-
1
-
-
0037111732
-
Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease
-
Weinstein DA, Roy CN, Fleming MD, Loda MF, Wolfsdorf JI, Andrews NC. Inappropriate expression of hepcidin is associated with iron refractory anemia: implications for the anemia of chronic disease. Blood 2002;100:3776-81.
-
(2002)
Blood
, vol.100
, pp. 3776-3781
-
-
Weinstein, D.A.1
Roy, C.N.2
Fleming, M.D.3
Loda, M.F.4
Wolfsdorf, J.I.5
Andrews, N.C.6
-
2
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L, et al. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 2002;110:1037-44.
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
-
3
-
-
0038662619
-
Hepcidin a putative mediator of anemia of inflammation, is a type II acute-phase protein
-
Nemeth E, Valore EV, Territo M, Schiller G, Lichtenstein A, Ganz T. Hepcidin, a putative mediator of anemia of inflammation, is a type II acute-phase protein. Blood 2003;101:2461-3.
-
(2003)
Blood
, vol.101
, pp. 2461-2463
-
-
Nemeth, E.1
Valore, E.V.2
Territo, M.3
Schiller, G.4
Lichtenstein, A.5
Ganz, T.6
-
4
-
-
73149111744
-
Serum hepcidin: a novel diagnostic tool in disorders of iron metabolism
-
Bergamaschi G, Villani L. Serum hepcidin: a novel diagnostic tool in disorders of iron metabolism. Haematologica 2009;94:1631-3.
-
(2009)
Haematologica
, vol.94
, pp. 1631-1633
-
-
Bergamaschi, G.1
Villani, L.2
-
5
-
-
54949147441
-
Immunoassay for human serum hepcidin
-
Ganz T, Olbina G, Girelli D, Nemeth E, Westerman M. Immunoassay for human serum hepcidin. Blood 2008;112:4292-7.
-
(2008)
Blood
, vol.112
, pp. 4292-4297
-
-
Ganz, T.1
Olbina, G.2
Girelli, D.3
Nemeth, E.4
Westerman, M.5
-
6
-
-
33845245942
-
Suppression of hepcidin during anemia requires erythropoietic activity
-
Pak M, Lopez MA, Gabayan V, Ganz T, Rivera S. Suppression of hepcidin during anemia requires erythropoietic activity. Blood 2006;108:3730-5.
-
(2006)
Blood
, vol.108
, pp. 3730-3735
-
-
Pak, M.1
Lopez, M.A.2
Gabayan, V.3
Ganz, T.4
Rivera, S.5
-
7
-
-
33645314044
-
Molecular pathogenesis of anemia of chronic disease
-
Ganz T. Molecular pathogenesis of anemia of chronic disease. Pediatr Blood Cancer 2006;46:554-7.
-
(2006)
Pediatr Blood Cancer
, vol.46
, pp. 554-557
-
-
Ganz, T.1
-
8
-
-
33646370235
-
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
-
Babitt JL, Huang FW, Wrighting DM, et al. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet 2006;38:531-9.
-
(2006)
Nat Genet
, vol.38
, pp. 531-539
-
-
Babitt, J.L.1
Huang, F.W.2
Wrighting, D.M.3
-
9
-
-
63449103712
-
BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism
-
Andriopoulos B Jr, Corradini E, Xia Y, et al. BMP6 is a key endogenous regulator of hepcidin expression and iron metabolism. Nat Genet 2009;41:482-7.
-
(2009)
Nat Genet
, vol.41
, pp. 482-487
-
-
Andriopoulos Jr., B.1
Corradini, E.2
Xia, Y.3
-
10
-
-
63449122819
-
Lack of the bone morphogenetic protein BMP6 induces massive iron overload
-
Meynard D, Kautz L, Darnaud V, Canonne-Hergaux F, Coppin H, Roth MP. Lack of the bone morphogenetic protein BMP6 induces massive iron overload. Nat Genet 2009;41:478-81.
-
(2009)
Nat Genet
, vol.41
, pp. 478-481
-
-
Meynard, D.1
Kautz, L.2
Darnaud, V.3
Canonne-Hergaux, F.4
Coppin, H.5
Roth, M.P.6
-
11
-
-
46749158788
-
Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin
-
Xia Y, Babitt JL, Sidis Y, Chung RT, Lin HY. Hemojuvelin regulates hepcidin expression via a selective subset of BMP ligands and receptors independently of neogenin. Blood 2008;111:5195-204.
