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Volumn 141, Issue 1, 2014, Pages 148-157

β-catenin regulates Pax3 and Cdx2 for caudal neural tube closure and elongation

Author keywords

Posterior neuropore (PNP); Spina bifida; Wnt catenin signaling

Indexed keywords

BETA CATENIN; COMPLEMENTARY DNA; TRANSCRIPTION FACTOR CDX2; TRANSCRIPTION FACTOR PAX3; WNT PROTEIN;

EID: 84890492806     PISSN: 09501991     EISSN: 14779129     Source Type: Journal    
DOI: 10.1242/dev.101550     Document Type: Article
Times cited : (60)

References (90)
  • 2
    • 70349177596 scopus 로고    scopus 로고
    • Genetic basis of neural tube defects
    • Bassuk, A. G. and Kibar, Z. (2009). Genetic basis of neural tube defects. Semin. Pediatr. Neurol. 16, 101-110.
    • (2009) Semin. Pediatr. Neurol. , vol.16 , pp. 101-110
    • Bassuk, A.G.1    Kibar, Z.2
  • 4
    • 0035034603 scopus 로고    scopus 로고
    • Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development
    • Brault, V., Moore, R., Kutsch, S., Ishibashi, M., Rowitch, D. H., McMahon, A. P., Sommer, L., Boussadia, O. and Kemler, R. (2001). Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development. Development 128, 1253-1264.
    • (2001) Development , vol.128 , pp. 1253-1264
    • Brault, V.1    Moore, R.2    Kutsch, S.3    Ishibashi, M.4    Rowitch, D.H.5    McMahon, A.P.6    Sommer, L.7    Boussadia, O.8    Kemler, R.9
  • 5
    • 84856504393 scopus 로고    scopus 로고
    • TCFs and Wnt/β-catenin signaling: More than one way to throw the switch
    • Cadigan, K. M. (2012). TCFs and Wnt/β-catenin signaling: more than one way to throw the switch. Curr. Top. Dev. Biol. 98, 1-34.
    • (2012) Curr. Top. Dev. Biol. , vol.98 , pp. 1-34
    • Cadigan, K.M.1
  • 6
    • 0036802647 scopus 로고    scopus 로고
    • Axial progenitors with extensive potency are localised to the mouse chordoneural hinge
    • Cambray, N. and Wilson, V. (2002). Axial progenitors with extensive potency are localised to the mouse chordoneural hinge. Development 129, 4855-4866.
    • (2002) Development , vol.129 , pp. 4855-4866
    • Cambray, N.1    Wilson, V.2
  • 7
    • 24644493191 scopus 로고    scopus 로고
    • Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6
    • Carter, M., Chen, X., Slowinska, B., Minnerath, S., Glickstein, S., Shi, L., Campagne, F., Weinstein, H. and Ross, M. E. (2005). Crooked tail (Cd) model of human folate-responsive neural tube defects is mutated in Wnt coreceptor lipoprotein receptor-related protein 6. Proc. Natl. Acad. Sci. USA 102, 12843-12848.
    • (2005) Proc. Natl. Acad. Sci. USA , vol.102 , pp. 12843-12848
    • Carter, M.1    Chen, X.2    Slowinska, B.3    Minnerath, S.4    Glickstein, S.5    Shi, L.6    Campagne, F.7    Weinstein, H.8    Ross, M.E.9
  • 8
    • 0032510049 scopus 로고    scopus 로고
    • Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6
    • Chapman, D. L. and Papaioannou, V. E. (1998). Three neural tubes in mouse embryos with mutations in the T-box gene Tbx6. Nature 391, 695-697.
    • (1998) Nature , vol.391 , pp. 695-697
    • Chapman, D.L.1    Papaioannou, V.E.2
  • 10
    • 84861986053 scopus 로고    scopus 로고
    • Wnt/β-catenin signaling and disease
    • Clevers, H. and Nusse, R. (2012). Wnt/β-catenin signaling and disease. Cell 149, 1192-1205.
