Cyclin-dependent kinase 1 plays a critical role in DNA replication control during rat liver regeneration

Hepatology

Volumn 50, Issue 6, 2009, Pages 1946-1956

  Garnier, Delphine ^a,b,c,d   Loyer, Pascal ^a,b,c,d   Ribault, Catherine ^a,b,c,d   Guguen Guillouzo, Christiane ^a,b,c,d   Corlu, Anne ^a,b,c,d  

^a PONTCHAILLOU UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE RENNES 1   (France)

^c UNIVERSITÉ EUROPÉENNE DE BRETAGNE   (France)

^d IFR 140   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN A; CYCLIN B1; CYCLIN DEPENDENT KINASE 1; MINICHROMOSOME MAINTENANCE PROTEIN 7; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CELL CYCLE ARREST; CELL CYCLE REGULATION; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA REPLICATION; ENZYME ACTIVITY; ENZYME BINDING; ENZYME LOCALIZATION; LIVER CELL CULTURE; LIVER REGENERATION; MALE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SKIN FIBROBLAST;

ANIMALS; CDC2 PROTEIN KINASE; CELL CYCLE; CELLS, CULTURED; CYCLIN A; CYCLIN B1; DNA REPLICATION; FIBROBLASTS; HEPATOCYTES; LIVER REGENERATION; MALE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 73149094101     PISSN: 02709139     EISSN: None     Source Type: Journal    
DOI: 10.1002/hep.23225     Document Type: Article

References (34)

