Connexin43 confers Temozolomide resistance in human glioma cells by modulating the mitochondrial apoptosis pathway

Neuropharmacology

Volumn 75, Issue , 2013, Pages 539-548

  Gielen, Paul R ^a,b   Aftab, Qurratulain ^a   Ma, Noreen ^a   Chen, Vincent C ^a,c   Hong, Xiaoting ^a   Lozinsky, Shannon ^a   Naus, Christian C ^a   Sin, Wun Chey ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^c BRITISH COLUMBIA CANCER AGENCY   (Canada)

Author keywords

Cx43; Cytochrome C; Glioma; TMZ

Indexed keywords

CONNEXIN 43; CYTOCHROME C; MUTANT PROTEIN; PROTEIN BAX; PROTEIN BCL 2; TEMOZOLOMIDE;

APOPTOSIS; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; DRUG EFFICACY; DRUG SENSITIZATION; DRUG TARGETING; ENZYME RELEASE; GENE SILENCING; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION;

CX43; CYTOCHROME C; GLIOMA; TMZ;

ANALYSIS OF VARIANCE; ANNEXIN A5; ANTINEOPLASTIC AGENTS, ALKYLATING; APOPTOSIS; BRAIN NEOPLASMS; CELL LINE, TUMOR; CONNEXIN 43; CYTOCHROMES C; DACARBAZINE; DOSE-RESPONSE RELATIONSHIP, DRUG; FLUORESCEINS; GLIOMA; HUMANS; MITOCHONDRIA; MUTATION; PHOSPHORYLATION; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TIME FACTORS; TRANSFECTION;

EID: 84890434993     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2013.05.002     Document Type: Article

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