Effect of miR-23 on Oxidant-induced injury in human retinal pigment epithelial cells

Investigative Ophthalmology and Visual Science

Volumn 52, Issue 9, 2011, Pages 6308-6314

  Lin, Haijiang ^a   Qian, Jinqiao ^b,c   Castillo, Alexander C ^b   Long, Bo ^b   Keyes, Kyle T ^b   Chen, Guanglin ^b   Ye, Yumei ^b  

^a UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^b University of Texas Medical Branch School of Medicine   (United States)

^c KUNMING MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; CASPASE 3; CYTOCHROME C; FAS ANTIGEN; LACTATE DEHYDROGENASE; MICRORNA; MICRORNA 23A; UNCLASSIFIED DRUG; AIFM1 PROTEIN, HUMAN; HYDROGEN PEROXIDE; MIRN23 MICRORNA, HUMAN; OXIDIZING AGENT; TERT BUTYL HYDROPEROXIDE;

3' UNTRANSLATED REGION; APOPTOSIS; ARTICLE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA FRAGMENTATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; HUMAN CELL; NORTHERN BLOTTING; OXIDATIVE STRESS; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RETINA MACULA AGE RELATED DEGENERATION; WESTERN BLOTTING; AGED; CELL CULTURE; DONOR; DRUG EFFECT; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETIC TRANSFECTION; GENETICS; METABOLISM; MIDDLE AGED; MITOCHONDRION; PATHOLOGY; PHYSIOLOGY; RETINA MACULA DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

AGED; AGED, 80 AND OVER; ANTIGENS, CD95; APOPTOSIS; APOPTOSIS INDUCING FACTOR; BLOTTING, NORTHERN; BLOTTING, WESTERN; CASPASE 3; CELL SURVIVAL; CELLS, CULTURED; CYTOCHROMES C; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; HUMANS; HYDROGEN PEROXIDE; MACULAR DEGENERATION; MICRORNAS; MIDDLE AGED; MITOCHONDRIA; OXIDANTS; OXIDATIVE STRESS; RETINAL PIGMENT EPITHELIUM; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TERT-BUTYLHYDROPEROXIDE; TISSUE DONORS; TRANSFECTION;

EID: 80053435752     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.10-6632     Document Type: Article

References (54)