    • (2012) Cell , vol.149 , pp. 1192-1205
    • Clevers, H.1    Nusse, R.2
  • 11
    • 73949127068 scopus 로고    scopus 로고
    • Genetics and development of neural tube defects
    • Copp, A. J. and Greene, N. D. (2010). Genetics and development of neural tube defects. J. Pathol. 220, 217-230.
    • (2010) J. Pathol. , vol.220 , pp. 217-230
    • Copp, A.J.1    Greene, N.D.2
  • 12
    • 0141483382 scopus 로고    scopus 로고
    • The genetic basis of mammalian neurulation
    • Copp, A. J., Greene, N. D. and Murdoch, J. N. (2003). The genetic basis of mammalian neurulation. Nat. Rev. Genet. 4, 784-793.
    • (2003) Nat. Rev. Genet. , vol.4 , pp. 784-793
    • Copp, A.J.1    Greene, N.D.2    Murdoch, J.N.3
  • 13
    • 84880329695 scopus 로고    scopus 로고
    • Neural tube defects: Recent advances, unsolved questions, and controversies
    • Copp, A. J., Stanier, P. and Greene, N. D. (2013). Neural tube defects: recent advances, unsolved questions, and controversies. Lancet Neurol. 12, 799-810.
    • (2013) Lancet Neurol. , vol.12 , pp. 799-810
    • Copp, A.J.1    Stanier, P.2    Greene, N.D.3
  • 14
    • 0028959288 scopus 로고
    • The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo
    • Crossley, P. H. and Martin, G. R. (1995). The mouse Fgf8 gene encodes a family of polypeptides and is expressed in regions that direct outgrowth and patterning in the developing embryo. Development 121, 439-451.
    • (1995) Development , vol.121 , pp. 439-451
    • Crossley, P.H.1    Martin, G.R.2
  • 16
    • 80052030805 scopus 로고    scopus 로고
    • Human neural tube defects: Genetic causes and prevention
    • De Marco, P., Merello, E., Cama, A., Kibar, Z. and Capra, V. (2011). Human neural tube defects: genetic causes and prevention. Biofactors 37, 261-268.
    • (2011) Biofactors , vol.37 , pp. 261-268
    • De Marco, P.1    Merello, E.2    Cama, A.3    Kibar, Z.4    Capra, V.5
  • 18
    • 18844422480 scopus 로고    scopus 로고
    • Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives
    • Engleka, K. A., Gitler, A. D., Zhang, M., Zhou, D. D., High, F. A. and Epstein, J. A. (2005). Insertion of Cre into the Pax3 locus creates a new allele of Splotch and identifies unexpected Pax3 derivatives. Dev. Biol. 280, 396-406.
    • (2005) Dev. Biol. , vol.280 , pp. 396-406
    • Engleka, K.A.1    Gitler, A.D.2    Zhang, M.3    Zhou, D.D.4    High, F.A.5    Epstein, J.A.6
  • 19
    • 0025925068 scopus 로고
    • Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3
    • Epstein, D. J., Vekemans, M. and Gros, P. (1991). Splotch (Sp2H), a mutation affecting development of the mouse neural tube, shows a deletion within the paired homeodomain of Pax-3. Cell 67, 767-774.
    • (1991) Cell , vol.67 , pp. 767-774
    • Epstein, D.J.1    Vekemans, M.2    Gros, P.3
  • 20
    • 57149114315 scopus 로고    scopus 로고
    • Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development
    • Etheridge, S. L., Ray, S., Li, S., Hamblet, N. S., Lijam, N., Tsang, M., Greer, J., Kardos, N., Wang, J., Sussman, D. J. et al. (2008). Murine dishevelled 3 functions in redundant pathways with dishevelled 1 and 2 in normal cardiac outflow tract, cochlea, and neural tube development. PLoS Genet. 4, e1000259.
    • (2008) PLoS Genet. , vol.4
    • Etheridge, S.L.1    Ray, S.2    Li, S.3    Hamblet, N.S.4    Lijam, N.5    Tsang, M.6    Greer, J.7    Kardos, N.8    Wang, J.9    Sussman, D.J.10
  • 21
    • 0030899176 scopus 로고    scopus 로고
    • Disruption of Msx-1 and Msx-2 reveals roles for these genes in craniofacial, eye, and axial development
    • Foerst-Potts, L. and Sadler, T. W. (1997). Disruption of Msx-1 and Msx-2 reveals roles for these genes in craniofacial, eye, and axial development. Dev. Dyn. 209, 70-84.
