Investigation of Cu2+ binding to human and rat amyloid fragments Aβ (1-16) with a protein nanopore

Langmuir

Volumn 29, Issue 50, 2013, Pages 15634-15642

  Asandei, Alina ^a   Schiopu, Irina ^a   Iftemi, Sorana ^a   Mereuta, Loredana ^a   Luchian, Tudor ^a  

^a ALEXANDRU IOAN CUZA UNIVERSITY OF IASI   (Romania)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID-BETA PEPTIDES; ASSOCIATION AND DISSOCIATION KINETICS; METAL COORDINATION; MORPHOLOGY CHANGES; PEPTIDE FRAGMENTS; PRIMARY SEQUENCES; REVERSIBLE INTERACTIONS; STRUCTURAL ALTERATIONS;

ASSOCIATION REACTIONS; ELECTROPHYSIOLOGY; GLYCOPROTEINS; MOLECULES; NEUROLOGY; RATS;

PEPTIDES;

AMYLOID BETA PROTEIN; COPPER; PROTEIN BINDING;

ANIMAL; CHEMISTRY; HUMAN; METABOLISM; NANOPORE; RAT;

AMYLOID BETA-PEPTIDES; ANIMALS; COPPER; HUMANS; NANOPORES; PROTEIN BINDING; RATS;

EID: 84890586010     PISSN: 07437463     EISSN: 15205827     Source Type: Journal    
DOI: 10.1021/la403915t     Document Type: Article

References (42)

