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Volumn 27, Issue 12, 2013, Pages 4929-4939

Regulation of UHRF1 by miR-146a/b modulates gastric cancer invasion and metastasis

Author keywords

DNA methylation; Metastasis

Indexed keywords

BETA ACTIN; CADHERIN; CADHERIN 4; MICRORNA 146A; MICRORNA 146B; PROTEIN SLIT3; PROTEIN UHRF1; SLIT PROTEIN; TRANSCRIPTION FACTOR RUNX3; UBIQUITIN; UNCLASSIFIED DRUG;

EID: 84890524833     PISSN: None     EISSN: 15306860     Source Type: Journal    
DOI: 10.1096/fj.13-233387     Document Type: Article
Times cited : (95)

References (56)
  • 3
    • 84865510127 scopus 로고    scopus 로고
    • Inflammationassociated cancer development in digestive organs: Mechanisms and roles for genetic and epigenetic modulation
    • Chiba, T., Marusawa, H., and Ushijima, T. (2012) Inflammationassociated cancer development in digestive organs: mechanisms and roles for genetic and epigenetic modulation. Gastroenterology 143, 550-563
    • (2012) Gastroenterology , vol.143 , pp. 550-563
    • Chiba, T.1    Marusawa, H.2    Ushijima, T.3
  • 4
    • 83955164212 scopus 로고    scopus 로고
    • Carcinogenesis, prevention and early detection of gastric cancer: Where we are and where we should go
    • Gonzalez, C. A., and Agudo, A. (2012) Carcinogenesis, prevention and early detection of gastric cancer: where we are and where we should go. Int. J. Cancer 130, 745-753
    • (2012) Int. J. Cancer , vol.130 , pp. 745-753
    • Gonzalez, C.A.1    Agudo, A.2
  • 5
    • 79960113856 scopus 로고    scopus 로고
    • Epigenetic modifications of metastasis suppressor genes in colon cancer metastasis
    • Li, Q., and Chen, H. (2011) Epigenetic modifications of metastasis suppressor genes in colon cancer metastasis. Epigenetics 6, 849-852
    • (2011) Epigenetics , vol.6 , pp. 849-852
    • Li, Q.1    Chen, H.2
  • 6
    • 84865566726 scopus 로고    scopus 로고
    • Dna methylation of microrna genes in multiple myeloma
    • Wong, K. Y., Huang, X., and Chim, C. S. (2012) DNA methylation of microRNA genes in multiple myeloma. Carcinogenesis 33, 1629-1638
    • (2012) Carcinogenesis , vol.33 , pp. 1629-1638
    • Wong, K.Y.1    Huang, X.2    Chim, C.S.3
  • 7
    • 84860408968 scopus 로고    scopus 로고
    • Dna methylationassociated silencing of tumor-suppressor micrornas in cancer
    • Lopez-Serra, P., and Esteller, M. (2012) DNA methylationassociated silencing of tumor-suppressor microRNAs in cancer. Oncogene 31, 1609-1622
    • (2012) Oncogene , vol.31 , pp. 1609-1622
    • Lopez-Serra, P.1    Esteller, M.2
  • 9
    • 34648833002 scopus 로고    scopus 로고
    • Uhrf1 plays a role in maintaining dna methylation in mammalian cells
    • Bostick, M., Kim, J. K., Esteve, P. O., Clark, A., Pradhan, S., and Jacobsen, S. E. (2007) UHRF1 plays a role in maintaining DNA methylation in mammalian cells. Science 317, 1760-1764