    • (1997) Dev. Dyn. , vol.209 , pp. 70-84
    • Foerst-Potts, L.1    Sadler, T.W.2
  • 22
    • 0030659575 scopus 로고    scopus 로고
    • Genetic patterning of the developing mouse tail at the time of posterior neuropore closure
    • Gofflot, F., Hall, M. and Morriss-Kay, G. M. (1997). Genetic patterning of the developing mouse tail at the time of posterior neuropore closure. Dev. Dyn. 210, 431-445.
    • (1997) Dev. Dyn. , vol.210 , pp. 431-445
    • Gofflot, F.1    Hall, M.2    Morriss-Kay, G.M.3
  • 23
    • 0025875226 scopus 로고
    • Pax-3, a novel murine DNA binding protein expressed during early neurogenesis
    • Goulding, M. D., Chalepakis, G., Deutsch, U., Erselius, J. R. and Gruss, P. (1991). Pax-3, a novel murine DNA binding protein expressed during early neurogenesis. EMBO J. 10, 1135-1147.
    • (1991) EMBO J. , vol.10 , pp. 1135-1147
    • Goulding, M.D.1    Chalepakis, G.2    Deutsch, U.3    Erselius, J.R.4    Gruss, P.5
  • 25
    • 65349125846 scopus 로고    scopus 로고
    • Understanding the causes and prevention of neural tube defects: Insights from the splotch mouse model
    • Greene, N. D., Massa, V. and Copp, A. J. (2009). Understanding the causes and prevention of neural tube defects: Insights from the splotch mouse model. Birth Defects Res. A Clin. Mol. Teratol. 85, 322-330.
    • (2009) Birth Defects Res. A Clin. Mol. Teratol. , vol.85 , pp. 322-330
    • Greene, N.D.1    Massa, V.2    Copp, A.J.3
  • 26
    • 51149118892 scopus 로고    scopus 로고
    • Deciphering the function of canonical Wnt signals in development and disease: Conditional loss-and gain-of-function mutations of beta-catenin in mice
    • Grigoryan, T., Wend, P., Klaus, A. and Birchmeier, W. (2008). Deciphering the function of canonical Wnt signals in development and disease: conditional loss-and gain-of-function mutations of beta-catenin in mice. Genes Dev. 22, 2308-2341.
    • (2008) Genes Dev. , vol.22 , pp. 2308-2341
    • Grigoryan, T.1    Wend, P.2    Klaus, A.3    Birchmeier, W.4
  • 29
    • 33947172588 scopus 로고    scopus 로고
    • Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects
    • Harris, M. J. and Juriloff, D. M. (2007). Mouse mutants with neural tube closure defects and their role in understanding human neural tube defects. Birth Defects Res. A Clin. Mol. Teratol. 79, 187-210.
    • (2007) Birth Defects Res. A Clin. Mol. Teratol. , vol.79 , pp. 187-210
    • Harris, M.J.1    Juriloff, D.M.2
  • 30
    • 77955649698 scopus 로고    scopus 로고
    • An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure
    • Harris, M. J. and Juriloff, D. M. (2010). An update to the list of mouse mutants with neural tube closure defects and advances toward a complete genetic perspective of neural tube closure. Birth Defects Res. A Clin. Mol. Teratol. 88, 653-669.
    • (2010) Birth Defects Res. A Clin. Mol. Teratol. , vol.88 , pp. 653-669
    • Harris, M.J.1    Juriloff, D.M.2
  • 31
    • 73949120429 scopus 로고    scopus 로고
    • Beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos
    • Hierholzer, A. and Kemler, R. (2010). Beta-catenin-mediated signaling and cell adhesion in postgastrulation mouse embryos. Dev. Dyn. 239, 191-199.
