Martinez, L.O.1
Agerholm-Larsen, B.2
Wang, N.3
Chen, W.4
Tall, A.R.5
-
54
-
-
0037253264
-
A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I
-
DOI 10.1172/JCI200316808
-
Wang, N., Chen, W., Linsel-Nitschke, P., Martinez, L. O., Agerholm-Larsen, B., et al. (2003) A PEST sequence in ABCA1 regulates degradation by calpain protease and stabilization of ABCA1 by apoA-I. J. Clin. Invest. 111, 99-107. (Pubitemid 36134853)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.1
, pp. 99-107
-
-
Wang, N.1
Chen, W.2
Linsel-Nitschke, P.3
Martinez, L.O.4
Agerholm-Larsen, B.5
Silver, D.L.6
Tall, A.R.7
-
55
-
-
4444306835
-
Phosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter
-
DOI 10.1074/jbc.M401821200
-
Roosbeek, S., Peelman, F., Verhee, A., Labeur, C., Caster, H., et al. (2004) Phosphorylation by protein kinase CK2 modulates the activity of the ATP binding cassette A1 transporter. J. Biol. Chem. 279, 37779-37788. (Pubitemid 39195492)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.36
, pp. 37779-37788
-
-
Roosbeek, S.1
Peelman, F.2
Verhee, A.3
Labeur, C.4
Caster, H.5
Lensink, M.F.6
Ciruli, C.7
Grooten, J.8
Cochet, C.9
Vandekerckliove, J.10
Amoresano, A.11
Chimini, G.12
Tavernier, J.13
Rosseneu, M.14
-
56
-
-
8344222640
-
Cyclosporin A traps ABCA1 at the plasma membrane and inhibits ABCA1-mediated lipid efflux to apolipoprotein A-I
-
DOI 10.1161/01.ATV.0000144811.94581.52
-
Le Goff, W., Peng, D. Q., Settle, M., Brubaker, G., Morton, R. E., et al. (2004) Cyclosporin A traps ABCA1 at the plasma membrane and inhibits ABCA1-mediated lipid efflux to apolipoprotein A-I. Arterioscler. Thromb. Vasc. Biol. 24, 2155-2161. (Pubitemid 39482445)
-
(2004)
Arteriosclerosis, Thrombosis, and Vascular Biology
, vol.24
, Issue.11
, pp. 2155-2161
-
-
Le Goff, W.1
Peng, D.-Q.2
Settle, M.3
Brubaker, G.4
Morton, R.E.5
Smith, J.D.6
-
57
-
-
0026575932
-
The mechanism of action of cyclosporin A and FK506
-
Schreiber, S. L., and, Crabtree, G. R., (1992) The mechanism of action of cyclosporin A and FK506. Immunol. Today 13, 136-142.
-
(1992)
Immunol. Today
, vol.13
, pp. 136-142
-
-
Schreiber, S.L.1
Crabtree, G.R.2
-
58
-
-
77951070514
-
Cholesterol efflux to apoA-I in ABCA1-expressing cells is regulated by Ca2+-dependent calcineurin signaling
-
Karwatsky, J., Ma, L., Dong, F., and, Zha, X., (2010) Cholesterol efflux to apoA-I in ABCA1-expressing cells is regulated by Ca2+-dependent calcineurin signaling. J. Lipid Res. 51, 1144-1156.
-
(2010)
J. Lipid Res.
, vol.51
, pp. 1144-1156
-
-
Karwatsky, J.1
Ma, L.2
Dong, F.3
Zha, X.4
-
59
-
-
84890645468
-
Protein tyrosine phosphatase inhibition down-regulates ligand-induced ABCA1 expression
-
in press.
-
Luu, W., Sharpe, L. J., and, Brown, A. J., Protein tyrosine phosphatase inhibition down-regulates ligand-induced ABCA1 expression. Atherosclerosis, in press.
-
Atherosclerosis
-
-
Luu, W.1
Sharpe, L.J.2
Brown, A.J.3
-
60
-
-
72449192809
-
Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation
-
Cohen P., (2010) Guidelines for the effective use of chemical inhibitors of protein function to understand their roles in cell regulation. Biochem. J. 425, 53-54.
-
(2010)
Biochem. J.
, vol.425
, pp. 53-54
-
-
Cohen, P.1
-
61
-
-
0033613166
-
Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway
-
DOI 10.1073/pnas.96.20.11358
-
Takahashi, Y., and, Smith, J. D., (1999) Cholesterol efflux to apolipoprotein AI involves endocytosis and resecretion in a calcium-dependent pathway. Proc. Natl. Acad. Sci. USA 96, 11358-11363. (Pubitemid 29487385)
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, Issue.20
, pp. 11358-11363
-
-
Takahashi, Y.1
Smith, J.D.2
-
62
-
-
34548511124
-
Rottlerin: An inappropriate and ineffective inhibitor of PKC
-
DOI 10.1016/j.tips.2007.07.003, PII S016561470700185X
-
Soltoff, S. P., (2007) Rottlerin: an inappropriate and ineffective inhibitor of PKCdelta. Trends Pharmacol. Sci. 28, 453-458. (Pubitemid 47371266)
-
(2007)
Trends in Pharmacological Sciences
, vol.28
, Issue.9
, pp. 453-458
-
-
Soltoff, S.P.1
|