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Volumn 4, Issue 3, 2012, Pages 279-294

Epigenetic mechanisms in gastric cancer

Author keywords

chromatin remodeling complex; DNA methylation; epigenetics; gastric cancer; histone acetylation; histone methylation; hypermethylation; miRNA; phosphorylation

Indexed keywords

AZACITIDINE; BIOLOGICAL MARKER; BRG1 PROTEIN; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; HISTONE ACETYLTRANSFERASE; HISTONE ACETYLTRANSFERASE PCAF; HISTONE DEACETYLASE 1; HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 3; HISTONE DEACETYLASE 8; HISTONE H3; MICRORNA; MICRORNA 101; MICRORNA 10B; MICRORNA 16; MICRORNA 182; MICRORNA 192; MICRORNA 200; MICRORNA 29A; MICRORNA 34B; MICRORNA 375; MICRORNA 9; PROTEIN HBO1; PROTEIN SWI; PROTEIN TIP60; SIRTUIN 1; TRANSCRIPTION FACTOR SNF; TRICHOSTATIN A; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 84862246467     PISSN: 17501911     EISSN: 1750192X     Source Type: Journal    
DOI: 10.2217/epi.12.22     Document Type: Review
Times cited : (107)

References (151)
  • 4
  • 5
    • 12644292106 scopus 로고
    • The two histological main types of gastric carcinoma: Diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification
    • Laurén P. The two histological main types of gastric carcinoma: diffuse and so-called intestinal-type carcinoma. An attempt at a histo-clinical classification. Acta. Pathol. Microbiol. Scand. 64, 31-49 (1965).
    • (1965) Acta. Pathol. Microbiol. Scand. , vol.64 , pp. 31-49
    • Laurén, P.1
  • 6
    • 0036313986 scopus 로고    scopus 로고
    • Profiling and selection of genes differentially expressed in the pylorus of rat strains with different proliferative responses and stomach cancer susceptibility
    • Yamashita S, Wakazono K, Sugimura T, Ushijima T. Profiling and selection of genes differentially expressed in the pylorus of rat strains with different proliferative responses and stomach cancer susceptibility. Carcinogenesis 23(6), 923-928 (2002).
    • (2002) Carcinogenesis , vol.23 , Issue.6 , pp. 923-928
    • Yamashita, S.1    Wakazono, K.2    Sugimura, T.3    Ushijima, T.4
  • 8
    • 77952982353 scopus 로고    scopus 로고
    • The role of surgery in the treatment of gastric cancer
    • Shi Y, Zhou Y. The role of surgery in the treatment of gastric cancer. J. Surg. Oncol. 101(8), 687-692 (2010).
    • (2010) J. Surg. Oncol. , vol.101 , Issue.8 , pp. 687-692
    • Shi, Y.1    Zhou, Y.2
  • 9
    • 63649142902 scopus 로고    scopus 로고
    • Genética e câncer gástrico
    • Linhares E, Laércio L, Takeshi S (Eds). Tecmed, São Paulo, Brazil
    • Assumpção PP, Burbano RR. Genética e câncer gástrico. In: Atualização em Câncer-Gástrico. Linhares E, Laércio L, Takeshi S (Eds). Tecmed, São Paulo, Brazil, 95-106 (2005).
    • (2005) Atualização Em Câncer-Gástrico , pp. 95-106
    • Assumpção, P.P.1    Burbano, R.R.2
  • 11
    • 68349117100 scopus 로고    scopus 로고
    • Interrelationship between TP53 gene deletion, protein expression and chromosome 17 aneusomy in gastric adenocarcinoma
    • Khayat AS, Guimaraes AC, Calcagno DQ et al. Interrelationship between TP53 gene deletion, protein expression and chromosome 17 aneusomy in gastric adenocarcinoma. BMC Gastroenterol. 9, 55 (2009).
    • (2009) BMC Gastroenterol. , vol.9 , pp. 55
    • Khayat, A.S.1    Guimaraes, A.C.2    Calcagno, D.Q.3
  • 12
    • 27944471750 scopus 로고    scopus 로고
    • Aneuploidy of chromosome 8 and C-MYC amplification in individuals from northern Brazil with gastric adenocarcinoma
    • Calcagno DQ, Leal MF, Taken SS et al. Aneuploidy of chromosome 8 and C-MYC amplification in individuals from northern Brazil with gastric adenocarcinoma. Anticancer Res. 25(6B), 4069-4074 (2005).
    • (2005) Anticancer Res. , vol.25 , Issue.6 , pp. 4069-4074
    • Calcagno, D.Q.1    Leal, M.F.2    Taken, S.S.3
  • 13
    • 33746761107 scopus 로고    scopus 로고
    • C-MYC locus amplification as metastasis predictor in intestinal-type gastric adenocarcinomas: CGH study in Brazil
    • Burbano RR, Assumpcao PP, Leal MF et al. C-MYC locus amplification as metastasis predictor in intestinal-type gastric adenocarcinomas: CGH study in Brazil. Anticancer Res. 26(4B), 2909-2914 (2006).
    • (2006) Anticancer Res. , vol.26 , Issue.4 , pp. 2909-2914
    • Burbano, R.R.1    Assumpcao, P.P.2    Leal, M.F.3
  • 14
    • 33746255960 scopus 로고    scopus 로고
    • Numerical aberrations of chromosome 8 detected by conventional cytogenetics and fluorescence in situ hybridization in individuals from northern Brazil with gastric adenocarcinoma
    • Assumpcao PP, Ishak G, Chen ES et al. Numerical aberrations of chromosome 8 detected by conventional cytogenetics and fluorescence in situ hybridization in individuals from northern Brazil with gastric adenocarcinoma. Cancer Genet. Cytogenet. 169(1), 45-49 (2006).
    • (2006) Cancer Genet. Cytogenet. , vol.169 , Issue.1 , pp. 45-49
    • Assumpcao, P.P.1    Ishak, G.2    Chen, E.S.3
  • 15
    • 69249161792 scopus 로고    scopus 로고
    • MYC insertions in diffuse-type gastric adenocarcinoma
    • Calcagno DQ, Guimaraes AC, Leal MF et al. MYC insertions in diffuse-type gastric adenocarcinoma. Anticancer Res. 29(7), 2479-2483 (2009).
    • (2009) Anticancer Res. , vol.29 , Issue.7 , pp. 2479-2483
    • Calcagno, D.Q.1    Guimaraes, A.C.2    Leal, M.F.3
  • 16
    • 80054895610 scopus 로고    scopus 로고
    • Survivin -31C/G polymorphism and gastric cancer risk in a Brazilian population
    • Borges Bdo N, Burbano RR, Harada ML. Survivin -31C/G polymorphism and gastric cancer risk in a Brazilian population. Clin. Exp. Med. 11(3), 189-193 (2011).
    • (2011) Clin. Exp. Med. , vol.11 , Issue.3 , pp. 189-193
    • Borges Bdo, N.1    Burbano, R.R.2    Harada, M.L.3
  • 18
    • 29144478593 scopus 로고    scopus 로고
    • Polymorphisms of the TP53 codon 72 and WRN codon 1367 in individuals from northern Brazil with gastric adenocarcinoma
    • Khayat AS, Lobo Gatti L, Moura Lima E et al. Polymorphisms of the TP53 codon 72 and WRN codon 1367 in individuals from northern Brazil with gastric adenocarcinoma. Clin. Exp. Med. 5(4), 161-168 (2005).
    • (2005) Clin. Exp. Med. , vol.5 , Issue.4 , pp. 161-168
    • Khayat, A.S.1    Lobo Gatti, L.2    Moura Lima, E.3
  • 19
    • 29244469466 scopus 로고    scopus 로고
    • The epigenetic progenitor origin of human cancer
    • Feinberg AP, Ohlsson R, Henikoff S. The epigenetic progenitor origin of human cancer. Nat. Rev. Genet. 7(1), 21-33 (2006).
    • (2006) Nat. Rev. Genet. , vol.7 , Issue.1 , pp. 21-33
    • Feinberg, A.P.1    Ohlsson, R.2    Henikoff, S.3
  • 20
    • 84862259429 scopus 로고    scopus 로고
    • The epigenotype. Endeavour 1, 18-20 (1942). and stomach cancer susceptibility
    • Waddington CH. The epigenotype. Endeavour 1, 18-20 (1942). and stomach cancer susceptibility. Carcinogenesis 23(6), 923-928 (2002).
    • (2002) Carcinogenesis , vol.23 , Issue.6 , pp. 923-928
    • Waddington, C.H.1
  • 21
    • 74049141478 scopus 로고    scopus 로고
    • Epigenetics in cancer
    • A very comprehensive review about overall epigenetic mechanisms in normal and cancer cells
    • Sharma S, Kelly TK, Jones PA. Epigenetics in cancer. Carcinogenesis 31(1), 27-36 (2010). A very comprehensive review about overall epigenetic mechanisms in normal and cancer cells.