    • (2010) Dev. Dyn. , vol.239 , pp. 191-199
    • Hierholzer, A.1    Kemler, R.2
  • 33
    • 0036148208 scopus 로고    scopus 로고
    • Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway
    • Jho, E. H., Zhang, T., Domon, C., Joo, C. K., Freund, J. N. and Costantini, F. (2002). Wnt/beta-catenin/Tcf signaling induces the transcription of Axin2, a negative regulator of the signaling pathway. Mol. Cell. Biol. 22, 1172-1183.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 1172-1183
    • Jho, E.H.1    Zhang, T.2    Domon, C.3    Joo, C.K.4    Freund, J.N.5    Costantini, F.6
  • 34
    • 84867688062 scopus 로고    scopus 로고
    • A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects
    • Juriloff, D. M. and Harris, M. J. (2012). A consideration of the evidence that genetic defects in planar cell polarity contribute to the etiology of human neural tube defects. Birth Defects Res. A Clin. Mol. Teratol. 94, 824-840.
    • (2012) Birth Defects Res. A Clin. Mol. Teratol. , vol.94 , pp. 824-840
    • Juriloff, D.M.1    Harris, M.J.2
  • 35
    • 0034931874 scopus 로고    scopus 로고
    • Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail
    • Kibar, Z., Vogan, K. J., Groulx, N., Justice, M. J., Underhill, D. A. and Gros, P. (2001). Ltap, a mammalian homolog of Drosophila Strabismus/Van Gogh, is altered in the mouse neural tube mutant Loop-tail. Nat. Genet. 28, 251-255.
    • (2001) Nat. Genet. , vol.28 , pp. 251-255
    • Kibar, Z.1    Vogan, K.J.2    Groulx, N.3    Justice, M.J.4    Underhill, D.A.5    Gros, P.6
  • 40
    • 0033833108 scopus 로고    scopus 로고
    • Wnt/(beta)-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine
    • Lickert, H., Domon, C., Huls, G., Wehrle, C., Duluc, I., Clevers, H., Meyer, B. I., Freund, J. N. and Kemler, R. (2000). Wnt/(beta)-catenin signaling regulates the expression of the homeobox gene Cdx1 in embryonic intestine. Development 127, 3805-3813.
    • (2000) Development , vol.127 , pp. 3805-3813
    • Lickert, H.1    Domon, C.2    Huls, G.3    Wehrle, C.4    Duluc, I.5    Clevers, H.6    Meyer, B.I.7    Freund, J.N.8    Kemler, R.9
  • 44
    • 67650230896 scopus 로고    scopus 로고
    • Wnt/beta-catenin signaling: Components, mechanisms, and diseases
    • MacDonald, B. T., Tamai, K. and He, X. (2009). Wnt/beta-catenin signaling: components, mechanisms, and diseases. Dev. Cell 17, 9-26.
    • (2009) Dev. Cell , vol.17 , pp. 9-26
    • McDonald, B.T.1    Tamai, K.2    He, X.3
  • 45
    • 0030801369 scopus 로고    scopus 로고
    • Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system
    • Mansouri, A., Yokota, Y., Wehr, R., Copeland, N. G., Jenkins, N. A. and Gruss, P. (1997). Paired-related murine homeobox gene expressed in the developing sclerotome, kidney, and nervous system. Dev. Dyn. 210, 53-65.
    • (1997) Dev. Dyn. , vol.210 , pp. 53-65
    • Mansouri, A.1    Yokota, Y.2    Wehr, R.3    Copeland, N.G.4    Jenkins, N.A.5    Gruss, P.6
  • 46
    • 0034960731 scopus 로고    scopus 로고
    • Pax3 acts cell autonomously in the neural tube and somites by controlling cell surface properties
    • Mansouri, A., Pla, P., Larue, L. and Gruss, P. (2001). Pax3 acts cell autonomously in the neural tube and somites by controlling cell surface properties. Development 128, 1995-2005.
    • (2001) Development , vol.128 , pp. 1995-2005
    • Mansouri, A.1    Pla, P.2    Larue, L.3    Gruss, P.4
  • 47
    • 0035902050 scopus 로고    scopus 로고
    • LDL-receptor-related protein 6 is a receptor for Dickkopf proteins
    • Mao, B., Wu, W., Li, Y., Hoppe, D., Stannek, P., Glinka, A. and Niehrs, C. (2001). LDL-receptor-related protein 6 is a receptor for Dickkopf proteins. Nature 411, 321-325.