-
(2008)
Blood
, vol.111
, pp. 5195-5204
-
-
Xia, Y.1
Babitt, J.L.2
Sidis, Y.3
Chung, R.T.4
Lin, H.Y.5
-
12
-
-
77949774448
-
Molecular mechanisms of hepcidin regulation: implications for the anemia of CKD
-
Babitt JL, Lin HY. Molecular mechanisms of hepcidin regulation: implications for the anemia of CKD. Am J Kidney Dis 2010;55: 726-41.
-
(2010)
Am J Kidney Dis
, vol.55
, pp. 726-741
-
-
Babitt, J.L.1
Lin, H.Y.2
-
13
-
-
77949707023
-
Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin
-
Ashby DR, Gale DP, Busbridge M, et al. Erythropoietin administration in humans causes a marked and prolonged reduction in circulating hepcidin. Haematologica 2010;95:505-8.
-
(2010)
Haematologica
, vol.95
, pp. 505-508
-
-
Ashby, D.R.1
Gale, D.P.2
Busbridge, M.3
-
14
-
-
34948904750
-
High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin
-
Tanno T, Bhanu NV, Oneal PA, et al. High levels of GDF15 in thalassemia suppress expression of the iron regulatory protein hepcidin. Nat Med 2007;13:1096-101.
-
(2007)
Nat Med
, vol.13
, pp. 1096-1101
-
-
Tanno, T.1
Bhanu, N.V.2
Oneal, P.A.3
-
15
-
-
67651043722
-
Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells
-
Tanno T, Porayette P, Sripichai O, et al. Identification of TWSG1 as a second novel erythroid regulator of hepcidin expression in murine and human cells. Blood 2009;114:181-6.
-
(2009)
Blood
, vol.114
, pp. 181-186
-
-
Tanno, T.1
Porayette, P.2
Sripichai, O.3
-
16
-
-
79953108427
-
Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project
-
Piperno A, Galimberti S, Mariani R, et al. Modulation of hepcidin production during hypoxia-induced erythropoiesis in humans in vivo: data from the HIGHCARE project. Blood 2011;117:2953-9.
-
(2011)
Blood
, vol.117
, pp. 2953-2959
-
-
Piperno, A.1
Galimberti, S.2
Mariani, R.3
-
17
-
-
34447120059
-
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)
-
Peyssonnaux C, Zinkernagel AS, Schuepbach RA, et al. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). J Clin Invest 2007;117:1926-32.
-
(2007)
J Clin Invest
, vol.117
, pp. 1926-1932
-
-
Peyssonnaux, C.1
Zinkernagel, A.S.2
Schuepbach, R.A.3
-
18
-
-
33751579324
-
Impaired intestinal iron absorption in Crohn's disease correlates with disease activity and markers of inflammation
-
Semrin G, Fishman DS, Bousvaros A, et al. Impaired intestinal iron absorption in Crohn's disease correlates with disease activity and markers of inflammation. Inflamm Bowel Dis 2006;12:1101-6.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 1101-1106
-
-
Semrin, G.1
Fishman, D.S.2
Bousvaros, A.3
-
19
-
-
50349085287
-
Involvement of hepcidin in the anemia of multiple myeloma
-
Sharma S, Nemeth E, Chen YH, et al. Involvement of hepcidin in the anemia of multiple myeloma. Clin Cancer Res 2008;14:3262-7.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 3262-3267
-
-
Sharma, S.1
Nemeth, E.2
Chen, Y.H.3
-
20
-
-
33646427702
-
TLR4 dependent hepcidin expression by myeloid cells in response to bacterial pathogens
-
Peyssonnaux C, Zinkernagel AS, Datta V, Lauth X, Johnson RS, Nizet V. TLR4 dependent hepcidin expression by myeloid cells in response to bacterial pathogens. Blood 2006;107:3727-32.
-
(2006)
Blood
, vol.107
, pp. 3727-3732
-
-
Peyssonnaux, C.1
Zinkernagel, A.S.2
Datta, V.3
Lauth, X.4
Johnson, R.S.5
Nizet, V.6
-
21
-
-
66749138982
-
Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis
-
Ramsay AJ, Hooper JD, Folgueras AR, Velasco G, Lopez-Otin C. Matriptase-2 (TMPRSS6): a proteolytic regulator of iron homeostasis. Haematologica 2009;94:840-9.
