Up-regulated expression of miR-23a/b targeted the pro-apoptotic Fas in radiation-induced thymic lymphoma

Cellular Physiology and Biochemistry

Volumn 32, Issue 6, 2013, Pages 1729-1740

  Li, Bailong ^a   Sun, Mingjuan ^a   Gao, Fu ^a   Liu, Wen ^a   Yang, Yanyong ^a   Liu, Hu ^a   Cheng, Ying ^a   Liu, Cong ^a   Cai, Jianming ^a  

^a SECOND MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Fas; miR 23; Radiation carcinogenesis; Radiation induced thymic lymphoma

Indexed keywords

FAS ANTIGEN; MICRORNA; MICRORNA 23A; MICRORNA 23B; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CONTROLLED STUDY; GENE EXPRESSION; LYMPHOMA CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN TARGETING; RADIATION CARCINOGENESIS; RADIATION INDUCED THYMIC LYMPHOMA; REAL TIME POLYMERASE CHAIN REACTION; RECEPTOR UPREGULATION; THYMUS LYMPHOMA; 3T3 CELL LINE; ANIMAL TISSUE; BINDING SITE; BIOINFORMATICS; CANCER TISSUE; CELL COUNT; CELL LEVEL; FLUORESCENCE ACTIVATED CELL SORTING; LUCIFERASE ASSAY; MTT ASSAY; PROTEIN EXPRESSION; RADIATION INDUCED NEOPLASM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; TISSUE LEVEL; UPREGULATION;

MUS;

3' UNTRANSLATED REGIONS; ANIMALS; ANTIGENS, CD95; APOPTOSIS; BASE SEQUENCE; BINDING SITES; CELL LINE, TUMOR; CELL PROLIFERATION; DOWN-REGULATION; LYMPHOMA; MICE; MICE, INBRED BALB C; MICRORNAS; NIH 3T3 CELLS; OLIGONUCLEOTIDES, ANTISENSE; RADIATION, IONIZING; SEQUENCE ALIGNMENT; THYMUS NEOPLASMS; UP-REGULATION;

EID: 84890487440     PISSN: 10158987     EISSN: 14219778     Source Type: Journal    
DOI: 10.1159/000356607     Document Type: Article

References (52)