    • (2001) Nature , vol.411 , pp. 321-325
    • Mao, B.1    Wu, W.2    Li, Y.3    Hoppe, D.4    Stannek, P.5    Glinka, A.6    Niehrs, C.7
  • 50
    • 70349123821 scopus 로고    scopus 로고
    • Overlapping function of Lmx1a and Lmx1b in anterior hindbrain roof plate formation and cerebellar growth
    • Mishima, Y., Lindgren, A. G., Chizhikov, V. V., Johnson, R. L. and Millen, K. J. (2009). Overlapping function of Lmx1a and Lmx1b in anterior hindbrain roof plate formation and cerebellar growth. J. Neurosci. 29, 11377-11384.
    • (2009) J. Neurosci. , vol.29 , pp. 11377-11384
    • Mishima, Y.1    Lindgren, A.G.2    Chizhikov, V.V.3    Johnson, R.L.4    Millen, K.J.5
  • 51
    • 13344285959 scopus 로고    scopus 로고
    • Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction
    • Monsoro-Burq, A. H., Wang, E. and Harland, R. (2005). Msx1 and Pax3 cooperate to mediate FGF8 and WNT signals during Xenopus neural crest induction. Dev. Cell 8, 167-178.
    • (2005) Dev. Cell , vol.8 , pp. 167-178
    • Monsoro-Burq, A.H.1    Wang, E.2    Harland, R.3
  • 52
    • 0035888642 scopus 로고    scopus 로고
    • Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification
    • Murdoch, J. N., Doudney, K., Paternotte, C., Copp, A. J. and Stanier, P. (2001). Severe neural tube defects in the loop-tail mouse result from mutation of Lpp1, a novel gene involved in floor plate specification. Hum. Mol. Genet. 10, 2593-2601.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 2593-2601
    • Murdoch, J.N.1    Doudney, K.2    Paternotte, C.3    Copp, A.J.4    Stanier, P.5
  • 54
    • 0031047684 scopus 로고    scopus 로고
    • Positive and negative DNA sequence elements are required to establish the pattern of Pax3 expression
    • Natoli, T. A., Ellsworth, M. K., Wu, C., Gross, K. W. and Pruitt, S. C. (1997). Positive and negative DNA sequence elements are required to establish the pattern of Pax3 expression. Development 124, 617-626.
    • (1997) Development , vol.124 , pp. 617-626
    • Natoli, T.A.1    Ellsworth, M.K.2    Wu, C.3    Gross, K.W.4    Pruitt, S.C.5
  • 55
    • 0037087629 scopus 로고    scopus 로고
    • Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: Implications for Pax-3-dependent development and tumorigenesis
    • Pani, L., Horal, M. and Loeken, M. R. (2002). Rescue of neural tube defects in Pax-3-deficient embryos by p53 loss of function: implications for Pax-3-dependent development and tumorigenesis. Genes Dev. 16, 676-680.
    • (2002) Genes Dev. , vol.16 , pp. 676-680
    • Pani, L.1    Horal, M.2    Loeken, M.R.3
  • 56
    • 0030994305 scopus 로고    scopus 로고
    • Neural tube defects in embryos of diabetic mice: Role of the Pax-3 gene and apoptosis
    • Phelan, S. A., Ito, M. and Loeken, M. R. (1997). Neural tube defects in embryos of diabetic mice: role of the Pax-3 gene and apoptosis. Diabetes 46, 1189-1197.
    • (1997) Diabetes , vol.46 , pp. 1189-1197
    • Phelan, S.A.1    Ito, M.2    Loeken, M.R.3
  • 58
    • 0034727078 scopus 로고    scopus 로고
    • An LDL-receptor-related protein mediates Wnt signalling in mice
    • Pinson, K. I., Brennan, J., Monkley, S., Avery, B. J. and Skarnes, W. C. (2000). An LDL-receptor-related protein mediates Wnt signalling in mice. Nature 407, 535-538.