    • (2007) Science , vol.317 , pp. 1760-1764
    • Bostick, M.1    Kim, J.K.2    Esteve, P.O.3    Clark, A.4    Pradhan, S.5    Jacobsen, S.E.6
  • 10
    • 34548013072 scopus 로고    scopus 로고
    • Epigenetic modulation of estrogen receptor-alpha by prb family proteins: A novel mechanism in breast cancer
    • Macaluso, M., Montanari, M., Noto, P. B., Gregorio, V., Bronner, C., and Giordano, A. (2007) Epigenetic modulation of estrogen receptor-alpha by pRb family proteins: a novel mechanism in breast cancer. Cancer Res. 67, 7731-7737
    • (2007) Cancer Res. , vol.67 , pp. 7731-7737
    • Macaluso, M.1    Montanari, M.2    Noto, P.B.3    Gregorio, V.4    Bronner, C.5    Giordano, A.6
  • 14
    • 84864981284 scopus 로고    scopus 로고
    • Uhrf1 promotes cell growth and metastasis through repression of p16(ink(4)a) in colorectal cancer
    • Wang, F., Yang, Y. Z., Shi, C. Z., Zhang, P., Moyer, M. P., Zhang, H. Z., Zou, Y., and Qin, H. L. (2012) UHRF1 promotes cell growth and metastasis through repression of p16(ink(4)a) in colorectal cancer. Ann. Surg. Oncol. 19, 2753-2762
    • (2012) Ann. Surg. Oncol. , Issue.19 , pp. 2753-2762
    • Wang, F.1    Yang, Y.Z.2    Shi, C.Z.3    Zhang, P.4    Moyer, M.P.5    Zhang, H.Z.6    Zou, Y.7    Qin, H.L.8
  • 16
    • 67649859436 scopus 로고    scopus 로고
    • Uhrf1 is a novel molecular marker for diagnosis and the prognosis of bladder cancer
    • Unoki, M., Kelly, J. D., Neal, D. E., Ponder, B. A., Nakamura, Y., and Hamamoto, R. (2009) UHRF1 is a novel molecular marker for diagnosis and the prognosis of bladder cancer. Br. J. Cancer 101, 98-105
    • (2009) Br. J. Cancer , vol.101 , pp. 98-105
    • Unoki, M.1    Kelly, J.D.2    Neal, D.E.3    Ponder, B.A.4    Nakamura, Y.5    Hamamoto, R.6
  • 17
    • 79955109834 scopus 로고    scopus 로고
    • Down-regulation of uhrf1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties
    • Alhosin, M., Sharif, T., Mousli, M., Etienne-Selloum, N., Fuhrmann, G., Schini-Kerth, V. B., and Bronner, C. (2011) Down-regulation of UHRF1, associated with re-expression of tumor suppressor genes, is a common feature of natural compounds exhibiting anti-cancer properties. J. Exp. Clin. Cancer Res. 30, 41
    • (2011) J. Exp. Clin. Cancer Res. , vol.30 , pp. 41
    • Alhosin, M.1    Sharif, T.2    Mousli, M.3    Etienne-Selloum, N.4    Fuhrmann, G.5    Schini-Kerth, V.B.6    Bronner, C.7
  • 19
    • 58249088751 scopus 로고    scopus 로고
    • Micrornas: Target recognition and regulatory functions
    • Bartel, D. P. (2009) MicroRNAs: target recognition and regulatory functions. Cell 136, 215-233
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 20
    • 33745248430 scopus 로고    scopus 로고
    • Microrna target predictions in animals
    • Rajewsky, N. (2006) microRNA target predictions in animals. Nat. Genet. 38(Suppl), S8-S13
    • (2006) Nat. Genet. , vol.38 , Issue.SUPPL.