    • (2010) Carcinogenesis , vol.31 , Issue.1 , pp. 27-36
    • Sharma, S.1    Kelly, T.K.2    Jones, P.A.3
  • 23
    • 77957970301 scopus 로고    scopus 로고
    • Epigenetic modifications and human disease
    • Excellent and well-written review about all types of epigenetic modifications and the abnormal epimarkers in disease, such as cancer and neurodevelopmental, neurodegenerative and autoimmune disorders
    • Portela A, Esteller M. Epigenetic modifications and human disease. Nat. Biotechnol. 28(10), 1057-1068 (2010). Excellent and well-written review about all types of epigenetic modifications and the abnormal epimarkers in disease, such as cancer and neurodevelopmental, neurodegenerative and autoimmune disorders.
    • (2010) Nat. Biotechnol. , vol.28 , Issue.10 , pp. 1057-1068
    • Portela, A.1    Esteller, M.2
  • 24
    • 79956330964 scopus 로고    scopus 로고
    • CpG islands and the regulation of transcription
    • Deaton AM, Bird A. CpG islands and the regulation of transcription. Genes Dev. 25(10), 1010-1022 (2011).
    • (2011) Genes Dev. , vol.25 , Issue.10 , pp. 1010-1022
    • Deaton, A.M.1    Bird, A.2
  • 25
    • 78649383152 scopus 로고    scopus 로고
    • Cancer epigenetics
    • Clinical applications of epigenetic tumor markers drugs and therapy in cancer
    • Taby R, Issa JP. Cancer epigenetics. CA Cancer J. Clin. 60(6), 376-392 (2010). Clinical applications of epigenetic tumor markers drugs and therapy in cancer.
    • (2010) CA Cancer J. Clin. , vol.60 , Issue.6 , pp. 376-392
    • Taby, R.1    Issa, J.P.2
  • 26
    • 77649110590 scopus 로고    scopus 로고
    • A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma
    • Fan H, Liu D, Qiu X et al. A functional polymorphism in the DNA methyltransferase-3A promoter modifies the susceptibility in gastric cancer but not in esophageal carcinoma. BMC Med. 8, 12 (2010).
    • (2010) BMC Med. , vol.8 , pp. 12
    • Fan, H.1    Liu, D.2    Qiu, X.3
  • 27
    • 77950347697 scopus 로고    scopus 로고
    • DNMT3B promoter polymorphism and risk of gastric cancer
    • Hu J, Fan H, Liu D, Zhang S, Zhang F, Xu H. DNMT3B promoter polymorphism and risk of gastric cancer. Dig. Dis. Sci. 55(4), 1011-1016 (2010).
    • (2010) Dig. Dis. Sci. , vol.55 , Issue.4 , pp. 1011-1016
    • Hu, J.1    Fan, H.2    Liu, D.3    Zhang, S.4    Zhang, F.5    Xu, H.6
  • 28
    • 80053097241 scopus 로고    scopus 로고
    • Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer
    • Yang J, Wei X, Wu Q et al. Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer. Mol. Med. Report 4(6), 1139-1143 (2011).
    • (2011) Mol. Med. Report , vol.4 , Issue.6 , pp. 1139-1143
    • Yang, J.1    Wei, X.2    Wu, Q.3
  • 29
    • 78650990943 scopus 로고    scopus 로고
    • Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer
    • Mutze K, Langer R, Becker K et al. Histone deacetylase (HDAC) 1 and 2 expression and chemotherapy in gastric cancer. Ann. Surg. Oncol. 17(12), 3336-3343 (2010).
    • (2010) Ann. Surg. Oncol. , vol.17 , Issue.12 , pp. 3336-3343
    • Mutze, K.1    Langer, R.2    Becker, K.3
  • 30
    • 0035863455 scopus 로고    scopus 로고
    • DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers
    • Kanai Y, Ushijima S, Kondo Y, Nakanishi Y, Hirohashi S. DNA methyltransferase expression and DNA methylation of CPG islands and peri-centromeric satellite regions in human colorectal and stomach cancers. Int. J. Cancer 91(2), 205-212 (2001).
    • (2001) Int. J. Cancer , vol.91 , Issue.2 , pp. 205-212
    • Kanai, Y.1    Ushijima, S.2    Kondo, Y.3    Nakanishi, Y.4    Hirohashi, S.5
  • 31
    • 79955392330 scopus 로고    scopus 로고
    • Helicobacter pylori infection promotes methylation of WWOX gene in human gastric cancer
    • Yan J, Zhang M, Zhang J, Chen X, Zhang X. Helicobacter pylori infection promotes methylation of WWOX gene in human gastric cancer. Biochem. Biophys. Res. Commun. 408(1), 99-102 (2011).
    • (2011) Biochem. Biophys. Res. Commun. , vol.408 , Issue.1 , pp. 99-102
    • Yan, J.1    Zhang, M.2    Zhang, J.3    Chen, X.4    Zhang, X.5
  • 32
    • 0035461346 scopus 로고    scopus 로고
    • DNA methylation status of hMLH1, p16(INK4a), and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas
    • Oue N, Kuraoka K, Kuniyasu H et al. DNA methylation status of hMLH1, p16(INK4a), and CDH1 is not associated with mRNA expression levels of DNA methyltransferase and DNA demethylase in gastric carcinomas. Oncol. Rep. 8(5), 1085-1089 (2001).
    • (2001) Oncol. Rep. , vol.8 , Issue.5 , pp. 1085-1089
    • Oue, N.1    Kuraoka, K.2    Kuniyasu, H.3
  • 34
    • 80053144962 scopus 로고    scopus 로고
    • A decade of exploring the cancer epigenome - Biological and translational implications
    • Baylin SB, Jones PA. A decade of exploring the cancer epigenome - biological and translational implications. Nat. Rev. Cancer 11(10), 726-734 (2011).
    • (2011) Nat. Rev. Cancer , vol.11 , Issue.10 , pp. 726-734
    • Baylin, S.B.1    Jones, P.A.2
  • 35
    • 77952534140 scopus 로고    scopus 로고
    • Helicobacter pylori infection, oncogenic pathways and epigenetic mechanisms in gastric carcinogenesis
    • Very important to gastric carcinogenesis, this review provides a Helicobacter pylori overview about pathogenicity mechanisms and pathways via epigenetic alterations
    • Ding SZ, Goldberg JB, Hatakeyama M. Helicobacter pylori infection, oncogenic pathways and epigenetic mechanisms in gastric carcinogenesis. Future Oncol. 6(5), 851-862 (2010). Very important to gastric carcinogenesis, this review provides a Helicobacter pylori overview about pathogenicity mechanisms and pathways via epigenetic alterations.
    • (2010) Future Oncol. , vol.6 , Issue.5 , pp. 851-862
    • Ding, S.Z.1    Goldberg, J.B.2    Hatakeyama, M.3
  • 36
    • 84874596753 scopus 로고    scopus 로고
    • DNA and histone methylation in gastric carcinogenesis
    • In Press. A recent review that provides extensive information about DNA and histone methylation machinery and alterations in gastric cancer
    • Calcagno DQ, Gigek CO, Chen ES, Burbano RR, Smith MAC. DNA and histone methylation in gastric carcinogenesis. World J. Gastroenterol. (2012) (In Press). A recent review that provides extensive information about DNA and histone methylation machinery and alterations in gastric cancer
    • (2012) World J. Gastroenterol.
    • Calcagno, D.Q.1    Gigek, C.O.2    Chen, E.S.3    Burbano, R.R.4    Smith, M.A.C.5
  • 37
    • 0037068312 scopus 로고    scopus 로고
    • CpG island hypermethylation and tumor suppressor genes: A booming present, a brighter future
    • Esteller M. CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future. Oncogene 21(35), 5427-5440 (2002).
    • (2002) Oncogene , vol.21 , Issue.35 , pp. 5427-5440
    • Esteller, M.1
  • 38
    • 84872203706 scopus 로고    scopus 로고
    • Recent progress in the study of methylated tumor suppressor genes in gastric cancer
    • doi:10.5732/cjc.011.10175 Epub ahead of print. A detailed description of several hypermethylated tumor-suppressor genes previously described in gastric cancer
    • Hu XT, He C. Recent progress in the study of methylated tumor suppressor genes in gastric cancer. Chin. J. Cancer doi:10.5732/cjc.011.10175 (2011) (Epub ahead of print). A detailed description of several hypermethylated tumor-suppressor genes previously described in gastric cancer.
    • (2011) Chin. J. Cancer
    • Hu, X.T.1    He, C.2
  • 39
    • 84862777258 scopus 로고    scopus 로고
    • Prediction of the risk for gastric cancer using candidate methylation markers in the non-neoplastic gastric mucosae
    • Shin CM, Kim N, Park JH et al. Prediction of the risk for gastric cancer using candidate methylation markers in the non-neoplastic gastric mucosae. J. Pathol. 226(4), 654-665 (2012).
    • (2012) J. Pathol. , vol.226 , Issue.4 , pp. 654-665
    • Shin, C.M.1    Kim, N.2    Park, J.H.3
  • 40
    • 64249160168 scopus 로고    scopus 로고
    • DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: Its possible involvement in the formation of epigenetic field defect
    • Ando T, Yoshida T, Enomoto S et al. DNA methylation of microRNA genes in gastric mucosae of gastric cancer patients: its possible involvement in the formation of epigenetic field defect. Int. J. Cancer 124(10), 2367-2374 (2009).