1. Bayley, H.; Cremer, P. S. Stochastic Sensors Inspired by Biology Nature 2001, 413, 226-230
2. Gu, L.-Q.; Shim, J. W. Single Molecule Sensing by Nanopores and Nanopore Devices Analyst 2010, 135, 441-451
3. Majd, S.; Yusko, E. C.; Billeh, Y. N.; Macrae, M. X.; Yang, J.; Mayer, M. Applications of Biological Pores in Nanomedicine, Sensing, and Nanoelectronics Curr. Opin. Biotechnol. 2010, 21, 439-476
4. Reiner, J. E.; Balijepalli, A.; Robertson, J. W. F.; Campbell, J.; Suehle, J.; Kasianowicz, J. J. Disease Detection and Management via Single Nanopore-Based Sensors Chem. Rev. 2012, 112, 6431-6451
5. DeBlois, R. W.; Bean, C. P. Counting and Sizing of Submicron Particles by the Resistive Pulse Technique Rev. Sci. Instrum. 1970, 41, 909-916
6. Asandei, A.; Apetrei, A.; Park, Y.; Hahm, K.-S.; Luchian, T. Investigation of Single-Molecule Kinetics Mediated by Weak Hydrogen-Bonds within a Biological Nanopore Langmuir 2011, 27, 19-24
7. Shin, S.-H.; Luchian, T.; Cheley, S.; Braha, O.; Bayley, H. Kinetics of a Reversible Covalent-Bond Forming Reaction Observed at the Single Molecule Level Angew. Chem., Int. Ed. 2002, 41, 3707-3709
8. Asandei, A.; Mereuta, L.; Luchian, T. The Kinetics of Ampicillin Complexation by γ-Cyclodextrins. A Single Molecule Approach J. Phys. Chem. B 2011, 115, 10173-10181
9. Gu, L.-Q.; Braha, O.; Conlan, S.; Cheley, S.; Bayley, H. Stochastic Sensing of Organic Analytes by a Pore-Forming Protein Containing a Molecular Adapter Nature 1999, 398, 686-690
10. Clarke, J.; Wu, H.; Jayasinghe, L.; Patel, A.; Reid, S.; Bayley, H. Continuous Base Identification for Single-Molecule Nanopore DNA Sequencing Nat. Nanotechnol. 2009, 4, 265-270
11. Wang, H.-Y.; Ying, Y.-L.; Li, Y.; Kraatz, H.-B.; Long, Y.-T. Nanopore Analysis of β-Amyloid Peptide Aggregation Transition Induced by Small Molecules Anal. Chem. 2011, 83, 1746-1752
12. Asandei, A.; Apetrei, A.; Luchian, T. Uni-molecular Detection and Quantification of Selected β-Lactam Antibiotics with a Hybrid α-Hemolysin Protein Pore J. Mol. Recognit. 2011, 24, 199-207
13. Ying, Y.-L.; Li, D.-W.; Li, Y.; Lee, J. S.; Long, Y.-T. Enhanced Translocation of Poly(dt)45 through an α-Hemolysin Nanopore by Binding with Antibody Chem. Commun. 2011, 47, 5690-5692
14. Movileanu, L.; Schmittschmitt, J.; Scholtz, J. M.; Bayley, H. Interaction of Peptides with a Protein Nanopore Biophys. J. 2005, 89, 1030-1045
15. Boersma, A. J.; Bayley, H. Continuous Stochastic Detection of Amino Acid Enantiomers with a Protein Nanopore Angew. Chem., Int. Ed. 2012, 51, 9606-9609
16. Boersma, A. J.; Brain, K. L.; Bayley, H. Real-Time Stochastic Detection of Multiple Neurotransmitters with a Protein Nanopore ACS Nano 2012, 6, 5304-5308
17. Bayley, H.; Luchian, T.; Shin, S.-H.; Steffensen, M. In Single Molecules and Nanotechnology; Vogel, H.; Rigler, R., Eds.; Springer: Heidelberg, Germany, 2008; pp 251-277.
18. Kasianowicz, J. J.; Robertson, J. W. F.; Chan, E. R.; Reiner, J. E.; Stanford, V. M. Nanoscopic Porous Sensors Annu. Rev. Anal. Chem. 2008, 1, 737-766
19. Wanunu, M. Nanopores: A Journey towards DNA Sequencing Phys. Life Rev. 2012, 9, 125-158
20. Stefureac, R.; Waldner, L.; Howard, S. P.; Lee, J. S. Nanopore Analysis of a Small 86-Residue Protein Small 2008, 4, 59-63
21. Baran, C.; Smith, G. S. T.; Bamm, V. V.; Harauz, G.; Lee, J. S. Divalent Cations Induce a Compaction of Intrinsically Disordered Myelin Basic Protein Biochem. Biophys. Res. Commun. 2010, 391, 224-229
22. Mereuta, L.; Schiopu, I.; Asandei, A.; Park, Y.; Hahm, K.-S.; Luchian, T. Protein Nanopore-Based, Single-Molecule Exploration of Copper Binding to an Antimicrobial-Derived, Histidine-Containing Chimera Peptide Langmuir 2012, 28, 17079-17091
23. Butterfield, S. M.; Lashuel, H. A. Amyloidogenic Protein-Membrane Interactions: Mechanistic Insight from Model Systems Angew. Chem., Int. Ed. 2010, 49, 2-29