    • (2000) Nature , vol.407 , pp. 535-538
    • Pinson, K.I.1    Brennan, J.2    Monkley, S.3    Avery, B.J.4    Skarnes, W.C.5
  • 60
    • 84860850893 scopus 로고    scopus 로고
    • Caudal-related homeobox (Cdx) proteindependent integration of canonical Wnt signaling on paired-box 3 (Pax3) neural crest enhancer
    • Sanchez-Ferras, O., Coutaud, B., Djavanbakht Samani, T., Tremblay, I., Souchkova, O. and Pilon, N. (2012). Caudal-related homeobox (Cdx) proteindependent integration of canonical Wnt signaling on paired-box 3 (Pax3) neural crest enhancer. J. Biol. Chem. 287, 16623-16635.
    • (2012) J. Biol. Chem. , vol.287 , pp. 16623-16635
    • Sanchez-Ferras, O.1    Coutaud, B.2    Djavanbakht Samani, T.3    Tremblay, I.4    Souchkova, O.5    Pilon, N.6
  • 61
    • 79955127220 scopus 로고    scopus 로고
    • Cdx mediates neural tube closure through transcriptional regulation of the planar cell polarity gene Ptk7
    • Savory, J. G., Mansfield, M., Rijli, F. M. and Lohnes, D. (2011). Cdx mediates neural tube closure through transcriptional regulation of the planar cell polarity gene Ptk7. Development 138, 1361-1370.
    • (2011) Development , vol.138 , pp. 1361-1370
    • Savory, J.G.1    Mansfield, M.2    Rijli, F.M.3    Lohnes, D.4
  • 62
    • 0030007578 scopus 로고    scopus 로고
    • Regional differences in morphogenesis of the neuroepithelium suggest multiple mechanisms of spinal neurulation in the mouse
    • Shum, A. S. and Copp, A. J. (1996). Regional differences in morphogenesis of the neuroepithelium suggest multiple mechanisms of spinal neurulation in the mouse. Anat. Embryol. (Berl.) 194, 65-73.
    • (1996) Anat. Embryol. (Berl.) , vol.194 , pp. 65-73
    • Shum, A.S.1    Copp, A.J.2
  • 63
    • 78649695726 scopus 로고    scopus 로고
    • Lack of motor neuron differentiation is an intrinsic property of the mouse secondary neural tube
    • Shum, A. S., Tang, L. S., Copp, A. J. and Roelink, H. (2010). Lack of motor neuron differentiation is an intrinsic property of the mouse secondary neural tube. Dev. Dyn. 239, 3192-3203.
    • (2010) Dev. Dyn. , vol.239 , pp. 3192-3203
    • Shum, A.S.1    Tang, L.S.2    Copp, A.J.3    Roelink, H.4
  • 64
    • 0032915460 scopus 로고    scopus 로고
    • Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup
    • Solloway, M. J. and Robertson, E. J. (1999). Early embryonic lethality in Bmp5;Bmp7 double mutant mice suggests functional redundancy within the 60A subgroup. Development 126, 1753-1768.
    • (1999) Development , vol.126 , pp. 1753-1768
    • Solloway, M.J.1    Robertson, E.J.2
  • 66
    • 73949149003 scopus 로고    scopus 로고
    • Cardiac neural crest and outflow tract defects in Lrp6 mutant mice
    • Song, L., Li, Y., Wang, K. and Zhou, C. J. (2010). Cardiac neural crest and outflow tract defects in Lrp6 mutant mice. Dev. Dyn. 239, 200-210.
    • (2010) Dev. Dyn. , vol.239 , pp. 200-210
    • Song, L.1    Li, Y.2    Wang, K.3    Zhou, C.J.4
  • 67
    • 0028800024 scopus 로고
    • Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes
    • Subramanian, V., Meyer, B. I. and Gruss, P. (1995). Disruption of the murine homeobox gene Cdx1 affects axial skeletal identities by altering the mesodermal expression domains of Hox genes. Cell 83, 641-653.
    • (1995) Cell , vol.83 , pp. 641-653
    • Subramanian, V.1    Meyer, B.I.2    Gruss, P.3
  • 68
    • 4444292496 scopus 로고    scopus 로고
    • Combinatorial gene regulation by Bmp and Wnt in zebrafish posterior mesoderm formation
    • Szeto, D. P. and Kimelman, D. (2004). Combinatorial gene regulation by Bmp and Wnt in zebrafish posterior mesoderm formation. Development 131, 3751-3760.