    • (2009) Int. J. Cancer , vol.124 , Issue.10 , pp. 2367-2374
    • Ando, T.1    Yoshida, T.2    Enomoto, S.3
  • 41
    • 77953082600 scopus 로고    scopus 로고
    • Insulin-like growth factor binding protein-3 gene methylation and protein expression in gastric adenocarcinoma
    • Gigek CO, Leal MF, Lisboa LC et al. Insulin-like growth factor binding protein-3 gene methylation and protein expression in gastric adenocarcinoma. Growth Horm. IGF Res. 20(3), 234-238 (2010).
    • (2010) Growth Horm. IGF Res. , vol.20 , Issue.3 , pp. 234-238
    • Gigek, C.O.1    Leal, M.F.2    Lisboa, L.C.3
  • 42
    • 34250648916 scopus 로고    scopus 로고
    • Promoter hypermethylation of CDH1, FHIT, TAP and PLAGL1 in gastric adenocarcinoma in individuals from northern Brazil
    • Leal MF, Lima EM, Silva PN et al. Promoter hypermethylation of CDH1, FHIT, TAP and PLAGL1 in gastric adenocarcinoma in individuals from northern Brazil. World J. Gastroenterol. 13(18), 2568-2574 (2007).
    • (2007) World J. Gastroenterol. , vol.13 , Issue.18 , pp. 2568-2574
    • Leal, M.F.1    Lima, E.M.2    Silva, P.N.3
  • 43
    • 70349096840 scopus 로고    scopus 로고
    • Helicobacter pylori infection and family history of gastric cancer decrease expression of FHIT tumor suppressor gene in gastric mucosa of dyspeptic patients
    • Stec-Michalska K, Peczek L, Michalski B, Wisniewska-Jarosinska M, Krakowiak A, Nawrot B. Helicobacter pylori infection and family history of gastric cancer decrease expression of FHIT tumor suppressor gene in gastric mucosa of dyspeptic patients. Helicobacter 14(5), 126-134 (2009).
    • (2009) Helicobacter , vol.14 , Issue.5 , pp. 126-134
    • Stec-Michalska, K.1    Peczek, L.2    Michalski, B.3    Wisniewska-Jarosinska, M.4    Krakowiak, A.5    Nawrot, B.6
  • 44
    • 77955068277 scopus 로고    scopus 로고
    • Promoter polymorphisms and methylation of E-cadherin (CDH1) and KIT in gastric cancer patients from northern Brazil
    • Borges Bdo N, Santos Eda S, Bastos CE et al. Promoter polymorphisms and methylation of E-cadherin (CDH1) and KIT in gastric cancer patients from northern Brazil. Anticancer Res. 30(6), 2225-2233 (2010).
    • (2010) Anticancer Res. , vol.30 , Issue.6 , pp. 2225-2233
    • Borges Bdo, N.1    Santos Eda, S.2    Bastos, C.E.3
  • 45
    • 59149084538 scopus 로고    scopus 로고
    • The human colon cancer methylome shows similar hypo- And hypermethylation at conserved tissue-specific CpG island shores
    • Irizarry RA, Ladd-Acosta C, Wen B et al. The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores. Nat. Genet. 41(2), 178-186 (2009).
    • (2009) Nat. Genet. , vol.41 , Issue.2 , pp. 178-186
    • Irizarry, R.A.1    Ladd-Acosta, C.2    Wen, B.3
  • 46
    • 78049419464 scopus 로고    scopus 로고
    • Orphan CpG islands identify numerous conserved promoters in the mammalian genome
    • pii: e1001134
    • Illingworth RS, Gruenewald-Schneider U, Webb S et al. Orphan CpG islands identify numerous conserved promoters in the mammalian genome. PLoS Genet. 6(9), pii: e1001134 (2010).
    • (2010) PLoS Genet. , vol.6 , Issue.9
    • Illingworth, R.S.1    Gruenewald-Schneider, U.2    Webb, S.3
  • 47
    • 72949108868 scopus 로고    scopus 로고
    • hTERT methylation and expression in gastric cancer
    • Gigek CO, Leal MF, Silva PN et al. hTERT methylation and expression in gastric cancer. Biomarkers 14(8), 630-636 (2009).
    • (2009) Biomarkers , vol.14 , Issue.8 , pp. 630-636
    • Gigek, C.O.1    Leal, M.F.2    Silva, P.N.3
  • 48
    • 54749138808 scopus 로고    scopus 로고
    • Methylation status of ANAPC1, CDKN2A and TP53 promoter genes in individuals with gastric cancer
    • Lima EM, Leal MF, Burbano RR et al. Methylation status of ANAPC1, CDKN2A and TP53 promoter genes in individuals with gastric cancer. Braz. J. Med. Biol. Res. 41(6), 539-543 (2008).
    • (2008) Braz. J. Med. Biol. Res. , vol.41 , Issue.6 , pp. 539-543
    • Lima, E.M.1    Leal, M.F.2    Burbano, R.R.3
  • 49
    • 77949879997 scopus 로고    scopus 로고
    • CDKN2A promoter methylation is related to the tumor location and histological subtype and associated with Helicobacter pylori flaA(+) strains in gastric adenocarcinomas
    • Alves MK, Lima VP, Ferrasi AC, Rodrigues MA, De Moura Campos Pardini MI, Rabenhorst SH. CDKN2A promoter methylation is related to the tumor location and histological subtype and associated with Helicobacter pylori flaA(+) strains in gastric adenocarcinomas. APMIS 118(4), 297-307 (2010).
    • (2010) APMIS , vol.118 , Issue.4 , pp. 297-307
    • Alves, M.K.1    Lima, V.P.2    Ferrasi, A.C.3    Rodrigues, M.A.4    De Moura Campos Pardini, M.I.5    Rabenhorst, S.H.6
  • 50
    • 84862241007 scopus 로고    scopus 로고
    • PDCD4 expression inversely correlated with miR-21 levels in gastric cancers
    • Cao Z, Yoon JH, Nam SW, Lee JY, Park WS. PDCD4 expression inversely correlated with miR-21 levels in gastric cancers. J. Cancer Res. Clin. Oncol. 138(4), 611-619 (2012).
    • (2012) J. Cancer Res. Clin. Oncol. , vol.138 , Issue.4 , pp. 611-619
    • Cao, Z.1    Yoon, J.H.2    Nam, S.W.3    Lee, J.Y.4    Park, W.S.5
  • 51
    • 81555214109 scopus 로고    scopus 로고
    • Hypermethylated DNA as potential biomarkers for gastric cancer diagnosis
    • Zheng Y, Chen L, Li J et al. Hypermethylated DNA as potential biomarkers for gastric cancer diagnosis. Clin. Biochem. 44(17-18), 1405-1411 (2011).
    • (2011) Clin. Biochem. , vol.44 , Issue.17-18 , pp. 1405-1411
    • Zheng, Y.1    Chen, L.2    Li, J.3
  • 52
    • 64049109677 scopus 로고    scopus 로고
    • Identification of genes epigenetically silenced by CpG methylation in human gastric carcinoma
    • Jee CD, Kim MA, Jung EJ, Kim J, Kim WH. Identification of genes epigenetically silenced by CpG methylation in human gastric carcinoma. Eur. J. Cancer 45(7), 1282-1293 (2009).
    • (2009) Eur. J. Cancer , vol.45 , Issue.7 , pp. 1282-1293
    • Jee, C.D.1    Kim, M.A.2    Jung, E.J.3    Kim, J.4    Kim, W.H.5
  • 53
    • 77950355079 scopus 로고    scopus 로고
    • Upregulation and CpG island hypomethylation of the TRF2 gene in human gastric cancer
    • Dong W, Wang L, Chen X, Sun P, Wu Y. Upregulation and CpG island hypomethylation of the TRF2 gene in human gastric cancer. Dig. Dis. Sci. 55(4), 997-1003 (2010).
    • (2010) Dig. Dis. Sci. , vol.55 , Issue.4 , pp. 997-1003
    • Dong, W.1    Wang, L.2    Chen, X.3    Sun, P.4    Wu, Y.5
  • 54
    • 80053994167 scopus 로고    scopus 로고
    • Spreading of Alu methylation to the promoter of the MLH1 gene in gastrointestinal cancer
    • Wang X, Fan J, Liu D, Fu S, Ingvarsson S, Chen H. Spreading of Alu methylation to the promoter of the MLH1 gene in gastrointestinal cancer. PLoS ONE 6(10), e25913 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.10
    • Wang, X.1    Fan, J.2    Liu, D.3    Fu, S.4    Ingvarsson, S.5    Chen, H.6
  • 55
    • 44849129676 scopus 로고    scopus 로고
    • P16 promoter hypermethylation: A useful serum marker for early detection of gastric cancer
    • Abbaszadegan MR, Moaven O, Sima HR et al. p16 promoter hypermethylation: a useful serum marker for early detection of gastric cancer. World J. Gastroenterol. 14(13), 2055-2060 (2008).
    • (2008) World J. Gastroenterol. , vol.14 , Issue.13 , pp. 2055-2060
    • Abbaszadegan, M.R.1    Moaven, O.2    Sima, H.R.3
  • 56
    • 34250214872 scopus 로고    scopus 로고
    • Clinical application of methylation specific-polymerase chain reaction in serum of patients with gastric cancer
    • Ikoma H, Ichikawa D, Daito I et al. Clinical application of methylation specific-polymerase chain reaction in serum of patients with gastric cancer. Hepatogastroenterology 54(75), 946-950 (2007).