-
(2009)
Haematologica
, vol.94
, pp. 840-849
-
-
Ramsay, A.J.1
Hooper, J.D.2
Folgueras, A.R.3
Velasco, G.4
Lopez-Otin, C.5
-
22
-
-
54349094273
-
A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron
-
Melis MA, Cau M, Congiu R, et al. A mutation in the TMPRSS6 gene, encoding a transmembrane serine protease that suppresses hepcidin production, in familial iron deficiency anemia refractory to oral iron. Haematologica 2008;93:1473-9.
-
(2008)
Haematologica
, vol.93
, pp. 1473-1479
-
-
Melis, M.A.1
Cau, M.2
Congiu, R.3
-
23
-
-
42649118442
-
Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA)
-
Finberg KE, Heeney MM, Campagna DR, et al. Mutations in TMPRSS6 cause iron-refractory iron deficiency anemia (IRIDA). Nat Genet 2008;40:569-71.
-
(2008)
Nat Genet
, vol.40
, pp. 569-571
-
-
Finberg, K.E.1
Heeney, M.M.2
Campagna, D.R.3
-
25
-
-
33745743014
-
Hepcidin and iron-loading anemias
-
Nemeth E, Ganz T. Hepcidin and iron-loading anemias. Haematologica 2006;91:727-32.
-
(2006)
Haematologica
, vol.91
, pp. 727-732
-
-
Nemeth, E.1
Ganz, T.2
-
26
-
-
34447306076
-
Liver iron concentrations and urinary hepcidin in beta-thalassemia
-
Origa R, Galanello R, Ganz T, et al. Liver iron concentrations and urinary hepcidin in beta-thalassemia. Haematologica 2007;92: 583-8.
-
(2007)
Haematologica
, vol.92
, pp. 583-588
-
-
Origa, R.1
Galanello, R.2
Ganz, T.3
-
27
-
-
0013954846
-
The anemia of chronic disorders
-
Cartwright GE. The anemia of chronic disorders. Semin Hematol 1966;3:351-75.
-
(1966)
Semin Hematol
, vol.3
, pp. 351-375
-
-
Cartwright, G.E.1
-
28
-
-
62149150326
-
Excess adiposity, inflammation, and iron-deficiency in female adolescents
-
Tussing-Humphreys LM, Liang H, Nemeth E, Freels S, Braunschweig CA. Excess adiposity, inflammation, and iron-deficiency in female adolescents. J Am Diet Assoc 2009;109:297-302.
-
(2009)
J Am Diet Assoc
, vol.109
, pp. 297-302
-
-
Tussing-Humphreys, L.M.1
Liang, H.2
Nemeth, E.3
Freels, S.4
Braunschweig, C.A.5
-
29
-
-
69249208830
-
Hepcidin-a potential novel biomarker for iron status in chronic kidney disease
-
Zaritsky J, Young B, Wang HJ, et al. Hepcidin-a potential novel biomarker for iron status in chronic kidney disease. Clin J Am Soc Nephrol 2009;4:1051-6.
-
(2009)
Clin J Am Soc Nephrol
, vol.4
, pp. 1051-1056
-
-
Zaritsky, J.1
Young, B.2
Wang, H.J.3
-
30
-
-
34447117474
-
Hepcidin regulation: ironing out the details
-
De Domenico I, Ward DM, Kaplan J. Hepcidin regulation: ironing out the details. J Clin Invest 2007;117:1755-8.
-
(2007)
J Clin Invest
, vol.117
, pp. 1755-1758
-
-
De Domenico, I.1
Ward, D.M.2
Kaplan, J.3
-
31
-
-
77953372800
-
Targeting the hepcidin-ferroportin axis in the diagnosis and treatment of anemias
-
2010 750643
-
Nemeth E. Targeting the hepcidin-ferroportin axis in the diagnosis and treatment of anemias. Adv Hematol 2010;2010: 750643.
-
(2010)
Adv Hematol;
-
-
Nemeth, E.1
-
32
-
-
71049141352
-
Development of a novel immunoassay for the iron regulatory peptide hepcidin
-
Busbridge M, Griffiths C, Ashby D, et al. Development of a novel immunoassay for the iron regulatory peptide hepcidin. Br J Biomed Sci 2009;66:150-7.
-
(2009)
Br J Biomed Sci
, vol.66
, pp. 150-157
-
-
Busbridge, M.1
Griffiths, C.2
Ashby, D.3
-
33
-
-
34147197662
-
Mass spectrometry-based hepcidin measurements in serum and urine: analytical aspects and clinical implications
-
Kemna EH, Tjalsma H, Podust VN, Swinkels DW. Mass spectrometry-based hepcidin measurements in serum and urine: analytical aspects and clinical implications. Clin Chem 2007;53:8-620.