    • (2004) Development , vol.131 , pp. 3751-3760
    • Szeto, D.P.1    Kimelman, D.2
  • 72
    • 84862171364 scopus 로고    scopus 로고
    • The many faces and functions of β-catenin
    • Valenta, T., Hausmann, G. and Basler, K. (2012). The many faces and functions of β-catenin. EMBO J. 31, 2714-2736.
    • (2012) EMBO J. , vol.31 , pp. 2714-2736
    • Valenta, T.1    Hausmann, G.2    Basler, K.3
  • 73
    • 33244475320 scopus 로고    scopus 로고
    • The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice
    • van Nes, J., de Graaff, W., Lebrin, F., Gerhard, M., Beck, F. and Deschamps, J. (2006). The Cdx4 mutation affects axial development and reveals an essential role of Cdx genes in the ontogenesis of the placental labyrinth in mice. Development 133, 419-428.
    • (2006) Development , vol.133 , pp. 419-428
    • van Nes, J.1    de Graaff, W.2    Lebrin, F.3    Gerhard, M.4    Beck, F.5    Deschamps, J.6
  • 74
    • 33749018196 scopus 로고    scopus 로고
    • Planar cell polarity, ciliogenesis and neural tube defects
    • SPEC. NO 2
    • Wallingford, J. B. (2006). Planar cell polarity, ciliogenesis and neural tube defects. Hum. Mol. Genet. 15 Spec. No 2, R227-R234.
    • (2006) Hum. Mol. Genet. , vol.15
    • Wallingford, J.B.1
  • 75
    • 84874365790 scopus 로고    scopus 로고
    • The continuing challenge of understanding, preventing, and treating neural tube defects
    • Wallingford, J. B., Niswander, L. A., Shaw, G. M. and Finnell, R. H. (2013). The continuing challenge of understanding, preventing, and treating neural tube defects. Science 339, 1222002.
    • (2013) Science , vol.339 , pp. 1222002
    • Wallingford, J.B.1    Niswander, L.A.2    Shaw, G.M.3    Finnell, R.H.4
  • 77
    • 33645637038 scopus 로고    scopus 로고
    • The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells
    • Wang, Y., Guo, N. and Nathans, J. (2006b). The role of Frizzled3 and Frizzled6 in neural tube closure and in the planar polarity of inner-ear sensory hair cells. J. Neurosci. 26, 2147-2156.
    • (2006) J. Neurosci. , vol.26 , pp. 2147-2156
    • Wang, Y.1    Guo, N.2    Nathans, J.3
  • 78
    • 78650849731 scopus 로고    scopus 로고
    • The canonical Wnt/β-catenin signaling pathway regulates Fgf signaling for early facial development
    • Wang, Y., Song, L. and Zhou, C. J. (2011). The canonical Wnt/β-catenin signaling pathway regulates Fgf signaling for early facial development. Dev. Biol. 349, 250-260.
    • (2011) Dev. Biol. , vol.349 , pp. 250-260
    • Wang, Y.1    Song, L.2    Zhou, C.J.3
  • 80
    • 0031127789 scopus 로고    scopus 로고
    • Is programmed cell death required for neural tube closure?
    • Weil, M., Jacobson, M. D. and Raff, M. C. (1997). Is programmed cell death required for neural tube closure? Curr. Biol. 7, 281-284.
    • (1997) Curr. Biol. , vol.7 , pp. 281-284
    • Weil, M.1    Jacobson, M.D.2    Raff, M.C.3
  • 81
    • 0036472493 scopus 로고    scopus 로고
    • Pax3 induces cell aggregation and regulates phenotypic mesenchymal-epithelial interconversion
    • Wiggan, O., Fadel, M. P. and Hamel, P. A. (2002). Pax3 induces cell aggregation and regulates phenotypic mesenchymal-epithelial interconversion. J. Cell Sci. 115, 517-529.