24. Stellato, F.; Menestrina, G.; Dalla Serra, M.; Potrich, C.; Tomazzolli, R.; Meyer-Klaucke, W.; Morante, S. Metal Binding in Amyloid β-Peptides Shows Intra- and Inter-peptide Coordination Modes Eur. Biophys. J. 2006, 35, 340-351
25. Curtain, C. C.; Ali, F. E.; Smith, D. G.; Bush, A. I.; Masters, C. L.; Barnham, K. J. Metal Ions, pH, and Cholesterol Regulate the Interactions of Alzheimer's Disease Amyloid-β Peptide with Membrane Lipid J. Biol. Chem. 2003, 278, 2977-2982
26. 3+ on Amyloid-β Stability, Oligomerization, and Aggregation: Amyloid-β Destabilization Promotes Annular Protofibril Formation J. Biol. Chem. 2011, 286, 9646-9656
27. 2+-Induced Aggregation J. Phys. Chem. B 2010, 114, 11261-11271
28. Syme, C. D.; Nadal, R. C.; Rigby, S. E. J.; Viles, J. H. Copper Binding to the Amyloid-β (Aβ) Peptide Associated with Alzheimer's Disease J. Biol. Chem. 2004, 279, 18169-18177
29. Atwood, C. S.; Scarpa, R. C.; Huang, X.; Moir, R. D.; Jones, W. D.; Fairlie, D. P.; Tanzi, R. E.; Bush, A. I. Characterization of Copper Interactions with Alzheimer Amyloid β Peptides: Identification of an Attomolar-Affinity Copper Binding Site on Amyloid β1-42 J. Neurochem. 2000, 75, 1219-1233
30. Tougu, V.; Karafin, A.; Palumaa, P. Binding of Zinc(II) and Copper(II) to the Full-Length Alzheimer's Amyloid-β Peptide J. Neurochem. 2008, 104, 1249-1259
31. Sacco, C.; Skowronsky, R. A.; Gade, S.; Kenney, J. M.; Spuches, A. M. Calorimetric investigation of copper (II) binding to Aβ peptides: thermodynamics of coordination plasticity. J. Biol. Inorg. Chem. 2012, 17, 531-541
32. Mereuta, L.; Luchian, T.; Park, Y.; Hahm, K. S. Single-Molecule Investigation of the Interactions between Reconstituted Planar Lipid Membranes and an Analogue of the HP(2-20) Antimicrobial Peptide Biochem. Biophys. Res. Commun. 2008, 373, 467-472
33. Chiriac, R.; Luchian, T. pH Modulation of Transport Properties of Alamethicin Oligomers Inserted in Zwitterionic-Based Artificial Lipid Membranes Biophys. Chem. 2007, 130, 139-147
34. Grosberg, A. Y.; Rabin, Y. DNA Capture into a Nanopore: Interplay of Diffusion and Electrohydrodynamics J. Chem. Phys. 2010, 133, 165102
35. Wanunu, M.; Morrison, W.; Rabin, Y.; Grosberg, A. Y.; Meller, A. Electrostatic Focusing of Unlabeled DNA into Nanoscale Pores using a Salt Gradient Nat. Nanotechnol. 2010, 5, 160-165
36. Yao, F.; Zhang, R.; Tian, H.; Li, X. Studies on the Interactions of Copper and Zinc Ions with β-Amyloid Peptides by a Surface Plasmon Resonance Biosensor Int. J. Mol. Sci. 2012, 13, 11832-11843
37. Hatcher, L. Q.; Hong, L.; Bush, W. D.; Carducci, T.; Simon, J. Quantification of the Binding Constant of Copper(II) to the Amyloid-β Peptide J. Phys. Chem. B 2008, 112, 8160-8164
38. Arena, G.; Pappalardo, G.; Sovago, I.; Rizzarelli, E. Copper(II) Interaction with Amyloid-β: Affinity and Speciation Coord. Chem. Rev. 2012, 256, 3-12
39. Minicozzi, V.; Stellato, F.; Comai, M.; Dalla Serra, M.; Potrich, C.; Klaucke, W. M.; Morante, S. Identifying the Minimal Copper- and Zinc-binding Site Sequence in Amyloid-Peptides J. Biol. Chem. 2008, 283 (16) 10784-10792
40. Qing-Feng Ma, Q. F.; Jia Hu, J.; Wu, W. H.; Liu, H. D.; Du, J. T.; Fu, Y.; Wu, Y. W.; Lei, P.; Zhao, Y. F.; Li, Y. M. Characterization of Copper Binding to the Peptide Amyloid β (1-16) Associated with Alzheimer's Disease Biopolymers 2006, 83, 20-31
41. Danielsson, J.; Pierattelli, R.; Banci, L.; Graslund, A. High-Resolution NMR Studies of the Zinc-Binding Site of the Alzheimer's Amyloid β-Peptide FEBS J. 2007, 274, 46-59
42. Stefureac, R.; Long, Y.-T.; Kraatz, H.-B.; Howard, P.; Lee, J. S. Transport of α-Helical Peptides through α-Hemolysin and Aerolysin Pores Biochemistry 2006, 45, 9172-9179