1. Bartel DP. MicroRNAs: genomics, biogenesis, mechanism, and function. Cell. 2004;116:281-297.
2. Divakaran V, Mann DL. The emerging role of microRNAs in cardiac remodeling and heart failure. Circ Res. 2008;103:1072-1083.
3. van Rooij E, Olson EN. MicroRNAs: powerful new regulators of heart disease and provocative therapeutic targets. J Clin Invest. 2007:2369-2376.
4. Karali M, Peluso I, Marigo V, Banfi S. Identification and characterization of microRNAs expressed in the mouse eye. Invest Ophthalmol Vis Sci. 2007;48:509-515.
5. Li X, Carthew RW. A microRNA mediates EGF receptor signaling and promotes photoreceptor differentiation in the Drosophila eye. Cell. 2005;123:1267-1277.
6. Eiring AM, Harb JG, Neviani P, et al. miR-328 functions as an RNA decoy to modulate hnRNP E2 regulation of mRNA translation in leukemic blasts. Cell. 2010;140:652-665.
7. Martello G, Rosato A, Ferrari F, et al. A MicroRNA targeting dicer for metastasis control. Cell. 2010;141:1195-1207.
8. Loscher CJ, Hokamp K, Wilson JH, et al. A common microRNA signature in mouse models of retinal degeneration. Exp Eye Res. 2008;87:529-534.
9. Cheng Y, Liu X, Zhang S, Lin Y, Yang J, Zhang C. MicroRNA-21 protects against the H(2)O(2)-induced injury on cardiac myocytes via its target gene PDCD4. J Mol Cell Cardiol. 2009;47:5-14.
10. Tang Y, Zheng J, Sun Y, Wu Z, Liu Z, Huang G. MicroRNA-1 regulates cardiomyocyte apoptosis by targeting Bcl-2. Int Heart J. 2009;50:377-387.
11. Winkler BS, Boulton ME, Gottsch JD, Sternberg P. Oxidative damage and age-related macular degeneration. Mol Vis. 1999;5:32.
12. Hollyfield JG. Age-related macular degeneration: the molecular link between oxidative damage, tissue-specific inflammation and outer retinal disease: the Proctor lecture. Invest Ophthalmol Vis Sci. 2010;51:1275-1281.
13. Cai J, Wu M, Nelson KC, Sternberg P Jr, Jones DP. Oxidant-induced apoptosis in cultured human retinal pigment epithelial cells. Invest Ophthalmol Vis Sci. 1999;40:959-966.
14. Kim MH, Chung J, Yang JW, Chung SM, Kwag NH, Yoo JS. Hydrogen peroxide-induced cell death in a human retinal pigment epithelial cell line, ARPE-19. Korean J Ophthalmol. 2003; 17:19-28.
15. Weigel AL, Handa JT, Hjelmeland LM. Microarray analysis of H2O2-, HNE-, or tBH-treated ARPE-19 cells. Free Radic Biol Med. 2002;33:1419-1432.
16. Pocrnich CE, Liu H, Feng M, Peng T, Feng Q, Hutnik CM. p38 mitogen-activated protein kinase protects human retinal pigment epithelial cells exposed to oxidative stress. Can J Ophthalmol. 2009;44:431-436.
17. Zareba M, Raciti MW, Henry MM, Sarna T, Burke JM. Oxidative stress in ARPE-19 cultures: do melanosomes confer cytoprotection? Free Radic Biol Med. 2006;40:87-100.
18. Ashkenazi A, Dixit VM. Apoptosis control by death and decoy receptors. Curr Opin Cell Biol. 1999;11:255-260.
19. Dunaief JL, Dentchev T, Ying GS, Milam AH. The role of apoptosis in age-related macular degeneration. Arch Ophthalmol. 2002;120: 1435-1442.
20. Lin ST, Fu YH. miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination. Dis Model Mech. 2009; 2:178-188.
21. Cheng AM, Byrom MW, Shelton J, Ford LP. Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis. Nucleic Acids Res. 2005;33:1290-1297.
22. Kawasaki H, Taira K. Hes1 is a target of microRNA-23 during retinoic-acid-induced neuronal differentiation of NT2 cells. Nature. 2003;423:838-842.
23. Gao P, Tchernyshyov I, Chang TC, et al. c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism. Nature. 2009;458:762-765.
24. Ye Y, Hu Z, Lin Y, Zhang C, Perez-Polo JR. Downregulation of microRNA-29 by antisense inhibitors and a PPAR-gamma agonist protects against myocardial ischemia-reperfusion injury. Cardiovasc Res. 2010;87:535-544.
25. Cheng Y, Ji R, Yue J, et al. MicroRNAs are aberrantly expressed in hypertrophic heart: do they play a role in cardiac hypertrophy? Am J Pathol. 2007;170:1831-1840.
26. Ji R, Cheng Y, Yue J, et al. MicroRNA expression signature and antisense-mediated depletion reveal an essential role of MicroRNA in vascular neointimal lesion formation. Circ Res. 2007;100:1579-1588.
27. Kutty RK, Samuel W, Jaworski C, et al. MicroRNA expression in human retinal pigment epithelial (ARPE-19) cells: increased expression of microRNA-9 by N-(4-hydroxyphenyl)retinamide. Mol Vis. 2010;16:1475-1486.
28. Faghiri Z, Bazan NG. PI3K/Akt and mTOR/p70S6K pathways mediate neuroprotectin D1-induced retinal pigment epithelial cell survival during oxidative stress-induced apoptosis. Exp Eye Res. 2010;90:718-725.