    • (2007) Hepatogastroenterology , vol.54 , Issue.75 , pp. 946-950
    • Ikoma, H.1    Ichikawa, D.2    Daito, I.3
  • 57
    • 48049106902 scopus 로고    scopus 로고
    • Detection of RASSF1A promoter hypermethylation in serum from gastric and colorectal adenocarcinoma patients
    • Wang YC, Yu ZH, Liu C et al. Detection of RASSF1A promoter hypermethylation in serum from gastric and colorectal adenocarcinoma patients. World J. Gastroenterol. 14(19), 3074-3080 (2008).
    • (2008) World J. Gastroenterol. , vol.14 , Issue.19 , pp. 3074-3080
    • Wang, Y.C.1    Yu, Z.H.2    Liu, C.3
  • 58
    • 84863230241 scopus 로고    scopus 로고
    • Hypermethylated FAM5C and MYLK in serum as diagnosis and pre-warning markers for gastric cancer
    • Chen L, Su L, Li J et al. Hypermethylated FAM5C and MYLK in serum as diagnosis and pre-warning markers for gastric cancer. Dis. Markers 32(3), 195-202 (2012).
    • (2012) Dis. Markers , vol.32 , Issue.3 , pp. 195-202
    • Chen, L.1    Su, L.2    Li, J.3
  • 59
    • 83055191339 scopus 로고    scopus 로고
    • Detection of TFPI2 methylation in the serum of gastric cancer patients
    • Hibi K, Goto T, Shirahata A et al. Detection of TFPI2 methylation in the serum of gastric cancer patients. Anticancer Res. 31(11), 3835-3838 (2011).
    • (2011) Anticancer Res. , vol.31 , Issue.11 , pp. 3835-3838
    • Hibi, K.1    Goto, T.2    Shirahata, A.3
  • 60
    • 58149147357 scopus 로고    scopus 로고
    • Reprimo as a potential biomarker for early detection in gastric cancer
    • Bernal C, Aguayo F, Villarroel C et al. Reprimo as a potential biomarker for early detection in gastric cancer. Clin. Cancer Res. 14(19), 6264-6269 (2008).
    • (2008) Clin. Cancer Res. , vol.14 , Issue.19 , pp. 6264-6269
    • Bernal, C.1    Aguayo, F.2    Villarroel, C.3
  • 61
    • 84863230017 scopus 로고    scopus 로고
    • Analysis of the RUNX3 gene methylation in serum DNA from esophagus squamous cell carcinoma, gastric and colorectal adenocarcinoma patients
    • Zheng Y, Zhang Y, Huang X, Chen L. Analysis of the RUNX3 gene methylation in serum DNA from esophagus squamous cell carcinoma, gastric and colorectal adenocarcinoma patients. Hepatogastroenterology 58(112), 2007-2011 (2011).
    • (2011) Hepatogastroenterology , vol.58 , Issue.112 , pp. 2007-2011
    • Zheng, Y.1    Zhang, Y.2    Huang, X.3    Chen, L.4
  • 62
    • 73949102040 scopus 로고    scopus 로고
    • The state-of-the-art of chromatin immunoprecipitation
    • Collas P. The state-of-the-art of chromatin immunoprecipitation. Methods Mol. Biol. 567, 1-25 (2009).
    • (2009) Methods Mol. Biol. , vol.567 , pp. 1-25
    • Collas, P.1
  • 63
    • 39549083972 scopus 로고    scopus 로고
    • Chromatin modifications and their mechanism of action
    • Allis CD, Jenuwein T, Reinberg D (Eds). Cold Spring Harbor Laboratory Press, NY, USA
    • Kouzarides T, Berger S. Chromatin modifications and their mechanism of action. In: Epigenetics. Allis CD, Jenuwein T, Reinberg D (Eds). Cold Spring Harbor Laboratory Press, NY, USA 191-209 (2009).
    • (2009) Epigenetics , pp. 191-209
    • Kouzarides, T.1    Berger, S.2
  • 64
    • 84858295994 scopus 로고    scopus 로고
    • Epigenetic modifications in cancer
    • Recent review about miRNA and histone modifications in cancer
    • Kanwal R, Gupta S. Epigenetic modifications in cancer. Clin. Genet. 81(4), 303-311 (2012). Recent review about miRNA and histone modifications in cancer.
    • (2012) Clin. Genet. , vol.81 , Issue.4 , pp. 303-311
    • Kanwal, R.1    Gupta, S.2
  • 65
    • 66149144422 scopus 로고    scopus 로고
    • Inhibition of histone deacetylases
    • Tollefsbol TO (Ed.). Human Press Inc., NJ, USA, Outlines epigenetic basic theories and protocols for researcher.
    • Liu C, Xu D. Inhibition of histone deacetylases. In: Epigenetics Protocol. Tollefsbol TO (Ed.). Human Press Inc., NJ, USA, 87-97 (2010). Outlines epigenetic basic theories and protocols for researchers.
    • (2010) Epigenetics Protocol , pp. 87-97
    • Liu, C.1    Xu, D.2
  • 66
    • 67649305191 scopus 로고    scopus 로고
    • Epigenetics in cancer: Targeting chromatin modifications
    • Ellis L, Atadja PW, Johnstone RW. Epigenetics in cancer: targeting chromatin modifications. Mol. Cancer Ther. 8(6), 1409-1420 (2009).
    • (2009) Mol. Cancer Ther. , vol.8 , Issue.6 , pp. 1409-1420
    • Ellis, L.1    Atadja, P.W.2    Johnstone, R.W.3
  • 67
    • 28044471827 scopus 로고    scopus 로고
    • Acetylation and deacetylation of non-histone proteins
    • Glozak MA, Sengupta N, Zhang X, Seto E. Acetylation and deacetylation of non-histone proteins. Gene 363, 15-23 (2005).
    • (2005) Gene , vol.363 , pp. 15-23
    • Glozak, M.A.1    Sengupta, N.2    Zhang, X.3    Seto, E.4
  • 68
  • 69
    • 33847076849 scopus 로고    scopus 로고
    • Chromatin modifications and their function
    • Kouzarides T. Chromatin modifications and their function. Cell 128(4), 693-705 (2007).
    • (2007) Cell , vol.128 , Issue.4 , pp. 693-705
    • Kouzarides, T.1
  • 72
    • 3142559625 scopus 로고    scopus 로고
    • P300 gene alterations in intestinal and diffuse types of gastric carcinoma
    • Koshiishi N, Chong JM, Fukasawa T et al. p300 gene alterations in intestinal and diffuse types of gastric carcinoma. Gastric Cancer 7(2), 85-90 (2004).
    • (2004) Gastric Cancer , vol.7 , Issue.2 , pp. 85-90
    • Koshiishi, N.1    Chong, J.M.2    Fukasawa, T.3
  • 73
    • 77953590913 scopus 로고    scopus 로고
    • The p300/CBP associated factor: Is frequently downregulated in intestinal-type gastric carcinoma and constitutes a biomarker for clinical outcome
    • Ying MZ, Wang JJ, Li DW et al. The p300/CBP associated factor: is frequently downregulated in intestinal-type gastric carcinoma and constitutes a biomarker for clinical outcome. Cancer Biol. Ther. 9(4), 312-320 (2010).
    • (2010) Cancer Biol. Ther. , vol.9 , Issue.4 , pp. 312-320
    • Ying, M.Z.1    Wang, J.J.2    Li, D.W.3
  • 74
    • 34547897023 scopus 로고    scopus 로고
    • Histone deacetylases and cancer
    • Glozak MA, Seto E. Histone deacetylases and cancer. Oncogene 26(37), 5420-5432 (2007).
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5420-5432
    • Glozak, M.A.1    Seto, E.2
  • 75
    • 33947304344 scopus 로고    scopus 로고
    • Epigenetic events, remodelling enzymes and their relationship to chromatin organization in prostatic intraepithelial neoplasia and prostatic adenocarcinoma
    • Mohamed MA, Greif PA, Diamond J et al. Epigenetic events, remodelling enzymes and their relationship to chromatin organization in prostatic intraepithelial neoplasia and prostatic adenocarcinoma. BJU Int. 99(4), 908-915 (2007).
    • (2007) BJU Int. , vol.99 , Issue.4 , pp. 908-915
    • Mohamed, M.A.1    Greif, P.A.2    Diamond, J.3
  • 76
    • 21044447215 scopus 로고    scopus 로고
    • Increased expression of histone deacetylase 2 is found in human gastric cancer
    • Song J, Noh JH, Lee JH et al. Increased expression of histone deacetylase 2 is found in human gastric cancer. APMIS 113(4), 264-268 (2005).
    • (2005) APMIS , vol.113 , Issue.4 , pp. 264-268
    • Song, J.1    Noh, J.H.2    Lee, J.H.3
  • 77
    • 33645950778 scopus 로고    scopus 로고
    • Histone deacetylase inhibitors: Multifunctional anticancer agents
    • Liu T, Kuljaca S, Tee A, Marshall GM. Histone deacetylase inhibitors: multifunctional anticancer agents. Cancer Treat. Rev. 32(3), 157-165 (2006).