    • Rajewsky, N.1
  • 21
    • 33645294070 scopus 로고    scopus 로고
    • Oncomirs-Micrornas with a role in cancer
    • Esquela-Kerscher, A., and Slack, F. J. (2006) Oncomirs-microRNAs with a role in cancer. Nat. Rev. Cancer 6, 259-269
    • (2006) Nat. Rev. Cancer , vol.6 , pp. 259-269
    • Esquela-Kerscher, A.1    Slack, F.J.2
  • 22
    • 33845624889 scopus 로고    scopus 로고
    • Micrornas in biological processes and carcinogenesis
    • Osada, H., and Takahashi, T. (2007) MicroRNAs in biological processes and carcinogenesis. Carcinogenesis. 28, 2-12
    • (2007) Carcinogenesis. , vol.28 , pp. 2-12
    • Osada, H.1    Takahashi, T.2
  • 23
    • 0036342719 scopus 로고    scopus 로고
    • Tissue microarrays: A new approach for quality control in immunohistochemistry
    • Packeisen, J., Buerger, H., Krech, R., and Boecker, W. (2002) Tissue microarrays: a new approach for quality control in immunohistochemistry. J. Clin. Pathol. 55, 613-615
    • (2002) J. Clin. Pathol. , vol.55 , pp. 613-615
    • Packeisen, J.1    Buerger, H.2    Krech, R.3    Boecker, W.4
  • 25
    • 61449172037 scopus 로고    scopus 로고
    • Systematic and integrative analysis of large gene lists using david bioinformatics resources
    • Huang da, W., Sherman, B. T., and Lempicki, R. A. (2009) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat. Protoc. 4, 44-57
    • (2009) Nat. Protoc. , vol.4 , pp. 44-57
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 26
    • 58549112996 scopus 로고    scopus 로고
    • Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
    • Huang da, W., Sherman, B. T., and Lempicki, R. A. (2009) Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res. 37, 1-13
    • (2009) Nucleic Acids Res. , vol.37 , pp. 1-13
    • Huang Da, W.1    Sherman, B.T.2    Lempicki, R.A.3
  • 27
    • 34248644013 scopus 로고    scopus 로고
    • Establishment and characterization of a high metastatic potential in the peritoneum for human gastric cancer by orthotopic tumor cell implantation
    • Bai, F., Guo, X., Yang, L., Wang, J., Shi, Y., Zhang, F., Zhai, H., Lu, Y., Xie, H., Wu, K., and Fan, D. (2007) Establishment and characterization of a high metastatic potential in the peritoneum for human gastric cancer by orthotopic tumor cell implantation. Dig. Dis. Sci. 52, 1571-1578
    • (2007) Dig. Dis. Sci. , vol.52 , pp. 1571-1578
    • Bai, F.1    Guo, X.2    Yang, L.3    Wang, J.4    Shi, Y.5    Zhang, F.6    Zhai, H.7    Lu, Y.8    Xie, H.9    Wu, K.10    Fan, D.11
  • 29
    • 84875222626 scopus 로고    scopus 로고
    • Microrna-7 functions as an anti-metastatic microrna in gastric cancer by targeting insulin-like growth factor-1 receptor
    • Zhao, X., Dou, W., He, L., Liang, S., Tie, J., Liu, C., Li, T., Lu, Y., Mo, P., Shi, Y., Wu, K., Nie, Y., and Fan, D. (2012) MicroRNA-7 functions as an anti-metastatic microRNA in gastric cancer by targeting insulin-like growth factor-1 receptor. Oncogene 32, 1363-1372
    • (2012) Oncogene , vol.32 , pp. 1363-1372
    • Zhao, X.1    Dou, W.2    He, L.3    Liang, S.4    Tie, J.5    Liu, C.6    Li, T.7    Lu, Y.8    Mo, P.9    Shi, Y.10    Wu, K.11    Nie, Y.12    Fan, D.13
  • 30
    • 79960431402 scopus 로고    scopus 로고
    • Microrna-372 is down-regulated and targets cyclin-dependent kinase 2 (cdk2) and cyclin a1 in human cervical cancer, which may contribute to tumorigenesis
    • Tian, R. Q., Wang, X. H., Hou, L. J., Jia, W. H., Yang, Q., Li, Y. X., Liu, M., Li, X., and Tang, H. (2011) MicroRNA-372 is down-regulated and targets cyclin-dependent kinase 2 (CDK2) and cyclin A1 in human cervical cancer, which may contribute to tumorigenesis. J. Biol. Chem. 286, 25556-25563