1. Liu C, Gao F, Li B, Mitchel RE, Liu X, Lin J, Zhao L, Cai J: Tlr4 knockout protects mice from radiation-induced thymic lymphoma by downregulation of il6 and mir-21. Leukemia 2011;25:1516-1519.
2. Bartel DP: Micrornas: Target recognition and regulatory functions. Cell 2009;136:215-233.
3. Lanford RE, Hildebrandt-Eriksen ES, Petri A, Persson R, Lindow M, Munk ME, Kauppinen S, Orum H: Therapeutic silencing of microrna-122 in primates with chronic hepatitis c virus infection. Science 2010;327:198-201.
4. Ambros V: The functions of animal micrornas. Nature 2004;431:350-355.
5. Melton C, Judson RL, Blelloch R: Opposing microrna families regulate self-renewal in mouse embryonic stem cells. Nature 2010;463:621-626.
6. Liu C, Zhang C, Lu H, Cai J, Wang Z, Chen J, Liu F, Wu Z, Liu X, Sun W: Poly(i:C) induce bone marrow precursor cells into myeloid-derived suppressor cells. Mol Cell Biochem 2011;358:317-323.
7. Calin GA, Croce CM: Microrna signatures in human cancers. Nat Rev Cancer 2006;6:857-866.
8. Calin GA, Ferracin M, Cimmino A, Di Leva G, Shimizu M, Wojcik SE, Iorio MV, Visone R, Sever NI, Fabbri M, Iuliano R, Palumbo T, Pichiorri F, Roldo C, Garzon R, Sevignani C, Rassenti L, Alder H, Volinia S, Liu CG, Kipps TJ, Negrini M, Croce CM: A microrna signature associated with prognosis and progression in chronic lymphocytic leukemia. New Engl J Med 2005;353:1793-1801.
9. Mayr C, Hemann MT, Bartel DP: Disrupting the pairing between let-7 and hmga2 enhances oncogenic transformation. Science 2007;315:1576-1579.
10. Mi S, Lu J, Sun M, Li Z, Zhang H, Neilly MB, Wang Y, Qian Z, Jin J, Zhang Y, Bohlander SK, Le Beau MM, Larson RA, Golub TR, Rowley JD, Chen J: Microrna expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia. Proc Natl Acad Sci USA 2007;104:19971-19976.
11. Gottardo F, Liu CG, Ferracin M, Calin GA, Fassan M, Bassi P, Sevignani C, Byrne D, Negrini M, Pagano F, Gomella LG, Croce CM, Baffa R: Micro-rna profiling in kidney and bladder cancers. Urol Oncol 2007;25:387-392.
12. Volinia S, Calin GA, Liu CG, Ambs S, Cimmino A, Petrocca F, Visone R, Iorio M, Roldo C, Ferracin M, Prueitt RL, Yanaihara N, Lanza G, Scarpa A, Vecchione A, Negrini M, Harris CC, Croce CM: A microrna expression signature of human solid tumors defines cancer gene targets. Proc Natl Acad Sci USA 2006;103:2257-2261.
13. Ciafre SA, Galardi S, Mangiola A, Ferracin M, Liu CG, Sabatino G, Negrini M, Maira G, Croce CM, Farace MG: Extensive modulation of a set of micrornas in primary glioblastoma. Biochem Bioph Res Co 2005;334:1351-1358.
14. Bloomston M, Frankel WL, Petrocca F, Volinia S, Alder H, Hagan JP, Liu CG, Bhatt D, Taccioli C, Croce CM: Microrna expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. JAMA 2007;297:1901-1908.
15. Marsh EE, Lin Z, Yin P, Milad M, Chakravarti D, Bulun SE: Differential expression of microrna species in human uterine leiomyoma versus normal myometrium. Fertil Steri 2008;89:1771-1776.
16. Huang S, He X, Ding J, Liang L, Zhao Y, Zhang Z, Yao X, Pan Z, Zhang P, Li J, Wan D, Gu J: Upregulation of mir-23a approximately 27a approximately 24 decreases transforming growth factor-beta-induced tumor-suppressive activities in human hepatocellular carcinoma cells. Int J Cancer 2008;123:972-978.
17. Porkka KP, Pfeiffer MJ, Waltering KK, Vessella RL, Tammela TL, Visakorpi T: Microrna expression profiling in prostate cancer. Cancer Res 2007;67:6130-6135.
18. Barcellos-Hoff MH, Park C, Wright EG: Radiation and the microenvironment - tumorigenesis and therapy. Nat Rev Cancer 2005;5:867-875.
19. Thoms J, Goda JS, Zlotta AR, Fleshner NE, van der Kwast TH, Supiot S, Warde P, Bristow RG: Neoadjuvant radiotherapy for locally advanced and high-risk prostate cancer. Nat Rev Clin Oncol 2011;8:107-113.
20. Bewley DK: Pions and heavy ions in radiotherapy. Nature 1972;237:17-19 passim.
21. Dange P, Sarma H, Pandey BN, Mishra KP: Radiation-induced incidence of thymic lymphoma in mice and its prevention by antioxidants. J Environ Pathol Toxicol Oncol 2007;26:273-279.
22. Villa-Morales M, Santos J, Fernandez-Piqueras J: Functional fas (cd95/apo-1) promoter polymorphisms in inbred mouse strains exhibiting different susceptibility to gamma-radiation-induced thymic lymphoma. Oncogene 2006;25:2022-2029.
23. Fu Z, Huang D, Cai J, Chen Q, Han L, Li B, Wang F, Gao J: Expression changes of erk1/2, stat3 and shp-2 in bone marrow cells from gamma-ray induced leukemia mice. J Radiat Res 2006;47:121-130.
24. Liu C, Li B, Cheng Y, Lin J, Hao J, Zhang S, Mitchel RE, Sun D, Ni J, Zhao L, Gao F, Cai J: Mir-21 plays an important role in radiation induced carcinogenesis in balb/c mice by directly targeting the tumor suppressor gene big-h3. Int J Biol Sci 2011;7:347-363.
25. Liu C, Zhang C, Mitchel RE, Cui J, Lin J, Yang Y, Liu X, Cai J: A critical role of toll-like receptor 4 (tlr4) and its' in vivo ligands in basal radio-resistance. Cell Death Dis 2013;4:e649.