    • (2006) Cancer Treat. Rev. , vol.32 , Issue.3 , pp. 157-165
    • Liu, T.1    Kuljaca, S.2    Tee, A.3    Marshall, G.M.4
  • 79
    • 37249062152 scopus 로고    scopus 로고
    • Histone deacetylase inhibitor trichostatin A induced caspase-independent apoptosis in human gastric cancer cell
    • Wu ZQ, Zhang R, Chao C, Zhang JF, Zhang YQ. Histone deacetylase inhibitor trichostatin A induced caspase-independent apoptosis in human gastric cancer cell. Chin. Med. J. (Engl.) 120(23), 2112-2118 (2007).
    • (2007) Chin. Med. J. (Engl.) , vol.120 , Issue.23 , pp. 2112-2118
    • Wu, Z.Q.1    Zhang, R.2    Chao, C.3    Zhang, J.F.4    Zhang, Y.Q.5
  • 80
    • 55449106873 scopus 로고    scopus 로고
    • Gastric cancer cell lines induced by trichostatin A
    • Zou XM, Li YL, Wang H et al. Gastric cancer cell lines induced by trichostatin A. World J. Gastroenterol. 14(30), 4810-4815 (2008).
    • (2008) World J. Gastroenterol. , vol.14 , Issue.30 , pp. 4810-4815
    • Zou, X.M.1    Li, Y.L.2    Wang, H.3
  • 81
    • 73849085416 scopus 로고    scopus 로고
    • Inhibition of expression of the chromatin remodeling gene, SNF2L, selectively leads to DNA damage, growth inhibition, and cancer cell death
    • Ye Y, Xiao Y, Wang W et al. Inhibition of expression of the chromatin remodeling gene, SNF2L, selectively leads to DNA damage, growth inhibition, and cancer cell death. Mol. Cancer Res. 7(12), 1984-1999 (2009).
    • (2009) Mol. Cancer Res. , vol.7 , Issue.12 , pp. 1984-1999
    • Ye, Y.1    Xiao, Y.2    Wang, W.3
  • 82
    • 79251496644 scopus 로고    scopus 로고
    • SMARCA5 methylation and expression in gastric cancer
    • Gigek CO, Lisboa LC, Leal MF et al. SMARCA5 methylation and expression in gastric cancer. Cancer Invest. 29(2), 162-166 (2011).
    • (2011) Cancer Invest. , vol.29 , Issue.2 , pp. 162-166
    • Gigek, C.O.1    Lisboa, L.C.2    Leal, M.F.3
  • 83
    • 63249112836 scopus 로고    scopus 로고
    • Overexpression of SIRT1 protects pancreatic b-cells against cytokine toxicity by suppressing the nuclear factor-kB signaling pathway
    • Lee JH, Song MY, Song EK et al. Overexpression of SIRT1 protects pancreatic b-cells against cytokine toxicity by suppressing the nuclear factor-kB signaling pathway. Diabetes 58(2), 344-351 (2009).
    • (2009) Diabetes , vol.58 , Issue.2 , pp. 344-351
    • Lee, J.H.1    Song, M.Y.2    Song, E.K.3
  • 84
    • 34547875773 scopus 로고    scopus 로고
    • Sirtuins: Critical regulators at the crossroads between cancer and aging
    • Saunders LR, Verdin E. Sirtuins: critical regulators at the crossroads between cancer and aging. Oncogene 26(37), 5489-5504 (2007).
    • (2007) Oncogene , vol.26 , Issue.37 , pp. 5489-5504
    • Saunders, L.R.1    Verdin, E.2
  • 85
    • 0031706111 scopus 로고    scopus 로고
    • Cloning and mapping of SMARCA5 encoding hSNF2H, a novel human homologue of Drosophila ISWI
    • Aihara T, Miyoshi Y, Koyama K et al. Cloning and mapping of SMARCA5 encoding hSNF2H, a novel human homologue of Drosophila ISWI. Cytogenetics Cell Genetics 81(3-4), 191-193 (1998).
    • (1998) Cytogenetics Cell Genetics , vol.81 , Issue.3-4 , pp. 191-193
    • Aihara, T.1    Miyoshi, Y.2    Koyama, K.3
  • 86
    • 67650348173 scopus 로고    scopus 로고
    • Expression DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma
    • Cha EJ, Noh SJ, Kwon KS et al. Expression DBC1 and SIRT1 is associated with poor prognosis of gastric carcinoma. Clin. Cancer Res. 15(13), 4453-4459 (2009).
    • (2009) Clin. Cancer Res. , vol.15 , Issue.13 , pp. 4453-4459
    • Cha, E.J.1    Noh, S.J.2    Kwon, K.S.3
  • 87
    • 20144388146 scopus 로고    scopus 로고
    • Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer
    • Fraga MF, Ballestar E, Villar-Garea A et al. Loss of acetylation at Lys16 and trimethylation at Lys20 of histone H4 is a common hallmark of human cancer. Nat. Genet. 37(4), 391-400 (2005).
    • (2005) Nat. Genet. , vol.37 , Issue.4 , pp. 391-400
    • Fraga, M.F.1    Ballestar, E.2    Villar-Garea, A.3
  • 88
    • 11144286644 scopus 로고    scopus 로고
    • Histone H3 acetylation is associated with reduced p21 (WAF1/CIP1) expression by gastric carcinoma
    • Mitani Y, Oue N, Hamai Y et al. Histone H3 acetylation is associated with reduced p21 (WAF1/CIP1) expression by gastric carcinoma. J. Pathol. 205(1), 65-73 (2005).
    • (2005) J. Pathol. , vol.205 , Issue.1 , pp. 65-73
    • Mitani, Y.1    Oue, N.2    Hamai, Y.3
  • 89
    • 79959426070 scopus 로고    scopus 로고
    • Human ZNF312b oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer
    • Song IS, Ha GH, Kim JM et al. Human ZNF312b oncogene is regulated by Sp1 binding to its promoter region through DNA demethylation and histone acetylation in gastric cancer. Int. J. Cancer 129(9), 2124-2133 (2011).
    • (2011) Int. J. Cancer , vol.129 , Issue.9 , pp. 2124-2133
    • Song, I.S.1    Ha, G.H.2    Kim, J.M.3
  • 90
    • 77957279576 scopus 로고    scopus 로고
    • S100A6 overexpression is associated with poor prognosis and is epigenetically up-regulated in gastric cancer
    • Wang XH, Zhang LH, Zhong XY et al. S100A6 overexpression is associated with poor prognosis and is epigenetically up-regulated in gastric cancer. Am. J. Pathol. 177(2), 586-597 (2010).
    • (2010) Am. J. Pathol. , vol.177 , Issue.2 , pp. 586-597
    • Wang, X.H.1    Zhang, L.H.2    Zhong, X.Y.3
  • 91
    • 0036738541 scopus 로고    scopus 로고
    • Acetylated histone H4 is reduced in human gastric adenomas and carcinomas
    • Ono S, Oue N, Kuniyasu H et al. Acetylated histone H4 is reduced in human gastric adenomas and carcinomas. J. Exp. Clin. Cancer Res. 21(3), 377-382 (2002).
    • (2002) J. Exp. Clin. Cancer Res. , vol.21 , Issue.3 , pp. 377-382
    • Ono, S.1    Oue, N.2    Kuniyasu, H.3
  • 93
    • 33746324216 scopus 로고    scopus 로고
    • Chromatin modifications by methylation and ubiquitination: Implications in the regulation of gene expression
    • Shilatifard A. Chromatin modifications by methylation and ubiquitination: implications in the regulation of gene expression. Annu. Rev. Biochem. 75, 243-269 (2006).
    • (2006) Annu. Rev. Biochem. , vol.75 , pp. 243-269
    • Shilatifard, A.1
  • 94
    • 0037154972 scopus 로고    scopus 로고
    • Epigenetic codes for heterochromatin formation and silencing: Rounding up the usual suspects
    • Richards EJ, Elgin SC. Epigenetic codes for heterochromatin formation and silencing: rounding up the usual suspects. Cell 108(4), 489-500 (2002).
    • (2002) Cell , vol.108 , Issue.4 , pp. 489-500
    • Richards, E.J.1    Elgin, S.C.2
  • 95
    • 67650264367 scopus 로고    scopus 로고
    • Epigenetic regulation: Methylation of histone and non-histone proteins
    • Lan F, Shi Y. Epigenetic regulation: methylation of histone and non-histone proteins. Sci. China 52(4), 311-322 (2009).
    • (2009) Sci. China , vol.52 , Issue.4 , pp. 311-322
    • Lan, F.1    Shi, Y.2
  • 96
    • 84863011293 scopus 로고    scopus 로고
    • MicroRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN
    • Zhang BG, Li JF, Yu BQ, Zhu ZG, Liu BY, Yan M. microRNA-21 promotes tumor proliferation and invasion in gastric cancer by targeting PTEN. Oncol. Rep. 27(4), 1019-1026 (2012).
    • (2012) Oncol. Rep. , vol.27 , Issue.4 , pp. 1019-1026
    • Zhang, B.G.1    Li, J.F.2    Yu, B.Q.3    Zhu, Z.G.4    Liu, B.Y.5    Yan, M.6
  • 97
    • 46149100720 scopus 로고    scopus 로고
    • The global histone modification pattern correlates with cancer recurrence and overall survival in gastric adenocarcinoma
    • Park YS, Jin MY, Kim YJ, Yook JH, Kim BS, Jang SJ. The global histone modification pattern correlates with cancer recurrence and overall survival in gastric adenocarcinoma. Ann. Surg. Oncol. 15(7), 1968-1976 (2008).