    • (2011) J. Biol. Chem. , Issue.286 , pp. 25556-25563
    • Tian, R.Q.1    Wang, X.H.2    Hou, L.J.3    Jia, W.H.4    Yang, Q.5    Li, Y.X.6    Liu, M.7    Li, X.8    Tang, H.9
  • 32
    • 79960336510 scopus 로고    scopus 로고
    • Clinical significance of mir-146a in gastric cancer cases
    • Kogo, R., Mimori, K., Tanaka, F., Komune, S., and Mori, M. (2011) Clinical significance of miR-146a in gastric cancer cases. Clin. Cancer Res. 17, 4277-4284
    • (2011) Clin. Cancer Res. , Issue.17 , pp. 4277-4284
    • Kogo, R.1    Mimori, K.2    Tanaka, F.3    Komune, S.4    Mori, M.5
  • 35
    • 79960908459 scopus 로고    scopus 로고
    • Runx3 suppresses gastric cancer metastasis through inactivation of mmp9 by upregulation of timp-1
    • Chen, Y., Wei, X., Guo, C., Jin, H., Han, Z., Han, Y., Qiao, T., Wu, K., and Fan, D. (2011) Runx3 suppresses gastric cancer metastasis through inactivation of MMP9 by upregulation of TIMP-1. Int. J. Cancer 129, 1586-1598
    • (2011) Int. J. Cancer , vol.129 , pp. 1586-1598
    • Chen, Y.1    Wei, X.2    Guo, C.3    Jin, H.4    Han, Z.5    Han, Y.6    Qiao, T.7    Wu, K.8    Fan, D.9
  • 41
    • 77954234485 scopus 로고    scopus 로고
    • Down-regulated microrna-152 induces aberrant dna methylation in hepatitis b virus-related hepatocellular carcinoma by targeting dna methyltransferase 1
    • Huang, J., Wang, Y., Guo, Y., and Sun, S. (2010) Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1. Hepatology 52, 60-70
    • (2010) Hepatology , vol.52 , pp. 60-70
    • Huang, J.1    Wang, Y.2    Guo, Y.3    Sun, S.4
  • 42
    • 79960036643 scopus 로고    scopus 로고
    • Microrna-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting dna methyltransferase 1
    • Wang, H., Wu, J., Meng, X., Ying, X., Zuo, Y., Liu, R., Pan, Z., Kang, T., and Huang, W. (2011) MicroRNA-342 inhibits colorectal cancer cell proliferation and invasion by directly targeting DNA methyltransferase 1. Carcinogenesis 32, 1033-1042
    • (2011) Carcinogenesis , vol.32 , pp. 1033-1042
    • Wang, H.1    Wu, J.2    Meng, X.3    Ying, X.4    Zuo, Y.5    Liu, R.6    Pan, Z.7    Kang, T.8    Huang, W.9
  • 44
    • 79960434259 scopus 로고    scopus 로고
    • Microrna-146a downregulates nfkappab activity via targeting traf6 and functions as a tumor suppressor having strong prognostic implications in nk/t cell lymphoma
    • Paik, J. H., Jang, J. Y., Jeon, Y. K., Kim, W. Y., Kim, T. M., Heo, D. S., and Kim, C. W. (2011) MicroRNA-146a downregulates NFkappaB activity via targeting TRAF6 and functions as a tumor suppressor having strong prognostic implications in NK/T cell lymphoma. Clin. Cancer Res. 17, 4761-4771
    • (2011) Clin. Cancer Res. , Issue.17 , pp. 4761-4771
    • Paik, J.H.1    Jang, J.Y.2    Jeon, Y.K.3    Kim, W.Y.4    Kim, T.M.5    Heo, D.S.6    Kim, C.W.7
  • 45
    • 79960613869 scopus 로고    scopus 로고
    • Overexpression of the lung cancer-prognostic mir-146b micrornas has a minimal and negative effect on the malignant phenotype of a549 lung cancer cells
    • Patnaik, S. K., Kannisto, E., Mallick, R., and Yendamuri, S. (2011) Overexpression of the lung cancer-prognostic miR-146b microRNAs has a minimal and negative effect on the malignant phenotype of A549 lung cancer cells. PloS One 6, e22379
    • (2011) PloS One , vol.6
    • Patnaik, S.K.1    Kannisto, E.2    Mallick, R.3    Yendamuri, S.4
  • 47