-
(2007)
Clin Chem
, vol.53
, pp. 8-620
-
-
Kemna, E.H.1
Tjalsma, H.2
Podust, V.N.3
Swinkels, D.W.4
-
34
-
-
66149182892
-
Quantification of hepcidin using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry
-
Bansal SS, Halket JM, Fusova J, et al. Quantification of hepcidin using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry. Rapid Commun Mass Spectrom 2009;23: 1531-42.
-
(2009)
Rapid Commun Mass Spectrom
, vol.23
, pp. 1531-1542
-
-
Bansal, S.S.1
Halket, J.M.2
Fusova, J.3
-
35
-
-
73149122764
-
Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization
-
Kroot JJ, Kemna EH, Bansal SS, et al. Results of the first international round robin for the quantification of urinary and plasma hepcidin assays: need for standardization. Haematologica 2009;94:1748-52.
-
(2009)
Haematologica
, vol.94
, pp. 1748-1752
-
-
Kroot, J.J.1
Kemna, E.H.2
Bansal, S.S.3
-
36
-
-
67349113791
-
(Pre)analytical imprecision, between-subject variability, and daily variations in serum and urine hepcidin: implications for clinical studies
-
Kroot JJ, Hendriks JC, Laarakkers CM, et al. (Pre)analytical imprecision, between-subject variability, and daily variations in serum and urine hepcidin: implications for clinical studies. Anal Biochem 2009;389:124-9.
-
(2009)
Anal Biochem
, vol.389
, pp. 124-129
-
-
Kroot, J.J.1
Hendriks, J.C.2
Laarakkers, C.M.3
-
37
-
-
0037076925
-
Iron, infection and anemia-a classical triad
-
Weiss G. Iron, infection and anemia-a classical triad. Wien Klin Wochenschr 2002;114:357-67.
-
(2002)
Wien Klin Wochenschr
, vol.114
, pp. 357-367
-
-
Weiss, G.1
-
38
-
-
0036308047
-
Pathogenesis and treatment of anaemia of chronic disease
-
Weiss G. Pathogenesis and treatment of anaemia of chronic disease. Blood Rev 2002;16:87-96.
-
(2002)
Blood Rev
, vol.16
, pp. 87-96
-
-
Weiss, G.1
-
39
-
-
34447137331
-
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
-
Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, Lin HY. Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest 2007;117:1933-9.
-
(2007)
J Clin Invest
, vol.117
, pp. 1933-1939
-
-
Babitt, J.L.1
Huang, F.W.2
Xia, Y.3
Sidis, Y.4
Andrews, N.C.5
Lin, H.Y.6
-
40
-
-
27144488346
-
Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease
-
Nishimoto N, Kanakura Y, Aozasa K, et al. Humanized anti-interleukin-6 receptor antibody treatment of multicentric Castleman disease. Blood 2005;106:2627-32.
-
(2005)
Blood
, vol.106
, pp. 2627-2632
-
-
Nishimoto, N.1
Kanakura, Y.2
Aozasa, K.3
-
41
-
-
34347219438
-
-
Kawabata H, Tomosugi N, Kanda J, Tanaka Y, Yoshizaki K, Uchiyama T. Anti-interleukin 6 receptor antibody tocilizumab reduces the level of serum hepcidin in patients with multicentric Castleman's disease. Haematologica 2007;92:857-8.
-
(2007)
Uchiyama T. Anti-interleukin 6 receptor antibody tocilizumab reduces the level of serum hepcidin in patients with multicentric Castleman's disease. Haematologica
, vol.92
, pp. 857-858
-
-
Kawabata, H.1
Tomosugi, N.2
Kanda, J.3
Tanaka, Y.4
Yoshizaki, K.5
-
42
-
-
51649085681
-
Induction of erythropoiesis and iron utilization by the HIF prolyl hydroxylase inhibitor FG-4592
-
(abst 050)
-
Klaus S, Arend M, Fourney P, et al. Induction of erythropoiesis and iron utilization by the HIF prolyl hydroxylase inhibitor FG-4592. J Am Soc Nephrol 2005;16(Suppl):49A(abst 050).
-
(2005)
J Am Soc Nephrol
, vol.16
, Issue.SUPPL.
-
-
Klaus, S.1
Arend, M.2
Fourney, P.3
|