    • (2008) Ann. Surg. Oncol. , vol.15 , Issue.7 , pp. 1968-1976
    • Park, Y.S.1    Jin, M.Y.2    Kim, Y.J.3    Yook, J.H.4    Kim, B.S.5    Jang, S.J.6
  • 98
    • 80155197715 scopus 로고    scopus 로고
    • Claudin-4 overexpression is associated with epigenetic depression in gastric carcinoma
    • Kwon MJ, Kim SH, Jeong HM et al. Claudin-4 overexpression is associated with epigenetic depression in gastric carcinoma. Lab. Invest. 91(11), 1652-1667 (2011).
    • (2011) Lab. Invest. , vol.91 , Issue.11 , pp. 1652-1667
    • Kwon, M.J.1    Kim, S.H.2    Jeong, H.M.3
  • 99
    • 79953028234 scopus 로고    scopus 로고
    • Aberrant up-regulation of LAMB3 and LAMC2 by promoter demethylation in gastric cancer
    • Kwon OH, Park JL, Kim M et al. Aberrant up-regulation of LAMB3 and LAMC2 by promoter demethylation in gastric cancer. Biochem. Biophys. Res. Commun. 406(4), 539-545 (2011).
    • (2011) Biochem. Biophys. Res. Commun. , vol.406 , Issue.4 , pp. 539-545
    • Kwon, O.H.1    Park, J.L.2    Kim, M.3
  • 100
    • 33947315736 scopus 로고    scopus 로고
    • Cancer epigenomics: DNA methylomes and histone-modification maps
    • Esteller M. Cancer epigenomics: DNA methylomes and histone-modification maps. Nat. Rev. Genet. 8(4), 286-298 (2007).
    • (2007) Nat. Rev. Genet. , vol.8 , Issue.4 , pp. 286-298
    • Esteller, M.1
  • 101
    • 58149239686 scopus 로고    scopus 로고
    • Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer
    • Varambally S, Cao Q, Mani RS et al. Genomic loss of microRNA-101 leads to overexpression of histone methyltransferase EZH2 in cancer. Science 322(5908), 1695-1699 (2008).
    • (2008) Science , vol.322 , Issue.5908 , pp. 1695-1699
    • Varambally, S.1    Cao, Q.2    Mani, R.S.3
  • 102
    • 41349104897 scopus 로고    scopus 로고
    • Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells
    • Fujii S, Ochiai A. Enhancer of zeste homolog 2 downregulates E-cadherin by mediating histone H3 methylation in gastric cancer cells. Cancer Sci. 99(4), 738-746 (2008).
    • (2008) Cancer Sci. , vol.99 , Issue.4 , pp. 738-746
    • Fujii, S.1    Ochiai, A.2
  • 103
    • 37849044390 scopus 로고    scopus 로고
    • Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines
    • Meng CF, Zhu XJ, Peng G, Dai DQ. Re-expression of methylation-induced tumor suppressor gene silencing is associated with the state of histone modification in gastric cancer cell lines. World J. Gastroenterol. 13(46), 6166-6171 (2007).
    • (2007) World J. Gastroenterol. , vol.13 , Issue.46 , pp. 6166-6171
    • Meng, C.F.1    Zhu, X.J.2    Peng, G.3    Dai, D.Q.4
  • 104
    • 70449397576 scopus 로고    scopus 로고
    • Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells
    • Meng CF, Zhu XJ, Peng G, Dai DQ. Promoter histone H3 lysine 9 di-methylation is associated with DNA methylation and aberrant expression of p16 in gastric cancer cells. Oncol. Reports 22(5), 1221-1227 (2009).
    • (2009) Oncol. Reports , vol.22 , Issue.5 , pp. 1221-1227
    • Meng, C.F.1    Zhu, X.J.2    Peng, G.3    Dai, D.Q.4
  • 105
    • 33748252848 scopus 로고    scopus 로고
    • Overexpression of phosphorylated histone H3 is an indicator of poor prognosis in gastric adenocarcinoma patients
    • Takahashi H, Murai Y, Tsuneyama K et al. Overexpression of phosphorylated histone H3 is an indicator of poor prognosis in gastric adenocarcinoma patients. Appl. Immunohistochem. Mol. Morphol. 14(3), 296-302 (2006).
    • (2006) Appl. Immunohistochem. Mol. Morphol. , vol.14 , Issue.3 , pp. 296-302
    • Takahashi, H.1    Murai, Y.2    Tsuneyama, K.3
  • 106
    • 0242361623 scopus 로고    scopus 로고
    • Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8
    • Henry KW, Wyce A, Lo WS et al. Transcriptional activation via sequential histone H2B ubiquitylation and deubiquitylation, mediated by SAGA-associated Ubp8. Genes Dev. 17(21), 2648-2663 (2003).
    • (2003) Genes Dev. , vol.17 , Issue.21 , pp. 2648-2663
    • Henry, K.W.1    Wyce, A.2    Lo, W.S.3
  • 107
    • 0344824404 scopus 로고    scopus 로고
    • Histone sumoylation is associated with transcriptional repression
    • Shiio Y, Eisenman RN. Histone sumoylation is associated with transcriptional repression. Proc. Natl Acad. Sci. USA 100(23), 13225-13230 (2003).
    • (2003) Proc. Natl Acad. Sci. USA , vol.100 , Issue.23 , pp. 13225-13230
    • Shiio, Y.1    Eisenman, R.N.2
  • 108
    • 75749101495 scopus 로고    scopus 로고
    • Chromatin remodelling during development
    • Ho L, Crabtree GR. Chromatin remodelling during development. Nature 463(7280), 474-484 (2010).
    • (2010) Nature , vol.463 , Issue.7280 , pp. 474-484
    • Ho, L.1    Crabtree, G.R.2
  • 109
    • 0029618369 scopus 로고
    • ISWI, a member of the SWI2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor
    • Tsukiyama T, Daniel C, Tamkun J, Wu C. ISWI, a member of the SWI2/SNF2 ATPase family, encodes the 140 kDa subunit of the nucleosome remodeling factor. Cell 83(6), 1021-1026 (1995).
    • (1995) Cell , vol.83 , Issue.6 , pp. 1021-1026
    • Tsukiyama, T.1    Daniel, C.2    Tamkun, J.3    Wu, C.4
  • 110
    • 0030839857 scopus 로고    scopus 로고
    • Chromatinremodelling factor CHRAC contains the ATPases ISWI and topoisomerase II
    • Varga-Weisz PD, Wilm M, Bonte E, Dumas K, Mann M, Becker PB. Chromatinremodelling factor CHRAC contains the ATPases ISWI and topoisomerase II. Nature 388(6642), 598-602 (1997).
    • (1997) Nature , vol.388 , Issue.6642 , pp. 598-602
    • Varga-Weisz, P.D.1    Wilm, M.2    Bonte, E.3    Dumas, K.4    Mann, M.5    Becker, P.B.6
  • 111
    • 79959653996 scopus 로고    scopus 로고
    • SWI/SNF nucleosome remodellers and cancer
    • Wilson BG, Roberts CW. SWI/SNF nucleosome remodellers and cancer. Nat. Rev. Cancer 11(7), 481-492 (2011).
    • (2011) Nat. Rev. Cancer , vol.11 , Issue.7 , pp. 481-492
    • Wilson, B.G.1    Roberts, C.W.2
  • 112
    • 84857467474 scopus 로고    scopus 로고
    • Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types
    • Jones S, Li M, Parsons DW et al. Somatic mutations in the chromatin remodeling gene ARID1A occur in several tumor types. Hum. Mutat. 33(1), 100-103 (2012).
    • (2012) Hum. Mutat. , vol.33 , Issue.1 , pp. 100-103
    • Jones, S.1    Li, M.2    Parsons, D.W.3
  • 113
    • 82255183148 scopus 로고    scopus 로고
    • Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer
    • Wang K, Kan J, Yuen St et al. Exome sequencing identifies frequent mutation of ARID1A in molecular subtypes of gastric cancer. Nat. Genet. 43(12), 1219-1223 (2011).
    • (2011) Nat. Genet. , vol.43 , Issue.12 , pp. 1219-1223
    • Wang, K.1    Kan, J.2    Yuen, S.3
  • 114
    • 0035789816 scopus 로고    scopus 로고
    • Increased expression but not genetic alteration of BRG1, a component of the SWI/SNF complex, is associated with the advanced stage of human gastric carcinomas
    • Sentani K, Oue N, Kondo H et al. Increased expression but not genetic alteration of BRG1, a component of the SWI/SNF complex, is associated with the advanced stage of human gastric carcinomas. Pathobiology 69(6), 315-320 (2001).
    • (2001) Pathobiology , vol.69 , Issue.6 , pp. 315-320
    • Sentani, K.1    Oue, N.2    Kondo, H.3
  • 115
    • 36349006592 scopus 로고    scopus 로고
    • Frequent loss of Brm expression in gastric cancer correlates with histologic features and differentiation state
    • Yamamichi N, Inada K, Ichinose M et al. Frequent loss of Brm expression in gastric cancer correlates with histologic features and differentiation state. Cancer Res. 67(22), 10727-10735 (2007).