    • (2002) J. Cell Sci. , vol.115 , pp. 517-529
    • Wiggan, O.1    Fadel, M.P.2    Hamel, P.A.3
  • 82
    • 0025054992 scopus 로고
    • Expression pattern of the mouse T gene and its role in mesoderm formation
    • Wilkinson, D. G., Bhatt, S. and Herrmann, B. G. (1990). Expression pattern of the mouse T gene and its role in mesoderm formation. Nature 343, 657-659.
    • (1990) Nature , vol.343 , pp. 657-659
    • Wilkinson, D.G.1    Bhatt, S.2    Herrmann, B.G.3
  • 83
    • 45749089286 scopus 로고    scopus 로고
    • Persistent expression of Pax3 in the neural crest causes cleft palate and defective osteogenesis in mice
    • Wu, M., Li, J., Engleka, K. A., Zhou, B., Lu, M. M., Plotkin, J. B. and Epstein, J. A. (2008). Persistent expression of Pax3 in the neural crest causes cleft palate and defective osteogenesis in mice. J. Clin. Invest. 118, 2076-2087.
    • (2008) J. Clin. Invest. , vol.118 , pp. 2076-2087
    • Wu, M.1    Li, J.2    Engleka, K.A.3    Zhou, B.4    Lu, M.M.5    Plotkin, J.B.6    Epstein, J.A.7
  • 84
    • 0032938813 scopus 로고    scopus 로고
    • A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo
    • Yamaguchi, T. P., Bradley, A., McMahon, A. P. and Jones, S. (1999a). A Wnt5a pathway underlies outgrowth of multiple structures in the vertebrate embryo. Development 126, 1211-1223.
    • (1999) Development , vol.126 , pp. 1211-1223
    • Yamaguchi, T.P.1    Bradley, A.2    McMahon, A.P.3    Jones, S.4
  • 85
    • 0033573035 scopus 로고    scopus 로고
    • T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification
    • Yamaguchi, T. P., Takada, S., Yoshikawa, Y., Wu, N. and McMahon, A. P. (1999b). T (Brachyury) is a direct target of Wnt3a during paraxial mesoderm specification. Genes Dev. 13, 3185-3190.
    • (1999) Genes Dev. , vol.13 , pp. 3185-3190
    • Yamaguchi, T.P.1    Takada, S.2    Yoshikawa, Y.3    Wu, N.4    McMahon, A.P.5
  • 88
    • 4444340344 scopus 로고    scopus 로고
    • Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants
    • Zhou, C. J., Pinson, K. I. and Pleasure, S. J. (2004). Severe defects in dorsal thalamic development in low-density lipoprotein receptor-related protein-6 mutants. J. Neurosci. 24, 7632-7639.
    • (2004) J. Neurosci. , vol.24 , pp. 7632-7639
    • Zhou, C.J.1    Pinson, K.I.2    Pleasure, S.J.3
  • 89
    • 57149088848 scopus 로고    scopus 로고
    • Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes
    • Zhou, C. J., Molotkov, A., Song, L., Li, Y., Pleasure, D. E., Pleasure, S. J. and Wang, Y. Z. (2008). Ocular coloboma and dorsoventral neuroretinal patterning defects in Lrp6 mutant eyes. Dev. Dyn. 237, 3681-3689.
    • (2008) Dev. Dyn. , vol.237 , pp. 3681-3689
    • Zhou, C.J.1    Molotkov, A.2    Song, L.3    Li, Y.4    Pleasure, D.E.5    Pleasure, S.J.6    Wang, Y.Z.7
  • 90
    • 73949155182 scopus 로고    scopus 로고
    • Generation of Lrp6 conditional gene-targeting mouse line for modeling and dissecting multiple birth defects/congenital anomalies
    • Zhou, C. J., Wang, Y. Z., Yamagami, T., Zhao, T., Song, L. and Wang, K. (2010). Generation of Lrp6 conditional gene-targeting mouse line for modeling and dissecting multiple birth defects/congenital anomalies. Dev. Dyn. 239, 318-326.
    • (2010) Dev. Dyn. , vol.239 , pp. 318-326
    • Zhou, C.J.1    Wang, Y.Z.2    Yamagami, T.3    Zhao, T.4    Song, L.5    Wang, K.6


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