29. Tsao YP, Ho TC, Chen SL, Cheng HC. Pigment epithelium-derived factor inhibits oxidative stress-induced cell death by activation of extracellular signal-regulated kinases in cultured retinal pigment epithelial cells. Life Sci. 2006;79:545-550.
30. Bose K, Bhaumik G, Ghosh R. Chronic low dose exposure to hydrogen peroxide changes sensitivity of V79 cells to different damaging agents. Indian J Exp Biol. 2003;41:832-836.
31. Garg TK, Chang JY. Oxidative stress causes ERK phosphorylation and cell death in cultured retinal pigment epithelium: prevention of cell death by AG126 and 15-deoxy-delta 12, 14-PGJ2. BMC Ophthalmol. 2003;3:5.
32. Watanabe M, Hitomi M, van der Wee K, et al. The pros and cons of apoptosis assays for use in the study of cells, tissues, and organs. Microsc Microanal. 2002;8:375-391.
33. Stadelmann C, Lassmann H. Detection of apoptosis in tissue sections. Cell Tissue Res. 2000;301:19-31.
34. Chang HY, Yang X. Proteases for cell suicide: functions and regulation of caspases. Microbiol Mol Biol Rev. 2000;64:821-846.
35. Joza N, Susin SA, Daugas E, et al. Essential role of the mitochondrial apoptosis-inducing factor in programed cell death. Nature. 2001; 410:549-554.
36. Kasibhatla S, Genestier L, Green DR. Regulation of fas-ligand expression during activation-induced cell death in T lymphocytes via nuclear factor kappaB. J Biol Chem. 1999;274:987-992.
37. Facchinetti F, Furegato S, Terrazzino S, Leon A. H(2)O(2) induces upregulation of Fas and Fas ligand expression in NGF-differentiated PC12 cells: modulation by cAMP. J Neurosci Res. 2002;69: 178-188.
38. Cai J, Nelson KC, Wu M, Sternberg P Jr, Jones DP. Oxidative damage and protection of the RPE. Prog Retin Eye Res. 2000;19: 205-221.
39. Williams DL. Oxidative stress and the eye. Vet Clin North Am Small Anim Pract. 2008;38:179-192, vii.
40. Chhabra R, Adlakha YK, Hariharan M, Scaria V, Saini N. Upregulation of miR-23a-27a-24-2 cluster induces caspase-dependent and-independent apoptosis in human embryonic kidney cells. PLoS One. 2009;4:e5848.
41. Wiktorowska-Owczarek A, Nowak JZ. Pathogenesis and prophylaxis of AMD: focus on oxidative stress and antioxidants [in Polish]. Postepy Hig Med Dosw (Online) 2010;64:333-343.
42. Janik-Papis K, Ulinska M, Krzyzanowska A, et al. Role of oxidative mechanisms in the pathogenesis of age-related macular degeneration (in Polish). Klin Oczna 2009;111:168-173.
43. He S, Yaung J, Kim YH, Barron E, Ryan SJ, Hinton DR. Endoplasmic reticulum stress induced by oxidative stress in retinal pigment epithelial cells. Graefes Arch Clin Exp Ophthalmol. 2008;246: 677-683.
44. Weigel AL, Ida H, Boylan SA, Hjelmeland LM. Acute hyperoxiainduced transcriptional response in the mouse RPE/choroid. Free Radic Biol Med. 2003;35:465-474.
45. Joffre C, Leclere L, Buteau B, et al. Oxysterols induced inflammation and oxidation in primary porcine retinal pigment epithelial cells. Curr Eye Res. 2007;32:271-280.
46. Alizadeh M, Wada M, Gelfman CM, Handa JT, Hjelmeland LM. Downregulation of differentiation specific gene expression by oxidative stress in ARPE-19 cells. Invest Ophthalmol Vis Sci. 2001; 42:2706-2713.
47. Cerda S, Weitzman SA. Influence of oxygen radical injury on DNA methylation. Mutat Res. 1997;386:141-152.
48. Vandenbroucke K, Robbens S, Vandepoele K, Inze D, Van de Peer Y, Van Breusegem F. Hydrogen peroxide-induced gene expression across kingdoms: a comparative analysis. Mol Biol Evol. 2008;25: 507-516.
49. Halbeisen RE, Galgano A, Scherrer T, Gerber AP. Post-transcriptional gene regulation: from genome-wide studies to principles. Cell Mol Life Sci. 2008;65:798-813.
50. Jiang S, Wu MW, Sternberg P, Jones DP. Fas mediates apoptosis and oxidant-induced cell death in cultured hRPE cells. Invest Ophthalmol Vis Sci. 2000;41:645-655.
51. Nagata S. Apoptosis by death factor. Cell. 1997;88:355-365.
52. Chinnaiyan AM, Dixit VM. Portrait of an executioner: the molecular mechanism of FAS/APO-1-induced apoptosis. Semin Immunol. 1997;9:69-76.
53. Hinton DR, He S, Lopez PF. Apoptosis in surgically excised choroidal neovascular membranes in age-related macular degeneration. Arch Ophthalmol. 1998;116:203-209.
54. Cao X, Liu M, Tuo J, Shen D, Chan CC. The effects of quercetin in cultured human RPE cells under oxidative stress and in Ccl2/ Cx3cr1 double deficient mice. Exp Eye Res. 2010;91:15-25.