    • (2007) Cancer Res. , vol.67 , Issue.22 , pp. 10727-10735
    • Yamamichi, N.1    Inada, K.2    Ichinose, M.3
  • 116
    • 81355142141 scopus 로고    scopus 로고
    • Non-coding RNAs in human disease
    • Esteller M. Non-coding RNAs in human disease. Nat. Rev. Genet. 12(12), 861-874 (2011).
    • (2011) Nat. Rev. Genet. , vol.12 , Issue.12 , pp. 861-874
    • Esteller, M.1
  • 117
    • 79960108916 scopus 로고    scopus 로고
    • MiR-9 downregulates CDX2 expression in gastric cancer cells
    • Rotkrua P, Akiyama Y, Hashimoto Y, Otsubo T, Yuasa Y. MiR-9 downregulates CDX2 expression in gastric cancer cells. Int. J. Cancer 129(11), 2611-2620 (2011).
    • (2011) Int. J. Cancer , vol.129 , Issue.11 , pp. 2611-2620
    • Rotkrua, P.1    Akiyama, Y.2    Hashimoto, Y.3    Otsubo, T.4    Yuasa, Y.5
  • 118
    • 79952113135 scopus 로고    scopus 로고
    • Impact of miRNAs in gastrointestinal cancer diagnosis and prognosis
    • Covers the results of miRNA research in gastric and other gastrointestinal cancers until 2010
    • Song B, Ju J. Impact of miRNAs in gastrointestinal cancer diagnosis and prognosis. Expert Rev. Mol. Med. 12, E33 (2010). Covers the results of miRNA research in gastric and other gastrointestinal cancers until 2010.
    • (2010) Expert Rev. Mol. Med. , vol.12
    • Song, B.1    Ju, J.2
  • 119
    • 84856018708 scopus 로고    scopus 로고
    • Genome-wide microRNA profiles identify miR-378 as a serum biomarker for early detection of gastric cancer
    • Liu H, Zhu L, Liu B et al. Genome-wide microRNA profiles identify miR-378 as a serum biomarker for early detection of gastric cancer. Cancer Lett. 316(2), 196-203 (2012).
    • (2012) Cancer Lett. , vol.316 , Issue.2 , pp. 196-203
    • Liu, H.1    Zhu, L.2    Liu, B.3
  • 120
    • 79952101104 scopus 로고    scopus 로고
    • A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis
    • Liu R, Zhang C, Hu Z et al. A five-microRNA signature identified from genome-wide serum microRNA expression profiling serves as a fingerprint for gastric cancer diagnosis. Eur. J. Cancer 47(5), 784-791 (2011).
    • (2011) Eur. J. Cancer , vol.47 , Issue.5 , pp. 784-791
    • Liu, R.1    Zhang, C.2    Hu, Z.3
  • 121
    • 77950370671 scopus 로고    scopus 로고
    • Circulating microRNAs in plasma of patients with gastric cancers
    • Tsujiura M, Ichikawa D, Komatsu S et al. Circulating microRNAs in plasma of patients with gastric cancers. Br. J. Cancer 102(7), 1174-1179 (2010).
    • (2010) Br. J. Cancer , vol.102 , Issue.7 , pp. 1174-1179
    • Tsujiura, M.1    Ichikawa, D.2    Komatsu, S.3
  • 122
    • 80053501436 scopus 로고    scopus 로고
    • Identification of new aberrantly expressed miRNAs in intestinal-type gastric cancer and its clinical significance
    • Li X, Luo F, Li Q et al. Identification of new aberrantly expressed miRNAs in intestinal-type gastric cancer and its clinical significance. Oncol. Rep. 26(6), 1431-1439 (2011).
    • (2011) Oncol. Rep. , vol.26 , Issue.6 , pp. 1431-1439
    • Li, X.1    Luo, F.2    Li, Q.3
  • 123
    • 38449100788 scopus 로고    scopus 로고
    • Expression profile of class I histone deacetylases in human cancer tissues
    • Nakagawa M, Oda Y, Eguchi T et al. Expression profile of class I histone deacetylases in human cancer tissues. Oncol. Rep. 18(4), 769-774 (2007).
    • (2007) Oncol. Rep. , vol.18 , Issue.4 , pp. 769-774
    • Nakagawa, M.1    Oda, Y.2    Eguchi, T.3
  • 124
    • 84860253067 scopus 로고    scopus 로고
    • Expression of SIRT1 in gastric cardiac cancer and its clinicopathologic significance
    • Feng AN, Zhang LH, Fan XS et al. Expression of SIRT1 in gastric cardiac cancer and its clinicopathologic significance. Int. J. Surg. Pathol. 19(6), 743-750 (2011).
    • (2011) Int. J. Surg. Pathol. , vol.19 , Issue.6 , pp. 743-750
    • Feng, A.N.1    Zhang, L.H.2    Fan, X.S.3
  • 125
    • 79851486616 scopus 로고    scopus 로고
    • TIP60 as a potential marker for the malignancy of gastric cancer
    • Sakuraba K, Yokomizo K, Shirahata A et al. TIP60 as a potential marker for the malignancy of gastric cancer. Anticancer Res. 31(1), 77-79 (2011).
    • (2011) Anticancer Res. , vol.31 , Issue.1 , pp. 77-79
    • Sakuraba, K.1    Yokomizo, K.2    Shirahata, A.3
  • 126
    • 62549137804 scopus 로고    scopus 로고
    • Histone acetyltransferase Hbo1: Catalytic activity, cellular abundance, and links to primary cancers
    • Iizuka M, Takahashi Y, Mizzen CA et al. Histone acetyltransferase Hbo1: catalytic activity, cellular abundance, and links to primary cancers. Gene 436(1-2), 108-114 (2009).
    • (2009) Gene , vol.436 , Issue.1-2 , pp. 108-114
    • Iizuka, M.1    Takahashi, Y.2    Mizzen, C.A.3
  • 127
    • 78651359052 scopus 로고    scopus 로고
    • Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c
    • Guo X, Jing C, Li L et al. Down-regulation of VEZT gene expression in human gastric cancer involves promoter methylation and miR-43c. Biochem. Biophys. Res. Commun. 404(2), 622-627 (2011).
    • (2011) Biochem. Biophys. Res. Commun. , vol.404 , Issue.2 , pp. 622-627
    • Guo, X.1    Jing, C.2    Li, L.3
  • 128
    • 84863983345 scopus 로고    scopus 로고
    • Expression levels of microRNA-192 and -215 in gastric carcinoma
    • Chiang Y, Zhou X, Wang Z et al.: Expression levels of microRNA-192 and -215 in gastric carcinoma. Pathol. Oncol. Res. (2011).
    • (2011) Pathol. Oncol. Res.
    • Chiang, Y.1    Zhou, X.2    Wang, Z.3
  • 129
    • 77952299722 scopus 로고    scopus 로고
    • MiR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma
    • Furuta M, Kozaki KI, Tanaka S, Arii S, Imoto I, Inazawa J. miR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma. Carcinogenesis 31(5), 766-776 (2010).
    • (2010) Carcinogenesis , vol.31 , Issue.5 , pp. 766-776
    • Furuta, M.1    Kozaki, K.I.2    Tanaka, S.3    Arii, S.4    Imoto, I.5    Inazawa, J.6
  • 130
    • 78751582416 scopus 로고    scopus 로고
    • Aberrant expression of miR-203 and its clinical significance in gastric and colorectal cancers
    • Chiang Y, Song Y, Wang Z et al. Aberrant expression of miR-203 and its clinical significance in gastric and colorectal cancers. J. Gastrointest. Surg. 15(1), 63-70 (2011).
    • (2011) J. Gastrointest. Surg. , vol.15 , Issue.1 , pp. 63-70
    • Chiang, Y.1    Song, Y.2    Wang, Z.3
  • 131
    • 80755189933 scopus 로고    scopus 로고
    • MiR-429 modulates the expression of c-myc in human gastric carcinoma cells
    • Sun T, Wang C, Xing J, Wu D. miR-429 modulates the expression of c-myc in human gastric carcinoma cells. Eur. J. Cancer 47(17), 2552-2559 (2011).
    • (2011) Eur. J. Cancer , vol.47 , Issue.17 , pp. 2552-2559
    • Sun, T.1    Wang, C.2    Xing, J.3    Wu, D.4
  • 132
    • 84655176719 scopus 로고    scopus 로고
    • Down-regulation of miR-212 expression by DNA hypermethylation in human gastric cancer cells
    • Xu L, Wang F, Xu XF et al. Down-regulation of miR-212 expression by DNA hypermethylation in human gastric cancer cells. Med. Oncol. 28(Suppl. 1), S189-S196 (2011).
    • (2011) Med. Oncol. , vol.28 , Issue.SUPPL. 1
    • Xu, L.1    Wang, F.2    Xu, X.F.3
  • 133
    • 77955717754 scopus 로고    scopus 로고
    • MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion
    • Wang HJ, Ruan HJ, He XJ et al. MicroRNA-101 is down-regulated in gastric cancer and involved in cell migration and invasion. Eur. J. Cancer 46(12), 2295-2303 (2010).