1. Malumbres M, Barbacid M. Mammalian cyclin-dependent kinases. Trends Biochem Sci 2005;30:630-641.
2. Morgan DO. Cyclin-dependent kinases: engines, clocks, and microprocessors. Annu Rev Cell Dev Biol 1997;13:261-291.
3. Sherr CJ. G1 phase progression: cycling on cue. Cell 1994;79:551-555.
4. Matsumoto Y, Hayashi K, Nishida E. Cyclin-dependent kinase 2 (Cdk2) is required for centrosome duplication in mammalian cells. Curr Biol 1999;9:429-432.
5. Bashir T, Pagano M. Cdk1: the dominant sibling of Cdk2. Nat Cell Biol 2005;7:779-781.
6. Tetsu O, McCormick F. Proliferation of cancer cells despite CDK2 inhibition. Cancer Cell 2003;3:233-245.
7. Ortega S, Prieto I, Odajima J, Martin A, Dubus P, Sotillo R, et al. Cyclindependent kinase 2 is essential for meiosis but not for mitotic cell division in mice. Nat Genet 2003;35:25-31.
8. Berthet C, Aleem E, Coppola V, Tessarollo L, Kaldis P. Cdk2 knockout mice are viable. Curr Biol 2003;13:1775-1785.
9. Li W, Kotoshiba S, Berthet C, Hilton MB, Kaldis P. Rb/Cdk2/Cdk4 triple mutant mice elicit an alternative mechanism for regulation of the G1/S transition. Proc Natl Acad Sci U S A 2009;106:486-491.
10. Malumbres M, Barbacid M. Cell cycle, CDKs and cancer: a changing paradigm. Nat Rev Cancer 2009;9:153-166.
11. Santamaria D, Barriere C, Cerqueira A, Hunt S, Tardy C, Newton K, et al. Cdk1 is sufficient to drive the mammalian cell cycle. Nature 2007;448:811-815.
12. Aleem E, Kiyokawa H, Kaldis P. Cdc2-cyclin E complexes regulate the G1/S phase transition. Nat Cell Biol 2005;7:831-836.
13. Hochegger H, Dejsuphong D, Sonoda E, Saberi A, Rajendra E, Kirk J, et al. An essential role for Cdk1 in S phase control is revealed via chemical genetics in vertebrate cells. J Cell Biol 2007;178:257-268.
14. Kaldis P, Aleem E. Cell cycle sibling rivalry: Cdc2 vs. Cdk2. Cell Cycle 2005;4:1491-1494.
15. Krasinska L, Besnard E, Cot E, Dohet C, Mechali M, Lemaitre JM, et al. Cdk1 and Cdk2 activity levels determine the efficiency of replication origin firing in Xenopus. EMBO J 2008;27:758-769.
16. Michalopoulos GK, DeFrances MC. Liver regeneration. Science 1997;276:60-66.
17. Loyer P, Cariou S, Glaise D, Bilodeau M, Baffet G, Guguen-Guillouzo C. Growth factor dependence of progression through G1 and S phases of adult rat hepatocytes in vitro. Evidence of a mitogen restriction point in mid-late G1. J Biol Chem 1996;271:11484-11492.
18. Albrecht JH, Poon RY, Ahonen CL, Rieland BM, Deng C, Crary GS. Involvement of p21 and p27 in the regulation of CDK activity and cell cycle progression in the regenerating liver. Oncogene 1998;16:2141-2150.
19. Jaumot M, Estanyol JM, Serratosa J, Agell N, Bachs O. Activation of cdk4 and cdk2 during rat liver regeneration is associated with intranuclear rearrangements of cyclin-cdk complexes. HEPATOLOGY 1999;29:385-395.
20. Satyanarayana A, Berthet C, Lopez-Molina J, Coppola V, Tessarollo L, Kaldis P. Genetic substitution of Cdk1 by Cdk2 leads to embryonic lethality and loss of meiotic function of Cdk2. Development 2008;135:3389-3400.
21. Satyanarayana A, Hilton MB, Kaldis P. p21 inhibits Cdk1 in the absence of Cdk2 to maintain the G1/S phase DNA damage checkpoint. Mol Biol Cell 2008;19:65-77.
22. Loyer P, Glaise D, Cariou S, Baffet G, Meijer L, Guguen-Guillouzo C. Expression and activation of cdks (1 and 2) and cyclins in the cell cycle progression during liver regeneration. J Biol Chem 1994;269:2491-2500.
23. Wheeler LW, Lents NH, Baldassare JJ. Cyclin A-CDK activity during G1 phase impairs MCM chromatin loading and inhibits DNA synthesis in mammalian cells. Cell Cycle 2008;7:2179-2188.
24. Fausto N. Liver regeneration. J Hepatol 2000;32:19-31.
25. Rakba N, Loyer P, Gilot D, Delcros JG, Glaise D, Baret P, et al. Antiproliferative and apoptotic effects of O-Trensox, a new synthetic iron chelator, on differentiated human hepatoma cell lines. Carcinogenesis 2000;21:943-951.
26. Katsuno Y, Suzuki A, Sugimura K, Okumura K, Zineldeen DH, Shimada M, et al. Cyclin A-Cdk1 regulates the origin firing program in mammalian cells. Proc Natl Acad Sci U S A 2009;106:3184-3189.
27. Moore JD, Kirk JA, Hunt T. Unmasking the S-phase-promoting potential of cyclin B1. Science 2003;300:987-990.
28. Pines J, Hunter T. The differential localization of human cyclins A and B is due to a cytoplasmic retention signal in cyclin B. EMBO J 1994;13:3772-3781.
29. Hochegger H, Takeda S, Hunt T. Cyclin-dependent kinases and cell-cycle transitions: does one fit all? Nat Rev Mol Cell Biol 2008;9:910-916.
30. Pomerening JR, Ubersax JA, Ferrell JE Jr. Rapid cycling and precocious termination of G1 phase in cells expressing CDK1AF. Mol Biol Cell 2008;19:3426-3441.
31. Guidotti JE, Bregerie O, Robert A, Debey P, Brechot C, Desdouets C. Liver cell polyploidization: a pivotal role for binuclear hepatocytes. J Biol Chem 2003;278:19095-19101.
32. Ilyin GP, Glaise D, Gilot D, Baffet G, Guguen-Guillouzo C. Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth. Am J Physiol Gastrointest Liver Physiol 2003;285:G115-127.
33. Furukawa Y, Piwnica-Worms H, Ernst TJ, Kanakura Y, Griffin JD. Cdc2 gene expression at the G1 to S transition in human T lymphocytes. Science 1990;250:805-808.
34. Serandour AL, Loyer P, Garnier D, Courselaud B, Theret N, Glaise D, et al. TNFalpha-mediated extracellular matrix remodeling is required for multiple division cycles in rat hepatocytes. HEPATOLOGY 2005;41:478-486.