26. Liu C, Lin J, Zhao L, Yang Y, Gao F, Li B, Cui J, Cai J: Gamma-ray irradiation impairs dendritic cell migration to ccl19 by down-regulation of ccr7 and induction of cell apoptosis. Int J Biol Sci 2011;7:168-179.
27. Liu C, Zhou C, Gao F, Cai S, Zhang C, Zhao L, Zhao F, Cao F, Lin J, Yang Y, Ni J, Jia J, Wu W, Zhou L, Cui J, Zhang W, Li B, Cai J: Mir-34a in age and tissue related radio-sensitivity and serum mir-34a as a novel indicator of radiation injury. Int J Biol Sci 2011;7:221-233.
28. Hao J, Zhang S, Zhou Y, Hu X, Shao C: Microrna 483-3p suppresses the expression of dpc4/smad4 in pancreatic cancer. FEBS Lett 2011;585:207-213.
29. Hao J, Zhang S, Zhou Y, Liu C, Hu X, Shao C: Microrna 421 suppresses dpc4/smad4 in pancreatic cancer. Biochem Biophys Res Commun 2011;406:552-557.
30. Zhang S, Hao J, Xie F, Hu X, Liu C, Tong J, Zhou J, Wu J, Shao C: Downregulation of mir-132 by promoter methylation contributes to pancreatic cancer development. Carcinogenesis 2011;32:1183-1189.
31. Zhang Y, Wang YG, Zhang Q, Liu XJ, Liu X, Jiao L, Zhu W, Zhang ZH, Zhao XL, He C: Interaction of mint2 with trka is involved in regulation of nerve growth factor-induced neurite outgrowth. J Biol Chem 2009;284:12469-12479.
32. Su S, Li Y, Luo Y, Sheng Y, Su Y, Padia RN, Pan ZK, Dong Z, Huang S: Proteinase-activated receptor 2 expression in breast cancer and its role in breast cancer cell migration. Oncogene 2009;28:3047-3057.
33. Rui Y, Liu X, Li N, Jiang Y, Chen G, Cao X, Wang J: Pecam-1 ligation negatively regulates tlr4 signaling in macrophages. J Immunol 2007;179:7344-7351.
34. Zhang Y, Zhang JW, Lv GY, Xie SL, Wang GY: Effects of stat3 gene silencing and rapamycin on apoptosis in hepatocarcinoma cells. Int J Med Sci 2012;9:216-224.
35. Chen T, Guo J, Yang M, Han C, Zhang M, Chen W, Liu Q, Wang J, Cao X: Cyclosporin a impairs dendritic cell migration by regulating chemokine receptor expression and inhibiting cyclooxygenase-2 expression. Blood 2004;103:413-421.
36. Ohl L, Mohaupt M, Czeloth N, Hintzen G, Kiafard Z, Zwirner J, Blankenstein T, Henning G, Forster R: Ccr7 governs skin dendritic cell migration under inflammatory and steady-state conditions. Immunity 2004;21:279-288.
37. Zhang M, Tang H, Guo Z, An H, Zhu X, Song W, Guo J, Huang X, Chen T, Wang J, Cao X: Splenic stroma drives mature dendritic cells to differentiate into regulatory dendritic cells. Nat Immunol 2004;5:1124-1133.
38. He L, He X, Lowe SW, Hannon GJ: Micrornas join the p53 network-another piece in the tumour-suppression puzzle. Nat Rev Cancer 2007;7:819-822.
39. Nicoloso MS, Spizzo R, Shimizu M, Rossi S, Calin GA: Micrornas-the micro steering wheel of tumour metastases. Nat Rev Cancer 2009;9:293-302.
40. Hammond SM, Sharpless NE: Hmga2, micrornas, and stem cell aging. Cell 2008;135:1013-1016.
41. Bartel DP: Micrornas: Genomics, biogenesis, mechanism, and function. Cell 2004;116:281-297.
42. Chen CZ, Li L, Lodish HF, Bartel DP: Micrornas modulate hematopoietic lineage differentiation. Science 2004;303:83-86.
43. Little JB: Radiation carcinogenesis. Carcinogenesis 2000;21:397-404.
44. Bueno MJ, Gomez de Cedron M, Gomez-Lopez G, Perez de Castro I, Di Lisio L, Montes-Moreno S, Martinez N, Guerrero M, Sanchez-Martinez R, Santos J, Pisano DG, Piris MA, Fernandez-Piqueras J, Malumbres M: Combinatorial effects of micrornas to suppress the myc oncogenic pathway. Blood 2011;117:6255-6266.
45. Bueno MJ, Perez de Castro I, Gomez de Cedron M, Santos J, Calin GA, Cigudosa JC, Croce CM, Fernandez- Piqueras J, Malumbres M: Genetic and epigenetic silencing of microrna-203 enhances abl1 and bcr-abl1 oncogene expression. Cancer Cell 2008;13:496-506.
46. Wang B, Hsu SH, Frankel W, Ghoshal K, Jacob ST: Stat3-mediated activation of microrna-23a suppresses gluconeogenesis in hepatocellular carcinoma by down-regulating glucose-6-phosphatase and peroxisome proliferator-activated receptor gamma, coactivator 1 alpha. Hepatology 2012;56:186-197.
47. Zhou Q, Gallagher R, Ufret-Vincenty R, Li X, Olson EN, Wang S: Regulation of angiogenesis and choroidal neovascularization by members of microrna-23∼27∼24 clusters. Proc Natl Acad Sci USA 2011;108:8287-8292.
48. Zhu LH, Liu T, Tang H, Tian RQ, Su C, Liu M, Li X: Microrna-23a promotes the growth of gastric adenocarcinoma cell line mgc803 and downregulates interleukin-6 receptor. FEBS J 2010;277:3726-3734.
49. Kawasaki H, Taira K: Hes1 is a target of microrna-23 during retinoic-acid-induced neuronal differentiation of nt2 cells. Nature 2003;423:838-842.
50. Lin H, Qian J, Castillo AC, Long B, Keyes KT, Chen G, Ye Y: Effect of mir-23 on oxidant-induced injury in human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci 2011;52:6308-6314.
51. Krammer PH: Cd95's deadly mission in the immune system. Nature 2000;407:789-795.
52. Santos J, Herranz M, Fernandez M, Vaquero C, Lopez P, Fernandez-Piqueras J: Evidence of a possible epigenetic inactivation mechanism operating on a region of mouse chromosome 19 in gamma-radiation-induced thymic lymphomas. Oncogene 2001;20:2186-2189.