    • (2010) Eur. J. Cancer , vol.46 , Issue.12 , pp. 2295-2303
    • Wang, H.J.1    Ruan, H.J.2    He, X.J.3
  • 134
    • 84867985496 scopus 로고    scopus 로고
    • MicroRNA-148a silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer
    • doi:10.1007/s12032-011-0134-3 Epub ahead of print
    • Zhu A, Xia J, Zuo J et al. MicroRNA-148a silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer. Med. Oncol. doi:10.1007/s12032-011-0134-3 (2011) (Epub ahead of print).
    • (2011) Med. Oncol.
    • Zhu, A.1    Xia, J.2    Zuo, J.3
  • 135
    • 78650762564 scopus 로고    scopus 로고
    • MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation
    • Song YX, Yue ZY, Wang ZN et al. MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation. Mol. Cancer 10, 1 (2011).
    • (2011) Mol. Cancer , vol.10 , pp. 1
    • Song, Y.X.1    Yue, Z.Y.2    Wang, Z.N.3
  • 136
    • 80051785482 scopus 로고    scopus 로고
    • Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer
    • Tsai KW, Wu CW, Hu LY et al. Epigenetic regulation of miR-34b and miR-129 expression in gastric cancer. Int. J. Cancer 129(11), 2600-2610 (2011).
    • (2011) Int. J. Cancer , vol.129 , Issue.11 , pp. 2600-2610
    • Tsai, K.W.1    Wu, C.W.2    Hu, L.Y.3
  • 137
    • 79952706449 scopus 로고    scopus 로고
    • MiR-449 inhibits cell proliferation and is down-regulated in gastric cancer
    • Bou Kheir T, Futoma-Kazmierczak E, Jacobsen A et al. miR-449 inhibits cell proliferation and is down-regulated in gastric cancer. Mol. Cancer 10, 29 (2011).
    • (2011) Mol. Cancer , vol.10 , pp. 29
    • Bou Kheir, T.1    Futoma-Kazmierczak, E.2    Jacobsen, A.3
  • 138
    • 84862703901 scopus 로고    scopus 로고
    • Smad3 regulates E-cadherin via miRNA-200 pathway
    • doi:10.1038/onc.2011.484 Epub ahead of print
    • Ahn SM, Cha JY, Kim J et al. Smad3 regulates E-cadherin via miRNA-200 pathway. Oncogene doi:10.1038/onc.2011.484 (2011) (Epub ahead of print).
    • (2011) Oncogene
    • Ahn, S.M.1    Cha, J.Y.2    Kim, J.3
  • 139
    • 84862776838 scopus 로고    scopus 로고
    • MicroRNA-182 targets cyclic adenosine monophosphate responsive element binding protein 1 (CREB1) and suppresses cell growth in human gastric adenocarcinoma
    • Kong WQ, Bai R, Liu T et al. MicroRNA-182 targets cyclic adenosine monophosphate responsive element binding protein 1 (CREB1) and suppresses cell growth in human gastric adenocarcinoma. FEBS J. 279(7), 1252-1260 (2012).
    • (2012) FEBS J. , vol.279 , Issue.7 , pp. 1252-1260
    • Kong, W.Q.1    Bai, R.2    Liu, T.3
  • 140
    • 84865642499 scopus 로고    scopus 로고
    • Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells
    • Kong D, Piao YS, Yamashita S et al. Inflammation-induced repression of tumor suppressor miR-7 in gastric tumor cells. Oncogene (2011).
    • (2011) Oncogene
    • Kong, D.1    Piao, Y.S.2    Yamashita, S.3
  • 141
    • 80053593567 scopus 로고    scopus 로고
    • MiR-29a inhibits cell proliferation and induces cell cycle arrest through the downregulation of p42.3 in human gastric cancer
    • Cui Y, Su WY, Xing J et al. MiR-29a inhibits cell proliferation and induces cell cycle arrest through the downregulation of p42.3 in human gastric cancer. PLoS ONE 6(10), e25872 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.10
    • Cui, Y.1    Su, W.Y.2    Xing, J.3
  • 142
    • 84860271323 scopus 로고    scopus 로고
    • Down-regulation of miR-125a-3p in human gastric cancer and its clinicopathological significance
    • Hashiguchi Y, Nishida N, Mimori K et al. Down-regulation of miR-125a-3p in human gastric cancer and its clinicopathological significance. Int. J. Oncol. 40(5), 1477-1482 (2012).
    • (2012) Int. J. Oncol. , vol.40 , Issue.5 , pp. 1477-1482
    • Hashiguchi, Y.1    Nishida, N.2    Mimori, K.3
  • 143
    • 79955513982 scopus 로고    scopus 로고
    • MicroRNA-125a-5p is an independent prognostic factor in gastric cancer and inhibits the proliferation of human gastric cancer cells in combination with trastuzumab
    • Nishida N, Mimori K, Fabbri M et al. MicroRNA-125a-5p is an independent prognostic factor in gastric cancer and inhibits the proliferation of human gastric cancer cells in combination with trastuzumab. Clin. Cancer Res. 17(9), 2725-2733 (2011).
    • (2011) Clin. Cancer Res. , vol.17 , Issue.9 , pp. 2725-2733
    • Nishida, N.1    Mimori, K.2    Fabbri, M.3
  • 144
    • 77950250954 scopus 로고    scopus 로고
    • MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta
    • Tsukamoto Y, Nakada C, Noguchi T et al. MicroRNA-375 is downregulated in gastric carcinomas and regulates cell survival by targeting PDK1 and 14-3-3zeta. Cancer Res. 70(6), 2339-2349 (2010).
    • (2010) Cancer Res. , vol.70 , Issue.6 , pp. 2339-2349
    • Tsukamoto, Y.1    Nakada, C.2    Noguchi, T.3
  • 145
    • 78149420582 scopus 로고    scopus 로고
    • Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line
    • Ohshima K, Inoue K, Fujiwara A et al. Let-7 microRNA family is selectively secreted into the extracellular environment via exosomes in a metastatic gastric cancer cell line. PLoS ONE 5(10), e13247 (2011).
    • (2011) PLoS ONE , vol.5 , Issue.10
    • Ohshima, K.1    Inoue, K.2    Fujiwara, A.3
  • 146
    • 79251584345 scopus 로고    scopus 로고
    • NF-κB targets miR-16 and miR-21 in gastric cancer: Involvement of prostaglandin e receptors
    • Shin VY, Jin H, Ng EK et al. NF-κB targets miR-16 and miR-21 in gastric cancer: involvement of prostaglandin E receptors. Carcinogenesis 32(2), 240-245 (2010).
    • (2010) Carcinogenesis , vol.32 , Issue.2 , pp. 240-245
    • Shin, V.Y.1    Jin, H.2    Ng, E.K.3
  • 147
    • 42549169404 scopus 로고    scopus 로고
    • MiR-21 microRNA expression in human gastric carcinomas and its clinical association
    • Chan SH, Wu CW, Li AF, Chi CW, Lin WC. miR-21 microRNA expression in human gastric carcinomas and its clinical association. Anticancer Res. 28(2A), 907-911 (2008).
    • (2008) Anticancer Res. , vol.28 , Issue.2 , pp. 907-911
    • Chan, S.H.1    Wu, C.W.2    Li, A.F.3    Chi, C.W.4    Lin, W.C.5
  • 148
    • 79953225838 scopus 로고    scopus 로고
    • MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro
    • Jin Z, Selaru FM, Cheng Y et al. MicroRNA-192 and -215 are upregulated in human gastric cancer in vivo and suppress ALCAM expression in vitro. Oncogene 30(13), 1577-1585 (2011).
    • (2011) Oncogene , vol.30 , Issue.13 , pp. 1577-1585
    • Jin, Z.1    Selaru, F.M.2    Cheng, Y.3
  • 149
    • 79551511687 scopus 로고    scopus 로고
    • MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis
    • Otsubo T, Akiyama Y, Hashimoto Y, Shimada S, Goto K, Yuasa Y. MicroRNA-126 inhibits SOX2 expression and contributes to gastric carcinogenesis. PLoS ONE 6(1), e16617 (2011).
    • (2011) PLoS ONE , vol.6 , Issue.1
    • Otsubo, T.1    Akiyama, Y.2    Hashimoto, Y.3    Shimada, S.4    Goto, K.5    Yuasa, Y.6
  • 150
    • 84862908996 scopus 로고    scopus 로고
    • Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis
    • Xiao B, Zhu ED, Li N et al. Increased miR-146a in gastric cancer directly targets SMAD4 and is involved in modulating cell proliferation and apoptosis. Oncol. Rep. 27(2), 559-566 (2012).
    • (2012) Oncol. Rep. , vol.27 , Issue.2 , pp. 559-566
    • Xiao, B.1    Zhu, E.D.2    Li, N.3
  • 151
    • 80054847340 scopus 로고    scopus 로고
    • MicroRNAs as a potential prognostic factor in gastric cancer
    • Brenner B, Hoshen MB, Purim O et al. MicroRNAs as a potential prognostic factor in gastric cancer. World J. Gastroenterol. 17(35), 3976-3985 (2011).
    • (2011) World J. Gastroenterol. , vol.17 , Issue.35 , pp. 3976-3985
    • Brenner, B.1    Hoshen, M.B.2    Purim, O.3


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