    • 84862908996 scopus 로고    scopus 로고
    • Increased mir-146a in gastric cancer directly targets smad4 and is involved in modulating cell proliferation and apoptosis
    • Xiao, B., Zhu, E. D., Li, N., Lu, D. S., Li, W., Li, B. S., Zhao, Y. L., Mao, X. H., Guo, G., Yu, P. W., and Zou, Q. M. (2012) Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis. Oncol. Rep. 27, 559-566
    • (2012) Oncol. Rep. , Issue.27 , pp. 559-566
    • Xiao, B.1    Zhu, E.D.2    Li, N.3    Lu, D.S.4    Li, W.5    Li, B.S.6    Zhao, Y.L.7    Mao, X.H.8    Guo, G.9    Yu, P.W.10    Zou, Q.M.11
  • 48
    • 84865183734 scopus 로고    scopus 로고
    • Microrna-146a targets the l1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer
    • Hou, Z., Yin, H., Chen, C., Dai, X., Li, X., Liu, B., and Fang, X. (2012) microRNA-146a targets the L1 cell adhesion molecule and suppresses the metastatic potential of gastric cancer. Mol. Med. Rep. 6, 501-506
    • (2012) Mol. Med. Rep. , Issue.6 , pp. 501-506
    • Hou, Z.1    Yin, H.2    Chen, C.3    Dai, X.4    Li, X.5    Liu, B.6    Fang, X.7
  • 49
    • 63049090100 scopus 로고    scopus 로고
    • Metastasis: From dissemination to organ-specific colonization
    • Nguyen, D. X., Bos, P. D., and Massague, J. (2009) Metastasis: from dissemination to organ-specific colonization. Nat. Rev. Cancer 9, 274-284
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 274-284
    • Nguyen, D.X.1    Bos, P.D.2    Massague, J.3
  • 50
    • 33746851956 scopus 로고    scopus 로고
    • Tumor metastasis: Mechanistic insights and clinical challenges
    • Steeg, P. S. (2006) Tumor metastasis: mechanistic insights and clinical challenges. Nat. Med. 12, 895-904
    • (2006) Nat. Med. , vol.12
    • Steeg, P.S.1
  • 52
    • 79959812634 scopus 로고    scopus 로고
    • Cdh4 as a novel putative tumor suppressor gene epigenetically silenced by promoter hypermethylation in nasopharyngeal carcinoma
    • Du, C., Huang, T., Sun, D., Mo, Y., Feng, H., Zhou, X., Xiao, X., Yu, N., Hou, B., Huang, G., Ernberg, I., and Zhang, Z. (2011) CDH4 as a novel putative tumor suppressor gene epigenetically silenced by promoter hypermethylation in nasopharyngeal carcinoma. Cancer Lett. 309, 54-61
    • (2011) Cancer Lett. , Issue.309 , pp. 54-61
    • Du, C.1    Huang, T.2    Sun, D.3    Mo, Y.4    Feng, H.5    Zhou, X.6    Xiao, X.7    Yu, N.8    Hou, B.9    Huang, G.10    Ernberg, I.11    Zhang, Z.12
  • 53
    • 84867115486 scopus 로고    scopus 로고
    • Microenvironmental regulation of epithelial-mesenchymal transitions in cancer
    • Gao, D., Vahdat, L. T., Wong, S., Chang, J. C., and Mittal, V. (2012) Microenvironmental regulation of epithelial-mesenchymal transitions in cancer. Cancer Res. 72, 4883-4889
    • (2012) Cancer Res. , Issue.72 , pp. 4883-4889
    • Gao, D.1    Vahdat, L.T.2    Wong, S.3    Chang, J.C.4    Mittal, V.5
  • 55
    • 84868193092 scopus 로고    scopus 로고
    • Stepwise cumulation of runx3 methylation mediated by helicobacter pylori infection contributes to gastric carcinoma progression
    • Lu, X. X., Yu, J. L., Ying, L. S., Han, J., Wang, S., Yu, Q. M., Wang, X. B., Fang, X. H., and Ling, Z. Q. (2012) Stepwise cumulation of RUNX3 methylation mediated by Helicobacter pylori infection contributes to gastric carcinoma progression. Cancer 118, 5507-5517
    • (2012) Cancer , vol.118 , pp. 5507-5517
    • Lu, X.X.1    Yu, J.L.2    Ying, L.S.3    Han, J.4    Wang, S.5    Yu, Q.M.6    Wang, X.B.7    Fang, X.H.8    Ling, Z.Q.9


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